#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01705 uniprotkb:Q3TKT4 intact:EBI-1392707|uniprotkb:Q06007|uniprotkb:Q61905|uniprotkb:Q99JC2|uniprotkb:Q9QW58|uniprotkb:Q9R0X7|uniprotkb:Q3TZW2|uniprotkb:Q3U3Y2|uniprotkb:Q7TQ50|uniprotkb:Q7TQ51|uniprotkb:Q7TQ52|uniprotkb:Q8K428|ensembl:ENSMUSP00000028288 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:notc1_mouse(display_long)|uniprotkb:Notch1(gene name)|psi-mi:Notch1(display_short)|uniprotkb:Motch(gene name synonym)|uniprotkb:Motch A(gene name synonym)|uniprotkb:p300(gene name synonym)|uniprotkb:mT14(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15618091|imex:IM-22495-1|dip:DIP-196270E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032740.3|dip:DIP-214N|ensembl:ENSMUSG00000026923(gene)|ensembl:ENSMUST00000028288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003264"(regulation of cardioblast proliferation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1YMP|rcsb pdb:2QC9|rcsb pdb:2RQZ|rcsb pdb:2RR0|rcsb pdb:2RR2|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:5KY0|rcsb pdb:5KY4|rcsb pdb:5KY8|rcsb pdb:5KY9|reactome:R-MMU-1912420|reactome:R-MMU-2122947|reactome:R-MMU-2122948|reactome:R-MMU-350054|reactome:R-MMU-8941856 refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:VOWlSJ0z/YkR4qWQ6MHjD/CVitg10090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:dFbmGQEvNKbft2bo5by6O5H99cU false myc tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6P9Z1 uniprotkb:P31266 intact:EBI-7525857|uniprotkb:Q9CX89|intact:MINT-4616110|uniprotkb:Q9DB99|uniprotkb:Q921D3|ensembl:ENSMUSP00000030791 intact:EBI-1392666|uniprotkb:Q80UN8|uniprotkb:Q8C4Z3|ensembl:ENSMUSP00000040694 psi-mi:smrd3_mouse(display_long)|uniprotkb:Smarcd3(gene name)|psi-mi:Smarcd3(display_short)|uniprotkb:Baf60c(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:suh_mouse(display_long)|uniprotkb:Rbpj(gene name)|psi-mi:Rbpj(display_short)|uniprotkb:Igkjrb1(gene name synonym)|uniprotkb:Igkrsbp(gene name synonym)|uniprotkb:Rbpsuh(gene name synonym)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15618110|imex:IM-22495-2|dip:DIP-196268E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080167.3|ensembl:ENSMUSG00000028949(gene)|ensembl:ENSMUST00000030791(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|reactome:R-MMU-3214858|reactome:R-MMU-400206|reactome:R-MMU-8939243|reactome:R-MMU-9707564|dip:DIP-48886N refseq:NP_001074396.1|refseq:NP_033061.3|dip:DIP-171N|ensembl:ENSMUSG00000039191(gene)|ensembl:ENSMUST00000037618(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001947"(heart looping)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|rcsb pdb:3BRG|rcsb pdb:3IAG|rcsb pdb:4J2X|rcsb pdb:5EG6|rcsb pdb:6DKS|rcsb pdb:6WQU|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856 psi-mi:"MI:0465"(dip) comment:mint|comment:homomint|function:Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:5BEcU8cyfZR0UDJLvhsMwr9p18w10090 rogid:6e2XZZX+zWA0UexPo1D0+3Hv08Y10090 rigid:3m+p9djY7fRtrceztetCsDNHw8Y false - flag tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01705 uniprotkb:Q6P9Z1 intact:EBI-1392707|uniprotkb:Q06007|uniprotkb:Q61905|uniprotkb:Q99JC2|uniprotkb:Q9QW58|uniprotkb:Q9R0X7|uniprotkb:Q3TZW2|uniprotkb:Q3U3Y2|uniprotkb:Q7TQ50|uniprotkb:Q7TQ51|uniprotkb:Q7TQ52|uniprotkb:Q8K428|ensembl:ENSMUSP00000028288 intact:EBI-7525857|uniprotkb:Q9CX89|intact:MINT-4616110|uniprotkb:Q9DB99|uniprotkb:Q921D3|ensembl:ENSMUSP00000030791 psi-mi:notc1_mouse(display_long)|uniprotkb:Notch1(gene name)|psi-mi:Notch1(display_short)|uniprotkb:Motch(gene name synonym)|uniprotkb:Motch A(gene name synonym)|uniprotkb:p300(gene name synonym)|uniprotkb:mT14(gene name synonym) psi-mi:smrd3_mouse(display_long)|uniprotkb:Smarcd3(gene name)|psi-mi:Smarcd3(display_short)|uniprotkb:Baf60c(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15618129|imex:IM-22495-3|dip:DIP-196272E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032740.3|dip:DIP-214N|ensembl:ENSMUSG00000026923(gene)|ensembl:ENSMUST00000028288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003264"(regulation of cardioblast proliferation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1YMP|rcsb pdb:2QC9|rcsb pdb:2RQZ|rcsb pdb:2RR0|rcsb pdb:2RR2|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:5KY0|rcsb pdb:5KY4|rcsb pdb:5KY8|rcsb pdb:5KY9|reactome:R-MMU-1912420|reactome:R-MMU-2122947|reactome:R-MMU-2122948|reactome:R-MMU-350054|reactome:R-MMU-8941856 refseq:NP_080167.3|ensembl:ENSMUSG00000028949(gene)|ensembl:ENSMUST00000030791(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|reactome:R-MMU-3214858|reactome:R-MMU-400206|reactome:R-MMU-8939243|reactome:R-MMU-9707564|dip:DIP-48886N psi-mi:"MI:0465"(dip) - comment:mint|comment:homomint|function:Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:VOWlSJ0z/YkR4qWQ6MHjD/CVitg10090 rogid:5BEcU8cyfZR0UDJLvhsMwr9p18w10090 rigid:m6YZj4Nvpxs8TDV3dsVB+rNTJWI false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01705 uniprotkb:Q3TKT4 intact:EBI-1392707|uniprotkb:Q06007|uniprotkb:Q61905|uniprotkb:Q99JC2|uniprotkb:Q9QW58|uniprotkb:Q9R0X7|uniprotkb:Q3TZW2|uniprotkb:Q3U3Y2|uniprotkb:Q7TQ50|uniprotkb:Q7TQ51|uniprotkb:Q7TQ52|uniprotkb:Q8K428|ensembl:ENSMUSP00000028288 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:notc1_mouse(display_long)|uniprotkb:Notch1(gene name)|psi-mi:Notch1(display_short)|uniprotkb:Motch(gene name synonym)|uniprotkb:Motch A(gene name synonym)|uniprotkb:p300(gene name synonym)|uniprotkb:mT14(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15618129|imex:IM-22495-3|dip:DIP-196272E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032740.3|dip:DIP-214N|ensembl:ENSMUSG00000026923(gene)|ensembl:ENSMUST00000028288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003264"(regulation of cardioblast proliferation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1YMP|rcsb pdb:2QC9|rcsb pdb:2RQZ|rcsb pdb:2RR0|rcsb pdb:2RR2|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:5KY0|rcsb pdb:5KY4|rcsb pdb:5KY8|rcsb pdb:5KY9|reactome:R-MMU-1912420|reactome:R-MMU-2122947|reactome:R-MMU-2122948|reactome:R-MMU-350054|reactome:R-MMU-8941856 refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:VOWlSJ0z/YkR4qWQ6MHjD/CVitg10090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:m6YZj4Nvpxs8TDV3dsVB+rNTJWI false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q6P9Z1 uniprotkb:P31266 intact:EBI-7525857|uniprotkb:Q9CX89|intact:MINT-4616110|uniprotkb:Q9DB99|uniprotkb:Q921D3|ensembl:ENSMUSP00000030791 intact:EBI-1392666|uniprotkb:Q80UN8|uniprotkb:Q8C4Z3|ensembl:ENSMUSP00000040694 psi-mi:smrd3_mouse(display_long)|uniprotkb:Smarcd3(gene name)|psi-mi:Smarcd3(display_short)|uniprotkb:Baf60c(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:suh_mouse(display_long)|uniprotkb:Rbpj(gene name)|psi-mi:Rbpj(display_short)|uniprotkb:Igkjrb1(gene name synonym)|uniprotkb:Igkrsbp(gene name synonym)|uniprotkb:Rbpsuh(gene name synonym)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym) psi-mi:"MI:0096"(pull down) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15618149|imex:IM-22495-4|dip:DIP-196268E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080167.3|ensembl:ENSMUSG00000028949(gene)|ensembl:ENSMUST00000030791(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|reactome:R-MMU-3214858|reactome:R-MMU-400206|reactome:R-MMU-8939243|reactome:R-MMU-9707564|dip:DIP-48886N refseq:NP_001074396.1|refseq:NP_033061.3|dip:DIP-171N|ensembl:ENSMUSG00000039191(gene)|ensembl:ENSMUST00000037618(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001947"(heart looping)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|rcsb pdb:3BRG|rcsb pdb:3IAG|rcsb pdb:4J2X|rcsb pdb:5EG6|rcsb pdb:6DKS|rcsb pdb:6WQU|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856 psi-mi:"MI:0465"(dip) comment:mint|comment:homomint|function:Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:5BEcU8cyfZR0UDJLvhsMwr9p18w10090 rogid:6e2XZZX+zWA0UexPo1D0+3Hv08Y10090 rigid:3m+p9djY7fRtrceztetCsDNHw8Y false tag:n-n 35s radiolabel:?-? - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:P31266 uniprotkb:Q6P9Z1 intact:EBI-1392666|uniprotkb:Q80UN8|uniprotkb:Q8C4Z3|ensembl:ENSMUSP00000040694 intact:EBI-7525857|uniprotkb:Q9CX89|intact:MINT-4616110|uniprotkb:Q9DB99|uniprotkb:Q921D3|ensembl:ENSMUSP00000030791 psi-mi:suh_mouse(display_long)|uniprotkb:Rbpj(gene name)|psi-mi:Rbpj(display_short)|uniprotkb:Igkjrb1(gene name synonym)|uniprotkb:Igkrsbp(gene name synonym)|uniprotkb:Rbpsuh(gene name synonym)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym) psi-mi:smrd3_mouse(display_long)|uniprotkb:Smarcd3(gene name)|psi-mi:Smarcd3(display_short)|uniprotkb:Baf60c(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15618170|imex:IM-22495-5|dip:DIP-196271E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001074396.1|refseq:NP_033061.3|dip:DIP-171N|ensembl:ENSMUSG00000039191(gene)|ensembl:ENSMUST00000037618(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001947"(heart looping)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|rcsb pdb:3BRG|rcsb pdb:3IAG|rcsb pdb:4J2X|rcsb pdb:5EG6|rcsb pdb:6DKS|rcsb pdb:6WQU|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856 refseq:NP_080167.3|ensembl:ENSMUSG00000028949(gene)|ensembl:ENSMUST00000030791(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|reactome:R-MMU-3214858|reactome:R-MMU-400206|reactome:R-MMU-8939243|reactome:R-MMU-9707564|dip:DIP-48886N psi-mi:"MI:0465"(dip) - comment:mint|comment:homomint|function:Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:6e2XZZX+zWA0UexPo1D0+3Hv08Y10090 rogid:5BEcU8cyfZR0UDJLvhsMwr9p18w10090 rigid:jrmo2GNuGwS8JlvmwFa+amHKo+g false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P31266 uniprotkb:Q3TKT4 intact:EBI-1392666|uniprotkb:Q80UN8|uniprotkb:Q8C4Z3|ensembl:ENSMUSP00000040694 intact:EBI-1210244|uniprotkb:Q6AXG8|uniprotkb:Q3TUD7|ensembl:ENSMUSP00000133922 psi-mi:suh_mouse(display_long)|uniprotkb:Rbpj(gene name)|psi-mi:Rbpj(display_short)|uniprotkb:Igkjrb1(gene name synonym)|uniprotkb:Igkrsbp(gene name synonym)|uniprotkb:Rbpsuh(gene name synonym)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym) psi-mi:smca4_mouse(display_long)|uniprotkb:Smarca4(gene name)|psi-mi:Smarca4(display_short)|uniprotkb:Baf190a(gene name synonym)|uniprotkb:Brg1(gene name synonym)|uniprotkb:Snf2b(gene name synonym)|uniprotkb:Snf2l4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15618170|imex:IM-22495-5|dip:DIP-196271E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001074396.1|refseq:NP_033061.3|dip:DIP-171N|ensembl:ENSMUSG00000039191(gene)|ensembl:ENSMUST00000037618(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001947"(heart looping)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|rcsb pdb:3BRG|rcsb pdb:3IAG|rcsb pdb:4J2X|rcsb pdb:5EG6|rcsb pdb:6DKS|rcsb pdb:6WQU|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856 refseq:NP_001167549.1|refseq:NP_001167550.1|refseq:NP_035547.2|refseq:XP_006510180.2|refseq:XP_006510182.2|refseq:XP_006510183.2|dip:DIP-40650N|dip:DIP-59249N|ensembl:ENSMUSG00000032187(gene)|ensembl:ENSMUST00000174008(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001568"(blood vessel development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0001889"(liver development)|go:"GO:0002039"(p53 binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007399"(nervous system development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007507"(heart development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0010467"(gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030957"(Tat protein binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035887"(aortic smooth muscle cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048562"(embryonic organ morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060318"(definitive erythrocyte differentiation)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR038718|mint:Q3TKT4|reactome:R-MMU-1266695|reactome:R-MMU-201722|reactome:R-MMU-3214858|reactome:R-MMU-3247509|reactome:R-MMU-8939243|interpro:IPR037259 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:6e2XZZX+zWA0UexPo1D0+3Hv08Y10090 rogid:uLQrygmWWugY//OpA2aX4t2VgmM10090 rigid:jrmo2GNuGwS8JlvmwFa+amHKo+g false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P70326 uniprotkb:Q6P9Z1 intact:EBI-8411807|uniprotkb:Q9R003|intact:MINT-4137187|ensembl:ENSMUSP00000018407 intact:EBI-7525857|uniprotkb:Q9CX89|intact:MINT-4616110|uniprotkb:Q9DB99|uniprotkb:Q921D3|ensembl:ENSMUSP00000030791 psi-mi:tbx5_mouse(display_long)|uniprotkb:Tbx5(gene name)|psi-mi:Tbx5(display_short) psi-mi:smrd3_mouse(display_long)|uniprotkb:Smarcd3(gene name)|psi-mi:Smarcd3(display_short)|uniprotkb:Baf60c(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0096"(pull down) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15618190|imex:IM-22495-6|dip:DIP-196269E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011246493.1|refseq:NP_035667.1|refseq:XP_006530343.1|refseq:XP_006530344.1|refseq:XP_006530345.1|refseq:XP_006530346.1|refseq:XP_017176276.1|dip:DIP-48887N|ensembl:ENSMUSG00000018263(gene)|ensembl:ENSMUST00000018407(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003166"(bundle of His development)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003218"(cardiac left ventricle formation)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003283"(atrial septum development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007389"(pattern specification process)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048513"(animal organ development)|go:"GO:0051891"(positive regulation of cardioblast differentiation)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060039"(pericardium development)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060290"(transdifferentiation)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060928"(atrioventricular node cell development)|go:"GO:0060929"(atrioventricular node cell fate commitment)|go:"GO:0072513"(positive regulation of secondary heart field cardioblast proliferation)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086054"(bundle of His cell to Purkinje myocyte communication by electrical coupling)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903781"(positive regulation of cardiac conduction)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR036960|mint:P70326|rcsb pdb:5FLV|reactome:R-MMU-2032785 refseq:NP_080167.3|ensembl:ENSMUSG00000028949(gene)|ensembl:ENSMUST00000030791(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|reactome:R-MMU-3214858|reactome:R-MMU-400206|reactome:R-MMU-8939243|reactome:R-MMU-9707564|dip:DIP-48886N psi-mi:"MI:0465"(dip) function:Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation|comment:mint comment:mint|comment:homomint|function:Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:i1XrRIxNM++VvPUapK4t789c+f410090 rogid:5BEcU8cyfZR0UDJLvhsMwr9p18w10090 rigid:vE9rgTvnx74pipM7OG76JUGDVEU false 35s radiolabel:?-? tag:n-n - - psi-mi:"MI:0833"(autoradiography) psi-mi:"MI:0833"(autoradiography) uniprotkb:Q6P9Z1 uniprotkb:Q01705 intact:EBI-7525857|uniprotkb:Q9CX89|intact:MINT-4616110|uniprotkb:Q9DB99|uniprotkb:Q921D3|ensembl:ENSMUSP00000030791 intact:EBI-1392707|uniprotkb:Q06007|uniprotkb:Q61905|uniprotkb:Q99JC2|uniprotkb:Q9QW58|uniprotkb:Q9R0X7|uniprotkb:Q3TZW2|uniprotkb:Q3U3Y2|uniprotkb:Q7TQ50|uniprotkb:Q7TQ51|uniprotkb:Q7TQ52|uniprotkb:Q8K428|ensembl:ENSMUSP00000028288 psi-mi:smrd3_mouse(display_long)|uniprotkb:Smarcd3(gene name)|psi-mi:Smarcd3(display_short)|uniprotkb:Baf60c(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:notc1_mouse(display_long)|uniprotkb:Notch1(gene name)|psi-mi:Notch1(display_short)|uniprotkb:Motch(gene name synonym)|uniprotkb:Motch A(gene name synonym)|uniprotkb:p300(gene name synonym)|uniprotkb:mT14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15618211|imex:IM-22495-7|dip:DIP-196273E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_080167.3|ensembl:ENSMUSG00000028949(gene)|ensembl:ENSMUST00000030791(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|reactome:R-MMU-3214858|reactome:R-MMU-400206|reactome:R-MMU-8939243|reactome:R-MMU-9707564|dip:DIP-48886N refseq:NP_032740.3|dip:DIP-214N|ensembl:ENSMUSG00000026923(gene)|ensembl:ENSMUST00000028288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003264"(regulation of cardioblast proliferation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1YMP|rcsb pdb:2QC9|rcsb pdb:2RQZ|rcsb pdb:2RR0|rcsb pdb:2RR2|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:5KY0|rcsb pdb:5KY4|rcsb pdb:5KY8|rcsb pdb:5KY9|reactome:R-MMU-1912420|reactome:R-MMU-2122947|reactome:R-MMU-2122948|reactome:R-MMU-350054|reactome:R-MMU-8941856 psi-mi:"MI:0465"(dip) comment:mint|comment:homomint|function:Plays a role in ATP dependent nucleosome remodeling by SMARCA4 containing complexes. Stimulates nuclear receptor mediated transcription - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:5BEcU8cyfZR0UDJLvhsMwr9p18w10090 rogid:VOWlSJ0z/YkR4qWQ6MHjD/CVitg10090 rigid:0Ta/JPk+odqTBZpPuECWUd6nHho false - myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P31266 uniprotkb:Q01705 intact:EBI-1392666|uniprotkb:Q80UN8|uniprotkb:Q8C4Z3|ensembl:ENSMUSP00000040694 intact:EBI-1392707|uniprotkb:Q06007|uniprotkb:Q61905|uniprotkb:Q99JC2|uniprotkb:Q9QW58|uniprotkb:Q9R0X7|uniprotkb:Q3TZW2|uniprotkb:Q3U3Y2|uniprotkb:Q7TQ50|uniprotkb:Q7TQ51|uniprotkb:Q7TQ52|uniprotkb:Q8K428|ensembl:ENSMUSP00000028288 psi-mi:suh_mouse(display_long)|uniprotkb:Rbpj(gene name)|psi-mi:Rbpj(display_short)|uniprotkb:Igkjrb1(gene name synonym)|uniprotkb:Igkrsbp(gene name synonym)|uniprotkb:Rbpsuh(gene name synonym)|uniprotkb:J kappa-recombination signal-binding protein(gene name synonym)|uniprotkb:RBP-J kappa(gene name synonym) psi-mi:notc1_mouse(display_long)|uniprotkb:Notch1(gene name)|psi-mi:Notch1(display_short)|uniprotkb:Motch(gene name synonym)|uniprotkb:Motch A(gene name synonym)|uniprotkb:p300(gene name synonym)|uniprotkb:mT14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Takeuchi et al. (2007) pubmed:17210915|doi:10.1073/pnas.0608118104|imex:IM-22495 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15618230|imex:IM-22495-8|dip:DIP-698E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001074396.1|refseq:NP_033061.3|dip:DIP-171N|ensembl:ENSMUSG00000039191(gene)|ensembl:ENSMUST00000037618(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001756"(somitogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001947"(heart looping)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009957"(epidermal cell fate specification)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034392"(negative regulation of smooth muscle cell apoptotic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035481"(positive regulation of Notch signaling pathway involved in heart induction)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048505"(regulation of timing of cell differentiation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048733"(sebaceous gland development)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0060844"(arterial endothelial cell fate commitment)|go:"GO:0060853"(Notch signaling pathway involved in arterial endothelial cell fate commitment)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061371"(determination of heart left/right asymmetry)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072554"(blood vessel lumenization)|go:"GO:0097101"(blood vessel endothelial cell fate specification)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901186"(positive regulation of ERBB signaling pathway)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901297"(positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR015350(Beta-trefoil)|interpro:IPR015351(LAG1, DNA binding)|interpro:IPR036358|interpro:IPR037095|interpro:IPR038007|interpro:IPR040159|rcsb pdb:3BRG|rcsb pdb:3IAG|rcsb pdb:4J2X|rcsb pdb:5EG6|rcsb pdb:6DKS|rcsb pdb:6WQU|reactome:R-MMU-2122947|reactome:R-MMU-350054|reactome:R-MMU-8941856 refseq:NP_032740.3|dip:DIP-214N|ensembl:ENSMUSG00000026923(gene)|ensembl:ENSMUST00000028288(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003264"(regulation of cardioblast proliferation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008544"(epidermis development)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045607"(regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1901189"(positive regulation of ephrin receptor signaling pathway)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|rcsb pdb:1YMP|rcsb pdb:2QC9|rcsb pdb:2RQZ|rcsb pdb:2RR0|rcsb pdb:2RR2|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:5KY0|rcsb pdb:5KY4|rcsb pdb:5KY8|rcsb pdb:5KY9|reactome:R-MMU-1912420|reactome:R-MMU-2122947|reactome:R-MMU-2122948|reactome:R-MMU-350054|reactome:R-MMU-8941856 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse)|taxid:10090(Mus musculus) - 2017/08/05 2017/08/10 rogid:6e2XZZX+zWA0UexPo1D0+3Hv08Y10090 rogid:VOWlSJ0z/YkR4qWQ6MHjD/CVitg10090 rigid:IkNaG3nNHoNQjDQdV2ReqZ50jSY false flag tag:n-n myc tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)