#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P51795 uniprotkb:P51795 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Meyer et al. (2007) pubmed:17195847|doi:10.1038/nsmb1188|imex:IM-8609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15617611|imex:IM-8609-2|dip:DIP-57290E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2020/08/15 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rigid:9Ub4EEWaxI27qV21QIVuI0DGuAA false sufficient binding region:638-816 sufficient binding region:638-816 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51795 uniprotkb:P51795 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 intact:EBI-13619183|ensembl:ENSP00000365256|ensembl:ENSP00000365259|uniprotkb:A1L475|uniprotkb:B3KPN6|uniprotkb:Q5JQD5|uniprotkb:Q7RTN8 psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:clcn5_human(display_long)|uniprotkb:CLCN5(gene name)|psi-mi:CLCN5(display_short)|uniprotkb:CLCK2(gene name synonym)|uniprotkb:Chloride channel protein 5(gene name synonym)|uniprotkb:Chloride transporter ClC-5(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Meyer et al. (2007) pubmed:17195847|doi:10.1038/nsmb1188|imex:IM-8609 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15617629|imex:IM-8609-1|dip:DIP-57290E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N ensembl:ENSG00000171365(gene)|ensembl:ENST00000376088(transcript)|ensembl:ENST00000376091(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005247"(voltage-gated chloride channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007588"(excretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0015297"(antiporter activity)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001807(Chloride channel, voltage gated)|interpro:IPR002247(Chloride channel CLC-5)|interpro:IPR014743(Chloride channel, core)|rcsb pdb:2J9L|rcsb pdb:2JA3|reactome:R-HSA-2672351|refseq:NP_000075.1|refseq:NP_001121370.1|refseq:NP_001121371.1|refseq:NP_001269092.1|dip:DIP-29263N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human)|taxid:9606(Homo sapiens) - 2017/08/05 2020/08/15 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rogid:8f3zMSNelJ4fxwOH6jiOgfNrhQc9606 rigid:9Ub4EEWaxI27qV21QIVuI0DGuAA false sufficient binding region:638-816 sufficient binding region:638-816 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)