#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P45381	uniprotkb:P45381	intact:EBI-750475|ensembl:ENSP00000263080|ensembl:ENSP00000409976	intact:EBI-750475|ensembl:ENSP00000263080|ensembl:ENSP00000409976	psi-mi:acy2_human(display_long)|uniprotkb:Aminoacylase-2(gene name synonym)|uniprotkb:ASPA(gene name)|psi-mi:ASPA(display_short)|uniprotkb:ACY2(gene name synonym)|uniprotkb:ASP(gene name synonym)	psi-mi:acy2_human(display_long)|uniprotkb:Aminoacylase-2(gene name synonym)|uniprotkb:ASPA(gene name)|psi-mi:ASPA(display_short)|uniprotkb:ACY2(gene name synonym)|uniprotkb:ASP(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Bitto et al. (2007)	pubmed:17194761|doi:10.1073/pnas.0607817104|imex:IM-22490	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15617520|imex:IM-22490-1|dip:DIP-196261E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000040.1|refseq:NP_001121557.1|refseq:XP_016880150.1|dip:DIP-60793N|ensembl:ENSG00000108381(gene)|ensembl:ENST00000263080(transcript)|ensembl:ENST00000456349(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|rcsb pdb:2I3C|rcsb pdb:2O4H|rcsb pdb:2O53|rcsb pdb:2Q51|rcsb pdb:4MRI|rcsb pdb:4MXU|rcsb pdb:4NFR|rcsb pdb:4TNU|reactome:R-HSA-8963693|go:"GO:0046872"(metal ion binding)	refseq:NP_000040.1|refseq:NP_001121557.1|refseq:XP_016880150.1|dip:DIP-60793N|ensembl:ENSG00000108381(gene)|ensembl:ENST00000263080(transcript)|ensembl:ENST00000456349(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|rcsb pdb:2I3C|rcsb pdb:2O4H|rcsb pdb:2O53|rcsb pdb:2Q51|rcsb pdb:4MRI|rcsb pdb:4MXU|rcsb pdb:4NFR|rcsb pdb:4TNU|reactome:R-HSA-8963693|go:"GO:0046872"(metal ion binding)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:vUfRUzCdS988Z3lmexnAMPr7+5Q9606	rogid:vUfRUzCdS988Z3lmexnAMPr7+5Q9606	rigid:0TB5lmikdT6C6A5QwHQMEsKqpUs	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R1T5	uniprotkb:Q9R1T5	intact:EBI-15617537|ensembl:ENSRNOP00000072876|ensembl:ENSRNOP00000076091|uniprotkb:Q6AZ03	intact:EBI-15617537|ensembl:ENSRNOP00000072876|ensembl:ENSRNOP00000076091|uniprotkb:Q6AZ03	psi-mi:acy2_rat(display_long)|uniprotkb:Aspa(gene name)|psi-mi:Aspa(display_short)|uniprotkb:Aminoacylase-2(gene name synonym)	psi-mi:acy2_rat(display_long)|uniprotkb:Aspa(gene name)|psi-mi:Aspa(display_short)|uniprotkb:Aminoacylase-2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Bitto et al. (2007)	pubmed:17194761|doi:10.1073/pnas.0607817104|imex:IM-22490	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15617568|imex:IM-22490-2|dip:DIP-196262E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000019659(gene)|ensembl:ENSRNOT00000084432(transcript)|ensembl:ENSRNOT00000093230(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|rcsb pdb:2GU2|rcsb pdb:2Q4Z|reactome:R-RNO-8963693|refseq:NP_077375.1|refseq:XP_006246877.1|rgd:621693|dip:DIP-60794N	ensembl:ENSRNOG00000019659(gene)|ensembl:ENSRNOT00000084432(transcript)|ensembl:ENSRNOT00000093230(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|rcsb pdb:2GU2|rcsb pdb:2Q4Z|reactome:R-RNO-8963693|refseq:NP_077375.1|refseq:XP_006246877.1|rgd:621693|dip:DIP-60794N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:Bo2f8R685iMeClO0m78kfvkf+b810116	rogid:Bo2f8R685iMeClO0m78kfvkf+b810116	rigid:T8QgbHYHqbME7tyRr1uSDtFgYaI	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9R1T5	uniprotkb:Q9R1T5	intact:EBI-15617537|ensembl:ENSRNOP00000072876|ensembl:ENSRNOP00000076091|uniprotkb:Q6AZ03	intact:EBI-15617537|ensembl:ENSRNOP00000072876|ensembl:ENSRNOP00000076091|uniprotkb:Q6AZ03	psi-mi:acy2_rat(display_long)|uniprotkb:Aspa(gene name)|psi-mi:Aspa(display_short)|uniprotkb:Aminoacylase-2(gene name synonym)	psi-mi:acy2_rat(display_long)|uniprotkb:Aspa(gene name)|psi-mi:Aspa(display_short)|uniprotkb:Aminoacylase-2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Bitto et al. (2007)	pubmed:17194761|doi:10.1073/pnas.0607817104|imex:IM-22490	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15617584|imex:IM-22490-3|dip:DIP-196262E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000019659(gene)|ensembl:ENSRNOT00000084432(transcript)|ensembl:ENSRNOT00000093230(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|rcsb pdb:2GU2|rcsb pdb:2Q4Z|reactome:R-RNO-8963693|refseq:NP_077375.1|refseq:XP_006246877.1|rgd:621693|dip:DIP-60794N	ensembl:ENSRNOG00000019659(gene)|ensembl:ENSRNOT00000084432(transcript)|ensembl:ENSRNOT00000093230(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|rcsb pdb:2GU2|rcsb pdb:2Q4Z|reactome:R-RNO-8963693|refseq:NP_077375.1|refseq:XP_006246877.1|rgd:621693|dip:DIP-60794N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:Bo2f8R685iMeClO0m78kfvkf+b810116	rogid:Bo2f8R685iMeClO0m78kfvkf+b810116	rigid:T8QgbHYHqbME7tyRr1uSDtFgYaI	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)