#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P47027 uniprotkb:P34252 intact:EBI-25984|uniprotkb:Q05712|uniprotkb:D6VW94|ensemblfungi:YJL090C intact:EBI-26824|uniprotkb:D6VXH9|ensemblfungi:YKL108W psi-mi:dpb11_yeast(display_long)|uniprotkb:DPB11(gene name)|psi-mi:DPB11(display_short)|uniprotkb:J0918(orf name)|uniprotkb:YJL090C(locus name) psi-mi:sld2_yeast(display_long)|uniprotkb:SLD2(gene name)|psi-mi:SLD2(display_short)|uniprotkb:DRC1(gene name synonym)|uniprotkb:YKL108W(locus name)|uniprotkb:YKL463(orf name)|uniprotkb:DNA replication and checkpoint protein 1(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Zegerman et al. (2007) pubmed:17167417|doi:10.1038/nature05432|imex:IM-21188 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15615527|imex:IM-21188-1|dip:DIP-10478E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003626|refseq:NP_012445.1|dip:DIP-5037N|ensemblfungi:YJL090C(gene)|ensemblfungi:YJL090C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007533"(mating type switching)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1902597"(positive regulation of DNA replication origin binding)|interpro:IPR001357(BRCT)|interpro:IPR036420 refseq:NP_012814.1|sgd:S000001591|mint:P34252|dip:DIP-5880N|ensemblfungi:YKL108W(gene)|ensemblfungi:YKL108W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR021110|interpro:IPR040203 psi-mi:"MI:0465"(dip) crc64:79B3A9BC7815E440 crc64:52B2969C97AAEAC8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:CYn2Q78DOL/+HPutAsKRuKofolE559292 rogid:j3IuqY8BjP4/m8b65FJtpVnOREw559292 rigid:IfwZgBiAKMFvfv2BftHDwUMrdfI false sufficient binding region:248-764 O-phospho-L-threonine:84-84|sufficient binding region:61-110 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47027 uniprotkb:P34252 intact:EBI-25984|uniprotkb:Q05712|uniprotkb:D6VW94|ensemblfungi:YJL090C intact:EBI-26824|uniprotkb:D6VXH9|ensemblfungi:YKL108W psi-mi:dpb11_yeast(display_long)|uniprotkb:DPB11(gene name)|psi-mi:DPB11(display_short)|uniprotkb:J0918(orf name)|uniprotkb:YJL090C(locus name) psi-mi:sld2_yeast(display_long)|uniprotkb:SLD2(gene name)|psi-mi:SLD2(display_short)|uniprotkb:DRC1(gene name synonym)|uniprotkb:YKL108W(locus name)|uniprotkb:YKL463(orf name)|uniprotkb:DNA replication and checkpoint protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Zegerman et al. (2007) pubmed:17167417|doi:10.1038/nature05432|imex:IM-21188 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15615551|imex:IM-21188-2|dip:DIP-10478E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003626|refseq:NP_012445.1|dip:DIP-5037N|ensemblfungi:YJL090C(gene)|ensemblfungi:YJL090C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007533"(mating type switching)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1902597"(positive regulation of DNA replication origin binding)|interpro:IPR001357(BRCT)|interpro:IPR036420 refseq:NP_012814.1|sgd:S000001591|mint:P34252|dip:DIP-5880N|ensemblfungi:YKL108W(gene)|ensemblfungi:YKL108W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0071163"(DNA replication preinitiation complex assembly)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR021110|interpro:IPR040203 psi-mi:"MI:0465"(dip) crc64:79B3A9BC7815E440 crc64:52B2969C97AAEAC8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:CYn2Q78DOL/+HPutAsKRuKofolE559292 rogid:j3IuqY8BjP4/m8b65FJtpVnOREw559292 rigid:IfwZgBiAKMFvfv2BftHDwUMrdfI false glutathione s tranferase tag:c-c O-phospho-L-threonine:84-84|sufficient binding region:61-110|biotin tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P47027 uniprotkb:P53135 intact:EBI-25984|uniprotkb:Q05712|uniprotkb:D6VW94|ensemblfungi:YJL090C intact:EBI-23925|uniprotkb:D6VU34|ensemblfungi:YGL113W psi-mi:dpb11_yeast(display_long)|uniprotkb:DPB11(gene name)|psi-mi:DPB11(display_short)|uniprotkb:J0918(orf name)|uniprotkb:YJL090C(locus name) psi-mi:sld3_yeast(display_long)|uniprotkb:SLD3(gene name)|psi-mi:SLD3(display_short)|uniprotkb:G2980(orf name)|uniprotkb:YGL113W(locus name) psi-mi:"MI:0107"(surface plasmon resonance) Zegerman et al. (2007) pubmed:17167417|doi:10.1038/nature05432|imex:IM-21188 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15615578|imex:IM-21188-3|dip:DIP-187422E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003626|refseq:NP_012445.1|dip:DIP-5037N|ensemblfungi:YJL090C(gene)|ensemblfungi:YJL090C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007533"(mating type switching)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1902597"(positive regulation of DNA replication origin binding)|interpro:IPR001357(BRCT)|interpro:IPR036420 sgd:S000003081|refseq:NP_011402.3|dip:DIP-5481N|mint:P53135|ensemblfungi:YGL113W(gene)|ensemblfungi:YGL113W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR013948(DNA replication regulator Sld3)|interpro:IPR041393|interpro:IPR042511|rcsb pdb:3WI3 psi-mi:"MI:0465"(dip) crc64:79B3A9BC7815E440 crc64:6E59D0DB3C082C28 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:CYn2Q78DOL/+HPutAsKRuKofolE559292 rogid:1uxenWX3lYYMDUWr0mAE207XsHI559292 rigid:qAs64ZNbIttjeGQqTIH4VT+iG9E false sufficient binding region:1-395|mutation disrupting interaction strength:56-56,55-55 O-phospho-L-threonine:609-609,600-600|O-phospho-L-serine:622-622|sufficient binding region:590-639 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P47027 uniprotkb:P53135 intact:EBI-25984|uniprotkb:Q05712|uniprotkb:D6VW94|ensemblfungi:YJL090C intact:EBI-23925|uniprotkb:D6VU34|ensemblfungi:YGL113W psi-mi:dpb11_yeast(display_long)|uniprotkb:DPB11(gene name)|psi-mi:DPB11(display_short)|uniprotkb:J0918(orf name)|uniprotkb:YJL090C(locus name) psi-mi:sld3_yeast(display_long)|uniprotkb:SLD3(gene name)|psi-mi:SLD3(display_short)|uniprotkb:G2980(orf name)|uniprotkb:YGL113W(locus name) psi-mi:"MI:0096"(pull down) Zegerman et al. (2007) pubmed:17167417|doi:10.1038/nature05432|imex:IM-21188 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15615610|imex:IM-21188-4|dip:DIP-187422E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003626|refseq:NP_012445.1|dip:DIP-5037N|ensemblfungi:YJL090C(gene)|ensemblfungi:YJL090C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007533"(mating type switching)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1902597"(positive regulation of DNA replication origin binding)|interpro:IPR001357(BRCT)|interpro:IPR036420 sgd:S000003081|refseq:NP_011402.3|dip:DIP-5481N|mint:P53135|ensemblfungi:YGL113W(gene)|ensemblfungi:YGL113W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR013948(DNA replication regulator Sld3)|interpro:IPR041393|interpro:IPR042511|rcsb pdb:3WI3 psi-mi:"MI:0465"(dip) crc64:79B3A9BC7815E440 crc64:6E59D0DB3C082C28 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:CYn2Q78DOL/+HPutAsKRuKofolE559292 rogid:1uxenWX3lYYMDUWr0mAE207XsHI559292 rigid:qAs64ZNbIttjeGQqTIH4VT+iG9E false glutathione s tranferase tag:c-c O-phospho-L-threonine:600-600|O-phospho-L-serine:622-622|sufficient binding region:590-639|biotin tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)