#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q08032	uniprotkb:P53135	intact:EBI-4292|uniprotkb:Q05908|uniprotkb:D6VYA3|ensemblfungi:YLR103C	intact:EBI-23925|uniprotkb:D6VU34|ensemblfungi:YGL113W	psi-mi:cdc45_yeast(display_long)|uniprotkb:CDC45(gene name)|psi-mi:CDC45(display_short)|uniprotkb:YLR103C(locus name)|uniprotkb:L8004.11(orf name)|uniprotkb:SLD4(gene name synonym)	psi-mi:sld3_yeast(display_long)|uniprotkb:SLD3(gene name)|psi-mi:SLD3(display_short)|uniprotkb:G2980(orf name)|uniprotkb:YGL113W(locus name)	psi-mi:"MI:0018"(two hybrid)	Tanaka et al. (2007)	pubmed:17167415|doi:10.1038/nature05465|imex:IM-21187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15615389|imex:IM-21187-1|dip:DIP-187424E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013204.1|sgd:S000004093|dip:DIP-2405N|mint:Q08032|ensemblfungi:YLR103C(gene)|ensemblfungi:YLR103C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-68962	sgd:S000003081|refseq:NP_011402.3|dip:DIP-5481N|mint:P53135|ensemblfungi:YGL113W(gene)|ensemblfungi:YGL113W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR013948(DNA replication regulator Sld3)|interpro:IPR041393|interpro:IPR042511|rcsb pdb:3WI3	psi-mi:"MI:0465"(dip)	crc64:6500DDD62EC4E8EE	crc64:6E59D0DB3C082C28	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:ErMEWxRKsJsPBDo5EfTfBL57hAY559292	rogid:1uxenWX3lYYMDUWr0mAE207XsHI559292	rigid:uw4fgpDwG3RC5ozWdAdZjE0hM8g	false	-	sufficient binding region:1-548	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P47027	uniprotkb:P53135	intact:EBI-25984|uniprotkb:Q05712|uniprotkb:D6VW94|ensemblfungi:YJL090C	intact:EBI-23925|uniprotkb:D6VU34|ensemblfungi:YGL113W	psi-mi:dpb11_yeast(display_long)|uniprotkb:DPB11(gene name)|psi-mi:DPB11(display_short)|uniprotkb:J0918(orf name)|uniprotkb:YJL090C(locus name)	psi-mi:sld3_yeast(display_long)|uniprotkb:SLD3(gene name)|psi-mi:SLD3(display_short)|uniprotkb:G2980(orf name)|uniprotkb:YGL113W(locus name)	psi-mi:"MI:0018"(two hybrid)	Tanaka et al. (2007)	pubmed:17167415|doi:10.1038/nature05465|imex:IM-21187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15615427|imex:IM-21187-3|dip:DIP-187422E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003626|refseq:NP_012445.1|dip:DIP-5037N|ensemblfungi:YJL090C(gene)|ensemblfungi:YJL090C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007533"(mating type switching)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1902597"(positive regulation of DNA replication origin binding)|interpro:IPR001357(BRCT)|interpro:IPR036420	sgd:S000003081|refseq:NP_011402.3|dip:DIP-5481N|mint:P53135|ensemblfungi:YGL113W(gene)|ensemblfungi:YGL113W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR013948(DNA replication regulator Sld3)|interpro:IPR041393|interpro:IPR042511|rcsb pdb:3WI3	psi-mi:"MI:0465"(dip)	crc64:79B3A9BC7815E440	crc64:6E59D0DB3C082C28	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:CYn2Q78DOL/+HPutAsKRuKofolE559292	rogid:1uxenWX3lYYMDUWr0mAE207XsHI559292	rigid:qAs64ZNbIttjeGQqTIH4VT+iG9E	false	sufficient binding region:1-309	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08032	uniprotkb:Q12146	intact:EBI-4292|uniprotkb:Q05908|uniprotkb:D6VYA3|ensemblfungi:YLR103C	intact:EBI-30392|uniprotkb:D6W1S3|ensemblfungi:YOL146W	psi-mi:cdc45_yeast(display_long)|uniprotkb:CDC45(gene name)|psi-mi:CDC45(display_short)|uniprotkb:YLR103C(locus name)|uniprotkb:L8004.11(orf name)|uniprotkb:SLD4(gene name synonym)	psi-mi:psf3_yeast(display_long)|uniprotkb:YOL146W(locus name)|uniprotkb:Partner of Sld five 3(gene name synonym)|uniprotkb:PSF3(gene name)|psi-mi:PSF3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tanaka et al. (2007)	pubmed:17167415|doi:10.1038/nature05465|imex:IM-21187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15615446|imex:IM-21187-4|dip:DIP-191083E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013204.1|sgd:S000004093|dip:DIP-2405N|mint:Q08032|ensemblfungi:YLR103C(gene)|ensemblfungi:YLR103C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-68962	refseq:NP_014495.2|sgd:S000005506|dip:DIP-4461N|mint:Q12146|ensemblfungi:YOL146W(gene)|ensemblfungi:YOL146W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974	psi-mi:"MI:0465"(dip)	crc64:6500DDD62EC4E8EE	crc64:3E8B60DFCE16391D	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:ErMEWxRKsJsPBDo5EfTfBL57hAY559292	rogid:wPLgebaZqVSf/ym9bOxp++xENeA559292	rigid:beV3wZskX3rfCwQBiD906kELmR4	false	mutation increasing interaction strength:22-22|flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08032	uniprotkb:Q03406	intact:EBI-4292|uniprotkb:Q05908|uniprotkb:D6VYA3|ensemblfungi:YLR103C	intact:EBI-37437|uniprotkb:Q6Q558|uniprotkb:D6VTB2|ensemblfungi:YDR489W	psi-mi:cdc45_yeast(display_long)|uniprotkb:CDC45(gene name)|psi-mi:CDC45(display_short)|uniprotkb:YLR103C(locus name)|uniprotkb:L8004.11(orf name)|uniprotkb:SLD4(gene name synonym)	psi-mi:sld5_yeast(display_long)|uniprotkb:YDR489W(locus name)|uniprotkb:SLD5(gene name)|psi-mi:SLD5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tanaka et al. (2007)	pubmed:17167415|doi:10.1038/nature05465|imex:IM-21187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15615446|imex:IM-21187-4|dip:DIP-191083E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013204.1|sgd:S000004093|dip:DIP-2405N|mint:Q08032|ensemblfungi:YLR103C(gene)|ensemblfungi:YLR103C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-68962	sgd:S000002897|refseq:NP_010777.3|mint:Q03406|dip:DIP-1813N|ensemblfungi:YDR489W(gene)|ensemblfungi:YDR489W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:4C95|rcsb pdb:5NXQ|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-176974	psi-mi:"MI:0465"(dip)	crc64:6500DDD62EC4E8EE	crc64:7EC516ADAD9900DD	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:ErMEWxRKsJsPBDo5EfTfBL57hAY559292	rogid:O9Vu+11KYnU+PPCFaiCepQFayPM559292	rigid:beV3wZskX3rfCwQBiD906kELmR4	false	mutation increasing interaction strength:22-22|flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q08032	uniprotkb:P29469	intact:EBI-4292|uniprotkb:Q05908|uniprotkb:D6VYA3|ensemblfungi:YLR103C	intact:EBI-10533|ensemblfungi:YBL023C|uniprotkb:D6VPX7	psi-mi:cdc45_yeast(display_long)|uniprotkb:CDC45(gene name)|psi-mi:CDC45(display_short)|uniprotkb:YLR103C(locus name)|uniprotkb:L8004.11(orf name)|uniprotkb:SLD4(gene name synonym)	psi-mi:mcm2_yeast(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:YBL023C(locus name)|uniprotkb:YBL0438(orf name)|uniprotkb:Minichromosome maintenance protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tanaka et al. (2007)	pubmed:17167415|doi:10.1038/nature05465|imex:IM-21187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15615446|imex:IM-21187-4|dip:DIP-191083E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013204.1|sgd:S000004093|dip:DIP-2405N|mint:Q08032|ensemblfungi:YLR103C(gene)|ensemblfungi:YLR103C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-68962	refseq:NP_009530.1|sgd:S000000119|ensemblfungi:YBL023C(gene)|ensemblfungi:YBL023C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:3JA8|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5BK4|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:5V8F|rcsb pdb:5XF8|go:"GO:1902975"(mitotic DNA replication initiation)|rcsb pdb:6EYC|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6RQC|rcsb pdb:6SKL|rcsb pdb:6SKO|rcsb pdb:6U0M|rcsb pdb:6WGF|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68949|reactome:R-SCE-68962|reactome:R-SCE-69052|rcsb pdb:6F0L|mint:P29469|dip:DIP-2291N	psi-mi:"MI:0465"(dip)	crc64:6500DDD62EC4E8EE	crc64:F38FF682581B0EC0	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:ErMEWxRKsJsPBDo5EfTfBL57hAY559292	rogid:+XEStaQQNnAcfUIf1BVvFLgKG5k559292	rigid:beV3wZskX3rfCwQBiD906kELmR4	false	mutation increasing interaction strength:22-22|flag tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P47027	uniprotkb:P53135	intact:EBI-25984|uniprotkb:Q05712|uniprotkb:D6VW94|ensemblfungi:YJL090C	intact:EBI-23925|uniprotkb:D6VU34|ensemblfungi:YGL113W	psi-mi:dpb11_yeast(display_long)|uniprotkb:DPB11(gene name)|psi-mi:DPB11(display_short)|uniprotkb:J0918(orf name)|uniprotkb:YJL090C(locus name)	psi-mi:sld3_yeast(display_long)|uniprotkb:SLD3(gene name)|psi-mi:SLD3(display_short)|uniprotkb:G2980(orf name)|uniprotkb:YGL113W(locus name)	psi-mi:"MI:0018"(two hybrid)	Tanaka et al. (2007)	pubmed:17167415|doi:10.1038/nature05465|imex:IM-21187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15615469|imex:IM-21187-5|dip:DIP-187422E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003626|refseq:NP_012445.1|dip:DIP-5037N|ensemblfungi:YJL090C(gene)|ensemblfungi:YJL090C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007533"(mating type switching)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1902597"(positive regulation of DNA replication origin binding)|interpro:IPR001357(BRCT)|interpro:IPR036420	sgd:S000003081|refseq:NP_011402.3|dip:DIP-5481N|mint:P53135|ensemblfungi:YGL113W(gene)|ensemblfungi:YGL113W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR013948(DNA replication regulator Sld3)|interpro:IPR041393|interpro:IPR042511|rcsb pdb:3WI3	psi-mi:"MI:0465"(dip)	crc64:79B3A9BC7815E440	crc64:6E59D0DB3C082C28	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:CYn2Q78DOL/+HPutAsKRuKofolE559292	rogid:1uxenWX3lYYMDUWr0mAE207XsHI559292	rigid:qAs64ZNbIttjeGQqTIH4VT+iG9E	false	sufficient binding region:1-309	sufficient binding region:527-668|mutation disrupting interaction strength:622-622,600-600	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q08032	uniprotkb:P53135	intact:EBI-4292|uniprotkb:Q05908|uniprotkb:D6VYA3|ensemblfungi:YLR103C	intact:EBI-23925|uniprotkb:D6VU34|ensemblfungi:YGL113W	psi-mi:cdc45_yeast(display_long)|uniprotkb:CDC45(gene name)|psi-mi:CDC45(display_short)|uniprotkb:YLR103C(locus name)|uniprotkb:L8004.11(orf name)|uniprotkb:SLD4(gene name synonym)	psi-mi:sld3_yeast(display_long)|uniprotkb:SLD3(gene name)|psi-mi:SLD3(display_short)|uniprotkb:G2980(orf name)|uniprotkb:YGL113W(locus name)	psi-mi:"MI:0096"(pull down)	Tanaka et al. (2007)	pubmed:17167415|doi:10.1038/nature05465|imex:IM-21187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15615408|imex:IM-21187-2|dip:DIP-187424E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013204.1|sgd:S000004093|dip:DIP-2405N|mint:Q08032|ensemblfungi:YLR103C(gene)|ensemblfungi:YLR103C_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:3JC5|rcsb pdb:3JC6|rcsb pdb:3JC7|rcsb pdb:5U8S|rcsb pdb:5U8T|rcsb pdb:6HV9|rcsb pdb:6PTJ|rcsb pdb:6PTN|rcsb pdb:6PTO|rcsb pdb:6SKL|rcsb pdb:6U0M|reactome:R-SCE-68962	sgd:S000003081|refseq:NP_011402.3|dip:DIP-5481N|mint:P53135|ensemblfungi:YGL113W(gene)|ensemblfungi:YGL113W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR013948(DNA replication regulator Sld3)|interpro:IPR041393|interpro:IPR042511|rcsb pdb:3WI3	psi-mi:"MI:0465"(dip)	crc64:6500DDD62EC4E8EE	crc64:6E59D0DB3C082C28	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:ErMEWxRKsJsPBDo5EfTfBL57hAY559292	rogid:1uxenWX3lYYMDUWr0mAE207XsHI559292	rigid:uw4fgpDwG3RC5ozWdAdZjE0hM8g	false	tag:n-n	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P47027	uniprotkb:P53135	intact:EBI-25984|uniprotkb:Q05712|uniprotkb:D6VW94|ensemblfungi:YJL090C	intact:EBI-23925|uniprotkb:D6VU34|ensemblfungi:YGL113W	psi-mi:dpb11_yeast(display_long)|uniprotkb:DPB11(gene name)|psi-mi:DPB11(display_short)|uniprotkb:J0918(orf name)|uniprotkb:YJL090C(locus name)	psi-mi:sld3_yeast(display_long)|uniprotkb:SLD3(gene name)|psi-mi:SLD3(display_short)|uniprotkb:G2980(orf name)|uniprotkb:YGL113W(locus name)	psi-mi:"MI:0096"(pull down)	Tanaka et al. (2007)	pubmed:17167415|doi:10.1038/nature05465|imex:IM-21187	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15615494|imex:IM-21187-6|dip:DIP-187422E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003626|refseq:NP_012445.1|dip:DIP-5037N|ensemblfungi:YJL090C(gene)|ensemblfungi:YJL090C_mRNA(transcript)|go:"GO:0000076"(DNA replication checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005657"(replication fork)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007533"(mating type switching)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1902597"(positive regulation of DNA replication origin binding)|interpro:IPR001357(BRCT)|interpro:IPR036420	sgd:S000003081|refseq:NP_011402.3|dip:DIP-5481N|mint:P53135|ensemblfungi:YGL113W(gene)|ensemblfungi:YGL113W_mRNA(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007049"(cell cycle)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR013948(DNA replication regulator Sld3)|interpro:IPR041393|interpro:IPR042511|rcsb pdb:3WI3	psi-mi:"MI:0465"(dip)	crc64:79B3A9BC7815E440	crc64:6E59D0DB3C082C28	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:CYn2Q78DOL/+HPutAsKRuKofolE559292	rogid:1uxenWX3lYYMDUWr0mAE207XsHI559292	rigid:qAs64ZNbIttjeGQqTIH4VT+iG9E	false	calmodulin binding protein tag:c-c	sufficient binding region:527-668|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)