#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9Y3E7-1 uniprotkb:Q9Y3E7-1 intact:EBI-15613847|ensembl:ENSP00000263856 intact:EBI-15613847|ensembl:ENSP00000263856 psi-mi:q9y3e7-1(display_long)|uniprotkb:CHMP3(gene name)|psi-mi:CHMP3(display_short)|uniprotkb:CGI149(gene name synonym)|uniprotkb:NEDF(gene name synonym)|uniprotkb:VPS24(gene name synonym)|uniprotkb:Chromatin-modifying protein 3(gene name synonym)|uniprotkb:Neuroendocrine differentiation factor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 24(gene name synonym)|uniprotkb:CGI-149(orf name)|uniprotkb:Vps24alpha(isoform synonym) psi-mi:q9y3e7-1(display_long)|uniprotkb:CHMP3(gene name)|psi-mi:CHMP3(display_short)|uniprotkb:CGI149(gene name synonym)|uniprotkb:NEDF(gene name synonym)|uniprotkb:VPS24(gene name synonym)|uniprotkb:Chromatin-modifying protein 3(gene name synonym)|uniprotkb:Neuroendocrine differentiation factor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 24(gene name synonym)|uniprotkb:CGI-149(orf name)|uniprotkb:Vps24alpha(isoform synonym) psi-mi:"MI:0096"(pull down) Zamborlini et al. (2006) pubmed:17146056|doi:10.1073/pnas.0603788103|imex:IM-23998 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15613862|imex:IM-23998-1|dip:DIP-198440E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2118119(isoform-parent)|ensembl:ENSG00000115561(gene)|ensembl:ENST00000263856(transcript) intact:EBI-2118119(isoform-parent)|ensembl:ENSG00000115561(gene)|ensembl:ENST00000263856(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:mQEFHnkxyS1ZOfqKqGg9KtOjJFQ9606 rogid:mQEFHnkxyS1ZOfqKqGg9KtOjJFQ9606 rigid:R2JPynbRFguvdowwl1MBvT1KHx8 false flag tag:c-c|sufficient binding region:1-150 sufficient binding region:151-179|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y3E7-1 uniprotkb:Q9Y3E7-1 intact:EBI-15613847|ensembl:ENSP00000263856 intact:EBI-15613847|ensembl:ENSP00000263856 psi-mi:q9y3e7-1(display_long)|uniprotkb:CHMP3(gene name)|psi-mi:CHMP3(display_short)|uniprotkb:CGI149(gene name synonym)|uniprotkb:NEDF(gene name synonym)|uniprotkb:VPS24(gene name synonym)|uniprotkb:Chromatin-modifying protein 3(gene name synonym)|uniprotkb:Neuroendocrine differentiation factor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 24(gene name synonym)|uniprotkb:CGI-149(orf name)|uniprotkb:Vps24alpha(isoform synonym) psi-mi:q9y3e7-1(display_long)|uniprotkb:CHMP3(gene name)|psi-mi:CHMP3(display_short)|uniprotkb:CGI149(gene name synonym)|uniprotkb:NEDF(gene name synonym)|uniprotkb:VPS24(gene name synonym)|uniprotkb:Chromatin-modifying protein 3(gene name synonym)|uniprotkb:Neuroendocrine differentiation factor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 24(gene name synonym)|uniprotkb:CGI-149(orf name)|uniprotkb:Vps24alpha(isoform synonym) psi-mi:"MI:0096"(pull down) Zamborlini et al. (2006) pubmed:17146056|doi:10.1073/pnas.0603788103|imex:IM-23998 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15613887|imex:IM-23998-2|dip:DIP-198440E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2118119(isoform-parent)|ensembl:ENSG00000115561(gene)|ensembl:ENST00000263856(transcript) intact:EBI-2118119(isoform-parent)|ensembl:ENSG00000115561(gene)|ensembl:ENST00000263856(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:mQEFHnkxyS1ZOfqKqGg9KtOjJFQ9606 rogid:mQEFHnkxyS1ZOfqKqGg9KtOjJFQ9606 rigid:R2JPynbRFguvdowwl1MBvT1KHx8 false flag tag:c-c|sufficient binding region:1-113 glutathione s tranferase tag:n-n|sufficient binding region:151-222 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y3E7-1 uniprotkb:Q9Y3E7-1 intact:EBI-15613847|ensembl:ENSP00000263856 intact:EBI-15613847|ensembl:ENSP00000263856 psi-mi:q9y3e7-1(display_long)|uniprotkb:CHMP3(gene name)|psi-mi:CHMP3(display_short)|uniprotkb:CGI149(gene name synonym)|uniprotkb:NEDF(gene name synonym)|uniprotkb:VPS24(gene name synonym)|uniprotkb:Chromatin-modifying protein 3(gene name synonym)|uniprotkb:Neuroendocrine differentiation factor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 24(gene name synonym)|uniprotkb:CGI-149(orf name)|uniprotkb:Vps24alpha(isoform synonym) psi-mi:q9y3e7-1(display_long)|uniprotkb:CHMP3(gene name)|psi-mi:CHMP3(display_short)|uniprotkb:CGI149(gene name synonym)|uniprotkb:NEDF(gene name synonym)|uniprotkb:VPS24(gene name synonym)|uniprotkb:Chromatin-modifying protein 3(gene name synonym)|uniprotkb:Neuroendocrine differentiation factor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 24(gene name synonym)|uniprotkb:CGI-149(orf name)|uniprotkb:Vps24alpha(isoform synonym) psi-mi:"MI:0096"(pull down) Zamborlini et al. (2006) pubmed:17146056|doi:10.1073/pnas.0603788103|imex:IM-23998 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15613960|imex:IM-23998-5|dip:DIP-198440E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-2118119(isoform-parent)|ensembl:ENSG00000115561(gene)|ensembl:ENST00000263856(transcript) intact:EBI-2118119(isoform-parent)|ensembl:ENSG00000115561(gene)|ensembl:ENST00000263856(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:mQEFHnkxyS1ZOfqKqGg9KtOjJFQ9606 rogid:mQEFHnkxyS1ZOfqKqGg9KtOjJFQ9606 rigid:R2JPynbRFguvdowwl1MBvT1KHx8 false green fluorescent protein tag:c-c glutathione s tranferase tag:n-n|sufficient binding region:151-222 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UN37 uniprotkb:Q9Y3E7-1 intact:EBI-1171942|uniprotkb:Q8TF07|uniprotkb:Q9UI03|uniprotkb:Q9Y582|uniprotkb:B2RCB7|ensembl:ENSP00000254950 intact:EBI-15613847|ensembl:ENSP00000263856 psi-mi:vps4a_human(display_long)|uniprotkb:VPS4-1(gene name synonym)|uniprotkb:Protein SKD2(gene name synonym)|uniprotkb:VPS4A(gene name)|psi-mi:VPS4A(display_short)|uniprotkb:VPS4(gene name synonym) psi-mi:q9y3e7-1(display_long)|uniprotkb:CHMP3(gene name)|psi-mi:CHMP3(display_short)|uniprotkb:CGI149(gene name synonym)|uniprotkb:NEDF(gene name synonym)|uniprotkb:VPS24(gene name synonym)|uniprotkb:Chromatin-modifying protein 3(gene name synonym)|uniprotkb:Neuroendocrine differentiation factor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 24(gene name synonym)|uniprotkb:CGI-149(orf name)|uniprotkb:Vps24alpha(isoform synonym) psi-mi:"MI:0096"(pull down) Zamborlini et al. (2006) pubmed:17146056|doi:10.1073/pnas.0603788103|imex:IM-23998 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15613937|imex:IM-23998-4|dip:DIP-198442E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_037377.1|ensembl:ENSG00000132612(gene)|ensembl:ENST00000254950(transcript)|go:"GO:0000916"(actomyosin contractile ring contraction)|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007033"(vacuole organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009838"(abscission)|go:"GO:0010008"(endosome membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072319"(vesicle uncoating)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1903902"(positive regulation of viral life cycle)|go:"GO:1904896"(ESCRT complex disassembly)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR036181|interpro:IPR041569|mint:Q9UN37|rcsb pdb:1YXR|rcsb pdb:2JQ9|rcsb pdb:2K3W|reactome:R-HSA-162588|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9668328|interpro:IPR031255|dip:DIP-44585N intact:EBI-2118119(isoform-parent)|ensembl:ENSG00000115561(gene)|ensembl:ENST00000263856(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:kr3zmre/ELTm2b/fCytp8IlBUhs9606 rogid:mQEFHnkxyS1ZOfqKqGg9KtOjJFQ9606 rigid:FI/G3zC+74BtTcmTCpdPTqJ1obE false ha tag:c-c sufficient binding region:151-222|glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9D8B3 uniprotkb:Q9D8B3 intact:EBI-8322817|uniprotkb:Q922P1|intact:MINT-4092439|uniprotkb:Q3TXM7|uniprotkb:Q91VM7|uniprotkb:A2AVM1|ensembl:ENSMUSP00000036206 intact:EBI-8322817|uniprotkb:Q922P1|intact:MINT-4092439|uniprotkb:Q3TXM7|uniprotkb:Q91VM7|uniprotkb:A2AVM1|ensembl:ENSMUSP00000036206 psi-mi:chm4b_mouse(display_long)|uniprotkb:Chmp4b(gene name)|psi-mi:Chmp4b(display_short)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym) psi-mi:chm4b_mouse(display_long)|uniprotkb:Chmp4b(gene name)|psi-mi:Chmp4b(display_short)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym) psi-mi:"MI:0096"(pull down) Zamborlini et al. (2006) pubmed:17146056|doi:10.1073/pnas.0603788103|imex:IM-23998 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15613912|imex:IM-23998-3|dip:DIP-198441E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_083638.1|dip:DIP-61322N|ensembl:ENSMUSG00000038467(gene)|ensembl:ENSMUST00000044277(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9D8B3|reactome:R-MMU-1632852|reactome:R-MMU-5620971|reactome:R-MMU-917729|reactome:R-MMU-9668328 refseq:NP_083638.1|dip:DIP-61322N|ensembl:ENSMUSG00000038467(gene)|ensembl:ENSMUST00000044277(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9D8B3|reactome:R-MMU-1632852|reactome:R-MMU-5620971|reactome:R-MMU-917729|reactome:R-MMU-9668328 psi-mi:"MI:0465"(dip) comment:mint|function:"Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-I complex on endosomal membranes" comment:mint|function:"Component of the ESCRT-III complex, which is required for multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-III complex is probably involved in the concentration of MVB cargo. In the ESCRT-III complex, it probably serves as an acceptor for ESCRT-I complex on endosomal membranes" full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:7ObtifCzEVN9ohyQMVv/eHUJd+810090 rogid:7ObtifCzEVN9ohyQMVv/eHUJd+810090 rigid:02/GnonyJCo46nAV1D8XPt9oHRw false flag tag:c-c|sufficient binding region:1-153 glutathione s tranferase tag:n-n|sufficient binding region:154-224 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:O95630 uniprotkb:Q9Y3E7-1 intact:EBI-396676|uniprotkb:Q3MJE7|uniprotkb:D6W5H7|uniprotkb:B5M0B6|ensembl:ENSP00000344742|ensembl:ENSP00000377633|ensembl:ENSP00000377636|ensembl:ENSP00000386548|ensembl:ENSP00000506833|ensembl:ENSP00000506845|ensembl:ENSP00000506865|ensembl:ENSP00000506958|ensembl:ENSP00000507014|ensembl:ENSP00000507054|ensembl:ENSP00000507081|ensembl:ENSP00000507092|ensembl:ENSP00000507639|ensembl:ENSP00000507658|ensembl:ENSP00000507864 intact:EBI-15613847|ensembl:ENSP00000263856 psi-mi:stabp_human(display_long)|uniprotkb:AMSH(gene name synonym)|uniprotkb:STAMBP(gene name)|psi-mi:STAMBP(display_short)|uniprotkb:Associated molecule with the SH3 domain of STAM(gene name synonym)|uniprotkb:Endosome-associated ubiquitin isopeptidase(gene name synonym) psi-mi:q9y3e7-1(display_long)|uniprotkb:CHMP3(gene name)|psi-mi:CHMP3(display_short)|uniprotkb:CGI149(gene name synonym)|uniprotkb:NEDF(gene name synonym)|uniprotkb:VPS24(gene name synonym)|uniprotkb:Chromatin-modifying protein 3(gene name synonym)|uniprotkb:Neuroendocrine differentiation factor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 24(gene name synonym)|uniprotkb:CGI-149(orf name)|uniprotkb:Vps24alpha(isoform synonym) psi-mi:"MI:0096"(pull down) Zamborlini et al. (2006) pubmed:17146056|doi:10.1073/pnas.0603788103|imex:IM-23998 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15613983|imex:IM-23998-6|dip:DIP-132579E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006454.1|refseq:NP_964010.1|refseq:NP_998787.1|refseq:XP_005264145.1|refseq:XP_011530785.1|refseq:XP_016858664.1|go:"GO:0016020"(membrane)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR037518|interpro:IPR044098|mint:O95630|rcsb pdb:2XZE|rcsb pdb:3RZU|rcsb pdb:3RZV|rcsb pdb:5IXF|reactome:R-HSA-5689901|ensembl:ENSG00000124356(gene)|ensembl:ENST00000339566(transcript)|ensembl:ENST00000394070(transcript)|ensembl:ENST00000394073(transcript)|ensembl:ENST00000409707(transcript)|ensembl:ENST00000682351(transcript)|ensembl:ENST00000682379(transcript)|ensembl:ENST00000682558(transcript)|ensembl:ENST00000682847(transcript)|ensembl:ENST00000683036(transcript)|ensembl:ENST00000683317(transcript)|ensembl:ENST00000683518(transcript)|ensembl:ENST00000683818(transcript)|ensembl:ENST00000684095(transcript)|ensembl:ENST00000684312(transcript)|ensembl:ENST00000684585(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|dip:DIP-33062N intact:EBI-2118119(isoform-parent)|ensembl:ENSG00000115561(gene)|ensembl:ENST00000263856(transcript) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:JUvszgPz9rog/OEpmABJ295BaLw9606 rogid:mQEFHnkxyS1ZOfqKqGg9KtOjJFQ9606 rigid:8Mc9t8NeQDBu8J1ACrVdZzL/wno false ha tag:c-c sufficient binding region:151-222|glutathione s tranferase tag:n-n|mutation disrupting interaction strength:217-217,216-216 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)