#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-4399559 uniprotkb:Q86VN1 dip:DIP-24261N intact:EBI-4401822|uniprotkb:A8K125|uniprotkb:Q3ZCV7|uniprotkb:Q5H9S1|uniprotkb:Q5VXB6|uniprotkb:Q9H8Z5|uniprotkb:Q9Y3E3|ensembl:ENSP00000367299 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:vps36_human(display_long)|uniprotkb:VPS36(gene name)|psi-mi:VPS36(display_short)|uniprotkb:C13orf9(gene name synonym)|uniprotkb:EAP45(gene name synonym)|uniprotkb:ELL-associated protein of 45 kDa(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS36(gene name synonym)|uniprotkb:CGI-145(orf name) psi-mi:"MI:0114"(x-ray crystallography) Alam et al. (2006) pubmed:17057716|doi:10.1038/nsmb1160|imex:IM-8591 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15607845|imex:IM-8591-2|dip:DIP-57272E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_057159.2|refseq:NP_001269098.1|dip:DIP-29249N|ensembl:ENSG00000136100(gene)|ensembl:ENST00000378060(transcript)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021648|interpro:IPR036388|interpro:IPR036390|interpro:IPR037855|interpro:IPR040608|rcsb pdb:2HTH|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379 psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:LPnQXFgph4C6q8VJu1Fgrhn6clM9606 rigid:CTMQEicOP09tQUg44/ARGEsSF4w false - sufficient binding region:1-139 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4399559 uniprotkb:Q86VN1 dip:DIP-24261N intact:EBI-4401822|uniprotkb:A8K125|uniprotkb:Q3ZCV7|uniprotkb:Q5H9S1|uniprotkb:Q5VXB6|uniprotkb:Q9H8Z5|uniprotkb:Q9Y3E3|ensembl:ENSP00000367299 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:vps36_human(display_long)|uniprotkb:VPS36(gene name)|psi-mi:VPS36(display_short)|uniprotkb:C13orf9(gene name synonym)|uniprotkb:EAP45(gene name synonym)|uniprotkb:ELL-associated protein of 45 kDa(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS36(gene name synonym)|uniprotkb:CGI-145(orf name) psi-mi:"MI:0107"(surface plasmon resonance) Alam et al. (2006) pubmed:17057716|doi:10.1038/nsmb1160|imex:IM-8591 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15607864|imex:IM-8591-3|dip:DIP-57272E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_057159.2|refseq:NP_001269098.1|dip:DIP-29249N|ensembl:ENSG00000136100(gene)|ensembl:ENST00000378060(transcript)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021648|interpro:IPR036388|interpro:IPR036390|interpro:IPR037855|interpro:IPR040608|rcsb pdb:2HTH|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379 psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:LPnQXFgph4C6q8VJu1Fgrhn6clM9606 rigid:CTMQEicOP09tQUg44/ARGEsSF4w false experimental feature:0-0 sufficient binding region:1-139 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-4399559 uniprotkb:Q86VN1 dip:DIP-24261N intact:EBI-4401822|uniprotkb:A8K125|uniprotkb:Q3ZCV7|uniprotkb:Q5H9S1|uniprotkb:Q5VXB6|uniprotkb:Q9H8Z5|uniprotkb:Q9Y3E3|ensembl:ENSP00000367299 psi-mi:ubiq_human(display_short)|psi-mi:EBI-4399559(display_long) psi-mi:vps36_human(display_long)|uniprotkb:VPS36(gene name)|psi-mi:VPS36(display_short)|uniprotkb:C13orf9(gene name synonym)|uniprotkb:EAP45(gene name synonym)|uniprotkb:ELL-associated protein of 45 kDa(gene name synonym)|uniprotkb:ESCRT-II complex subunit VPS36(gene name synonym)|uniprotkb:CGI-145(orf name) psi-mi:"MI:0107"(surface plasmon resonance) Alam et al. (2006) pubmed:17057716|doi:10.1038/nsmb1160|imex:IM-8591 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15607885|imex:IM-8591-1|dip:DIP-57272E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) uniprotkb:UBIQ_HUMAN(see-also)|refseq:NP_066289.2 refseq:NP_057159.2|refseq:NP_001269098.1|dip:DIP-29249N|ensembl:ENSG00000136100(gene)|ensembl:ENST00000378060(transcript)|go:"GO:0000814"(ESCRT II complex)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016236"(macroautophagy)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021648|interpro:IPR036388|interpro:IPR036390|interpro:IPR037855|interpro:IPR040608|rcsb pdb:2HTH|rcsb pdb:2ZME|rcsb pdb:3CUQ|reactome:R-HSA-917729|reactome:R-HSA-9610379 psi-mi:"MI:0465"(dip) no-uniprot-update: - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/15 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9606 rogid:LPnQXFgph4C6q8VJu1Fgrhn6clM9606 rigid:CTMQEicOP09tQUg44/ARGEsSF4w false mutation decreasing interaction:44-44 sufficient binding region:1-139|experimental feature:n-n|mutation decreasing interaction:67-67|mutation decreasing interaction:68-68|mutation decreasing interaction:70-70 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)