#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q62897	uniprotkb:Q9NZI2	intact:EBI-7082853|uniprotkb:Q63286|uniprotkb:O08723|uniprotkb:Q99P42|intact:MINT-103596|uniprotkb:P70622	intact:EBI-2120635|uniprotkb:Q5U822|uniprotkb:B7Z7B4|ensembl:ENSP00000395323|uniprotkb:Q3YAD2|uniprotkb:Q3YAD0|uniprotkb:Q3YAD1|uniprotkb:Q3YAD3|intact:EBI-12174367|uniprotkb:A0A0C4DFQ7	psi-mi:kcnd3_rat(display_long)|uniprotkb:Kcnd3(gene name)|psi-mi:Kcnd3(display_short)|uniprotkb:Voltage-gated potassium channel subunit Kv4.3(gene name synonym)	psi-mi:kcip1_human(display_long)|uniprotkb:KCNIP1(gene name)|psi-mi:KCNIP1(display_short)|uniprotkb:KCHIP1(gene name synonym)|uniprotkb:VABP(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 1(gene name synonym)|uniprotkb:Potassium channel-interacting protein 1(gene name synonym)|uniprotkb:Vesicle APC-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Pioletti et al. (2006)	pubmed:17057713|doi:10.1038/nsmb1164|imex:IM-8588	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15607653|imex:IM-8588-1|dip:DIP-57269E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-RNO-1296072|reactome:R-RNO-5576894|go:"GO:0005216"(ion channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005250"("A-type (transient outward) potassium channel activity")|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099625"(ventricular cardiac muscle cell membrane repolarization)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003975(Potassium channel, voltage dependent, Kv4)|interpro:IPR004056(Potassium channel, voltage dependent, Kv4.3)|interpro:IPR005821(Ion transport)|interpro:IPR021645|interpro:IPR024587|interpro:IPR027359|interpro:IPR028325|rcsb pdb:2I2R|interpro:IPR011333(BTB/POZ fold)|refseq:NP_113927.2|rgd:68394|refseq:NP_001257892.1|refseq:NP_001257891.1|dip:DIP-29245N	refseq:NP_001030009.1|refseq:NP_055407.1|refseq:NP_001030010.1|refseq:NP_001265268.1|refseq:NP_001265269.1|refseq:XP_016864896.1|dip:DIP-29246N|ensembl:ENSG00000182132(gene)|ensembl:ENST00000411494(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:Q9NZI2|rcsb pdb:1S1E|rcsb pdb:2NZ0|reactome:R-HSA-5576894|rcsb pdb:2I2R	psi-mi:"MI:0465"(dip)	comment:mint|function:"Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:zJN5DkxofoEqmQzUGj9XmQuwDms10116	rogid:+4k81JjvVvA1ODWgsux/34foDFY9606	rigid:ap3QdtXlcuzFxQwdglbwu/nI6Xo	false	sufficient binding region:1-143	sufficient binding region:37-216|mutation decreasing interaction strength:194-194,146-146	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62897	uniprotkb:Q9NZI2	intact:EBI-7082853|uniprotkb:Q63286|uniprotkb:O08723|uniprotkb:Q99P42|intact:MINT-103596|uniprotkb:P70622	intact:EBI-2120635|uniprotkb:Q5U822|uniprotkb:B7Z7B4|ensembl:ENSP00000395323|uniprotkb:Q3YAD2|uniprotkb:Q3YAD0|uniprotkb:Q3YAD1|uniprotkb:Q3YAD3|intact:EBI-12174367|uniprotkb:A0A0C4DFQ7	psi-mi:kcnd3_rat(display_long)|uniprotkb:Kcnd3(gene name)|psi-mi:Kcnd3(display_short)|uniprotkb:Voltage-gated potassium channel subunit Kv4.3(gene name synonym)	psi-mi:kcip1_human(display_long)|uniprotkb:KCNIP1(gene name)|psi-mi:KCNIP1(display_short)|uniprotkb:KCHIP1(gene name synonym)|uniprotkb:VABP(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 1(gene name synonym)|uniprotkb:Potassium channel-interacting protein 1(gene name synonym)|uniprotkb:Vesicle APC-binding protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Pioletti et al. (2006)	pubmed:17057713|doi:10.1038/nsmb1164|imex:IM-8588	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15607678|imex:IM-8588-2|dip:DIP-57269E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-RNO-1296072|reactome:R-RNO-5576894|go:"GO:0005216"(ion channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005250"("A-type (transient outward) potassium channel activity")|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099625"(ventricular cardiac muscle cell membrane repolarization)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003975(Potassium channel, voltage dependent, Kv4)|interpro:IPR004056(Potassium channel, voltage dependent, Kv4.3)|interpro:IPR005821(Ion transport)|interpro:IPR021645|interpro:IPR024587|interpro:IPR027359|interpro:IPR028325|rcsb pdb:2I2R|interpro:IPR011333(BTB/POZ fold)|refseq:NP_113927.2|rgd:68394|refseq:NP_001257892.1|refseq:NP_001257891.1|dip:DIP-29245N	refseq:NP_001030009.1|refseq:NP_055407.1|refseq:NP_001030010.1|refseq:NP_001265268.1|refseq:NP_001265269.1|refseq:XP_016864896.1|dip:DIP-29246N|ensembl:ENSG00000182132(gene)|ensembl:ENST00000411494(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:Q9NZI2|rcsb pdb:1S1E|rcsb pdb:2NZ0|reactome:R-HSA-5576894|rcsb pdb:2I2R	psi-mi:"MI:0465"(dip)	comment:mint|function:"Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:zJN5DkxofoEqmQzUGj9XmQuwDms10116	rogid:+4k81JjvVvA1ODWgsux/34foDFY9606	rigid:ap3QdtXlcuzFxQwdglbwu/nI6Xo	false	sufficient binding region:1-143	sufficient binding region:37-216	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62897	uniprotkb:Q9NZI2	intact:EBI-7082853|uniprotkb:Q63286|uniprotkb:O08723|uniprotkb:Q99P42|intact:MINT-103596|uniprotkb:P70622	intact:EBI-2120635|uniprotkb:Q5U822|uniprotkb:B7Z7B4|ensembl:ENSP00000395323|uniprotkb:Q3YAD2|uniprotkb:Q3YAD0|uniprotkb:Q3YAD1|uniprotkb:Q3YAD3|intact:EBI-12174367|uniprotkb:A0A0C4DFQ7	psi-mi:kcnd3_rat(display_long)|uniprotkb:Kcnd3(gene name)|psi-mi:Kcnd3(display_short)|uniprotkb:Voltage-gated potassium channel subunit Kv4.3(gene name synonym)	psi-mi:kcip1_human(display_long)|uniprotkb:KCNIP1(gene name)|psi-mi:KCNIP1(display_short)|uniprotkb:KCHIP1(gene name synonym)|uniprotkb:VABP(gene name synonym)|uniprotkb:A-type potassium channel modulatory protein 1(gene name synonym)|uniprotkb:Potassium channel-interacting protein 1(gene name synonym)|uniprotkb:Vesicle APC-binding protein(gene name synonym)	psi-mi:"MI:0826"(x ray scattering)	Pioletti et al. (2006)	pubmed:17057713|doi:10.1038/nsmb1164|imex:IM-8588	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15607699|imex:IM-8588-3|dip:DIP-57269E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-RNO-1296072|reactome:R-RNO-5576894|go:"GO:0005216"(ion channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005250"("A-type (transient outward) potassium channel activity")|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0034705"(potassium channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071773"(cellular response to BMP stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:0099625"(ventricular cardiac muscle cell membrane repolarization)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003975(Potassium channel, voltage dependent, Kv4)|interpro:IPR004056(Potassium channel, voltage dependent, Kv4.3)|interpro:IPR005821(Ion transport)|interpro:IPR021645|interpro:IPR024587|interpro:IPR027359|interpro:IPR028325|rcsb pdb:2I2R|interpro:IPR011333(BTB/POZ fold)|refseq:NP_113927.2|rgd:68394|refseq:NP_001257892.1|refseq:NP_001257891.1|dip:DIP-29245N	refseq:NP_001030009.1|refseq:NP_055407.1|refseq:NP_001030010.1|refseq:NP_001265268.1|refseq:NP_001265269.1|refseq:XP_016864896.1|dip:DIP-29246N|ensembl:ENSG00000182132(gene)|ensembl:ENST00000411494(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|mint:Q9NZI2|rcsb pdb:1S1E|rcsb pdb:2NZ0|reactome:R-HSA-5576894|rcsb pdb:2I2R	psi-mi:"MI:0465"(dip)	comment:mint|function:"Pore-forming (alpha) subunit of voltage-gated rapidly inactivating A-type potassium channels. May contribute to I(To) current in heart and I(Sa) current in neurons. Channel properties are modulated by interactions with other alpha subunits and with regulatory subunits"	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:zJN5DkxofoEqmQzUGj9XmQuwDms10116	rogid:+4k81JjvVvA1ODWgsux/34foDFY9606	rigid:ap3QdtXlcuzFxQwdglbwu/nI6Xo	false	sufficient binding region:1-143	sufficient binding region:37-216	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)