#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P17629 uniprotkb:Q99257 intact:EBI-8526|uniprotkb:Q03918|uniprotkb:D6VSC1|ensemblfungi:YDR138W intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9 psi-mi:hpr1_yeast(display_long)|uniprotkb:HPR1(gene name)|psi-mi:HPR1(display_short)|uniprotkb:YDR138W(locus name)|uniprotkb:YD9302.14(orf name)|uniprotkb:Hyperrecombination protein 1(gene name synonym) psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15607505|imex:IM-23953-3|dip:DIP-198171E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010422.1|sgd:S000002545|mint:P17629|dip:DIP-6266N|ensemblfungi:YDR138W(gene)|ensemblfungi:YDR138W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021861|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N psi-mi:"MI:0465"(dip) crc64:CBD92432F099AD22 crc64:6CE55EEC6FA40B40 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:7P/07YrijkKMlCOGGes6+v/eLkE559292 rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292 rigid:5cZFbG9U9fKIIzs37WI9jhV8TV4 false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99257 uniprotkb:P17629 intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9 intact:EBI-8526|uniprotkb:Q03918|uniprotkb:D6VSC1|ensemblfungi:YDR138W psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name) psi-mi:hpr1_yeast(display_long)|uniprotkb:HPR1(gene name)|psi-mi:HPR1(display_short)|uniprotkb:YDR138W(locus name)|uniprotkb:YD9302.14(orf name)|uniprotkb:Hyperrecombination protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15607486|imex:IM-23953-2|dip:DIP-198171E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N refseq:NP_010422.1|sgd:S000002545|mint:P17629|dip:DIP-6266N|ensemblfungi:YDR138W(gene)|ensemblfungi:YDR138W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021861|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV psi-mi:"MI:0465"(dip) crc64:6CE55EEC6FA40B40 crc64:CBD92432F099AD22 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292 rogid:7P/07YrijkKMlCOGGes6+v/eLkE559292 rigid:5cZFbG9U9fKIIzs37WI9jhV8TV4 false - sufficient binding region:548-752 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q99257 uniprotkb:P17629 intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9 intact:EBI-8526|uniprotkb:Q03918|uniprotkb:D6VSC1|ensemblfungi:YDR138W psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name) psi-mi:hpr1_yeast(display_long)|uniprotkb:HPR1(gene name)|psi-mi:HPR1(display_short)|uniprotkb:YDR138W(locus name)|uniprotkb:YD9302.14(orf name)|uniprotkb:Hyperrecombination protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15607465|imex:IM-23953-1|dip:DIP-198171E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N refseq:NP_010422.1|sgd:S000002545|mint:P17629|dip:DIP-6266N|ensemblfungi:YDR138W(gene)|ensemblfungi:YDR138W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021861|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV psi-mi:"MI:0465"(dip) crc64:6CE55EEC6FA40B40 crc64:CBD92432F099AD22 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292 rogid:7P/07YrijkKMlCOGGes6+v/eLkE559292 rigid:5cZFbG9U9fKIIzs37WI9jhV8TV4 false sufficient binding region:543-599 sufficient binding region:548-752 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-19797 uniprotkb:Q99257 dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96 intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9 psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name) psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name) psi-mi:"MI:0096"(pull down) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15607524|imex:IM-23953-4|dip:DIP-198173E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N psi-mi:"MI:0465"(dip) no-uniprot-update:obsolete protein crc64:6CE55EEC6FA40B40 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/15 rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932 rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292 rigid:0I4Zu/F//yOq2Dov/YWDFDQVKgw false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) intact:EBI-19797 uniprotkb:Q99257 dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96 intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9 psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name) psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15607543|imex:IM-23953-5|dip:DIP-198173E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N psi-mi:"MI:0465"(dip) no-uniprot-update:obsolete protein crc64:6CE55EEC6FA40B40 comment:Deletion of region 543-599 decreased the interaction rate/strength.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/15 rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932 rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292 rigid:0I4Zu/F//yOq2Dov/YWDFDQVKgw false dansyl label:0-0 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17629 intact:EBI-19797 intact:EBI-8526|uniprotkb:Q03918|uniprotkb:D6VSC1|ensemblfungi:YDR138W dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96 psi-mi:hpr1_yeast(display_long)|uniprotkb:HPR1(gene name)|psi-mi:HPR1(display_short)|uniprotkb:YDR138W(locus name)|uniprotkb:YD9302.14(orf name)|uniprotkb:Hyperrecombination protein 1(gene name synonym) psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name) psi-mi:"MI:0096"(pull down) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15607605|imex:IM-23953-8|dip:DIP-198174E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010422.1|sgd:S000002545|mint:P17629|dip:DIP-6266N|ensemblfungi:YDR138W(gene)|ensemblfungi:YDR138W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021861|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI psi-mi:"MI:0465"(dip) crc64:CBD92432F099AD22 no-uniprot-update:obsolete protein full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/15 rogid:7P/07YrijkKMlCOGGes6+v/eLkE559292 rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932 rigid:dmEexnDl7sJON4jRiI4gAP0ET1w false ha tag:c-c his tag:0-0 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99257 uniprotkb:P17629 intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9 intact:EBI-8526|uniprotkb:Q03918|uniprotkb:D6VSC1|ensemblfungi:YDR138W psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name) psi-mi:hpr1_yeast(display_long)|uniprotkb:HPR1(gene name)|psi-mi:HPR1(display_short)|uniprotkb:YDR138W(locus name)|uniprotkb:YD9302.14(orf name)|uniprotkb:Hyperrecombination protein 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15607582|imex:IM-23953-7|dip:DIP-198171E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N refseq:NP_010422.1|sgd:S000002545|mint:P17629|dip:DIP-6266N|ensemblfungi:YDR138W(gene)|ensemblfungi:YDR138W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:2001209"(positive regulation of transcription elongation from RNA polymerase I promoter)|interpro:IPR021861|rcsb pdb:7APX|rcsb pdb:7AQO|rcsb pdb:7LUV psi-mi:"MI:0465"(dip) crc64:6CE55EEC6FA40B40 crc64:CBD92432F099AD22 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292 rogid:7P/07YrijkKMlCOGGes6+v/eLkE559292 rigid:5cZFbG9U9fKIIzs37WI9jhV8TV4 false sufficient binding region:543-599 sufficient binding region:548-752|glutathione s tranferase tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O13539 uniprotkb:Q99257 intact:EBI-30898|uniprotkb:D3DLB6|ensemblfungi:YHR167W intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9 psi-mi:thp2_yeast(display_long)|uniprotkb:THP2(gene name)|psi-mi:THP2(display_short)|uniprotkb:YHR167W(locus name) psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15607563|imex:IM-23953-6|dip:DIP-198172E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012037.1|sgd:S000001210|dip:DIP-4246N|mint:O13539|ensemblfungi:YHR167W(gene)|ensemblfungi:YHR167W_mRNA(transcript)|go:"GO:0000445"(THO complex part of transcription export complex)|go:"GO:0000446"(nucleoplasmic THO complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0006310"(DNA recombination)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0034063"(stress granule assembly)|interpro:IPR018557|rcsb pdb:7APX|rcsb pdb:7LUV ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N psi-mi:"MI:0465"(dip) crc64:16EFA6F464507C57 crc64:6CE55EEC6FA40B40 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:SaTSL6jLwX1hTVCqvU8ZNR96r8U559292 rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292 rigid:ZBT/uWatT53hoSzDBSDUzlICZyg false ha tag:c-c - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P32628 intact:EBI-19797 intact:EBI-14668|uniprotkb:D3DLL2|ensemblfungi:YEL037C dip:DIP-1549N|uniprotkb:P04838|uniprotkb:Q6LA96 psi-mi:rad23_yeast(display_long)|uniprotkb:SYGP-ORF29(orf name)|uniprotkb:YEL037C(locus name)|uniprotkb:RAD23(gene name)|psi-mi:RAD23(display_short) psi-mi:ubiq_yeast(display_short)|psi-mi:EBI-19797(display_long)|uniprotkb:UBI1(gene name)|psi-mi:UBI1(display_short)|uniprotkb:RPL40A(gene name synonym)|uniprotkb:YIL148W(locus name)|uniprotkb:UBI2(gene name)|psi-mi:UBI2(display_short)|uniprotkb:RPL40B(gene name synonym)|uniprotkb:YKR094C(locus name)|uniprotkb:UBI3(gene name)|psi-mi:UBI3(display_short)|uniprotkb:RPS31(gene name synonym)|uniprotkb:YLR167W(locus name)|uniprotkb:L9470.14(orf name)|uniprotkb:UBI4(gene name)|psi-mi:UBI4(display_short)|uniprotkb:SCD2(gene name synonym)|uniprotkb:YLL039C(locus name) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Gwizdek et al. (2006) pubmed:17056718|doi:10.1073/pnas.0607941103|imex:IM-23953 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15607626|imex:IM-23953-9|dip:DIP-3847E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000763|ensemblfungi:YEL037C(gene)|ensemblfungi:YEL037C_mRNA(transcript)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|reactome:R-SCE-5696395|reactome:R-SCE-532668|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR029071|interpro:IPR036353|rcsb pdb:1X3W|rcsb pdb:1X3Z|rcsb pdb:2NBU|rcsb pdb:2NBW|rcsb pdb:2QSF|rcsb pdb:2QSG|rcsb pdb:2QSH|rcsb pdb:3ESW|rcsb pdb:3M62|rcsb pdb:4YIR|rcsb pdb:6CFI|rcsb pdb:6UBF|interpro:IPR006636(Heat shock chaperonin-binding)|rcsb pdb:6UG1|rcsb pdb:6UIN|refseq:NP_010877.3|dip:DIP-1548N|mint:P32628 sgd:S000001410(RPL40A)|sgd:S000001802(RPL40B)|sgd:S000004157(RPS31)|sgd:S000003962(UBI4)|uniprotkb:P61864(see-also)|refseq:NP_012118.1|refseq:NP_013020.1|refseq:NP_013061.1|refseq:NP_013268.1|ensembl:YIL148W|ensembl:YKR094C|ensembl:YLR167W|go:"GO:0005515"(protein binding)|interpro:IPR000626(Ubiquitin)|cygd:YLR167w|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0005739"(mitochondrion)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0006412"(translation)|ensembl:YLL039C|rcsb pdb:1OTR|rcsb pdb:1Q0W|rcsb pdb:1WR1|rcsb pdb:1ZW7|rcsb pdb:2G3Q|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|cygd:YIL148w|cygd:YKR094c|cygd:YLL039c|rcsb pdb:2JT4|rcsb pdb:2JWZ|rcsb pdb:3CMM|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3L0W|rcsb pdb:3L10|rcsb pdb:3MHS|rcsb pdb:2KDI psi-mi:"MI:0465"(dip) crc64:B3F0436DAB60B833 no-uniprot-update:obsolete protein full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/15 rogid:6Pl+Ctv8QBaoAY9m5xHv/qa/z7w559292 rogid:sUFDb7kGedoC/k80bI4sjOaMLHs4932 rigid:YErqAYfiEMyEZ6ZCT5AD7nesjDw false - dansyl label:0-0 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)