#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q60748	uniprotkb:P70424	intact:EBI-15606124|ensembl:ENSMUSP00000148297|uniprotkb:B9EHB5|uniprotkb:Q5GL24|uniprotkb:Q60783|uniprotkb:Q60808	intact:EBI-2945468|ensembl:ENSMUSP00000053897|uniprotkb:Q61525|uniprotkb:Q6ZPE0	psi-mi:crfr2_mouse(display_long)|uniprotkb:CRF-RB(gene name synonym)|uniprotkb:Corticotropin-releasing hormone receptor 2(gene name synonym)|uniprotkb:Crhr2(gene name)|psi-mi:Crhr2(display_short)|uniprotkb:Crf2r(gene name synonym)	psi-mi:erbb2_mouse(display_long)|uniprotkb:Erbb2(gene name)|psi-mi:Erbb2(display_short)|uniprotkb:Kiaa3023(gene name synonym)|uniprotkb:Neu(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:p185erbB2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Negro et al. (2006)	pubmed:17043217|doi:10.1073/pnas.0607499103|imex:IM-23944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15606164|imex:IM-23944-1|dip:DIP-198157E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070852"(cell body fiber)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:2000252"(negative regulation of feeding behavior)|go:"GO:2000293"(negative regulation of defecation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003051(GPCR, family 2, corticotropin releasing factor receptor)|interpro:IPR003053(GPCR, family 2, corticotropin releasing factor receptor, type 2)|interpro:IPR017981|interpro:IPR017983|interpro:IPR036445|rcsb pdb:1U34|rcsb pdb:2JNC|rcsb pdb:2JND|reactome:R-MMU-373080|reactome:R-MMU-418555|go:"GO:0060291"(long-term synaptic potentiation)|ensembl:ENSMUSG00000003476(gene)|ensembl:ENSMUST00000213026(transcript)|go:"GO:0005179"(hormone activity)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008528"(G protein-coupled peptide receptor activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010700"(negative regulation of norepinephrine secretion)|go:"GO:0015056"(corticotrophin-releasing factor receptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032811"(negative regulation of epinephrine secretion)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033685"(negative regulation of luteinizing hormone secretion)|go:"GO:0035482"(gastric motility)|go:"GO:0042423"(catecholamine biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043204"(perikaryon)|go:"GO:0043404"(corticotropin-releasing hormone receptor activity)|go:"GO:0043679"(axon terminus)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046882"(negative regulation of follicle-stimulating hormone secretion)|go:"GO:0048630"(skeletal muscle tissue growth)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0014064"(positive regulation of serotonin secretion)|refseq:NP_001275548.1|dip:DIP-61295N	ensembl:ENSMUSG00000062312(gene)|ensembl:ENSMUST00000058295(transcript)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010008"(endosome membrane)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042060"(wound healing)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|reactome:R-MMU-1227986|reactome:R-MMU-1250196|reactome:R-MMU-1257604|reactome:R-MMU-1963640|reactome:R-MMU-1963642|reactome:R-MMU-416572|reactome:R-MMU-5673001|reactome:R-MMU-6785631|reactome:R-MMU-6811558|reactome:R-MMU-8847993|reactome:R-MMU-8863795|reactome:R-MMU-9652282|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|refseq:NP_001003817.1|dip:DIP-40912N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2017/08/05	2017/08/10	rogid:pYZjFC9kGaB4ZcDH8Dj8plB2yLM10090	rogid:+lOIwIPXJnyC0pwki4J6+7mk1+w10090	rigid:ise0rniSdsMN4ChzC1j64EZjFac	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P18762	uniprotkb:P70424	intact:EBI-491143|uniprotkb:Q8BH38|ensembl:ENSMUSP00000062256	intact:EBI-2945468|ensembl:ENSMUSP00000053897|uniprotkb:Q61525|uniprotkb:Q6ZPE0	psi-mi:adrb2_mouse(display_long)|uniprotkb:Beta-2 adrenoreceptor(gene name synonym)|uniprotkb:Adrb2(gene name)|psi-mi:Adrb2(display_short)|uniprotkb:Adrb2r(gene name synonym)	psi-mi:erbb2_mouse(display_long)|uniprotkb:Erbb2(gene name)|psi-mi:Erbb2(display_short)|uniprotkb:Kiaa3023(gene name synonym)|uniprotkb:Neu(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:p185erbB2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Negro et al. (2006)	pubmed:17043217|doi:10.1073/pnas.0607499103|imex:IM-23944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15606183|imex:IM-23944-2|dip:DIP-198158E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005901"(caveola)|refseq:NP_031446.2|ensembl:ENSMUSG00000045730(gene)|ensembl:ENSMUST00000053640(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001993"(regulation of systemic arterial blood pressure by norepinephrine-epinephrine)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002025"(norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002086"(diaphragm contraction)|go:"GO:0003059"(positive regulation of the force of heart contraction by epinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004941"(beta2-adrenergic receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019899"(enzyme binding)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031649"(heat generation)|go:"GO:0031713"(B2 bradykinin receptor binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051380"(norepinephrine binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061885"(positive regulation of mini excitatory postsynaptic potential)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905665"(positive regulation of calcium ion import across plasma membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000332(Adrenergic receptor, beta 2)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P18762|reactome:R-MMU-390696|reactome:R-MMU-418555|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-59568N	ensembl:ENSMUSG00000062312(gene)|ensembl:ENSMUST00000058295(transcript)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010008"(endosome membrane)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042060"(wound healing)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|reactome:R-MMU-1227986|reactome:R-MMU-1250196|reactome:R-MMU-1257604|reactome:R-MMU-1963640|reactome:R-MMU-1963642|reactome:R-MMU-416572|reactome:R-MMU-5673001|reactome:R-MMU-6785631|reactome:R-MMU-6811558|reactome:R-MMU-8847993|reactome:R-MMU-8863795|reactome:R-MMU-9652282|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|refseq:NP_001003817.1|dip:DIP-40912N	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:qkANf2gIbjO7PaPMabhawKJORWI10090	rogid:+lOIwIPXJnyC0pwki4J6+7mk1+w10090	rigid:S2479/azJ8VIiOqIpvWDt54CcTA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18762	uniprotkb:P70424	intact:EBI-491143|uniprotkb:Q8BH38|ensembl:ENSMUSP00000062256	intact:EBI-2945468|ensembl:ENSMUSP00000053897|uniprotkb:Q61525|uniprotkb:Q6ZPE0	psi-mi:adrb2_mouse(display_long)|uniprotkb:Beta-2 adrenoreceptor(gene name synonym)|uniprotkb:Adrb2(gene name)|psi-mi:Adrb2(display_short)|uniprotkb:Adrb2r(gene name synonym)	psi-mi:erbb2_mouse(display_long)|uniprotkb:Erbb2(gene name)|psi-mi:Erbb2(display_short)|uniprotkb:Kiaa3023(gene name synonym)|uniprotkb:Neu(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:p185erbB2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Negro et al. (2006)	pubmed:17043217|doi:10.1073/pnas.0607499103|imex:IM-23944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15606200|imex:IM-23944-3|dip:DIP-198158E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005901"(caveola)|refseq:NP_031446.2|ensembl:ENSMUSG00000045730(gene)|ensembl:ENSMUST00000053640(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001993"(regulation of systemic arterial blood pressure by norepinephrine-epinephrine)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002025"(norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002086"(diaphragm contraction)|go:"GO:0003059"(positive regulation of the force of heart contraction by epinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004941"(beta2-adrenergic receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019899"(enzyme binding)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031649"(heat generation)|go:"GO:0031713"(B2 bradykinin receptor binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051380"(norepinephrine binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061885"(positive regulation of mini excitatory postsynaptic potential)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905665"(positive regulation of calcium ion import across plasma membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000332(Adrenergic receptor, beta 2)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P18762|reactome:R-MMU-390696|reactome:R-MMU-418555|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-59568N	ensembl:ENSMUSG00000062312(gene)|ensembl:ENSMUST00000058295(transcript)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010008"(endosome membrane)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042060"(wound healing)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|reactome:R-MMU-1227986|reactome:R-MMU-1250196|reactome:R-MMU-1257604|reactome:R-MMU-1963640|reactome:R-MMU-1963642|reactome:R-MMU-416572|reactome:R-MMU-5673001|reactome:R-MMU-6785631|reactome:R-MMU-6811558|reactome:R-MMU-8847993|reactome:R-MMU-8863795|reactome:R-MMU-9652282|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|refseq:NP_001003817.1|dip:DIP-40912N	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2017/08/05	2017/08/10	rogid:qkANf2gIbjO7PaPMabhawKJORWI10090	rogid:+lOIwIPXJnyC0pwki4J6+7mk1+w10090	rigid:S2479/azJ8VIiOqIpvWDt54CcTA	false	flag tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P18762	uniprotkb:P70424	intact:EBI-491143|uniprotkb:Q8BH38|ensembl:ENSMUSP00000062256	intact:EBI-2945468|ensembl:ENSMUSP00000053897|uniprotkb:Q61525|uniprotkb:Q6ZPE0	psi-mi:adrb2_mouse(display_long)|uniprotkb:Beta-2 adrenoreceptor(gene name synonym)|uniprotkb:Adrb2(gene name)|psi-mi:Adrb2(display_short)|uniprotkb:Adrb2r(gene name synonym)	psi-mi:erbb2_mouse(display_long)|uniprotkb:Erbb2(gene name)|psi-mi:Erbb2(display_short)|uniprotkb:Kiaa3023(gene name synonym)|uniprotkb:Neu(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:p185erbB2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Negro et al. (2006)	pubmed:17043217|doi:10.1073/pnas.0607499103|imex:IM-23944	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15606219|imex:IM-23944-4|dip:DIP-198158E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005901"(caveola)|refseq:NP_031446.2|ensembl:ENSMUSG00000045730(gene)|ensembl:ENSMUST00000053640(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001993"(regulation of systemic arterial blood pressure by norepinephrine-epinephrine)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0002025"(norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0002032"(desensitization of G protein-coupled receptor signaling pathway by arrestin)|go:"GO:0002086"(diaphragm contraction)|go:"GO:0003059"(positive regulation of the force of heart contraction by epinephrine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004941"(beta2-adrenergic receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008306"(associative learning)|go:"GO:0009409"(response to cold)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019899"(enzyme binding)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031649"(heat generation)|go:"GO:0031713"(B2 bradykinin receptor binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042311"(vasodilation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051380"(norepinephrine binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061885"(positive regulation of mini excitatory postsynaptic potential)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901098"(positive regulation of autophagosome maturation)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905665"(positive regulation of calcium ion import across plasma membrane)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000332(Adrenergic receptor, beta 2)|interpro:IPR002233(Adrenergic receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P18762|reactome:R-MMU-390696|reactome:R-MMU-418555|reactome:R-MMU-5689880|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-59568N	ensembl:ENSMUSG00000062312(gene)|ensembl:ENSMUST00000058295(transcript)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010008"(endosome membrane)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042060"(wound healing)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|reactome:R-MMU-1227986|reactome:R-MMU-1250196|reactome:R-MMU-1257604|reactome:R-MMU-1963640|reactome:R-MMU-1963642|reactome:R-MMU-416572|reactome:R-MMU-5673001|reactome:R-MMU-6785631|reactome:R-MMU-6811558|reactome:R-MMU-8847993|reactome:R-MMU-8863795|reactome:R-MMU-9652282|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|refseq:NP_001003817.1|dip:DIP-40912N	psi-mi:"MI:0465"(dip)	caution:This sequence has been withdrawn from Uniprot.	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/05	2017/08/10	rogid:qkANf2gIbjO7PaPMabhawKJORWI10090	rogid:+lOIwIPXJnyC0pwki4J6+7mk1+w10090	rigid:S2479/azJ8VIiOqIpvWDt54CcTA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)