#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q07540 uniprotkb:Q07540 intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name) psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name) psi-mi:"MI:0410"(3D electron microscopy) Karlberg et al. (2006) pubmed:17027502|doi:10.1016/j.str.2006.08.010|imex:IM-8475 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15604461|imex:IM-8475-2|dip:DIP-57165E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding) dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding) psi-mi:"MI:0465"(dip) crc64:AB1FF7478EF0E5D6 crc64:AB1FF7478EF0E5D6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292 rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292 rigid:XZLZDxZ+31o74O2/mIh8n0CC2dg false sufficient binding region:52-174|mutation:73-73 sufficient binding region:52-174|mutation:73-73 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q07540 uniprotkb:Q07540 intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W intact:EBI-2206814|uniprotkb:D6VRN0|ensemblfungi:YDL120W psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name) psi-mi:frda_yeast(display_long)|uniprotkb:YFH1(gene name)|psi-mi:YFH1(display_short)|uniprotkb:YDL120W(locus name) psi-mi:"MI:0114"(x-ray crystallography) Karlberg et al. (2006) pubmed:17027502|doi:10.1016/j.str.2006.08.010|imex:IM-8475 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15604482|imex:IM-8475-1|dip:DIP-57165E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding) dip:DIP-7485N|refseq:NP_010163.1|sgd:S000002278|mint:Q07540|ensemblfungi:YDL120W(gene)|ensemblfungi:YDL120W_mRNA(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0006811"(ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008199"(ferric iron binding)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0018283"(iron incorporation into metallo-sulfur cluster)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002908(Frataxin-like)|interpro:IPR017789(Frataxin)|interpro:IPR020895|interpro:IPR036524|rcsb pdb:2FQL|rcsb pdb:2GA5|rcsb pdb:3OEQ|rcsb pdb:3OER|rcsb pdb:4EC2|rcsb pdb:5T0V|rcsb pdb:5TRE|reactome:R-SCE-1268020|reactome:R-SCE-1362409|go:"GO:0008198"(ferrous iron binding) psi-mi:"MI:0465"(dip) crc64:AB1FF7478EF0E5D6 crc64:AB1FF7478EF0E5D6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/05 2017/08/10 rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292 rogid:4UcroTodEXb/5+xHGpnXDXf/rd8559292 rigid:XZLZDxZ+31o74O2/mIh8n0CC2dg false sufficient binding region:52-174|mutation:73-73 sufficient binding region:52-174|mutation:73-73 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)