#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P33148 uniprotkb:P33148 intact:EBI-15603953|uniprotkb:Q91543 intact:EBI-15603953|uniprotkb:Q91543 psi-mi:cadhf_xenla(display_long)|uniprotkb:C-cadherin(gene name synonym) psi-mi:cadhf_xenla(display_long)|uniprotkb:C-cadherin(gene name synonym) psi-mi:"MI:0859"(force spectroscopy) Prakasam et al. (2006) pubmed:17023539|doi:10.1073/pnas.0606701103|imex:IM-23933 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15603974|imex:IM-23933-1|dip:DIP-198125E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|rcsb pdb:1L3W|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|refseq:NP_001080946.1|dip:DIP-59585N go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|rcsb pdb:1L3W|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|refseq:NP_001080946.1|dip:DIP-59585N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:9lcrivr/gKOFy7upxvFxqjQZIHQ8355 rogid:9lcrivr/gKOFy7upxvFxqjQZIHQ8355 rigid:LsTmb8kALKH1EsW7Sf6yGuq4/oQ false sufficient binding region:156-704 sufficient binding region:156-704 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P33148 uniprotkb:P10288 intact:EBI-15603953|uniprotkb:Q91543 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 psi-mi:cadhf_xenla(display_long)|uniprotkb:C-cadherin(gene name synonym) psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:"MI:0859"(force spectroscopy) Prakasam et al. (2006) pubmed:17023539|doi:10.1073/pnas.0606701103|imex:IM-23933 taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15604066|imex:IM-23933-3|dip:DIP-198130E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|rcsb pdb:1L3W|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|refseq:NP_001080946.1|dip:DIP-59585N ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:9lcrivr/gKOFy7upxvFxqjQZIHQ8355 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rigid:bxCk2rUdxbgv8Um78ehIxagIocc false sufficient binding region:156-704 sufficient binding region:165-720 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1PAA9 uniprotkb:F1PAA9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:"MI:0859"(force spectroscopy) Prakasam et al. (2006) pubmed:17023539|doi:10.1073/pnas.0606701103|imex:IM-23933 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15604087|imex:IM-23933-4|dip:DIP-198126E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rigid:RTqGpaagfPrSGfER7J0oyrOtyYg false sufficient binding region:158-688 sufficient binding region:158-688 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1PAA9 uniprotkb:P10288 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:"MI:0859"(force spectroscopy) Prakasam et al. (2006) pubmed:17023539|doi:10.1073/pnas.0606701103|imex:IM-23933 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15604105|imex:IM-23933-5|dip:DIP-198129E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rigid:sVrDMpjRsK9Tdc3/TzRG2Ol2ukY false sufficient binding region:158-688 sufficient binding region:165-720 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:F1PAA9 uniprotkb:P33148 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-15603953|uniprotkb:Q91543 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cadhf_xenla(display_long)|uniprotkb:C-cadherin(gene name synonym) psi-mi:"MI:0859"(force spectroscopy) Prakasam et al. (2006) pubmed:17023539|doi:10.1073/pnas.0606701103|imex:IM-23933 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15604045|imex:IM-23933-2|dip:DIP-198128E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016021"(integral component of membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR020894|interpro:IPR027397|interpro:IPR039808|rcsb pdb:1L3W|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|refseq:NP_001080946.1|dip:DIP-59585N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:9lcrivr/gKOFy7upxvFxqjQZIHQ8355 rigid:2hs8LozCzEOE6JAiJdaEVh0pSws false sufficient binding region:158-688 sufficient binding region:156-704 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10288 uniprotkb:P10288 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 intact:EBI-985728|uniprotkb:Q90630|ensembl:ENSGALP00000024371 psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:cadh2_chick(display_long)|uniprotkb:Neural cadherin(gene name synonym)|uniprotkb:CDH2(gene name)|psi-mi:CDH2(display_short) psi-mi:"MI:0859"(force spectroscopy) Prakasam et al. (2006) pubmed:17023539|doi:10.1073/pnas.0606701103|imex:IM-23933 taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") taxid:9031(chick)|taxid:9031("Gallus gallus (Chicken)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15604126|imex:IM-23933-6|dip:DIP-198127E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N ensembl:ENSGALG00000015132(gene)|ensembl:ENSGALT00000024417(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001841"(neural tube formation)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0007416"(synapse assembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0009986"(cell surface)|go:"GO:0036032"(neural crest cell delamination)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060563"(neuroepithelial cell differentiation)|go:"GO:0061561"(trigeminal ganglion formation)|go:"GO:0061563"(trigeminal ganglion structural organization)|go:"GO:0014032"(neural crest cell development)|go:"GO:0070445"(regulation of oligodendrocyte progenitor proliferation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090497"(mesenchymal cell migration)|go:"GO:0097118"(neuroligin clustering involved in postsynaptic membrane assembly)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098743"(cell aggregation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099060"(integral component of postsynaptic specialization membrane)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030051|interpro:IPR039808|mint:P10288|reactome:R-GGA-381426|reactome:R-GGA-418990|reactome:R-GGA-525793|reactome:R-GGA-8957275|go:"GO:0099055"(integral component of postsynaptic membrane)|refseq:NP_001001615.1|dip:DIP-29636N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rogid:G2ilNbqT7TXetNYV/YvjwvReo8Q9031 rigid:/deJfVkiiIqET0Bs3ZbLHcLqGRQ false sufficient binding region:165-720 sufficient binding region:165-720 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)