#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P34162	uniprotkb:P32585	intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym)	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600187|imex:IM-8574-1|dip:DIP-18289E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585	psi-mi:"MI:0465"(dip)	crc64:C30BF309D43AFB2A	crc64:B1148FC187C2802A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	rigid:0uCd6brmoLZHw30g/Ez+dm3l3Ro	false	-	sufficient binding region:141-307,1-108|experimental feature:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38304	uniprotkb:P34162	intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C	intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C	psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)	psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600209|imex:IM-8574-5|dip:DIP-57256E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N	refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162	psi-mi:"MI:0465"(dip)	crc64:86B2A064293C6B61	crc64:C30BF309D43AFB2A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:UdED273ourIyAm1t31wIqC/kKX8559292	rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292	rigid:CxLmWimV5lHK50NhGl5FXZceVCM	false	sufficient binding region:190-210|his tag:c-c	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38304	uniprotkb:P32585	intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600209|imex:IM-8574-5|dip:DIP-57256E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585	psi-mi:"MI:0465"(dip)	crc64:86B2A064293C6B61	crc64:B1148FC187C2802A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:UdED273ourIyAm1t31wIqC/kKX8559292	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	rigid:CxLmWimV5lHK50NhGl5FXZceVCM	false	sufficient binding region:190-210|his tag:c-c	sufficient binding region:141-307,1-108	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32585	uniprotkb:P34162	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600235|imex:IM-8574-2|dip:DIP-57256E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585	refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162	psi-mi:"MI:0465"(dip)	crc64:B1148FC187C2802A	crc64:C30BF309D43AFB2A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292	rigid:CxLmWimV5lHK50NhGl5FXZceVCM	false	sufficient binding region:141-307,1-108	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32585	uniprotkb:P38304	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600235|imex:IM-8574-2|dip:DIP-57256E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585	refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N	psi-mi:"MI:0465"(dip)	crc64:B1148FC187C2802A	crc64:86B2A064293C6B61	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	rogid:UdED273ourIyAm1t31wIqC/kKX8559292	rigid:CxLmWimV5lHK50NhGl5FXZceVCM	false	sufficient binding region:141-307,1-108	sufficient binding region:190-210|his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13393	uniprotkb:P34162	intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W	intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C	psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600260|imex:IM-8574-6|dip:DIP-57257E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393	refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162	psi-mi:"MI:0465"(dip)	crc64:50365FFF1D3718CE	crc64:C30BF309D43AFB2A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292	rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292	rigid:dNIZYlGyfivk57rtPUJbsb7nV5s	false	his tag:c-c	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P13393	uniprotkb:P32585	intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600260|imex:IM-8574-6|dip:DIP-57257E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585	psi-mi:"MI:0465"(dip)	crc64:50365FFF1D3718CE	crc64:B1148FC187C2802A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	rigid:dNIZYlGyfivk57rtPUJbsb7nV5s	false	his tag:c-c	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P13393	uniprotkb:P38304	intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W	intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C	psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600260|imex:IM-8574-6|dip:DIP-57257E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393	refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N	psi-mi:"MI:0465"(dip)	crc64:50365FFF1D3718CE	crc64:86B2A064293C6B61	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292	rogid:UdED273ourIyAm1t31wIqC/kKX8559292	rigid:dNIZYlGyfivk57rtPUJbsb7nV5s	false	his tag:c-c	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P13393	uniprotkb:P38304	intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W	intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C	psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600281|imex:IM-8574-8|dip:DIP-57258E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393	refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N	psi-mi:"MI:0465"(dip)	crc64:50365FFF1D3718CE	crc64:86B2A064293C6B61	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292	rogid:UdED273ourIyAm1t31wIqC/kKX8559292	rigid:BTpT/JJHUC0MdKx0nonSzED5nd0	false	his tag:c-c	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:P20433	uniprotkb:P34087	intact:EBI-15777|ensemblfungi:YJL140W|uniprotkb:D6VW44	intact:EBI-15790|uniprotkb:D6VT36|ensemblfungi:YDR404C	psi-mi:rpb4_yeast(display_long)|uniprotkb:RPB4(gene name)|psi-mi:RPB4(display_short)|uniprotkb:YJL140W(locus name)|uniprotkb:J0654(orf name)|uniprotkb:DNA-directed RNA polymerase II 32 kDa polypeptide(gene name synonym)|uniprotkb:B32(gene name synonym)	psi-mi:rpb7_yeast(display_long)|uniprotkb:RPB7(gene name)|psi-mi:RPB7(display_short)|uniprotkb:YDR404C(locus name)|uniprotkb:D9509.22(orf name)|uniprotkb:B16(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600321|imex:IM-8574-7|dip:DIP-715E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005634"(nucleus)|ensemblfungi:YJL140W(gene)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|ensemblfungi:YJL140W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|rcsb pdb:1NT9|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|rcsb pdb:1PQV|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63|rcsb pdb:2B8K|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:4BY7|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|refseq:NP_012395.1|sgd:S000003676|dip:DIP-55N|mint:P20433	sgd:S000002812|refseq:NP_010692.3|dip:DIP-725N|mint:P34087|rcsb pdb:2JA5|rcsb pdb:2JA6|rcsb pdb:2JA7|rcsb pdb:2JA8|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:3FKI|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C3E|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4X|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6I84|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O4K|rcsb pdb:7O4L|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-77075|reactome:R-SCE-9018519|rcsb pdb:2B8K|ensemblfungi:YDR404C(gene)|ensemblfungi:YDR404C_mRNA(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1WCM|rcsb pdb:1Y14|rcsb pdb:1Y1V|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|rcsb pdb:2B63	psi-mi:"MI:0465"(dip)	crc64:72A8A26871B87775	crc64:44C85603A93CDE67	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:8FcFNl5l+wzofN6xEPZv184Zc1E559292	rogid:Q+VUnkG9LhmQRZNmkFSdmcNozjE559292	rigid:h8klCPbdzNzlxCPPMt6YKFlEIc4	false	-	his tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13393	uniprotkb:P38304	intact:EBI-19129|uniprotkb:D3DM55|ensemblfungi:YER148W	intact:EBI-20932|uniprotkb:D6VQI7|ensemblfungi:YBR193C	psi-mi:tbp_yeast(display_long)|uniprotkb:YER148W(locus name)|uniprotkb:SPT15(gene name)|psi-mi:SPT15(display_short)|uniprotkb:BTF1(gene name synonym)|uniprotkb:TBP1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription factor D(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:med8_yeast(display_long)|uniprotkb:YBR193C(locus name)|uniprotkb:YBR1403(orf name)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600300|imex:IM-8574-3|dip:DIP-57258E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000000950|ensemblfungi:YER148W(gene)|ensemblfungi:YER148W_mRNA(transcript)|go:"GO:0000126"(transcription factor TFIIIB complex)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0001092"(TFIIA-class transcription factor complex binding)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070893"(transposon integration)|go:"GO:0070898"(RNA polymerase III preinitiation complex assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|rcsb pdb:1NGM|rcsb pdb:1NH2|rcsb pdb:1RM1|rcsb pdb:1TBA|rcsb pdb:1TBP|rcsb pdb:1YTB|rcsb pdb:1YTF|rcsb pdb:4B0A|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5SVA|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6E16|rcsb pdb:6E24|rcsb pdb:6EU0|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6TBM|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-674695|reactome:R-SCE-6807505|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-9018519|refseq:NP_011075.3|dip:DIP-44N|mint:P13393	refseq:NP_009752.3|sgd:S000000397|mint:P38304|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|ensemblfungi:YBR193C(gene)|ensemblfungi:YBR193C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|rcsb pdb:2HZS|rcsb pdb:3J1O|dip:DIP-1659N	psi-mi:"MI:0465"(dip)	crc64:50365FFF1D3718CE	crc64:86B2A064293C6B61	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:fVZPztzKW8tuxDYYpZ7ZTFlq3Do559292	rogid:UdED273ourIyAm1t31wIqC/kKX8559292	rigid:BTpT/JJHUC0MdKx0nonSzED5nd0	false	his tag:c-c	sufficient binding region:1-138	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P34162	uniprotkb:P32585	intact:EBI-18018|uniprotkb:D3DKY9|ensemblfungi:YHR041C	intact:EBI-18032|uniprotkb:D6VUN6|uniprotkb:Q6B1R3|ensemblfungi:YGR104C	psi-mi:med20_yeast(display_long)|uniprotkb:YHR041C(locus name)|uniprotkb:SRB2(gene name)|psi-mi:SRB2(display_short)|uniprotkb:HRS2(gene name synonym)|uniprotkb:MED20(gene name synonym)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 2(gene name synonym)|uniprotkb:Hyper-recombination suppressor protein 2(gene name synonym)	psi-mi:med18_yeast(display_long)|uniprotkb:YGR104C(locus name)|uniprotkb:SRB5(gene name)|psi-mi:SRB5(display_short)|uniprotkb:MED18(gene name synonym)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:Suppressor of RNA polymerase B 5(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Larivière et al. (2006)	pubmed:16964259|doi:10.1038/nsmb1143|imex:IM-8574	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15600341|imex:IM-8574-4|dip:DIP-18289E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011907.1|sgd:S000001083|ensemblfungi:YHR041C(gene)|ensemblfungi:YHR041C_mRNA(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010689"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0016592"(mediator complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR013921(TATA-binding related factor)|interpro:IPR016532(Mediator complex, subunit 20)|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|dip:DIP-107N|mint:P34162	sgd:S000003336|ensemblfungi:YGR104C(gene)|ensemblfungi:YGR104C_mRNA(transcript)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|rcsb pdb:2HZM|rcsb pdb:2HZS|rcsb pdb:3J1O|rcsb pdb:3RJ1|rcsb pdb:4GWP|rcsb pdb:4GWQ|rcsb pdb:4V1O|rcsb pdb:5OQM|rcsb pdb:5SVA|go:"GO:0001113"(transcription open complex formation at RNA polymerase II promoter)|refseq:NP_011618.3|dip:DIP-1658N|mint:P32585	psi-mi:"MI:0465"(dip)	crc64:C30BF309D43AFB2A	crc64:B1148FC187C2802A	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/05	2017/08/10	rogid:D2Zs1KYyPj3RbDQC4fz/XtWL+s0559292	rogid:+/qC0affGDlvusbTV43B3aCgZBU559292	rigid:0uCd6brmoLZHw30g/Ez+dm3l3Ro	false	-	sufficient binding region:141-307,1-108	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)