#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P10823 uniprotkb:P08678 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-5364|uniprotkb:D6VWH0|ensemblfungi:YJL005W psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:cyaa_yeast(display_long)|uniprotkb:CYR1(gene name)|psi-mi:CYR1(display_short)|uniprotkb:CDC35(gene name synonym)|uniprotkb:HSR1(gene name synonym)|uniprotkb:SRA4(gene name synonym)|uniprotkb:YJL005W(locus name)|uniprotkb:J1401(orf name)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598117|imex:IM-23889-1|dip:DIP-198025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 sgd:S000003542|refseq:NP_012529.3|dip:DIP-2317N|mint:P08678|ensemblfungi:YJL005W(gene)|ensemblfungi:YJL005W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016791"(phosphatase activity)|interpro:IPR000159(Ras-association)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013716(Adenylate cyclase G-alpha binding)|interpro:IPR029787|interpro:IPR032675|interpro:IPR036457|reactome:R-SCE-199418|reactome:R-SCE-5223345 psi-mi:"MI:0465"(dip) crc64:881B91792AE91748 crc64:BEAB7419AB6989D0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:jcjdcDnCxKuonhXVJ9cUa6cAiwA559292 rigid:rO8rX23ghonOqOyBaC8cIpHkbRw false glutathione s tranferase tag:n-n ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05986 uniprotkb:P39717 intact:EBI-9470|ensemblfungi:YKL166C|uniprotkb:D6VX33 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W psi-mi:kapc_yeast(display_long)|uniprotkb:TPK3(gene name)|psi-mi:TPK3(display_short)|uniprotkb:PKA3(gene name synonym)|uniprotkb:YKL166C(locus name)|uniprotkb:YKL630(orf name) psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598159|imex:IM-23889-3|dip:DIP-198028E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YKL166C(gene)|ensemblfungi:YKL166C_mRNA(transcript)|go:"GO:0000932"(P-body)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_012755.1|sgd:S000001649|dip:DIP-550N refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N psi-mi:"MI:0465"(dip) crc64:4ADDE8E63032B313 crc64:343627001C52020E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:M88Xnp3RLgwjxuyiYku9TvqedCI559292 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rigid:ivkQdi4DtH1U9TMiKhqSoCo6qkc false glutathione s tranferase tag:n-n ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P08678 uniprotkb:P10823 intact:EBI-5364|uniprotkb:D6VWH0|ensemblfungi:YJL005W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:cyaa_yeast(display_long)|uniprotkb:CYR1(gene name)|psi-mi:CYR1(display_short)|uniprotkb:CDC35(gene name synonym)|uniprotkb:HSR1(gene name synonym)|uniprotkb:SRA4(gene name synonym)|uniprotkb:YJL005W(locus name)|uniprotkb:J1401(orf name)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598138|imex:IM-23889-2|dip:DIP-198025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003542|refseq:NP_012529.3|dip:DIP-2317N|mint:P08678|ensemblfungi:YJL005W(gene)|ensemblfungi:YJL005W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016791"(phosphatase activity)|interpro:IPR000159(Ras-association)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013716(Adenylate cyclase G-alpha binding)|interpro:IPR029787|interpro:IPR032675|interpro:IPR036457|reactome:R-SCE-199418|reactome:R-SCE-5223345 sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0465"(dip) crc64:BEAB7419AB6989D0 crc64:881B91792AE91748 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:jcjdcDnCxKuonhXVJ9cUa6cAiwA559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rigid:rO8rX23ghonOqOyBaC8cIpHkbRw false ha tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P05132 uniprotkb:P39717 intact:EBI-400564|uniprotkb:Q9JID0|ensembl:ENSMUSP00000005606 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W psi-mi:kapca_mouse(display_long)|uniprotkb:Prkaca(gene name)|psi-mi:Prkaca(display_short)|uniprotkb:Pkaca(gene name synonym) psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598180|imex:IM-23889-4|dip:DIP-198029E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001264827.1|refseq:NP_032880.1|reactome:R-MMU-8963896|reactome:R-MMU-983231|ensembl:ENSMUSG00000005469(gene)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P05132|ensembl:ENSMUST00000005606(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048792"(spontaneous exocytosis of neurotransmitter)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097225"(sperm midpiece)|rcsb pdb:1APM|rcsb pdb:1ATP|rcsb pdb:1BKX|rcsb pdb:1BX6|rcsb pdb:1FMO|rcsb pdb:1J3H|rcsb pdb:1JBP|rcsb pdb:1JLU|rcsb pdb:1L3R|rcsb pdb:1PVK|rcsb pdb:1RDQ|rcsb pdb:1RE8|rcsb pdb:1REJ|rcsb pdb:1REK|rcsb pdb:1SYK|rcsb pdb:2CPK|rcsb pdb:2ERZ|rcsb pdb:2QCS|rcsb pdb:2QUR|rcsb pdb:2QVS|rcsb pdb:3FHI|rcsb pdb:3FJQ|rcsb pdb:3IDB|rcsb pdb:3IDC|rcsb pdb:3J4Q|rcsb pdb:3J4R|rcsb pdb:3O7L|rcsb pdb:3OW3|rcsb pdb:3PVB|rcsb pdb:3QAL|rcsb pdb:3QAM|rcsb pdb:3TNP|rcsb pdb:3TNQ|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4DFX|rcsb pdb:4DFY|rcsb pdb:4DFZ|rcsb pdb:4DG0|rcsb pdb:4DG2|rcsb pdb:4DG3|rcsb pdb:4DH1|rcsb pdb:4DH3|rcsb pdb:4DH5|rcsb pdb:4DH7|rcsb pdb:4DH8|rcsb pdb:4DIN|rcsb pdb:4HPT|rcsb pdb:4HPU|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4NTS|rcsb pdb:4NTT|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4WBB|rcsb pdb:4X6Q|rcsb pdb:4X6R|rcsb pdb:4XW4|rcsb pdb:4XW5|rcsb pdb:4XW6|rcsb pdb:5JR7|rcsb pdb:5X3F|rcsb pdb:6E21|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|rcsb pdb:6MM8|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-381676|reactome:R-MMU-392517|reactome:R-MMU-422356|reactome:R-MMU-432040|reactome:R-MMU-4420097|reactome:R-MMU-442720|reactome:R-MMU-512988|reactome:R-MMU-5578775|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5620912|reactome:R-MMU-5621575|reactome:R-MMU-5687128|reactome:R-MMU-8853659|reactome:R-MMU-8854518|dip:DIP-6086N refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N psi-mi:"MI:0465"(dip) - crc64:343627001C52020E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:HdW51RuiujpUxo0Fu8TbWz3Yk8c10090 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rigid:u+QK0GgwERreaBkRH2oo9sCMXxo false glutathione s tranferase tag:n-n ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39717 uniprotkb:P10823 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598201|imex:IM-23889-5|dip:DIP-18271E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0465"(dip) crc64:343627001C52020E crc64:881B91792AE91748 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rigid:9lgfDvGqJcVIIFBVT2jaDrb9A+s false ha tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P39717 uniprotkb:P10823 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598222|imex:IM-23889-6|dip:DIP-18271E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0465"(dip) crc64:343627001C52020E crc64:881B91792AE91748 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rigid:9lgfDvGqJcVIIFBVT2jaDrb9A+s false ha tag:c-c glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P06244 uniprotkb:P39717 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598243|imex:IM-23889-7|dip:DIP-198026E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N psi-mi:"MI:0465"(dip) crc64:D4E5C30D7F11458B crc64:343627001C52020E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rigid:t7lnUaUmIcMRQsVjiLd/U2w6K8o false his tag:n-n ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P05132 uniprotkb:P39717 intact:EBI-400564|uniprotkb:Q9JID0|ensembl:ENSMUSP00000005606 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W psi-mi:kapca_mouse(display_long)|uniprotkb:Prkaca(gene name)|psi-mi:Prkaca(display_short)|uniprotkb:Pkaca(gene name synonym) psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15598264|imex:IM-23889-8|dip:DIP-198029E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001264827.1|refseq:NP_032880.1|reactome:R-MMU-8963896|reactome:R-MMU-983231|ensembl:ENSMUSG00000005469(gene)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P05132|ensembl:ENSMUST00000005606(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048792"(spontaneous exocytosis of neurotransmitter)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097225"(sperm midpiece)|rcsb pdb:1APM|rcsb pdb:1ATP|rcsb pdb:1BKX|rcsb pdb:1BX6|rcsb pdb:1FMO|rcsb pdb:1J3H|rcsb pdb:1JBP|rcsb pdb:1JLU|rcsb pdb:1L3R|rcsb pdb:1PVK|rcsb pdb:1RDQ|rcsb pdb:1RE8|rcsb pdb:1REJ|rcsb pdb:1REK|rcsb pdb:1SYK|rcsb pdb:2CPK|rcsb pdb:2ERZ|rcsb pdb:2QCS|rcsb pdb:2QUR|rcsb pdb:2QVS|rcsb pdb:3FHI|rcsb pdb:3FJQ|rcsb pdb:3IDB|rcsb pdb:3IDC|rcsb pdb:3J4Q|rcsb pdb:3J4R|rcsb pdb:3O7L|rcsb pdb:3OW3|rcsb pdb:3PVB|rcsb pdb:3QAL|rcsb pdb:3QAM|rcsb pdb:3TNP|rcsb pdb:3TNQ|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4DFX|rcsb pdb:4DFY|rcsb pdb:4DFZ|rcsb pdb:4DG0|rcsb pdb:4DG2|rcsb pdb:4DG3|rcsb pdb:4DH1|rcsb pdb:4DH3|rcsb pdb:4DH5|rcsb pdb:4DH7|rcsb pdb:4DH8|rcsb pdb:4DIN|rcsb pdb:4HPT|rcsb pdb:4HPU|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4NTS|rcsb pdb:4NTT|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4WBB|rcsb pdb:4X6Q|rcsb pdb:4X6R|rcsb pdb:4XW4|rcsb pdb:4XW5|rcsb pdb:4XW6|rcsb pdb:5JR7|rcsb pdb:5X3F|rcsb pdb:6E21|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|rcsb pdb:6MM8|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-381676|reactome:R-MMU-392517|reactome:R-MMU-422356|reactome:R-MMU-432040|reactome:R-MMU-4420097|reactome:R-MMU-442720|reactome:R-MMU-512988|reactome:R-MMU-5578775|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5620912|reactome:R-MMU-5621575|reactome:R-MMU-5687128|reactome:R-MMU-8853659|reactome:R-MMU-8854518|dip:DIP-6086N refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N psi-mi:"MI:0465"(dip) - crc64:343627001C52020E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:HdW51RuiujpUxo0Fu8TbWz3Yk8c10090 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rigid:u+QK0GgwERreaBkRH2oo9sCMXxo false glutathione s tranferase tag:n-n his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06244 uniprotkb:P39717 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598285|imex:IM-23889-9|dip:DIP-198026E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N psi-mi:"MI:0465"(dip) crc64:D4E5C30D7F11458B crc64:343627001C52020E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rigid:t7lnUaUmIcMRQsVjiLd/U2w6K8o false glutathione s tranferase tag:n-n ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P39717 uniprotkb:P10823 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598306|imex:IM-23889-10|dip:DIP-18271E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 psi-mi:"MI:0465"(dip) crc64:343627001C52020E crc64:881B91792AE91748 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rigid:9lgfDvGqJcVIIFBVT2jaDrb9A+s false his tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P06244 uniprotkb:P39717 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598389|imex:IM-23889-14|dip:DIP-198026E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N psi-mi:"MI:0465"(dip) crc64:D4E5C30D7F11458B crc64:343627001C52020E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rigid:t7lnUaUmIcMRQsVjiLd/U2w6K8o false glutathione s tranferase tag:n-n his tag:n-n|sufficient binding region:1-275 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P06245 uniprotkb:P39717 intact:EBI-9465|ensemblfungi:YPL203W|uniprotkb:D6W3G6 intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W psi-mi:kapb_yeast(display_long)|uniprotkb:YPL203W(locus name)|uniprotkb:TPK2(gene name)|psi-mi:TPK2(display_short)|uniprotkb:PKA2(gene name synonym)|uniprotkb:YKR1(gene name synonym) psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598368|imex:IM-23889-13|dip:DIP-198027E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YPL203W(gene)|ensemblfungi:YPL203W_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000932"(P-body)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000766"(negative regulation of cytoplasmic translation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|refseq:NP_015121.1|sgd:S000006124|mint:P06245|dip:DIP-549N refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N psi-mi:"MI:0465"(dip) crc64:1BC255C6D0F33137 crc64:343627001C52020E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:9Lh+GL9j37UYnEst/qBIiSKPMd4559292 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rigid:17Dq6Z/OMuKZQVzEKnKkxnzDE2s false glutathione s tranferase tag:n-n ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9DBC7 uniprotkb:P05132 intact:EBI-645677|uniprotkb:Q3UKU7|uniprotkb:Q9JHR5|uniprotkb:Q9JHR6|ensembl:ENSMUSP00000056500|ensembl:ENSMUSP00000102288 intact:EBI-400564|uniprotkb:Q9JID0|ensembl:ENSMUSP00000005606 psi-mi:kap0_mouse(display_long)|uniprotkb:Prkar1a(gene name)|psi-mi:Prkar1a(display_short) psi-mi:kapca_mouse(display_long)|uniprotkb:Prkaca(gene name)|psi-mi:Prkaca(display_short)|uniprotkb:Pkaca(gene name synonym) psi-mi:"MI:0018"(two hybrid) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598351|imex:IM-23889-12|dip:DIP-198030E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300902.1|refseq:NP_001300903.1|refseq:NP_001300904.1|refseq:NP_001300905.1|refseq:NP_068680.1|refseq:XP_017169829.1|dip:DIP-32450N|ensembl:ENSMUSG00000020612(gene)|ensembl:ENSMUST00000049527(transcript)|ensembl:ENSMUST00000106677(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007507"(heart development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|reactome:R-MMU-983231|reactome:R-MMU-5610787|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:Q9DBC7|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-432040|go:"GO:0043949"(regulation of cAMP-mediated signaling)|reactome:R-MMU-442720 refseq:NP_001264827.1|refseq:NP_032880.1|reactome:R-MMU-8963896|reactome:R-MMU-983231|ensembl:ENSMUSG00000005469(gene)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|mint:P05132|ensembl:ENSMUST00000005606(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048792"(spontaneous exocytosis of neurotransmitter)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097225"(sperm midpiece)|rcsb pdb:1APM|rcsb pdb:1ATP|rcsb pdb:1BKX|rcsb pdb:1BX6|rcsb pdb:1FMO|rcsb pdb:1J3H|rcsb pdb:1JBP|rcsb pdb:1JLU|rcsb pdb:1L3R|rcsb pdb:1PVK|rcsb pdb:1RDQ|rcsb pdb:1RE8|rcsb pdb:1REJ|rcsb pdb:1REK|rcsb pdb:1SYK|rcsb pdb:2CPK|rcsb pdb:2ERZ|rcsb pdb:2QCS|rcsb pdb:2QUR|rcsb pdb:2QVS|rcsb pdb:3FHI|rcsb pdb:3FJQ|rcsb pdb:3IDB|rcsb pdb:3IDC|rcsb pdb:3J4Q|rcsb pdb:3J4R|rcsb pdb:3O7L|rcsb pdb:3OW3|rcsb pdb:3PVB|rcsb pdb:3QAL|rcsb pdb:3QAM|rcsb pdb:3TNP|rcsb pdb:3TNQ|rcsb pdb:3X2U|rcsb pdb:3X2V|rcsb pdb:3X2W|rcsb pdb:4DFX|rcsb pdb:4DFY|rcsb pdb:4DFZ|rcsb pdb:4DG0|rcsb pdb:4DG2|rcsb pdb:4DG3|rcsb pdb:4DH1|rcsb pdb:4DH3|rcsb pdb:4DH5|rcsb pdb:4DH7|rcsb pdb:4DH8|rcsb pdb:4DIN|rcsb pdb:4HPT|rcsb pdb:4HPU|rcsb pdb:4IAC|rcsb pdb:4IAD|rcsb pdb:4IAF|rcsb pdb:4IAI|rcsb pdb:4IAK|rcsb pdb:4IAY|rcsb pdb:4IAZ|rcsb pdb:4IB0|rcsb pdb:4IB1|rcsb pdb:4IB3|rcsb pdb:4NTS|rcsb pdb:4NTT|rcsb pdb:4O21|rcsb pdb:4O22|rcsb pdb:4WBB|rcsb pdb:4X6Q|rcsb pdb:4X6R|rcsb pdb:4XW4|rcsb pdb:4XW5|rcsb pdb:4XW6|rcsb pdb:5JR7|rcsb pdb:5X3F|rcsb pdb:6E21|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|rcsb pdb:6MM8|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-381676|reactome:R-MMU-392517|reactome:R-MMU-422356|reactome:R-MMU-432040|reactome:R-MMU-4420097|reactome:R-MMU-442720|reactome:R-MMU-512988|reactome:R-MMU-5578775|reactome:R-MMU-5610785|reactome:R-MMU-5610787|reactome:R-MMU-5620912|reactome:R-MMU-5621575|reactome:R-MMU-5687128|reactome:R-MMU-8853659|reactome:R-MMU-8854518|dip:DIP-6086N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:0KqlQxZjK8QfS6VPEiTDtvHNTj410090 rogid:HdW51RuiujpUxo0Fu8TbWz3Yk8c10090 rigid:ypbplTILjsrNOLXtz0AZMMSYG6E false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10823 uniprotkb:P39717 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-20711|uniprotkb:P39716|uniprotkb:D6VPG2|ensemblfungi:YAL056W psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:gpb2_yeast(display_long)|uniprotkb:YAL056W(locus name)|uniprotkb:GPB2(gene name)|psi-mi:GPB2(display_short)|uniprotkb:KRH1(gene name synonym)|uniprotkb:Gbeta mimic kelch protein 2(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15598327|imex:IM-23889-11|dip:DIP-198031E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 refseq:NP_009345.3|sgd:S000000052|ensemblfungi:YAL056W(gene)|ensemblfungi:YAL056W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0030437"(ascospore formation)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0051285"(cell cortex of cell tip)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|dip:DIP-7315N psi-mi:"MI:0465"(dip) crc64:881B91792AE91748 crc64:343627001C52020E full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:UzRvHG5EeNVdJSdozHyMvrupB+s559292 rigid:CEKP1Cotwju1IrpkQ3BpAQO7pCA false glutathione s tranferase tag:n-n ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P10823 uniprotkb:P08678 intact:EBI-7382|uniprotkb:D3DLR9|ensemblfungi:YER020W intact:EBI-5364|uniprotkb:D6VWH0|ensemblfungi:YJL005W psi-mi:gpa2_yeast(display_long)|uniprotkb:YER020W(locus name)|uniprotkb:GPA2(gene name)|psi-mi:GPA2(display_short)|uniprotkb:SSP101(gene name synonym)|uniprotkb:GP2-alpha(gene name synonym) psi-mi:cyaa_yeast(display_long)|uniprotkb:CYR1(gene name)|psi-mi:CYR1(display_short)|uniprotkb:CDC35(gene name synonym)|uniprotkb:HSR1(gene name synonym)|uniprotkb:SRA4(gene name synonym)|uniprotkb:YJL005W(locus name)|uniprotkb:J1401(orf name)|uniprotkb:Adenylyl cyclase(gene name synonym)|uniprotkb:ATP pyrophosphate-lyase(gene name synonym) psi-mi:"MI:0096"(pull down) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15598327|imex:IM-23889-11|dip:DIP-198031E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000822|refseq:NP_010937.3|mint:P10823|dip:DIP-4346N|ensemblfungi:YER020W(gene)|ensemblfungi:YER020W_mRNA(transcript)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007124"(pseudohyphal growth)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009757"(hexose mediated signaling)|go:"GO:0010255"(glucose mediated signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0030437"(ascospore formation)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR002975(Fungal G-protein, alpha subunit)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-SCE-112043|reactome:R-SCE-202040|reactome:R-SCE-399997|reactome:R-SCE-416476|reactome:R-SCE-416482|reactome:R-SCE-418592|reactome:R-SCE-434316|reactome:R-SCE-9013148 sgd:S000003542|refseq:NP_012529.3|dip:DIP-2317N|mint:P08678|ensemblfungi:YJL005W(gene)|ensemblfungi:YJL005W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0016791"(phosphatase activity)|interpro:IPR000159(Ras-association)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR013716(Adenylate cyclase G-alpha binding)|interpro:IPR029787|interpro:IPR032675|interpro:IPR036457|reactome:R-SCE-199418|reactome:R-SCE-5223345 psi-mi:"MI:0465"(dip) crc64:881B91792AE91748 crc64:BEAB7419AB6989D0 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ujQYVD/yCqR8/T2eRPygiuTD7Jg559292 rogid:jcjdcDnCxKuonhXVJ9cUa6cAiwA559292 rigid:CEKP1Cotwju1IrpkQ3BpAQO7pCA false glutathione s tranferase tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P07278 uniprotkb:P06244 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:"MI:0018"(two hybrid) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598412|imex:IM-23889-15|dip:DIP-244E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N psi-mi:"MI:0465"(dip) crc64:6D7D97D8E4340AF3 crc64:D4E5C30D7F11458B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rigid:mO7CjOSmIKTPpek/bK7RV0LjnHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07278 uniprotkb:P06244 intact:EBI-9475|ensemblfungi:YIL033C|uniprotkb:D6VVP9 intact:EBI-9458|uniprotkb:P11595|ensemblfungi:YJL164C|uniprotkb:D6VW23|uniprotkb:Q2VQW1 psi-mi:kapr_yeast(display_long)|uniprotkb:YIL033C(locus name)|uniprotkb:BCY1(gene name)|psi-mi:BCY1(display_short)|uniprotkb:REG1(gene name synonym)|uniprotkb:SRA1(gene name synonym)|uniprotkb:Bypass of cyclase mutations protein 1(gene name synonym)|uniprotkb:Protein kinase A regulatory subunit(gene name synonym) psi-mi:kapa_yeast(display_long)|uniprotkb:TPK1(gene name)|psi-mi:TPK1(display_short)|uniprotkb:PKA1(gene name synonym)|uniprotkb:SRA3(gene name synonym)|uniprotkb:YJL164C(locus name)|uniprotkb:J0541(orf name)|uniprotkb:CDC25-suppressing protein kinase(gene name synonym)|uniprotkb:PK-25(gene name synonym) psi-mi:"MI:0018"(two hybrid) Peeters et al. (2006) pubmed:16924114|doi:10.1073/pnas.0509644103|imex:IM-23889 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15598429|imex:IM-23889-16|dip:DIP-244E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YIL033C(gene)|ensemblfungi:YIL033C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0061406"(positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation)|go:"GO:0097271"(protein localization to bud neck)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|rcsb pdb:3OF1|rcsb pdb:6XQK|refseq:NP_012231.1|sgd:S000001295|mint:P07278|dip:DIP-551N go:"GO:0000785"(chromatin)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010607"(negative regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0051301"(cell division)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:1FOT|ensemblfungi:YJL164C(gene)|ensemblfungi:YJL164C_mRNA(transcript)|refseq:NP_012371.2|sgd:S000003700|mint:P06244|dip:DIP-548N psi-mi:"MI:0465"(dip) crc64:6D7D97D8E4340AF3 crc64:D4E5C30D7F11458B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/05 2017/08/10 rogid:rSJ37UFoFiaHqc/2W5eYNx1qpbg559292 rogid:Xz1objgQPrWVbwXt82fc/VOJxaI559292 rigid:mO7CjOSmIKTPpek/bK7RV0LjnHs false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)