#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43489	uniprotkb:P23510	intact:EBI-15596193|ensembl:ENSP00000368538|uniprotkb:Q13663|uniprotkb:Q2M312|uniprotkb:Q5T7M0	intact:EBI-11724451|uniprotkb:Q5JZA5|uniprotkb:Q8IV74|uniprotkb:Q9HCN9|ensembl:ENSP00000281834	psi-mi:tnr4_human(display_long)|uniprotkb:ACT35 antigen(gene name synonym)|uniprotkb:OX40L receptor(gene name synonym)|uniprotkb:TAX transcriptionally-activated glycoprotein 1 receptor(gene name synonym)|uniprotkb:TNFRSF4(gene name)|psi-mi:TNFRSF4(display_short)|uniprotkb:TXGP1L(gene name synonym)	psi-mi:tnfl4_human(display_long)|uniprotkb:TNFSF4(gene name)|psi-mi:TNFSF4(display_short)|uniprotkb:TXGP1(gene name synonym)|uniprotkb:Glycoprotein Gp34(gene name synonym)|uniprotkb:OX40 ligand(gene name synonym)|uniprotkb:TAX transcriptionally-activated glycoprotein 1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Compaan et al. (2006)	pubmed:16905106|doi:10.1016/j.str.2006.06.015|imex:IM-8451	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15596237|imex:IM-8451-3|dip:DIP-4256E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186827(gene)|ensembl:ENST00000379236(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR020445|interpro:IPR034022|rcsb pdb:1D0A|rcsb pdb:2HEV|rcsb pdb:2HEY|rcsb pdb:6OGX|rcsb pdb:6OKM|rcsb pdb:6OKN|reactome:R-HSA-5669034|refseq:NP_003318.1|refseq:XP_016857721.1|dip:DIP-3024N	go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:1900281"(positive regulation of CD4-positive, alpha-beta T cell costimulation)|go:"GO:2000572"(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042338|rcsb pdb:2HEV|reactome:R-HSA-5669034|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035712"(T-helper 2 cell activation)|go:"GO:0035713"(response to nitrogen dioxide)|refseq:NP_001284491.1|refseq:NP_003317.1|ensembl:ENSG00000117586(gene)|ensembl:ENST00000281834(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002215"(defense response to nematode)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|dip:DIP-3023N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/05	2017/08/10	rogid:JL20/CeQ7NRIa5t3EfhcOaSrxFg9606	rogid:WDG8Y8NnBoZxKOnNkwCk61G35tg9606	rigid:MUDl0o0BZdXX0Mi0zhsYjRq8Q5M	false	sufficient binding region:51-183	sufficient binding region:29-170	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23510	uniprotkb:P43488	intact:EBI-11724451|uniprotkb:Q5JZA5|uniprotkb:Q8IV74|uniprotkb:Q9HCN9|ensembl:ENSP00000281834	intact:EBI-519690|ensembl:ENSMUSP00000028024	psi-mi:tnfl4_human(display_long)|uniprotkb:TNFSF4(gene name)|psi-mi:TNFSF4(display_short)|uniprotkb:TXGP1(gene name synonym)|uniprotkb:Glycoprotein Gp34(gene name synonym)|uniprotkb:OX40 ligand(gene name synonym)|uniprotkb:TAX transcriptionally-activated glycoprotein 1(gene name synonym)	psi-mi:tnfl4_mouse(display_long)|uniprotkb:OX40 ligand(gene name synonym)|uniprotkb:Tnfsf4(gene name)|psi-mi:Tnfsf4(display_short)|uniprotkb:Ox40l(gene name synonym)|uniprotkb:Txgp1l(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Compaan et al. (2006)	pubmed:16905106|doi:10.1016/j.str.2006.06.015|imex:IM-8451	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15596276|imex:IM-8451-4|dip:DIP-57143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:1900281"(positive regulation of CD4-positive, alpha-beta T cell costimulation)|go:"GO:2000572"(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042338|rcsb pdb:2HEV|reactome:R-HSA-5669034|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035712"(T-helper 2 cell activation)|go:"GO:0035713"(response to nitrogen dioxide)|refseq:NP_001284491.1|refseq:NP_003317.1|ensembl:ENSG00000117586(gene)|ensembl:ENST00000281834(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002215"(defense response to nematode)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|dip:DIP-3023N	refseq:NP_033478.1|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035712"(T-helper 2 cell activation)|go:"GO:0035713"(response to nitrogen dioxide)|go:"GO:0035714"(cellular response to nitrogen dioxide)|go:"GO:0035783"(CD4-positive, alpha-beta T cell costimulation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:1900281"(positive regulation of CD4-positive, alpha-beta T cell costimulation)|go:"GO:2000406"(positive regulation of T cell migration)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2000570"(positive regulation of T-helper 2 cell activation)|go:"GO:2000572"(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042338|rcsb pdb:2HEW|rcsb pdb:2HEY|reactome:R-MMU-5669034|ensembl:ENSMUSG00000026700(gene)|ensembl:ENSMUST00000028024(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002215"(defense response to nematode)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002699"(positive regulation of immune effector process)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|dip:DIP-6238N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/05	2017/08/10	rogid:WDG8Y8NnBoZxKOnNkwCk61G35tg9606	rogid:+B9niauBzC76tku2QclntjQViMY10090	rigid:2ubNlrpv7HadXwcXGu4Sgath+kY	false	sufficient binding region:29-170	sufficient binding region:51-198	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23510	uniprotkb:P43488	intact:EBI-11724451|uniprotkb:Q5JZA5|uniprotkb:Q8IV74|uniprotkb:Q9HCN9|ensembl:ENSP00000281834	intact:EBI-519690|ensembl:ENSMUSP00000028024	psi-mi:tnfl4_human(display_long)|uniprotkb:TNFSF4(gene name)|psi-mi:TNFSF4(display_short)|uniprotkb:TXGP1(gene name synonym)|uniprotkb:Glycoprotein Gp34(gene name synonym)|uniprotkb:OX40 ligand(gene name synonym)|uniprotkb:TAX transcriptionally-activated glycoprotein 1(gene name synonym)	psi-mi:tnfl4_mouse(display_long)|uniprotkb:OX40 ligand(gene name synonym)|uniprotkb:Tnfsf4(gene name)|psi-mi:Tnfsf4(display_short)|uniprotkb:Ox40l(gene name synonym)|uniprotkb:Txgp1l(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Compaan et al. (2006)	pubmed:16905106|doi:10.1016/j.str.2006.06.015|imex:IM-8451	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15596297|imex:IM-8451-5|dip:DIP-57143E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:1900281"(positive regulation of CD4-positive, alpha-beta T cell costimulation)|go:"GO:2000572"(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042338|rcsb pdb:2HEV|reactome:R-HSA-5669034|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035712"(T-helper 2 cell activation)|go:"GO:0035713"(response to nitrogen dioxide)|refseq:NP_001284491.1|refseq:NP_003317.1|ensembl:ENSG00000117586(gene)|ensembl:ENST00000281834(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002215"(defense response to nematode)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|dip:DIP-3023N	refseq:NP_033478.1|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035712"(T-helper 2 cell activation)|go:"GO:0035713"(response to nitrogen dioxide)|go:"GO:0035714"(cellular response to nitrogen dioxide)|go:"GO:0035783"(CD4-positive, alpha-beta T cell costimulation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:1900281"(positive regulation of CD4-positive, alpha-beta T cell costimulation)|go:"GO:2000406"(positive regulation of T cell migration)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2000570"(positive regulation of T-helper 2 cell activation)|go:"GO:2000572"(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042338|rcsb pdb:2HEW|rcsb pdb:2HEY|reactome:R-MMU-5669034|ensembl:ENSMUSG00000026700(gene)|ensembl:ENSMUST00000028024(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002215"(defense response to nematode)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002699"(positive regulation of immune effector process)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|dip:DIP-6238N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/05	2017/08/10	rogid:WDG8Y8NnBoZxKOnNkwCk61G35tg9606	rogid:+B9niauBzC76tku2QclntjQViMY10090	rigid:2ubNlrpv7HadXwcXGu4Sgath+kY	false	sufficient binding region:29-170	sufficient binding region:51-198	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43488	uniprotkb:P43488	intact:EBI-519690|ensembl:ENSMUSP00000028024	intact:EBI-519690|ensembl:ENSMUSP00000028024	psi-mi:tnfl4_mouse(display_long)|uniprotkb:OX40 ligand(gene name synonym)|uniprotkb:Tnfsf4(gene name)|psi-mi:Tnfsf4(display_short)|uniprotkb:Ox40l(gene name synonym)|uniprotkb:Txgp1l(gene name synonym)	psi-mi:tnfl4_mouse(display_long)|uniprotkb:OX40 ligand(gene name synonym)|uniprotkb:Tnfsf4(gene name)|psi-mi:Tnfsf4(display_short)|uniprotkb:Ox40l(gene name synonym)|uniprotkb:Txgp1l(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Compaan et al. (2006)	pubmed:16905106|doi:10.1016/j.str.2006.06.015|imex:IM-8451	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15596258|imex:IM-8451-2|dip:DIP-57142E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033478.1|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035712"(T-helper 2 cell activation)|go:"GO:0035713"(response to nitrogen dioxide)|go:"GO:0035714"(cellular response to nitrogen dioxide)|go:"GO:0035783"(CD4-positive, alpha-beta T cell costimulation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:1900281"(positive regulation of CD4-positive, alpha-beta T cell costimulation)|go:"GO:2000406"(positive regulation of T cell migration)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2000570"(positive regulation of T-helper 2 cell activation)|go:"GO:2000572"(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042338|rcsb pdb:2HEW|rcsb pdb:2HEY|reactome:R-MMU-5669034|ensembl:ENSMUSG00000026700(gene)|ensembl:ENSMUST00000028024(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002215"(defense response to nematode)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002699"(positive regulation of immune effector process)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|dip:DIP-6238N	refseq:NP_033478.1|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035712"(T-helper 2 cell activation)|go:"GO:0035713"(response to nitrogen dioxide)|go:"GO:0035714"(cellular response to nitrogen dioxide)|go:"GO:0035783"(CD4-positive, alpha-beta T cell costimulation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:1900281"(positive regulation of CD4-positive, alpha-beta T cell costimulation)|go:"GO:2000406"(positive regulation of T cell migration)|go:"GO:2000525"(positive regulation of T cell costimulation)|go:"GO:2000568"(positive regulation of memory T cell activation)|go:"GO:2000570"(positive regulation of T-helper 2 cell activation)|go:"GO:2000572"(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042338|rcsb pdb:2HEW|rcsb pdb:2HEY|reactome:R-MMU-5669034|ensembl:ENSMUSG00000026700(gene)|ensembl:ENSMUST00000028024(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002215"(defense response to nematode)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002699"(positive regulation of immune effector process)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|dip:DIP-6238N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/05	2017/08/10	rogid:+B9niauBzC76tku2QclntjQViMY10090	rogid:+B9niauBzC76tku2QclntjQViMY10090	rigid:d2cZOrFF+/t0McBMmY4U1RMlkeE	false	sufficient binding region:51-198	sufficient binding region:51-198	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P43489	uniprotkb:P23510	intact:EBI-15596193|ensembl:ENSP00000368538|uniprotkb:Q13663|uniprotkb:Q2M312|uniprotkb:Q5T7M0	intact:EBI-11724451|uniprotkb:Q5JZA5|uniprotkb:Q8IV74|uniprotkb:Q9HCN9|ensembl:ENSP00000281834	psi-mi:tnr4_human(display_long)|uniprotkb:ACT35 antigen(gene name synonym)|uniprotkb:OX40L receptor(gene name synonym)|uniprotkb:TAX transcriptionally-activated glycoprotein 1 receptor(gene name synonym)|uniprotkb:TNFRSF4(gene name)|psi-mi:TNFRSF4(display_short)|uniprotkb:TXGP1L(gene name synonym)	psi-mi:tnfl4_human(display_long)|uniprotkb:TNFSF4(gene name)|psi-mi:TNFSF4(display_short)|uniprotkb:TXGP1(gene name synonym)|uniprotkb:Glycoprotein Gp34(gene name synonym)|uniprotkb:OX40 ligand(gene name synonym)|uniprotkb:TAX transcriptionally-activated glycoprotein 1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Compaan et al. (2006)	pubmed:16905106|doi:10.1016/j.str.2006.06.015|imex:IM-8451	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15596318|imex:IM-8451-1|dip:DIP-4256E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000186827(gene)|ensembl:ENST00000379236(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR020445|interpro:IPR034022|rcsb pdb:1D0A|rcsb pdb:2HEV|rcsb pdb:2HEY|rcsb pdb:6OGX|rcsb pdb:6OKM|rcsb pdb:6OKN|reactome:R-HSA-5669034|refseq:NP_003318.1|refseq:XP_016857721.1|dip:DIP-3024N	go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043382"(positive regulation of memory T cell differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045626"(negative regulation of T-helper 1 cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046641"(positive regulation of alpha-beta T cell proliferation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:1900281"(positive regulation of CD4-positive, alpha-beta T cell costimulation)|go:"GO:2000572"(positive regulation of interleukin-4-dependent isotype switching to IgE isotypes)|interpro:IPR006052(Tumor Necrosis Factor)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR021184|interpro:IPR042338|rcsb pdb:2HEV|reactome:R-HSA-5669034|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035712"(T-helper 2 cell activation)|go:"GO:0035713"(response to nitrogen dioxide)|refseq:NP_001284491.1|refseq:NP_003317.1|ensembl:ENSG00000117586(gene)|ensembl:ENST00000281834(transcript)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002215"(defense response to nematode)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002819"(regulation of adaptive immune response)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005125"(cytokine activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032700"(negative regulation of interleukin-17 production)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|dip:DIP-3023N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/05	2017/08/10	rogid:JL20/CeQ7NRIa5t3EfhcOaSrxFg9606	rogid:WDG8Y8NnBoZxKOnNkwCk61G35tg9606	rigid:MUDl0o0BZdXX0Mi0zhsYjRq8Q5M	false	sufficient binding region:51-183	sufficient binding region:29-170	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)