#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5U5U6	uniprotkb:P15374	intact:EBI-1642104	intact:EBI-954554|uniprotkb:Q5TBK8|uniprotkb:Q6IBE9|ensembl:ENSP00000366819|uniprotkb:B2R970	psi-mi:q5u5u6_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:HEL-S-50(gene name synonym)|uniprotkb:hCG_1998947(orf name)	psi-mi:uchl3_human(display_long)|uniprotkb:Ubiquitin thioesterase L3(gene name synonym)|uniprotkb:UCHL3(gene name)|psi-mi:UCHL3(display_short)	psi-mi:"MI:0415"(enzymatic study)	Renatus et al. (2006)	pubmed:16905103|doi:10.1016/j.str.2006.06.012|imex:IM-8454	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15596123|imex:IM-8454-1|dip:DIP-57144E	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|dip:DIP-29136N|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0060613"(fat pad development)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071	refseq:NP_001257881.1|refseq:NP_005993.1|ensembl:ENSG00000118939(gene)|ensembl:ENST00000377595(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043687"(post-translational protein modification)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|rcsb pdb:1UCH|rcsb pdb:1XD3|rcsb pdb:6ISU|rcsb pdb:6QML|reactome:R-HSA-5689603|reactome:R-HSA-8866652|reactome:R-HSA-8951664|dip:DIP-29135N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	rogid:cPnctBpxrgvBKBSaQmhCsyd2nRM9606	rigid:rx1WPTBIkGTPUnFYLUUVB4v1wcY	false	sufficient binding region:1-76	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O75604	uniprotkb:Q5U5U6	intact:EBI-743272|uniprotkb:Q96MB9|uniprotkb:Q9BQ21|ensembl:ENSP00000260187|uniprotkb:Q8IW04|uniprotkb:Q8IUM2|uniprotkb:B0YJB8|uniprotkb:E9PPM2	intact:EBI-1642104	psi-mi:ubp2_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 2(gene name synonym)|uniprotkb:41 kDa ubiquitin-specific protease(gene name synonym)|uniprotkb:USP2(gene name)|psi-mi:USP2(display_short)|uniprotkb:UBP41(gene name synonym)|uniprotkb:Ubiquitin thioesterase 2(gene name synonym)	psi-mi:q5u5u6_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:HEL-S-50(gene name synonym)|uniprotkb:hCG_1998947(orf name)	psi-mi:"MI:0415"(enzymatic study)	Renatus et al. (2006)	pubmed:16905103|doi:10.1016/j.str.2006.06.012|imex:IM-8454	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15596142|imex:IM-8454-2|dip:DIP-57146E	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004196.4|refseq:NP_741994.1|ensembl:ENSG00000036672(gene)|ensembl:ENST00000260187(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048512"(circadian behavior)|go:"GO:0050821"(protein stabilization)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|go:"GO:0030332"(cyclin binding)|interpro:IPR028889|interpro:IPR038765|mint:O75604|rcsb pdb:2HD5|rcsb pdb:2IBI|rcsb pdb:3NHE|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:5XU8|rcsb pdb:5XVE|rcsb pdb:6DGF|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-6804757|refseq:NP_001230688.1|refseq:XP_005271778.1|refseq:XP_005271779.1|dip:DIP-29134N	refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|dip:DIP-29136N|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0060613"(fat pad development)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/10	rogid:ILcDPhStrk+aUeVZ4y3yR4B/4y49606	rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606	rigid:JcJcXaSXcn1CMjjW+QoV4Q1EjJU	false	sufficient binding region:259-605	sufficient binding region:1-76	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P62990	uniprotkb:O75604	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	intact:EBI-743272|uniprotkb:Q96MB9|uniprotkb:Q9BQ21|ensembl:ENSP00000260187|uniprotkb:Q8IW04|uniprotkb:Q8IUM2|uniprotkb:B0YJB8|uniprotkb:E9PPM2	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:ubp2_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 2(gene name synonym)|uniprotkb:41 kDa ubiquitin-specific protease(gene name synonym)|uniprotkb:USP2(gene name)|psi-mi:USP2(display_short)|uniprotkb:UBP41(gene name synonym)|uniprotkb:Ubiquitin thioesterase 2(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Renatus et al. (2006)	pubmed:16905103|doi:10.1016/j.str.2006.06.012|imex:IM-8454	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15596163|imex:IM-8454-3|dip:DIP-57145E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	refseq:NP_004196.4|refseq:NP_741994.1|ensembl:ENSG00000036672(gene)|ensembl:ENST00000260187(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048512"(circadian behavior)|go:"GO:0050821"(protein stabilization)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|go:"GO:0030332"(cyclin binding)|interpro:IPR028889|interpro:IPR038765|mint:O75604|rcsb pdb:2HD5|rcsb pdb:2IBI|rcsb pdb:3NHE|rcsb pdb:3V6C|rcsb pdb:3V6E|rcsb pdb:5XU8|rcsb pdb:5XVE|rcsb pdb:6DGF|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-6804757|refseq:NP_001230688.1|refseq:XP_005271778.1|refseq:XP_005271779.1|dip:DIP-29134N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/05	2017/08/15	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rogid:ILcDPhStrk+aUeVZ4y3yR4B/4y49606	rigid:T3W8BBrMRcQYjHlEZvucgDdPXVc	false	-	sufficient binding region:259-605	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)