#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P68135 uniprotkb:P21454 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 intact:EBI-15595598 psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:spvb_saltm(display_long)|uniprotkb:spvB(gene name)|psi-mi:spvB(display_short)|uniprotkb:65 kDa virulence protein(gene name synonym)|uniprotkb:"NAD(+)--arginine ADP-ribosyltransferase"(gene name synonym)|uniprotkb:Toxin SpvB(gene name synonym)|uniprotkb:mkaA(gene name synonym) psi-mi:"MI:0415"(enzymatic study) Margarit et al. (2006) pubmed:16905096|doi:10.1016/j.str.2006.05.022|imex:IM-8462 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:90371(saltm)|taxid:90371(Salmonella typhimurium) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15595619|imex:IM-8462-1|dip:DIP-57152E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N go:"GO:0000166"(nucleotide binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0090729"(toxin activity)|go:"GO:0106274"(NAD+-protein-arginine ADP-ribosyltransferase activity)|go:"GO:0106275"(NADP+-protein-arginine ADP-ribosyltransferase activity)|interpro:IPR003284(Salmonella virulence plasmid 65kDa B protein)|interpro:IPR003540(Binary exotoxin A)|rcsb pdb:2GWL|rcsb pdb:2GWM|dip:DIP-29142N psi-mi:"MI:0465"(dip) - crc64:2B933EAA4C8075E3 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rogid:OnI4AM2IqMEsSeZadwtckqEGGsM90371 rigid:m7Zucj+IWqvpbkzWQQ9Oqb/7dNc false "monoadenosine diphosphoribosyl (ADP-ribosyl) modified residue":177-177 sufficient binding region:390-591 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P68135 uniprotkb:P21454 intact:EBI-367540|uniprotkb:P02568|uniprotkb:P99020 intact:EBI-15595598 psi-mi:acts_rabit(display_long)|uniprotkb:ACTA1(gene name)|psi-mi:ACTA1(display_short)|uniprotkb:ACTA(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:spvb_saltm(display_long)|uniprotkb:spvB(gene name)|psi-mi:spvB(display_short)|uniprotkb:65 kDa virulence protein(gene name synonym)|uniprotkb:"NAD(+)--arginine ADP-ribosyltransferase"(gene name synonym)|uniprotkb:Toxin SpvB(gene name synonym)|uniprotkb:mkaA(gene name synonym) psi-mi:"MI:0051"(fluorescence technology) Margarit et al. (2006) pubmed:16905096|doi:10.1016/j.str.2006.05.022|imex:IM-8462 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:90371(saltm)|taxid:90371(Salmonella typhimurium) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15595640|imex:IM-8462-2|dip:DIP-57152E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4B1Y|rcsb pdb:4B1Z|rcsb pdb:4EAH|rcsb pdb:4GY2|rcsb pdb:4H03|rcsb pdb:4H0T|rcsb pdb:4H0V|rcsb pdb:4H0X|rcsb pdb:4H0Y|rcsb pdb:4K41|rcsb pdb:4K42|rcsb pdb:4K43|rcsb pdb:4PKG|rcsb pdb:4PKH|rcsb pdb:4PKI|rcsb pdb:4PL8|rcsb pdb:4V0U|rcsb pdb:4WYB|rcsb pdb:4B1X|rcsb pdb:4Z94|rcsb pdb:5H53|rcsb pdb:5JLF|rcsb pdb:5KG8|rcsb pdb:5MVA|rcsb pdb:5MVY|rcsb pdb:5ONV|rcsb pdb:5OOC|rcsb pdb:5OOD|rcsb pdb:5OOE|rcsb pdb:5OOF|rcsb pdb:5YEE|rcsb pdb:5YPU|rcsb pdb:5ZZA|rcsb pdb:5ZZB|rcsb pdb:6AV9|rcsb pdb:6AVB|rcsb pdb:6BIH|rcsb pdb:6BNO|rcsb pdb:6BNP|rcsb pdb:6BNQ|rcsb pdb:6BNU|rcsb pdb:6BNV|rcsb pdb:5UBO|rcsb pdb:6BNW|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6FHL|rcsb pdb:6FM2|rcsb pdb:6GVC|rcsb pdb:6JBK|rcsb pdb:6JCU|rcsb pdb:6JH8|rcsb pdb:1T44|rcsb pdb:1UY5|rcsb pdb:1WUA|rcsb pdb:1Y64|rcsb pdb:1YXQ|rcsb pdb:2A3Z|rcsb pdb:2A40|rcsb pdb:2A41|rcsb pdb:2A42|rcsb pdb:2A5X|rcsb pdb:2ASM|rcsb pdb:2ASO|rcsb pdb:2ASP|rcsb pdb:2D1K|rcsb pdb:2FF3|rcsb pdb:2FF6|rcsb pdb:2FXU|rcsb pdb:2GWJ|rcsb pdb:2GWK|rcsb pdb:2HMP|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:2Q0R|rcsb pdb:2Q0U|rcsb pdb:2Q1N|go:"GO:0031432"(titin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|rcsb pdb:1ALM|rcsb pdb:1ATN|rcsb pdb:1EQY|rcsb pdb:1ESV|rcsb pdb:1H1V|rcsb pdb:1IJJ|rcsb pdb:1J6Z|rcsb pdb:1KXP|rcsb pdb:1LCU|rcsb pdb:1M8Q|rcsb pdb:1MA9|rcsb pdb:1MVW|rcsb pdb:1NWK|rcsb pdb:1O18|rcsb pdb:1O19|rcsb pdb:1O1A|rcsb pdb:1O1B|rcsb pdb:1O1C|rcsb pdb:1O1D|rcsb pdb:1O1E|rcsb pdb:1O1F|rcsb pdb:1O1G|rcsb pdb:1P8Z|rcsb pdb:1QZ5|rcsb pdb:1QZ6|rcsb pdb:1RDW|rcsb pdb:1RFQ|rcsb pdb:1RGI|rcsb pdb:1LOT|rcsb pdb:1S22|rcsb pdb:1SQK|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005884"(actin filament)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031013"(troponin I binding)|rcsb pdb:6KN8|rcsb pdb:6MGO|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6QRI|rcsb pdb:6RSW|rcsb pdb:6T1Y|rcsb pdb:6T20|rcsb pdb:6T23|rcsb pdb:6T24|rcsb pdb:6T25|rcsb pdb:6U96|rcsb pdb:6UBY|rcsb pdb:6UC0|rcsb pdb:6UC4|rcsb pdb:6VAO|rcsb pdb:6VAU|rcsb pdb:6VEC|rcsb pdb:6W17|rcsb pdb:6W7V|rcsb pdb:6WVT|rcsb pdb:6YP9|rcsb pdb:7AD9|rcsb pdb:7AHN|rcsb pdb:7AHQ|rcsb pdb:7C2F|rcsb pdb:7C2G|rcsb pdb:7C2H|rcsb pdb:7CCC|rcsb pdb:6KN7|rcsb pdb:6JH9|rcsb pdb:3J8K|rcsb pdb:2Q36|rcsb pdb:2Q97|rcsb pdb:2V51|rcsb pdb:2V52|rcsb pdb:2VCP|rcsb pdb:2VYP|rcsb pdb:2W49|rcsb pdb:2W4U|rcsb pdb:2Y83|rcsb pdb:2YJE|rcsb pdb:2YJF|rcsb pdb:2ZWH|rcsb pdb:3B5U|rcsb pdb:3BUZ|rcsb pdb:3CJB|rcsb pdb:2Q31|rcsb pdb:3CJC|rcsb pdb:3DAW|rcsb pdb:3FFK|rcsb pdb:3G37|rcsb pdb:3HBT|rcsb pdb:3J4K|rcsb pdb:3J8A|rcsb pdb:3J8I|rcsb pdb:3J8J|rcsb pdb:3JBJ|rcsb pdb:3JBK|rcsb pdb:3M1F|rcsb pdb:3M3N|rcsb pdb:3M6G|rcsb pdb:3MFP|rcsb pdb:3JBI|rcsb pdb:3MN5|rcsb pdb:3SJH|rcsb pdb:3TPQ|rcsb pdb:3TU5|rcsb pdb:3U8X|rcsb pdb:3U9Z|rcsb pdb:3UE5|rcsb pdb:4A7F|rcsb pdb:4A7H|rcsb pdb:4A7L|rcsb pdb:4A7N|rcsb pdb:4B1V|rcsb pdb:4B1W|mint:P68135|dip:DIP-29021N go:"GO:0000166"(nucleotide binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0090729"(toxin activity)|go:"GO:0106274"(NAD+-protein-arginine ADP-ribosyltransferase activity)|go:"GO:0106275"(NADP+-protein-arginine ADP-ribosyltransferase activity)|interpro:IPR003284(Salmonella virulence plasmid 65kDa B protein)|interpro:IPR003540(Binary exotoxin A)|rcsb pdb:2GWL|rcsb pdb:2GWM|dip:DIP-29142N psi-mi:"MI:0465"(dip) - crc64:2B933EAA4C8075E3 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:2vZu8ElmMe+6GjKBliCAatNGZR49986 rogid:OnI4AM2IqMEsSeZadwtckqEGGsM90371 rigid:m7Zucj+IWqvpbkzWQQ9Oqb/7dNc false - sufficient binding region:390-591 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)