#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0A855 uniprotkb:P09883 intact:EBI-7180728|ensemblbacteria:AAC73834|ensemblbacteria:BAA35406|uniprotkb:P19935|intact:MINT-7888580 intact:EBI-1029888 psi-mi:tolb_ecoli(display_long)|uniprotkb:tolB(gene name)|psi-mi:tolB(display_short)|uniprotkb:b0740(locus name)|uniprotkb:JW5100(locus name) psi-mi:cea9_ecolx(display_long)|uniprotkb:col(gene name)|psi-mi:col(display_short)|uniprotkb:cei(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Loftus et al. (2006) pubmed:16894158|doi:10.1073/pnas.0603433103|imex:IM-23798 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15595107|imex:IM-23798-1|dip:DIP-153116E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0A855|refseq:WP_001295307.1|ensemblbacteria:AAC73834(transcript)|ensemblbacteria:b0740(gene)|ensemblbacteria:BAA35406(gene)|ensemblbacteria:BAA35406(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0017038"(protein import)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032153"(cell division site)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042597"(periplasmic space)|go:"GO:0043213"(bacteriocin transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0071237"(cellular response to bacteriocin)|interpro:IPR007195(TolB, N-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR011659(WD40-like Beta Propeller)|interpro:IPR014167(Tol-Pal system beta propeller repeat, TolB)|rcsb pdb:1C5K|rcsb pdb:1CRZ|rcsb pdb:2HQS|rcsb pdb:2IVZ|rcsb pdb:2W8B|rcsb pdb:3IAX|refseq:NP_415268.1|dip:DIP-48262N refseq:YP_002533537.1|interpro:IPR016128(Pyosin/cloacin, translocation)|interpro:IPR024566|interpro:IPR024575|interpro:IPR036302|interpro:IPR037146|rcsb pdb:1BXI|rcsb pdb:1EMV|rcsb pdb:1FR2|rcsb pdb:1FSJ|rcsb pdb:1V13|rcsb pdb:1V14|rcsb pdb:1V15|rcsb pdb:2GYK|rcsb pdb:2GZE|rcsb pdb:2GZF|rcsb pdb:2GZG|rcsb pdb:2GZI|rcsb pdb:2GZJ|rcsb pdb:2IVZ|rcsb pdb:2K5X|rcsb pdb:2VLN|rcsb pdb:2VLO|rcsb pdb:2VLP|rcsb pdb:2VLQ|rcsb pdb:2WPT|rcsb pdb:3O0E|interpro:IPR003615(HNH nuclease)|rcsb pdb:4JML|rcsb pdb:5EW5|go:"GO:0004519"(endonuclease activity)|go:"GO:0005727"(extrachromosomal circular DNA)|go:"GO:0019835"(cytolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046872"(metal ion binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|refseq:WP_012644886.1|dip:DIP-16992N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:bca0IbPVHGu0zZGCXtiJpAXgZ3g83333 rogid:dNw0MxBfriwiX03AkbH/r1DorOA562 rigid:qOZ+AE+oFzNdOnfkuiaPb2dIoZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A855 uniprotkb:P09883 intact:EBI-7180728|ensemblbacteria:AAC73834|ensemblbacteria:BAA35406|uniprotkb:P19935|intact:MINT-7888580 intact:EBI-1029888 psi-mi:tolb_ecoli(display_long)|uniprotkb:tolB(gene name)|psi-mi:tolB(display_short)|uniprotkb:b0740(locus name)|uniprotkb:JW5100(locus name) psi-mi:cea9_ecolx(display_long)|uniprotkb:col(gene name)|psi-mi:col(display_short)|uniprotkb:cei(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Loftus et al. (2006) pubmed:16894158|doi:10.1073/pnas.0603433103|imex:IM-23798 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15595124|imex:IM-23798-2|dip:DIP-153116E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0A855|refseq:WP_001295307.1|ensemblbacteria:AAC73834(transcript)|ensemblbacteria:b0740(gene)|ensemblbacteria:BAA35406(gene)|ensemblbacteria:BAA35406(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0017038"(protein import)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032153"(cell division site)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042597"(periplasmic space)|go:"GO:0043213"(bacteriocin transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0071237"(cellular response to bacteriocin)|interpro:IPR007195(TolB, N-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR011659(WD40-like Beta Propeller)|interpro:IPR014167(Tol-Pal system beta propeller repeat, TolB)|rcsb pdb:1C5K|rcsb pdb:1CRZ|rcsb pdb:2HQS|rcsb pdb:2IVZ|rcsb pdb:2W8B|rcsb pdb:3IAX|refseq:NP_415268.1|dip:DIP-48262N refseq:YP_002533537.1|interpro:IPR016128(Pyosin/cloacin, translocation)|interpro:IPR024566|interpro:IPR024575|interpro:IPR036302|interpro:IPR037146|rcsb pdb:1BXI|rcsb pdb:1EMV|rcsb pdb:1FR2|rcsb pdb:1FSJ|rcsb pdb:1V13|rcsb pdb:1V14|rcsb pdb:1V15|rcsb pdb:2GYK|rcsb pdb:2GZE|rcsb pdb:2GZF|rcsb pdb:2GZG|rcsb pdb:2GZI|rcsb pdb:2GZJ|rcsb pdb:2IVZ|rcsb pdb:2K5X|rcsb pdb:2VLN|rcsb pdb:2VLO|rcsb pdb:2VLP|rcsb pdb:2VLQ|rcsb pdb:2WPT|rcsb pdb:3O0E|interpro:IPR003615(HNH nuclease)|rcsb pdb:4JML|rcsb pdb:5EW5|go:"GO:0004519"(endonuclease activity)|go:"GO:0005727"(extrachromosomal circular DNA)|go:"GO:0019835"(cytolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046872"(metal ion binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|refseq:WP_012644886.1|dip:DIP-16992N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:bca0IbPVHGu0zZGCXtiJpAXgZ3g83333 rogid:dNw0MxBfriwiX03AkbH/r1DorOA562 rigid:qOZ+AE+oFzNdOnfkuiaPb2dIoZc false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A855 uniprotkb:P09883 intact:EBI-7180728|ensemblbacteria:AAC73834|ensemblbacteria:BAA35406|uniprotkb:P19935|intact:MINT-7888580 intact:EBI-1029888 psi-mi:tolb_ecoli(display_long)|uniprotkb:tolB(gene name)|psi-mi:tolB(display_short)|uniprotkb:b0740(locus name)|uniprotkb:JW5100(locus name) psi-mi:cea9_ecolx(display_long)|uniprotkb:col(gene name)|psi-mi:col(display_short)|uniprotkb:cei(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Loftus et al. (2006) pubmed:16894158|doi:10.1073/pnas.0603433103|imex:IM-23798 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15595141|imex:IM-23798-3|dip:DIP-153116E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0A855|refseq:WP_001295307.1|ensemblbacteria:AAC73834(transcript)|ensemblbacteria:b0740(gene)|ensemblbacteria:BAA35406(gene)|ensemblbacteria:BAA35406(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0017038"(protein import)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032153"(cell division site)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042597"(periplasmic space)|go:"GO:0043213"(bacteriocin transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0071237"(cellular response to bacteriocin)|interpro:IPR007195(TolB, N-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR011659(WD40-like Beta Propeller)|interpro:IPR014167(Tol-Pal system beta propeller repeat, TolB)|rcsb pdb:1C5K|rcsb pdb:1CRZ|rcsb pdb:2HQS|rcsb pdb:2IVZ|rcsb pdb:2W8B|rcsb pdb:3IAX|refseq:NP_415268.1|dip:DIP-48262N refseq:YP_002533537.1|interpro:IPR016128(Pyosin/cloacin, translocation)|interpro:IPR024566|interpro:IPR024575|interpro:IPR036302|interpro:IPR037146|rcsb pdb:1BXI|rcsb pdb:1EMV|rcsb pdb:1FR2|rcsb pdb:1FSJ|rcsb pdb:1V13|rcsb pdb:1V14|rcsb pdb:1V15|rcsb pdb:2GYK|rcsb pdb:2GZE|rcsb pdb:2GZF|rcsb pdb:2GZG|rcsb pdb:2GZI|rcsb pdb:2GZJ|rcsb pdb:2IVZ|rcsb pdb:2K5X|rcsb pdb:2VLN|rcsb pdb:2VLO|rcsb pdb:2VLP|rcsb pdb:2VLQ|rcsb pdb:2WPT|rcsb pdb:3O0E|interpro:IPR003615(HNH nuclease)|rcsb pdb:4JML|rcsb pdb:5EW5|go:"GO:0004519"(endonuclease activity)|go:"GO:0005727"(extrachromosomal circular DNA)|go:"GO:0019835"(cytolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046872"(metal ion binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|refseq:WP_012644886.1|dip:DIP-16992N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:bca0IbPVHGu0zZGCXtiJpAXgZ3g83333 rogid:dNw0MxBfriwiX03AkbH/r1DorOA562 rigid:qOZ+AE+oFzNdOnfkuiaPb2dIoZc false - sufficient binding region:32-47 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P0A855 uniprotkb:P09883 intact:EBI-7180728|ensemblbacteria:AAC73834|ensemblbacteria:BAA35406|uniprotkb:P19935|intact:MINT-7888580 intact:EBI-1029888 psi-mi:tolb_ecoli(display_long)|uniprotkb:tolB(gene name)|psi-mi:tolB(display_short)|uniprotkb:b0740(locus name)|uniprotkb:JW5100(locus name) psi-mi:cea9_ecolx(display_long)|uniprotkb:col(gene name)|psi-mi:col(display_short)|uniprotkb:cei(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Loftus et al. (2006) pubmed:16894158|doi:10.1073/pnas.0603433103|imex:IM-23798 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:562(ecolx)|taxid:562(Escherichia coli) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15595161|imex:IM-23798-4|dip:DIP-153116E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P0A855|refseq:WP_001295307.1|ensemblbacteria:AAC73834(transcript)|ensemblbacteria:b0740(gene)|ensemblbacteria:BAA35406(gene)|ensemblbacteria:BAA35406(transcript)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0017038"(protein import)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030288"(outer membrane-bounded periplasmic space)|go:"GO:0032153"(cell division site)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042597"(periplasmic space)|go:"GO:0043213"(bacteriocin transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0071237"(cellular response to bacteriocin)|interpro:IPR007195(TolB, N-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR011659(WD40-like Beta Propeller)|interpro:IPR014167(Tol-Pal system beta propeller repeat, TolB)|rcsb pdb:1C5K|rcsb pdb:1CRZ|rcsb pdb:2HQS|rcsb pdb:2IVZ|rcsb pdb:2W8B|rcsb pdb:3IAX|refseq:NP_415268.1|dip:DIP-48262N refseq:YP_002533537.1|interpro:IPR016128(Pyosin/cloacin, translocation)|interpro:IPR024566|interpro:IPR024575|interpro:IPR036302|interpro:IPR037146|rcsb pdb:1BXI|rcsb pdb:1EMV|rcsb pdb:1FR2|rcsb pdb:1FSJ|rcsb pdb:1V13|rcsb pdb:1V14|rcsb pdb:1V15|rcsb pdb:2GYK|rcsb pdb:2GZE|rcsb pdb:2GZF|rcsb pdb:2GZG|rcsb pdb:2GZI|rcsb pdb:2GZJ|rcsb pdb:2IVZ|rcsb pdb:2K5X|rcsb pdb:2VLN|rcsb pdb:2VLO|rcsb pdb:2VLP|rcsb pdb:2VLQ|rcsb pdb:2WPT|rcsb pdb:3O0E|interpro:IPR003615(HNH nuclease)|rcsb pdb:4JML|rcsb pdb:5EW5|go:"GO:0004519"(endonuclease activity)|go:"GO:0005727"(extrachromosomal circular DNA)|go:"GO:0019835"(cytolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046872"(metal ion binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|refseq:WP_012644886.1|dip:DIP-16992N psi-mi:"MI:0465"(dip) comment:mint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:bca0IbPVHGu0zZGCXtiJpAXgZ3g83333 rogid:dNw0MxBfriwiX03AkbH/r1DorOA562 rigid:qOZ+AE+oFzNdOnfkuiaPb2dIoZc false - sufficient binding region:32-47 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)