#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P59632	uniprotkb:P59632	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Lu et al. (2006)	pubmed:16894145|doi:10.1073/pnas.0605402103|imex:IM-23797	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15595078|imex:IM-23797-1|dip:DIP-197895E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	psi-mi:"MI:0465"(dip)	-	-	figure legend:Figure 3D|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2017/08/05	2017/08/10	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rigid:Z0J5LGhuW7FF9Br9h2E9lgGF0sQ	false	yellow fluorescent protein tag:c-c|mutation decreasing interaction strength:133-133	cyan fluorescent protein tag:c-c|mutation decreasing interaction strength:133-133	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P59632	uniprotkb:P59632	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2006)	pubmed:16894145|doi:10.1073/pnas.0605402103|imex:IM-23797	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25816583|imex:IM-23797-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	psi-mi:"MI:0465"(dip)	-	-	figure legend:Figure 3 A/C|comment:After treatment with DTT, the bands of 75 kDa and 150 kDa disappeared.|antagonist:DTT|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/08/05	2020/08/21	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rigid:Z0J5LGhuW7FF9Br9h2E9lgGF0sQ	false	ha tag:c-c|mutation with no effect:81-81|mutation with no effect:117-117|mutation with no effect:121-121|mutation with no effect:127-127|mutation with no effect:130-130|mutation disrupting interaction strength:133-133|mutation with no effect:148-148|mutation with no effect:157-157	ha tag:c-c|mutation with no effect:81-81|mutation with no effect:117-117|mutation with no effect:121-121|mutation with no effect:127-127|mutation with no effect:130-130|mutation disrupting interaction strength:133-133|mutation with no effect:148-148|mutation with no effect:157-157	1	1	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P59632	uniprotkb:P59632	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	intact:EBI-15595051|uniprotkb:Q7T6R6|uniprotkb:Q7TA10|uniprotkb:Q7TA18|uniprotkb:Q7TFB0|uniprotkb:Q7TLD0|uniprotkb:Q80BV5	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:ap3a_sars(display_long)|uniprotkb:Protein 3a(gene name synonym)|uniprotkb:Accessory protein 3a(gene name synonym)|uniprotkb:Protein U274(gene name synonym)|uniprotkb:Protein X1(gene name synonym)|uniprotkb:3a(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Lu et al. (2006)	pubmed:16894145|doi:10.1073/pnas.0605402103|imex:IM-23797	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25816643|imex:IM-23797-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	reactome:R-HSA-9686347|go:"GO:0005216"(ion channel activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039511"(suppression by virus of host interferon receptor activity)|go:"GO:0039707"(pore formation by virus in membrane of host cell)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0044385"(integral to membrane of host cell)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0055036"(virion membrane)|interpro:IPR024407|dip:DIP-61251N|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683673|reactome:R-HSA-9683701|refseq:NP_828852.2	psi-mi:"MI:0465"(dip)	-	-	figure legend:Figure 3 A/C|comment:After treatment with DTT, the bands of 75 kDa and 150 kDa disappeared.|antagonist:DTT|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2017/08/05	2020/08/21	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rogid:G9PUTEgPb/GsDIis5WEafJ/h90c694009	rigid:Z0J5LGhuW7FF9Br9h2E9lgGF0sQ	false	ha tag:c-c|mutation with no effect:81-81|mutation with no effect:117-117|mutation with no effect:121-121|mutation with no effect:127-127|mutation with no effect:130-130|mutation disrupting interaction strength:133-133|mutation with no effect:148-148|mutation with no effect:157-157	ha tag:c-c|mutation with no effect:81-81|mutation with no effect:117-117|mutation with no effect:121-121|mutation with no effect:127-127|mutation with no effect:130-130|mutation disrupting interaction strength:133-133|mutation with no effect:148-148|mutation with no effect:157-157	2	2	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)