#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q80T14	uniprotkb:Q684R7	intact:EBI-15594303|ensembl:ENSMUSP00000043250|uniprotkb:E9QPG9|uniprotkb:Q80TC7|uniprotkb:Q811H8|uniprotkb:Q8BPZ4	intact:EBI-15594341|ensembl:ENSMUSP00000071627|uniprotkb:Q5H8C2|uniprotkb:Q5M7B3|uniprotkb:Q8C732	psi-mi:fras1_mouse(display_long)|uniprotkb:Fras1(gene name)|psi-mi:Fras1(display_short)|uniprotkb:Kiaa1500(gene name synonym)	psi-mi:frem1_mouse(display_long)|uniprotkb:Frem1(gene name)|psi-mi:Frem1(display_short)|uniprotkb:Protein QBRICK(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kiyozumi et al. (2006)	pubmed:16880404|doi:10.1073/pnas.0601011103|imex:IM-23788	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15594377|imex:IM-23788-1|dip:DIP-197880E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000034687(gene)|ensembl:ENSMUST00000036019(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR038081|interpro:IPR039005|interpro:IPR001007(von Willebrand factor, type C)|refseq:NP_780682.3|dip:DIP-61242N	ensembl:ENSMUSG00000059049(gene)|ensembl:ENSMUST00000071708(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007154"(cell communication)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097094"(craniofacial suture morphogenesis)|interpro:IPR001304(C-type lectin)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR032825|interpro:IPR038081|interpro:IPR039005|refseq:NP_001185740.1|refseq:NP_808531.2|refseq:XP_006538076.1|refseq:XP_006538077.1|refseq:XP_006538078.1|refseq:XP_011248357.1|dip:DIP-61243N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:2dyGfdd7aYRcFlH5KnnlPukMWz010090	rogid:/UqR+Fc6+5Fa9bKqiooQWcQH+HI10090	rigid:iTDo0TOexq9DMofmdXm5+/VSE+A	false	ha tag:n-n	flag tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q80T14	uniprotkb:Q6NVD0	intact:EBI-15594303|ensembl:ENSMUSP00000043250|uniprotkb:E9QPG9|uniprotkb:Q80TC7|uniprotkb:Q811H8|uniprotkb:Q8BPZ4	intact:EBI-15594269|ensembl:ENSMUSP00000088670|uniprotkb:Q4W2Q5|uniprotkb:Q5H8C0|uniprotkb:Q811G9|uniprotkb:Q8C4G5|uniprotkb:Q8CD46	psi-mi:fras1_mouse(display_long)|uniprotkb:Fras1(gene name)|psi-mi:Fras1(display_short)|uniprotkb:Kiaa1500(gene name synonym)	psi-mi:frem2_mouse(display_long)|uniprotkb:Frem2(gene name)|psi-mi:Frem2(display_short)|uniprotkb:Nv1(gene name synonym)|uniprotkb:ECM3 homolog(gene name synonym)|uniprotkb:NV domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kiyozumi et al. (2006)	pubmed:16880404|doi:10.1073/pnas.0601011103|imex:IM-23788	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15594377|imex:IM-23788-1|dip:DIP-197880E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000034687(gene)|ensembl:ENSMUST00000036019(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR038081|interpro:IPR039005|interpro:IPR001007(von Willebrand factor, type C)|refseq:NP_780682.3|dip:DIP-61242N	ensembl:ENSMUSG00000037016(gene)|ensembl:ENSMUST00000091137(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001822"(kidney development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0007155"(cell adhesion)|go:"GO:0007507"(heart development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048839"(inner ear development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR038081|interpro:IPR039005|refseq:NP_766450.2|dip:DIP-61241N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:2dyGfdd7aYRcFlH5KnnlPukMWz010090	rogid:AvHrXbeZv8Difc52pPXb8DKUEaM10090	rigid:iTDo0TOexq9DMofmdXm5+/VSE+A	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q80T14	uniprotkb:Q6NVD0	intact:EBI-15594303|ensembl:ENSMUSP00000043250|uniprotkb:E9QPG9|uniprotkb:Q80TC7|uniprotkb:Q811H8|uniprotkb:Q8BPZ4	intact:EBI-15594269|ensembl:ENSMUSP00000088670|uniprotkb:Q4W2Q5|uniprotkb:Q5H8C0|uniprotkb:Q811G9|uniprotkb:Q8C4G5|uniprotkb:Q8CD46	psi-mi:fras1_mouse(display_long)|uniprotkb:Fras1(gene name)|psi-mi:Fras1(display_short)|uniprotkb:Kiaa1500(gene name synonym)	psi-mi:frem2_mouse(display_long)|uniprotkb:Frem2(gene name)|psi-mi:Frem2(display_short)|uniprotkb:Nv1(gene name synonym)|uniprotkb:ECM3 homolog(gene name synonym)|uniprotkb:NV domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kiyozumi et al. (2006)	pubmed:16880404|doi:10.1073/pnas.0601011103|imex:IM-23788	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15594401|imex:IM-23788-2|dip:DIP-197882E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000034687(gene)|ensembl:ENSMUST00000036019(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0060021"(roof of mouth development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR038081|interpro:IPR039005|interpro:IPR001007(von Willebrand factor, type C)|refseq:NP_780682.3|dip:DIP-61242N	ensembl:ENSMUSG00000037016(gene)|ensembl:ENSMUST00000091137(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001822"(kidney development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0007155"(cell adhesion)|go:"GO:0007507"(heart development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048839"(inner ear development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR038081|interpro:IPR039005|refseq:NP_766450.2|dip:DIP-61241N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:2dyGfdd7aYRcFlH5KnnlPukMWz010090	rogid:AvHrXbeZv8Difc52pPXb8DKUEaM10090	rigid:M5grFXtwtzbRECF5MSsyekB6BHg	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q684R7	uniprotkb:Q6NVD0	intact:EBI-15594341|ensembl:ENSMUSP00000071627|uniprotkb:Q5H8C2|uniprotkb:Q5M7B3|uniprotkb:Q8C732	intact:EBI-15594269|ensembl:ENSMUSP00000088670|uniprotkb:Q4W2Q5|uniprotkb:Q5H8C0|uniprotkb:Q811G9|uniprotkb:Q8C4G5|uniprotkb:Q8CD46	psi-mi:frem1_mouse(display_long)|uniprotkb:Frem1(gene name)|psi-mi:Frem1(display_short)|uniprotkb:Protein QBRICK(gene name synonym)	psi-mi:frem2_mouse(display_long)|uniprotkb:Frem2(gene name)|psi-mi:Frem2(display_short)|uniprotkb:Nv1(gene name synonym)|uniprotkb:ECM3 homolog(gene name synonym)|uniprotkb:NV domain-containing protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Kiyozumi et al. (2006)	pubmed:16880404|doi:10.1073/pnas.0601011103|imex:IM-23788	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15594422|imex:IM-23788-3|dip:DIP-197881E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000059049(gene)|ensembl:ENSMUST00000071708(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0007154"(cell communication)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097094"(craniofacial suture morphogenesis)|interpro:IPR001304(C-type lectin)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR032825|interpro:IPR038081|interpro:IPR039005|refseq:NP_001185740.1|refseq:NP_808531.2|refseq:XP_006538076.1|refseq:XP_006538077.1|refseq:XP_006538078.1|refseq:XP_011248357.1|dip:DIP-61243N	ensembl:ENSMUSG00000037016(gene)|ensembl:ENSMUST00000091137(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001822"(kidney development)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0007155"(cell adhesion)|go:"GO:0007507"(heart development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048839"(inner ear development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR038081|interpro:IPR039005|refseq:NP_766450.2|dip:DIP-61241N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/05	2017/08/10	rogid:/UqR+Fc6+5Fa9bKqiooQWcQH+HI10090	rogid:AvHrXbeZv8Difc52pPXb8DKUEaM10090	rigid:J+V57sUgSweKFkkLuqpBP9nsh/Q	false	flag tag:c-c	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)