#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q06163	uniprotkb:P17214	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterhage et al. (2006)	pubmed:16862158|doi:10.1038/nsmb1125|imex:IM-8557	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15593160|imex:IM-8557-1|dip:DIP-57239E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458	psi-mi:"MI:0465"(dip)	crc64:84540735E3CD40F5	crc64:9CF552AFDA6BDEDE	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rigid:7ICUyvNvL1+v1TwuqWnpCpYVU3c	false	myc tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03096	uniprotkb:Q06163	intact:EBI-6691|uniprotkb:D6VVS0|ensemblfungi:YIL009C-A	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	psi-mi:est3_yeast(display_long)|uniprotkb:EST3(gene name)|psi-mi:EST3(display_short)|uniprotkb:YIL009C-A(locus name)|uniprotkb:Ever shorter telomeres protein 3(gene name synonym)	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:"MI:0096"(pull down)	Osterhage et al. (2006)	pubmed:16862158|doi:10.1038/nsmb1125|imex:IM-8557	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15593202|imex:IM-8557-2|dip:DIP-57240E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012256.1|sgd:S000006432|dip:DIP-6694N|ensemblfungi:YIL009C-A(gene)|ensemblfungi:YIL009C-A_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|interpro:IPR019437|rcsb pdb:2M9V	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	psi-mi:"MI:0465"(dip)	crc64:18AF3DCEEE65DB84	crc64:84540735E3CD40F5	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:qMd5GD2N9XEiLVvDpQuhyCZt/Fo559292	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	rigid:AirpJgjp4kblKVAiq6n0P+3FHoQ	false	ha tag:c-c	myc tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q03096	uniprotkb:Q06163	intact:EBI-6691|uniprotkb:D6VVS0|ensemblfungi:YIL009C-A	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	psi-mi:est3_yeast(display_long)|uniprotkb:EST3(gene name)|psi-mi:EST3(display_short)|uniprotkb:YIL009C-A(locus name)|uniprotkb:Ever shorter telomeres protein 3(gene name synonym)	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:"MI:0096"(pull down)	Osterhage et al. (2006)	pubmed:16862158|doi:10.1038/nsmb1125|imex:IM-8557	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15593181|imex:IM-8557-4|dip:DIP-57240E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012256.1|sgd:S000006432|dip:DIP-6694N|ensemblfungi:YIL009C-A(gene)|ensemblfungi:YIL009C-A_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|interpro:IPR019437|rcsb pdb:2M9V	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	psi-mi:"MI:0465"(dip)	crc64:18AF3DCEEE65DB84	crc64:84540735E3CD40F5	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:qMd5GD2N9XEiLVvDpQuhyCZt/Fo559292	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	rigid:AirpJgjp4kblKVAiq6n0P+3FHoQ	false	ha tag:c-c	myc tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06163	uniprotkb:Q03096	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	intact:EBI-6691|uniprotkb:D6VVS0|ensemblfungi:YIL009C-A	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:est3_yeast(display_long)|uniprotkb:EST3(gene name)|psi-mi:EST3(display_short)|uniprotkb:YIL009C-A(locus name)|uniprotkb:Ever shorter telomeres protein 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterhage et al. (2006)	pubmed:16862158|doi:10.1038/nsmb1125|imex:IM-8557	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15593223|imex:IM-8557-3|dip:DIP-57241E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	refseq:NP_012256.1|sgd:S000006432|dip:DIP-6694N|ensemblfungi:YIL009C-A(gene)|ensemblfungi:YIL009C-A_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003924"(GTPase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0051973"(positive regulation of telomerase activity)|interpro:IPR019437|rcsb pdb:2M9V	psi-mi:"MI:0465"(dip)	crc64:84540735E3CD40F5	crc64:18AF3DCEEE65DB84	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	rogid:qMd5GD2N9XEiLVvDpQuhyCZt/Fo559292	rigid:+zs2WJQEVK+upEjTJj2UGiZevaw	false	myc tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06163	uniprotkb:P17214	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Osterhage et al. (2006)	pubmed:16862158|doi:10.1038/nsmb1125|imex:IM-8557	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15593223|imex:IM-8557-3|dip:DIP-57241E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458	psi-mi:"MI:0465"(dip)	crc64:84540735E3CD40F5	crc64:9CF552AFDA6BDEDE	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/05	2017/08/10	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rigid:+zs2WJQEVK+upEjTJj2UGiZevaw	false	myc tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)