#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P57729 uniprotkb:Q08484 intact:EBI-6552718|ensembl:ENSP00000243662|uniprotkb:Q53XK7 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab38_human(display_long)|uniprotkb:RAB38(gene name)|psi-mi:RAB38(display_short)|uniprotkb:Melanoma antigen NY-MEL-1(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592449|imex:IM-21834-4|dip:DIP-192253E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000123892(gene)|ensembl:ENST00000243662(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012505"(endomembrane system)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0032438"(melanosome organization)|go:"GO:0033162"(melanosome membrane)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0035650"(AP-1 adaptor complex binding)|go:"GO:0035651"(AP-3 adaptor complex binding)|go:"GO:0036461"(BLOC-2 complex binding)|go:"GO:0042470"(melanosome)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0060155"(platelet dense granule organization)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0090383"(phagosome acidification)|go:"GO:1903232"(melanosome assembly)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030697|rcsb pdb:6HDU|rcsb pdb:6S5H|reactome:R-HSA-8873719|reactome:R-HSA-8876198|go:"GO:0005802"(trans-Golgi network)|refseq:NP_071732.1|dip:DIP-60520N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:wE7byI3eUYwjSh5A01J4lL+4dFM9606 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:ouQYDHNb2NuD1ZSeDHRFuvQXLsE false sufficient binding region:2-211 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35278 uniprotkb:Q08484 intact:EBI-2551532|ensembl:ENSMUSP00000102987|uniprotkb:Q8R2N8|uniprotkb:Q8R1V8 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab5c_mouse(display_long)|uniprotkb:Rab5c(gene name)|psi-mi:Rab5c(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592428|imex:IM-21834-3|dip:DIP-192240E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000019173(gene)|ensembl:ENSMUST00000107364(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042470"(melanosome)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1HUQ|rcsb pdb:1Z07|rcsb pdb:1Z0D|reactome:R-MMU-432722|reactome:R-MMU-6798695|reactome:R-MMU-8856828|reactome:R-MMU-8873719|reactome:R-MMU-8876198|go:"GO:0019003"(GDP binding)|refseq:NP_077776.2|dip:DIP-56521N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:+RBgzzjAJ3ddDtcAq0IDIzHekYE10090 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:jxesL6F+mvR9/Xc6C7yAjYrk7sg false sufficient binding region:2-216 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08484 uniprotkb:O35963 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C intact:EBI-6379521|ensembl:ENSMUSP00000063054|uniprotkb:Q3TWI8 psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:rb33b_mouse(display_long)|uniprotkb:Rab33b(gene name)|psi-mi:Rab33b(display_short) psi-mi:"MI:0114"(x-ray crystallography) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592407|imex:IM-21834-2|dip:DIP-192233E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 ensembl:ENSMUSG00000027739(gene)|ensembl:ENSMUST00000054387(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0098793"(presynapse)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903434"(negative regulation of constitutive secretory pathway)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041822|mint:O35963|rcsb pdb:1Z06|rcsb pdb:2G77|rcsb pdb:6SUR|reactome:R-MMU-6811438|reactome:R-MMU-8854214|reactome:R-MMU-8873719|dip:DIP-60512N|refseq:NP_058554.1 psi-mi:"MI:0465"(dip) crc64:08C1A26B6ED37E13 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rogid:x4MceDjJ1Z+aDXtSU2c7iIc6iuQ10090 rigid:IvlKHNwxT/qchavVF/6796fll7I false sufficient binding region:244-637 sufficient binding region:15-202 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P61106 uniprotkb:Q08484 intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592385|imex:IM-21834-1|dip:DIP-192244E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057406.2|ensembl:ENSG00000119396(gene)|ensembl:ENST00000373840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:ufUNLqgq4PFFYP7SZ8Da3vJS1Oo false sufficient binding region:2-215 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08484 uniprotkb:O35963 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C intact:EBI-6379521|ensembl:ENSMUSP00000063054|uniprotkb:Q3TWI8 psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:rb33b_mouse(display_long)|uniprotkb:Rab33b(gene name)|psi-mi:Rab33b(display_short) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592574|imex:IM-21834-8|dip:DIP-192233E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 ensembl:ENSMUSG00000027739(gene)|ensembl:ENSMUST00000054387(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0098793"(presynapse)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903434"(negative regulation of constitutive secretory pathway)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041822|mint:O35963|rcsb pdb:1Z06|rcsb pdb:2G77|rcsb pdb:6SUR|reactome:R-MMU-6811438|reactome:R-MMU-8854214|reactome:R-MMU-8873719|dip:DIP-60512N|refseq:NP_058554.1 psi-mi:"MI:0465"(dip) crc64:08C1A26B6ED37E13 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rogid:x4MceDjJ1Z+aDXtSU2c7iIc6iuQ10090 rigid:IvlKHNwxT/qchavVF/6796fll7I false sufficient binding region:244-637 sufficient binding region:15-202 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8K386 uniprotkb:Q08484 intact:EBI-911594 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab15_mouse(display_long)|uniprotkb:Rab15(gene name)|psi-mi:Rab15(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592553|imex:IM-21834-7|dip:DIP-192245E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-37728N|reactome:R-MMU-8873719|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0055037"(recycling endosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041826 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:wHLDIWOGQ1DzmpUM7f3kMmNXtYQ10090 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:+lKcIuHwV3Xi+fpToXolbGRGnlg false sufficient binding region:2-212 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35288 uniprotkb:Q08484 intact:EBI-15592491 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab23_mouse(display_long)|uniprotkb:Rab23(gene name)|psi-mi:Rab23(display_short)|uniprotkb:Opb(gene name synonym)|uniprotkb:Protein open brain(gene name synonym)|uniprotkb:Rab-15(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592532|imex:IM-21834-6|dip:DIP-192249E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000045"(autophagosome assembly)|go:"GO:0001843"(neural tube closure)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0021513"(spinal cord dorsal/ventral patterning)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030054"(cell junction)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0060271"(cilium assembly)|go:"GO:0097094"(craniofacial suture morphogenesis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR034114|rcsb pdb:1Z22|rcsb pdb:1Z2A|reactome:R-MMU-8873719|dip:DIP-60517N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:wtxZ7S3Wdtf58Q1QNwYtQ4VKa0410090 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:5Ezrp/A/EkhTaxLlQVa+eTbr7YA false sufficient binding region:2-237 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51150 uniprotkb:Q08484 intact:EBI-8321380|intact:MINT-1864693|ensembl:ENSMUSP00000092658|ensembl:ENSMUSP00000109226|ensembl:ENSMUSP00000109227|ensembl:ENSMUSP00000109228|ensembl:ENSMUSP00000109230 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab7a_mouse(display_long)|uniprotkb:Rab7a(gene name)|psi-mi:Rab7a(display_short)|uniprotkb:Rab7(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592595|imex:IM-21834-9|dip:DIP-192241E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001280581.1|refseq:NP_001280582.1|refseq:NP_001280583.1|refseq:NP_001280584.1|refseq:NP_033031.2|dip:DIP-60513N|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9013148|ensembl:ENSMUSG00000079477(gene)|ensembl:ENSMUST00000095048(transcript)|ensembl:ENSMUST00000113596(transcript)|ensembl:ENSMUST00000113597(transcript)|ensembl:ENSMUST00000113598(transcript)|ensembl:ENSMUST00000113600(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045453"(bone resorption)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0061724"(lipophagy)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51150|rcsb pdb:5Z2M|reactome:R-MMU-2132295|reactome:R-MMU-6798695|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) comment:mint|function:"Involved in late endocytic transport. Contributes to the maturation of phagosomes (acidification)" crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:AJbKizzw4zCAn+roRF2Im1Tt4xE10090 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:6wqjJktDPcjV8xTfATM9hoJ33ZE false sufficient binding region:5-176 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P07560 uniprotkb:Q08484 intact:EBI-16858|uniprotkb:D6VTM4|ensemblfungi:YFL005W intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:sec4_yeast(display_long)|uniprotkb:SEC4(gene name)|psi-mi:SEC4(display_short)|uniprotkb:SRO6(gene name synonym)|uniprotkb:Suppressor of RHO3 protein 6(gene name synonym)|uniprotkb:YFL005W(locus name) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592470|imex:IM-21834-5|dip:DIP-192236E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YFL005W(gene)|ensemblfungi:YFL005W_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0006914"(autophagy)|go:"GO:0007107"(membrane addition at site of cytokinesis)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030133"(transport vesicle)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0031321"(ascospore-type prospore assembly)|go:"GO:0031982"(vesicle)|go:"GO:0043332"(mating projection tip)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1G17|rcsb pdb:2EQB|rcsb pdb:2OCY|rcsb pdb:3CPH|rcsb pdb:4Z8Y|rcsb pdb:4ZDW|reactome:R-SCE-6798695|reactome:R-SCE-8873719|reactome:R-SCE-8876198|rcsb pdb:1G16|refseq:NP_116650.1|sgd:S000001889|dip:DIP-2492N|mint:P07560 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) crc64:7DEDF7DCC7533BA7 crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:jJuZIOzwwlmNRExLIJtbs9vd/so559292 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:fz9KGJm2qZ4H8p6SdiqfRQwk5CM false sufficient binding region:17-184 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6PHN9 uniprotkb:Q08484 intact:EBI-1373353|ensembl:ENSMUSP00000031492 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab35_mouse(display_long)|uniprotkb:Rab35(gene name)|psi-mi:Rab35(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592616|imex:IM-21834-10|dip:DIP-192252E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_937806.1|dip:DIP-38238N|ensembl:ENSMUSG00000029518(gene)|ensembl:ENSMUST00000031492(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042470"(melanosome)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|mint:Q6PHN9|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo10090 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:EGKf2nEDxWdvA5jsOJj1YzorPGw false sufficient binding region:2-201 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H0U4 uniprotkb:Q08484 intact:EBI-1045214|ensembl:ENSP00000310226|uniprotkb:A8K7S1 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab1b_human(display_long)|uniprotkb:RAB1B(gene name)|psi-mi:RAB1B(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592637|imex:IM-21834-11|dip:DIP-192237E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000174903(gene)|ensembl:ENST00000311481(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0019068"(virion assembly)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_112243.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q9H0U4|rcsb pdb:3JZA|rcsb pdb:3NKV|rcsb pdb:4HLQ|rcsb pdb:4I1O|rcsb pdb:5O74|rcsb pdb:5SZH|rcsb pdb:5SZK|rcsb pdb:6SKU|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42462N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:EI6DHq7xCboSkoqGY5NmVY4Iqf09606 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:utidrqD/O5a8bttMCbXQ02X0Ufs false sufficient binding region:?-? sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35285 uniprotkb:Q08484 intact:EBI-6552605|ensembl:ENSMUSP00000029024|uniprotkb:Q3UCA7|uniprotkb:Q91VD4 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rb22a_mouse(display_long)|uniprotkb:Rab22a(gene name)|psi-mi:Rab22a(display_short)|uniprotkb:Rab22(gene name synonym)|uniprotkb:Rab-14(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592660|imex:IM-21834-12|dip:DIP-192248E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000027519(gene)|ensembl:ENSMUST00000029024(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0097494"(regulation of vesicle size)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P35285|rcsb pdb:1YVD|rcsb pdb:1Z0J|reactome:R-MMU-8873719|refseq:NP_077756.2|dip:DIP-60516N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Msg30/nyg0ZQXr/FJYlnTy6isCM10090 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:OFF3JjUQEdMfO5nOkmhz4ofMBpQ false biological feature:2-194 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08484 uniprotkb:O35963 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C intact:EBI-6379521|ensembl:ENSMUSP00000063054|uniprotkb:Q3TWI8 psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:rb33b_mouse(display_long)|uniprotkb:Rab33b(gene name)|psi-mi:Rab33b(display_short) psi-mi:"MI:0071"(molecular sieving) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592681|imex:IM-21834-13|dip:DIP-192233E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 ensembl:ENSMUSG00000027739(gene)|ensembl:ENSMUST00000054387(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0098793"(presynapse)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903434"(negative regulation of constitutive secretory pathway)|go:"GO:2000156"(regulation of retrograde vesicle-mediated transport, Golgi to ER)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041822|mint:O35963|rcsb pdb:1Z06|rcsb pdb:2G77|rcsb pdb:6SUR|reactome:R-MMU-6811438|reactome:R-MMU-8854214|reactome:R-MMU-8873719|dip:DIP-60512N|refseq:NP_058554.1 psi-mi:"MI:0465"(dip) crc64:08C1A26B6ED37E13 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rogid:x4MceDjJ1Z+aDXtSU2c7iIc6iuQ10090 rigid:IvlKHNwxT/qchavVF/6796fll7I false sufficient binding region:244-637 sufficient binding region:15-202 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9NP72-1 uniprotkb:Q08484 intact:EBI-15592702|ensembl:ENSP00000349415|ensembl:ENSP00000507542 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:q9np72-1(display_long)|uniprotkb:RAB18(gene name)|psi-mi:RAB18(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592707|imex:IM-21834-14|dip:DIP-192246E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-722247(isoform-parent)|ensembl:ENSG00000099246(gene)|ensembl:ENST00000356940(transcript)|ensembl:ENST00000682082(transcript) refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:xw6DaP3FsJo34UZC/jqjJEWfSeg9606 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:jrS5/2Y05WSiBTcpYEsUmTqTPnU false sufficient binding region:2-206 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35284 uniprotkb:Q08484 intact:EBI-917322 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab12_rat(display_long)|uniprotkb:Rab12(gene name)|psi-mi:Rab12(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592728|imex:IM-21834-15|dip:DIP-192242E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:3527|refseq:NP_037149.1|dip:DIP-36918N|reactome:R-RNO-8873719|reactome:R-RNO-8876198|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009306"(protein secretion)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0030141"(secretory granule)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041830 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:NngYHnA7ms8iRkLJCPqXTONuEFU10116 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:XEscpvrdfk7uA1UJm8FKptCP2Vw false sufficient binding region:3-190 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P63011 uniprotkb:Q08484 intact:EBI-398393|uniprotkb:P05713|uniprotkb:Q3TSL4|ensembl:ENSMUSP00000034301|ensembl:ENSMUSP00000105719|ensembl:ENSMUSP00000105720|ensembl:ENSMUSP00000105717 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab3a_mouse(display_long)|uniprotkb:Rab3a(gene name)|psi-mi:Rab3a(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592749|imex:IM-21834-16|dip:DIP-192238E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001159871.1|refseq:NP_033027.1|ensembl:ENSMUSG00000031840(gene)|refseq:XP_006509666.1|refseq:NP_001314976.1|dip:DIP-31051N|ensembl:ENSMUST00000034301(transcript)|ensembl:ENSMUST00000110090(transcript)|ensembl:ENSMUST00000110092(transcript)|ensembl:ENSMUST00000110093(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0003016"(respiratory system process)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009306"(protein secretion)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030141"(secretory granule)|go:"GO:0030324"(lung development)|go:"GO:0030424"(axon)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060203"(clathrin-sculpted glutamate transport vesicle membrane)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061670"(evoked neurotransmitter secretion)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1905684"(regulation of plasma membrane repair)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|mint:P63011|reactome:R-MMU-181429|reactome:R-MMU-181430|reactome:R-MMU-210500|reactome:R-MMU-212676|reactome:R-MMU-264642|reactome:R-MMU-6798695|reactome:R-MMU-8873719|reactome:R-MMU-8876198|reactome:R-MMU-888590 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Skrsn0x0LP/jAuOk1LQ4ataeiDA10090 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:TzybrITL32ulV2W8ZPWcxMmxK+c false sufficient binding region:18-186 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q15771 uniprotkb:Q08484 intact:EBI-3924277|uniprotkb:Q96CI8|uniprotkb:Q6FGK1|ensembl:ENSP00000260056|ensembl:ENSP00000435089|ensembl:ENSP00000435189|ensembl:ENSP00000478702|uniprotkb:Q6MZH2 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab30_human(display_long)|uniprotkb:RAB30(gene name)|psi-mi:RAB30(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592770|imex:IM-21834-17|dip:DIP-192251E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001272988.1|refseq:NP_001272989.1|refseq:NP_001272990.1|refseq:NP_055303.2|ensembl:ENSG00000137502(gene)|ensembl:ENST00000260056(transcript)|ensembl:ENST00000527633(transcript)|ensembl:ENST00000533486(transcript)|ensembl:ENST00000612684(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007030"(Golgi organization)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041820|rcsb pdb:2EW1|reactome:R-HSA-6811438|reactome:R-HSA-8873719|dip:DIP-60519N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:Qh3KHalGgosuTb+p7Oe39ix9/UM9606 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:fawsf/9Tl7vprH1QIA8O8J4Udp0 false sufficient binding region:2-203 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32939 uniprotkb:P48365 intact:EBI-29509|uniprotkb:D6VZH4|ensemblfungi:YML001W intact:EBI-8018|uniprotkb:D6VRC2|ensemblfungi:YDL234C psi-mi:ypt7_yeast(display_long)|uniprotkb:YPT7(gene name)|psi-mi:YPT7(display_short)|uniprotkb:VAM4(gene name synonym)|uniprotkb:Vacuolar morphology protein 4(gene name synonym)|uniprotkb:YM8270.02(orf name)|uniprotkb:YML001W(locus name) psi-mi:gyp7_yeast(display_long)|uniprotkb:YDL234C(locus name)|uniprotkb:GYP7(gene name)|psi-mi:GYP7(display_short)|uniprotkb:GAP for YPT7(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592791|imex:IM-21834-18|dip:DIP-192234E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013713.1|sgd:S000004460|dip:DIP-1735N|mint:P32939|ensemblfungi:YML001W(gene)|ensemblfungi:YML001W_mRNA(transcript)|go:"GO:0000011"(vacuole inheritance)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1990816"(vacuole-mitochondrion membrane contact site)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1KY2|rcsb pdb:1KY3|rcsb pdb:4PHF|rcsb pdb:4PHG|rcsb pdb:4PHH|reactome:R-SCE-6798695|reactome:R-SCE-8854214|reactome:R-SCE-8873719|reactome:R-SCE-8876198|reactome:R-SCE-9013405|reactome:R-SCE-9013406 refseq:NP_010047.1|sgd:S000002393|mint:P48365|dip:DIP-6769N|ensemblfungi:YDL234C(gene)|ensemblfungi:YDL234C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|reactome:R-SCE-8854214 psi-mi:"MI:0465"(dip) crc64:0E2B72BDA7F7CEE5 crc64:10F0F2B11A9993A6 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:ZR2uZTxqTXnSamelDJbMoEI2af8559292 rogid:5XlZW9P+NJttkKpJcnVQe7lSj94559292 rigid:dGlTiBw6YAFpRt1dJc/ofinj4bU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P35294 uniprotkb:Q08484 intact:EBI-6552478|ensembl:ENSMUSP00000031986|uniprotkb:O35697|uniprotkb:Q6GTV2 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab19_mouse(display_long)|uniprotkb:Rab19(gene name)|psi-mi:Rab19(display_short) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592808|imex:IM-21834-19|dip:DIP-192247E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000031986(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0012505"(endomembrane system)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|reactome:R-MMU-8873719|ensembl:ENSMUSG00000029923(gene)|refseq:NP_035356.1|dip:DIP-60515N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:laVcaDu7ZxcIYlutmPw3I5rUpqk10090 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:E4EhqyrchnY8ZP1az2StxB3dKnM false sufficient binding region:2-217 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P51153 uniprotkb:Q08484 intact:EBI-1780121|uniprotkb:Q5U0A6|uniprotkb:Q6GPG6|uniprotkb:Q96GU4|uniprotkb:A8K6B5|uniprotkb:D3DV67|ensembl:ENSP00000357564 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab13_human(display_long)|uniprotkb:RAB13(gene name)|psi-mi:RAB13(display_short)|uniprotkb:GIG4(orf name)|uniprotkb:Cell growth-inhibiting gene 4 protein(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592829|imex:IM-21834-20|dip:DIP-192243E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002861.1|refseq:NP_001258967.1|dip:DIP-40268N|ensembl:ENSG00000143545(gene)|ensembl:ENST00000368575(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035767"(endothelial cell chemotaxis)|go:"GO:0043005"(neuron projection)|go:"GO:0044795"(trans-Golgi network to recycling endosome transport)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P51153|reactome:R-HSA-1445148|reactome:R-HSA-8873719|reactome:R-HSA-8876198 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:XopTW/3AqUPyTi66Nf0HYlkD6Fw9606 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:IPPaznrWeqAMolETaF8uLsT4lvA false sufficient binding region:2-203 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P20338 uniprotkb:Q08484 intact:EBI-722284|uniprotkb:Q9BQ44|uniprotkb:Q5T7P7|ensembl:ENSP00000355651 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab4a_human(display_long)|uniprotkb:RAB4A(gene name)|psi-mi:RAB4A(display_short)|uniprotkb:RAB4(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592850|imex:IM-21834-21|dip:DIP-192239E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004569.2|refseq:NP_001258927.1|dip:DIP-372N|ensembl:ENSG00000168118(gene)|ensembl:ENST00000366690(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041819|mint:P20338|rcsb pdb:1YU9|rcsb pdb:1Z0K|rcsb pdb:2BMD|rcsb pdb:2BME|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8875656 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:D2WXh1fcXRVjoim9QiqLpNdq2Gk9606 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:exFJm/kURQgIGjr9PlCtj7fFEm8 false sufficient binding region:2-213 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q14964 uniprotkb:Q08484 intact:EBI-3048577|ensembl:ENSP00000322594|uniprotkb:A8KAA4|uniprotkb:Q8N6W2 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rb39a_human(display_long)|uniprotkb:RAB39A(gene name)|psi-mi:RAB39A(display_short)|uniprotkb:RAB39(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592871|imex:IM-21834-22|dip:DIP-192254E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000179331(gene)|ensembl:ENST00000320578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041818|reactome:R-HSA-6811438|reactome:R-HSA-8873719|reactome:R-HSA-8876198|refseq:NP_059986.1|dip:DIP-60521N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:jpkNU7VaaBLmc8P2kLuNq++1T2I9606 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:bQmACRirl2b9zECFMsSviFhiAhw false sufficient binding region:2-215 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P01123 uniprotkb:Q08484 intact:EBI-29496|uniprotkb:D6VTJ2|ensemblfungi:YFL038C intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:ypt1_yeast(display_long)|uniprotkb:YFL038C(locus name)|uniprotkb:YPT1(gene name)|psi-mi:YPT1(display_short)|uniprotkb:YP2(gene name synonym)|uniprotkb:Rab GTPase YPT1(gene name synonym)|uniprotkb:Transport GTPase YPT1(gene name synonym)|uniprotkb:Protein YP2(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592892|imex:IM-21834-23|dip:DIP-192235E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116615.1|sgd:S000001856|dip:DIP-2019N|mint:P01123|ensemblfungi:YFL038C(gene)|ensemblfungi:YFL038C_mRNA(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0016236"(macroautophagy)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032258"(cytoplasm to vacuole transport by the Cvt pathway)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0061709"(reticulophagy)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1900101"(regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1990261"(pre-mRNA catabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1UKV|rcsb pdb:1YZN|rcsb pdb:2BCG|rcsb pdb:3CUE|rcsb pdb:7KMT|reactome:R-SCE-162658|reactome:R-SCE-204005|reactome:R-SCE-6807878|reactome:R-SCE-6811434|reactome:R-SCE-8873719|reactome:R-SCE-8876198 refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) crc64:F8C704F6BF2D227B crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:IMz/iERXs1zvX+wgJ9x7Uk0ovQ8559292 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:XdP8sh7DJXEDqI2ECSFRUNigo5w false sufficient binding region:4-178 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q63481 uniprotkb:Q08484 intact:EBI-6513837|ensembl:ENSRNOP00000067600 intact:EBI-8005|uniprotkb:O00028|uniprotkb:D6W2D3|ensemblfungi:YOR070C psi-mi:rab7l_rat(display_long)|uniprotkb:Rab29(gene name)|psi-mi:Rab29(display_short)|uniprotkb:Rab-7-like protein 1(gene name synonym)|uniprotkb:Rab7l1(gene name synonym)|uniprotkb:Ras-related protein Rab-29(gene name synonym) psi-mi:gyp1_yeast(display_long)|uniprotkb:GYP1(gene name)|psi-mi:GYP1(display_short)|uniprotkb:YOR070C(locus name)|uniprotkb:YOR29-21(orf name)|uniprotkb:GAP for YPT1(gene name synonym) psi-mi:"MI:0419"(gtpase assay) Pan et al. (2006) pubmed:16855591|doi:10.1038/nature04847|imex:IM-21834 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15592913|imex:IM-21834-24|dip:DIP-192250E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSRNOG00000049641(gene)|ensembl:ENSRNOT00000073669(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0009617"(response to bacterium)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0019003"(GDP binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042110"(T cell activation)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0055037"(recycling endosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901998"(toxin transport)|go:"GO:1903441"(protein localization to ciliary membrane)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030697|reactome:R-RNO-8873719|refseq:XP_006249806.1|refseq:XP_006249807.1|refseq:NP_598274.1|rgd:620892|dip:DIP-60518N refseq:NP_014713.1|sgd:S000005596|dip:DIP-1258N|ensemblfungi:YOR070C(gene)|ensemblfungi:YOR070C_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:1FKM|rcsb pdb:2G77 psi-mi:"MI:0465"(dip) - crc64:08C1A26B6ED37E13 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:QqDFGemZdlQZPQOpwxLlS/5Yi0U10116 rogid:mWMH3YXs+4K+v0q+T+tCI95HIx4559292 rigid:AxR8y0qChJehN8SlbmhQJLzcCEY false sufficient binding region:2-203 sufficient binding region:244-637 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)