#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96E22 uniprotkb:Q9NQC3-2 intact:EBI-6949352|ensembl:ENSP00000357480|uniprotkb:O00251|intact:MINT-3052208|uniprotkb:B2RWQ4 intact:EBI-10296096|ensembl:ENSP00000322147 psi-mi:ngbr_human(display_long)|uniprotkb:NUS1(gene name)|psi-mi:NUS1(display_short)|uniprotkb:C6orf68(gene name synonym)|uniprotkb:NGBR(gene name synonym)|uniprotkb:Nuclear undecaprenyl pyrophosphate synthase 1 homolog(gene name synonym)|uniprotkb:Nogo-B receptor(gene name synonym)|uniprotkb:Cis-prenyltransferase subunit NgBR(gene name synonym) psi-mi:q9nqc3-2(display_long)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:Foocen(gene name synonym)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name)|uniprotkb:ASY(isoform synonym)|uniprotkb:Foocen-M(isoform synonym)|uniprotkb:Nogo-B(isoform synonym)|uniprotkb:RTN-xS(isoform synonym)|uniprotkb:Nogo-B1(isoform synonym)|uniprotkb:RTN4B(isoform synonym)|uniprotkb:RTN4B1(isoform synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Miao et al. (2006) pubmed:16835300|doi:10.1073/pnas.0602427103|imex:IM-23766 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15591080|imex:IM-23766-1|dip:DIP-197852E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000153989(gene)|ensembl:ENST00000368494(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006489"(dolichyl diphosphate biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019408"(dolichol biosynthetic process)|rcsb pdb:6W2L|rcsb pdb:6Z1N|reactome:R-HSA-446199|reactome:R-HSA-4755609|go:"GO:0030154"(cell differentiation)|go:"GO:0032383"(regulation of intracellular cholesterol transport)|go:"GO:0035268"(protein mannosylation)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045547"(dehydrodolichyl diphosphate synthase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:1904423"(dehydrodolichyl diphosphate synthase complex)|interpro:IPR001441(Di-trans-poly-cis-decaprenylcistransferase)|interpro:IPR036424|interpro:IPR038887|refseq:NP_612468.1|dip:DIP-61225N intact:EBI-715945(isoform-parent)|ensembl:ENSG00000115310(gene)|ensembl:ENST00000317610(transcript)|uniprotkb:Q9NQC3-2(isoform-parent) psi-mi:"MI:0465"(dip) comment:mint|function:Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. Able to regulate vascular remodeling and angiogenesis. Its similarity with UPP synthetase proteins suggests that it may act as a scaffold for the binding of isoprenyl lipids and/or prenylated proteins|comment:homomint - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:htBbXzyI2bJDFvyuFFWIeAnF3sc9606 rogid:2r64W1jh2yaSciLBRcCthaCHWWA9606 rigid:ql3ock8jy3ej7hIPoRRDJurofZ0 false ha tag:c-c myc tag:?-?|sufficient binding region:1-200 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)