#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P21651	uniprotkb:P21651	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Henderson et al. (2006)	imex:IM-26323|pubmed:16814718	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715736|imex:IM-26323-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:46F426AC0DFDFAD0	crc64:46F426AC0DFDFAD0	figure legend:Figure 5 B/D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:g9F096gZXhiXDsPNkGW3UmU9xEU	false	mutation decreasing interaction strength:30-30|mutation with no effect:271-271|mutation decreasing interaction strength:30-30,271-271	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P29467	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-2566907|uniprotkb:P87265|uniprotkb:D3DLU5|ensemblfungi:YER044C-A	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:mei4_yeast(display_long)|uniprotkb:MEI4(gene name)|psi-mi:MEI4(display_short)|uniprotkb:YER044BC(orf name)|uniprotkb:YER044C-A(locus name)	psi-mi:"MI:0018"(two hybrid)	Henderson et al. (2006)	imex:IM-26323|pubmed:16814718	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715747|imex:IM-26323-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	sgd:S000001954|refseq:NP_010963.1|ensemblfungi:YER044C-A(gene)|ensemblfungi:YER044C-A_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0006310"(DNA recombination)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR025888	-	crc64:46F426AC0DFDFAD0	-	figure legend:Figure 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:A9neKqDQ4o5xP4QUOSRJQvJetnY559292	rigid:Ii2VK1iJH9buRC7a83Fg8a47yv0	false	mutation decreasing interaction strength:30-30|mutation with no effect:271-271|mutation decreasing interaction strength:30-30,271-271	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P21651	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Henderson et al. (2006)	imex:IM-26323|pubmed:16814718	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715758|imex:IM-26323-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:46F426AC0DFDFAD0	crc64:46F426AC0DFDFAD0	figure legend:Figure 5Di|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:g9F096gZXhiXDsPNkGW3UmU9xEU	false	mutation disrupting interaction strength:30-30	mutation disrupting interaction strength:30-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P21651	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Henderson et al. (2006)	imex:IM-26323|pubmed:16814718	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715776|imex:IM-26323-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:46F426AC0DFDFAD0	crc64:46F426AC0DFDFAD0	figure legend:Figure 5Dii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:g9F096gZXhiXDsPNkGW3UmU9xEU	false	mutation disrupting interaction strength:271-271	mutation disrupting interaction strength:271-271	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21651	uniprotkb:P21651	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Henderson et al. (2006)	imex:IM-26323|pubmed:16814718	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715794|imex:IM-26323-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:46F426AC0DFDFAD0	crc64:46F426AC0DFDFAD0	figure legend:Figure 5Diii|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:g9F096gZXhiXDsPNkGW3UmU9xEU	false	mutation disrupting interaction strength:30-30,271-271	mutation disrupting interaction strength:30-30,271-271	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32841	uniprotkb:P21651	intact:EBI-14447|uniprotkb:D6VZV6|ensemblfungi:YMR133W	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:re114_yeast(display_long)|uniprotkb:YM9375.02(orf name)|uniprotkb:YMR133W(locus name)|uniprotkb:REC114(gene name)|psi-mi:REC114(display_short)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Henderson et al. (2006)	imex:IM-26323|pubmed:16814718	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715812|imex:IM-26323-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR133W(gene)|ensemblfungi:YMR133W_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042138"(meiotic DNA double-strand break formation)|interpro:IPR004354(Meiotic recombination protein rec114)|refseq:NP_013852.1|sgd:S000004740|dip:DIP-4006N	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	-	crc64:46F426AC0DFDFAD0	figure legend:Figure 5E|comment:Meiosis-specific interaction.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:Ct+5dpxGmczgKzWhEhiHiRuxPG4559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:Cui17e+My6MeQtHvT7DhE6M2/6w	false	-	mutation with no effect:271-271|mutation disrupting interaction strength:30-30|mutation disrupting interaction strength:271-271,30-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P33301	uniprotkb:P21651	intact:EBI-20599|uniprotkb:D6VT00|ensemblfungi:YDR369C	intact:EBI-10742|ensemblfungi:YJR021C|uniprotkb:D6VWJ5	psi-mi:xrs2_yeast(display_long)|uniprotkb:XRS2(gene name)|psi-mi:XRS2(display_short)|uniprotkb:D9481.13(orf name)|uniprotkb:YDR369C(locus name)	psi-mi:re107_yeast(display_long)|uniprotkb:MER2(gene name synonym)|uniprotkb:J1462(orf name)|uniprotkb:YJR021C(locus name)|uniprotkb:REC107(gene name)|psi-mi:REC107(display_short)|uniprotkb:Meiotic recombination protein 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Henderson et al. (2006)	imex:IM-26323|pubmed:16814718	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-16715826|imex:IM-26323-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000002777|refseq:NP_010657.3|ensemblfungi:YDR369C(gene)|ensemblfungi:YDR369C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0030435"(sporulation resulting in formation of a cellular spore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0035753"(maintenance of DNA trinucleotide repeats)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|dip:DIP-2420N|mint:P33301	ensemblfungi:YJR021C(gene)|ensemblfungi:YJR021C_mRNA(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0042802"(identical protein binding)|interpro:IPR015159(Mer2)|sgd:S000003782|refseq:NP_012555.1|dip:DIP-5265N	-	crc64:833DAD6D20F6693E	crc64:46F426AC0DFDFAD0	figure legend:Figure 5F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/11/17	2017/12/21	rogid:o505mxGL67ZY1mBUls7e15A4JTY559292	rogid:v9kR3rBIptwb/cZE7B5IMAkYWKc559292	rigid:aGQTlAZfNc+OHtwAp0DYUkYnfTw	false	-	mutation decreasing interaction strength:271-271|mutation disrupting interaction strength:30-30|mutation disrupting interaction strength:271-271,30-30	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)