#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O96989 uniprotkb:Q9W2V7 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-15589005|ensemblmetazoa:FBpp0071399|ensemblmetazoa:FBpp0305498|ensemblmetazoa:FBpp0312067 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9w2v7_drome(display_long)|uniprotkb:Dmel\CG2222(gene name synonym)|uniprotkb:Psf3(gene name)|psi-mi:Psf3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:CG2222(orf name)|uniprotkb:Dmel_CG2222(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0030196(gene)|ensemblmetazoa:FBtr0071465(transcript)|ensemblmetazoa:FBtr0333306(transcript)|ensemblmetazoa:FBtr0346350(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|refseq:NP_001259406.1|refseq:NP_001285083.1|refseq:NP_572624.1|flybase:FBgn0030196|dip:DIP-59082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:gFkJGHxp8psu79oPCO67TxwW9Io7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:Q9VQY9 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:Q9W0I7 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-170577|ensemblmetazoa:FBpp0072615 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9w0i7_drome(display_long)|uniprotkb:Psf1(gene name)|psi-mi:Psf1(display_short)|uniprotkb:CG9187-PA(gene name synonym)|uniprotkb:Dmel\CG9187(gene name synonym)|uniprotkb:psf1(gene name synonym)|uniprotkb:Dmel_CG9187(orf name)|uniprotkb:CG9187(orf name)|uniprotkb:PSF1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_612086.1|flybase:FBgn0035194|ensemblmetazoa:FBgn0035194(gene)|ensemblmetazoa:FBtr0072731(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176974|rcsb pdb:6RAY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:h/3FkeXjvRZXTT7avIFYDsaEff07227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:Q9VBI1 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-124971|ensemblmetazoa:FBpp0084348 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9vbi1_drome(display_long)|uniprotkb:Sld5(gene name)|psi-mi:Sld5(display_short)|uniprotkb:Dmel\CG14549(gene name synonym)|uniprotkb:anon-WO0172774.61(gene name synonym)|uniprotkb:Dmel_CG14549(orf name)|uniprotkb:CG14549(orf name)|uniprotkb:SLD5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_651457.1|flybase:FBgn0039403|ensemblmetazoa:FBgn0039403(gene)|ensemblmetazoa:FBtr0084975(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:7nx+oL7xZsjl9lYlsgAtURcqwms7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:Q9XYU0 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-496657|intact:EBI-3407007|uniprotkb:P91674|ensemblmetazoa:FBpp0076312 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm7_drome(display_long)|uniprotkb:CG4978(orf name)|uniprotkb:Mcm7(gene name)|psi-mi:Mcm7(display_short)|uniprotkb:Minichromosome maintenance 7 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY go:"GO:0042555"(MCM complex)|refseq:NP_523984.1|flybase:FBgn0020633|dip:DIP-59081N|ensemblmetazoa:FBgn0020633(gene)|ensemblmetazoa:FBtr0076585(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|go:"GO:0071162"(CMG complex) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:ajuSGAnXtxuuXvn9CNxyg0DwNIY7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:Q9V461 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:Q9VGW6 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:Q26454 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:Q9XYU1 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96989 uniprotkb:P49735 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589026|imex:IM-23742-1|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9VQY9 uniprotkb:Q9W2V7 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-15589005|ensemblmetazoa:FBpp0071399|ensemblmetazoa:FBpp0305498|ensemblmetazoa:FBpp0312067 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:q9w2v7_drome(display_long)|uniprotkb:Dmel\CG2222(gene name synonym)|uniprotkb:Psf3(gene name)|psi-mi:Psf3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:CG2222(orf name)|uniprotkb:Dmel_CG2222(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N ensemblmetazoa:FBgn0030196(gene)|ensemblmetazoa:FBtr0071465(transcript)|ensemblmetazoa:FBtr0333306(transcript)|ensemblmetazoa:FBtr0346350(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|refseq:NP_001259406.1|refseq:NP_001285083.1|refseq:NP_572624.1|flybase:FBgn0030196|dip:DIP-59082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:gFkJGHxp8psu79oPCO67TxwW9Io7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:Q9W0I7 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-170577|ensemblmetazoa:FBpp0072615 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:q9w0i7_drome(display_long)|uniprotkb:Psf1(gene name)|psi-mi:Psf1(display_short)|uniprotkb:CG9187-PA(gene name synonym)|uniprotkb:Dmel\CG9187(gene name synonym)|uniprotkb:psf1(gene name synonym)|uniprotkb:Dmel_CG9187(orf name)|uniprotkb:CG9187(orf name)|uniprotkb:PSF1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N refseq:NP_612086.1|flybase:FBgn0035194|ensemblmetazoa:FBgn0035194(gene)|ensemblmetazoa:FBtr0072731(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176974|rcsb pdb:6RAY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:h/3FkeXjvRZXTT7avIFYDsaEff07227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:Q9VBI1 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-124971|ensemblmetazoa:FBpp0084348 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:q9vbi1_drome(display_long)|uniprotkb:Sld5(gene name)|psi-mi:Sld5(display_short)|uniprotkb:Dmel\CG14549(gene name synonym)|uniprotkb:anon-WO0172774.61(gene name synonym)|uniprotkb:Dmel_CG14549(orf name)|uniprotkb:CG14549(orf name)|uniprotkb:SLD5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N refseq:NP_651457.1|flybase:FBgn0039403|ensemblmetazoa:FBgn0039403(gene)|ensemblmetazoa:FBtr0084975(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:7nx+oL7xZsjl9lYlsgAtURcqwms7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:Q9XYU0 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-496657|intact:EBI-3407007|uniprotkb:P91674|ensemblmetazoa:FBpp0076312 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:mcm7_drome(display_long)|uniprotkb:CG4978(orf name)|uniprotkb:Mcm7(gene name)|psi-mi:Mcm7(display_short)|uniprotkb:Minichromosome maintenance 7 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N go:"GO:0042555"(MCM complex)|refseq:NP_523984.1|flybase:FBgn0020633|dip:DIP-59081N|ensemblmetazoa:FBgn0020633(gene)|ensemblmetazoa:FBtr0076585(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|go:"GO:0071162"(CMG complex) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:ajuSGAnXtxuuXvn9CNxyg0DwNIY7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:Q9V461 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:Q9VGW6 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:Q26454 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:Q9XYU1 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:P49735 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9VQY9 uniprotkb:O96989 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 intact:EBI-156880|ensemblmetazoa:FBpp0070175 psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589052|imex:IM-23742-2|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:Q9XYU0 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-496657|intact:EBI-3407007|uniprotkb:P91674|ensemblmetazoa:FBpp0076312 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm7_drome(display_long)|uniprotkb:CG4978(orf name)|uniprotkb:Mcm7(gene name)|psi-mi:Mcm7(display_short)|uniprotkb:Minichromosome maintenance 7 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589078|imex:IM-23742-3|dip:DIP-197812E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 go:"GO:0042555"(MCM complex)|refseq:NP_523984.1|flybase:FBgn0020633|dip:DIP-59081N|ensemblmetazoa:FBgn0020633(gene)|ensemblmetazoa:FBtr0076585(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|go:"GO:0071162"(CMG complex) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:ajuSGAnXtxuuXvn9CNxyg0DwNIY7227 rigid:V1BA5rX/rTQc7iyk2Uye6s24RhA false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:Q26454 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589078|imex:IM-23742-3|dip:DIP-197812E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 rigid:V1BA5rX/rTQc7iyk2Uye6s24RhA false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9V461 uniprotkb:P49735 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589078|imex:IM-23742-3|dip:DIP-197812E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rigid:V1BA5rX/rTQc7iyk2Uye6s24RhA false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9W2V7 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-15589005|ensemblmetazoa:FBpp0071399|ensemblmetazoa:FBpp0305498|ensemblmetazoa:FBpp0312067 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9w2v7_drome(display_long)|uniprotkb:Dmel\CG2222(gene name synonym)|uniprotkb:Psf3(gene name)|psi-mi:Psf3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:CG2222(orf name)|uniprotkb:Dmel_CG2222(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0030196(gene)|ensemblmetazoa:FBtr0071465(transcript)|ensemblmetazoa:FBtr0333306(transcript)|ensemblmetazoa:FBtr0346350(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|refseq:NP_001259406.1|refseq:NP_001285083.1|refseq:NP_572624.1|flybase:FBgn0030196|dip:DIP-59082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:gFkJGHxp8psu79oPCO67TxwW9Io7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9VQY9 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9W0I7 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-170577|ensemblmetazoa:FBpp0072615 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9w0i7_drome(display_long)|uniprotkb:Psf1(gene name)|psi-mi:Psf1(display_short)|uniprotkb:CG9187-PA(gene name synonym)|uniprotkb:Dmel\CG9187(gene name synonym)|uniprotkb:psf1(gene name synonym)|uniprotkb:Dmel_CG9187(orf name)|uniprotkb:CG9187(orf name)|uniprotkb:PSF1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_612086.1|flybase:FBgn0035194|ensemblmetazoa:FBgn0035194(gene)|ensemblmetazoa:FBtr0072731(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176974|rcsb pdb:6RAY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:h/3FkeXjvRZXTT7avIFYDsaEff07227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9VBI1 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-124971|ensemblmetazoa:FBpp0084348 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9vbi1_drome(display_long)|uniprotkb:Sld5(gene name)|psi-mi:Sld5(display_short)|uniprotkb:Dmel\CG14549(gene name synonym)|uniprotkb:anon-WO0172774.61(gene name synonym)|uniprotkb:Dmel_CG14549(orf name)|uniprotkb:CG14549(orf name)|uniprotkb:SLD5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_651457.1|flybase:FBgn0039403|ensemblmetazoa:FBgn0039403(gene)|ensemblmetazoa:FBtr0084975(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:7nx+oL7xZsjl9lYlsgAtURcqwms7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9XYU0 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-496657|intact:EBI-3407007|uniprotkb:P91674|ensemblmetazoa:FBpp0076312 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm7_drome(display_long)|uniprotkb:CG4978(orf name)|uniprotkb:Mcm7(gene name)|psi-mi:Mcm7(display_short)|uniprotkb:Minichromosome maintenance 7 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY go:"GO:0042555"(MCM complex)|refseq:NP_523984.1|flybase:FBgn0020633|dip:DIP-59081N|ensemblmetazoa:FBgn0020633(gene)|ensemblmetazoa:FBtr0076585(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|go:"GO:0071162"(CMG complex) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:ajuSGAnXtxuuXvn9CNxyg0DwNIY7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9V461 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9VGW6 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q26454 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9XYU1 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:P49735 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589099|imex:IM-23742-4|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9W2V7 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-15589005|ensemblmetazoa:FBpp0071399|ensemblmetazoa:FBpp0305498|ensemblmetazoa:FBpp0312067 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9w2v7_drome(display_long)|uniprotkb:Dmel\CG2222(gene name synonym)|uniprotkb:Psf3(gene name)|psi-mi:Psf3(display_short)|uniprotkb:PSF3(gene name synonym)|uniprotkb:CG2222(orf name)|uniprotkb:Dmel_CG2222(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0030196(gene)|ensemblmetazoa:FBtr0071465(transcript)|ensemblmetazoa:FBtr0333306(transcript)|ensemblmetazoa:FBtr0346350(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0071162"(CMG complex)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR010492(GINS complex, Psf3 component)|interpro:IPR021151|interpro:IPR036224|interpro:IPR038437|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|refseq:NP_001259406.1|refseq:NP_001285083.1|refseq:NP_572624.1|flybase:FBgn0030196|dip:DIP-59082N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:gFkJGHxp8psu79oPCO67TxwW9Io7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9VQY9 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-133591|uniprotkb:Q8SYY9|uniprotkb:M9PB28|ensemblmetazoa:FBpp0303866|ensemblmetazoa:FBpp0303867 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:psf2_drome(display_long)|uniprotkb:CG18013(orf name)|uniprotkb:GINS complex subunit 2(gene name synonym)|uniprotkb:Psf2(gene name)|psi-mi:Psf2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY flybase:FBgn0261976|refseq:NP_001260022.1|refseq:NP_608826.4|ensemblmetazoa:FBgn0261976(gene)|ensemblmetazoa:FBtr0331449(transcript)|ensemblmetazoa:FBtr0331450(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0005634"(nucleus)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0071162"(CMG complex)|interpro:IPR007257(GINS complex, Psf2 component)|interpro:IPR021151|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974|dip:DIP-61215N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:3brIGFNdbFt9CHBuQVjxFzArexI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9W0I7 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-170577|ensemblmetazoa:FBpp0072615 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9w0i7_drome(display_long)|uniprotkb:Psf1(gene name)|psi-mi:Psf1(display_short)|uniprotkb:CG9187-PA(gene name synonym)|uniprotkb:Dmel\CG9187(gene name synonym)|uniprotkb:psf1(gene name synonym)|uniprotkb:Dmel_CG9187(orf name)|uniprotkb:CG9187(orf name)|uniprotkb:PSF1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_612086.1|flybase:FBgn0035194|ensemblmetazoa:FBgn0035194(gene)|ensemblmetazoa:FBtr0072731(transcript)|go:"GO:0000811"(GINS complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071162"(CMG complex)|go:"GO:1902983"(DNA strand elongation involved in mitotic DNA replication)|interpro:IPR005339(GINS complex, Psf1 component)|interpro:IPR036224|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176974|rcsb pdb:6RAY psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:h/3FkeXjvRZXTT7avIFYDsaEff07227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9VBI1 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-124971|ensemblmetazoa:FBpp0084348 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:q9vbi1_drome(display_long)|uniprotkb:Sld5(gene name)|psi-mi:Sld5(display_short)|uniprotkb:Dmel\CG14549(gene name synonym)|uniprotkb:anon-WO0172774.61(gene name synonym)|uniprotkb:Dmel_CG14549(orf name)|uniprotkb:CG14549(orf name)|uniprotkb:SLD5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_651457.1|flybase:FBgn0039403|ensemblmetazoa:FBgn0039403(gene)|ensemblmetazoa:FBtr0084975(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000811"(GINS complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0071162"(CMG complex)|interpro:IPR008591(GINS complex, Sld5 component)|interpro:IPR021151|interpro:IPR031633|interpro:IPR036224|interpro:IPR038749|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176974 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:7nx+oL7xZsjl9lYlsgAtURcqwms7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9XYU0 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-496657|intact:EBI-3407007|uniprotkb:P91674|ensemblmetazoa:FBpp0076312 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm7_drome(display_long)|uniprotkb:CG4978(orf name)|uniprotkb:Mcm7(gene name)|psi-mi:Mcm7(display_short)|uniprotkb:Minichromosome maintenance 7 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY go:"GO:0042555"(MCM complex)|refseq:NP_523984.1|flybase:FBgn0020633|dip:DIP-59081N|ensemblmetazoa:FBgn0020633(gene)|ensemblmetazoa:FBtr0076585(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|go:"GO:0071162"(CMG complex) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:ajuSGAnXtxuuXvn9CNxyg0DwNIY7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9V461 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-869161|uniprotkb:O96047|uniprotkb:Q960E3|ensemblmetazoa:FBpp0070913 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm6_drome(display_long)|uniprotkb:Mcm6(gene name)|psi-mi:Mcm6(display_short)|uniprotkb:CG4039(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_511065.1|flybase:FBgn0025815|dip:DIP-35347N|ensemblmetazoa:FBgn0025815(gene)|ensemblmetazoa:FBtr0070952(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0007307"(eggshell chorion gene amplification)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|interpro:IPR001208(MCM)|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:FfPtMWvmJiDc7GZqUvNIWgul6sY7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9VGW6 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-83298|ensemblmetazoa:FBpp0081756|intact:EBI-466357|uniprotkb:P91676 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm5_drome(display_long)|uniprotkb:Mcm5(gene name)|psi-mi:Mcm5(display_short)|uniprotkb:CG4082(orf name)|uniprotkb:Minichromosome maintenance 5 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0017577(gene)|ensemblmetazoa:FBtr0082279(transcript)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0042555"(MCM complex)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|interpro:IPR001208(MCM)|interpro:IPR008048(MCM protein 5)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|refseq:NP_524308.2|flybase:FBgn0017577 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:pE+5Qt9rUBjQz997MqFx67cZ/vI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q26454 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-175772|uniprotkb:Q9V4M5|ensemblmetazoa:FBpp0088055|ensemblmetazoa:FBpp0311783 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm4_drome(display_long)|uniprotkb:dpa(gene name)|psi-mi:dpa(display_short)|uniprotkb:CG1616(orf name)|uniprotkb:Protein disc proliferation abnormal(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_477185.1|flybase:FBgn0015929|refseq:NP_001286160.1|dip:DIP-35346N|ensemblmetazoa:FBgn0015929(gene)|ensemblmetazoa:FBtr0088982(transcript)|ensemblmetazoa:FBtr0345797(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008047(MCM protein 4)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR036388|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:NPLqbZqr627OjOQE1CaH1sUgciI7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:Q9XYU1 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-103930|intact:EBI-870177|uniprotkb:P91675|ensemblmetazoa:FBpp0070729 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm3_drome(display_long)|uniprotkb:Mcm3(gene name)|psi-mi:Mcm3(display_short)|uniprotkb:CG4206(orf name)|uniprotkb:Mcm3-RA(gene name synonym)|uniprotkb:Minichromosome maintenance 3 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY refseq:NP_511048.2|ensemblmetazoa:FBgn0284442(gene)|ensemblmetazoa:FBtr0070762(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008046(MCM protein 3)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|interpro:IPR031327|flybase:FBgn0284442 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:5fIRUuyA2wXZ3n97xi9cAk2ZDQQ7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96989 uniprotkb:P49735 intact:EBI-156880|ensemblmetazoa:FBpp0070175 intact:EBI-138228|uniprotkb:Q9VHU2|ensemblmetazoa:FBpp0081317 psi-mi:o96989_drome(display_long)|uniprotkb:Cdc45(gene name)|psi-mi:Cdc45(display_short)|uniprotkb:CDC45(gene name synonym)|uniprotkb:CDC45L(gene name synonym)|uniprotkb:D(gene name synonym)|uniprotkb:DmCdc45(gene name synonym)|uniprotkb:Dmel\CG3658(gene name synonym)|uniprotkb:"EG:BACR7A4.11"(gene name synonym)|uniprotkb:anon-1Ec(gene name synonym)|uniprotkb:cdc45(gene name synonym)|uniprotkb:dCDC45(gene name synonym)|uniprotkb:dCDC45L(gene name synonym)|uniprotkb:CG3658(orf name)|uniprotkb:Dmel_CG3658(orf name) psi-mi:mcm2_drome(display_long)|uniprotkb:Mcm2(gene name)|psi-mi:Mcm2(display_short)|uniprotkb:CG7538(orf name)|uniprotkb:Minichromosome maintenance 2 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Moyer et al. (2006) pubmed:16798881|doi:10.1073/pnas.0602400103|imex:IM-23742 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15589125|imex:IM-23742-5|dip:DIP-197811E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_569880.1|flybase:FBgn0026143|dip:DIP-20144N|ensemblmetazoa:FBgn0026143(gene)|ensemblmetazoa:FBtr0070182(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006277"(DNA amplification)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:1902977"(mitotic DNA replication preinitiation complex assembly)|interpro:IPR003874(CDC45-like protein)|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68962|rcsb pdb:6RAY ensemblmetazoa:FBgn0014861(gene)|ensemblmetazoa:FBtr0081827(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0030261"(chromosome condensation)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|rcsb pdb:6RAW|rcsb pdb:6RAX|rcsb pdb:6RAY|rcsb pdb:6RAZ|reactome:R-DME-176187|reactome:R-DME-68867|reactome:R-DME-68949|reactome:R-DME-68962|reactome:R-DME-69052|refseq:NP_477121.1|flybase:FBgn0014861|dip:DIP-22529N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") - 2017/08/05 2017/08/10 rogid:/ivfSBShEpXOtbuOiXeQKg+9EC07227 rogid:Jnb71nPH/PDF5xcA8kTakW8zhDE7227 rigid:yhUCunvE1QAfvzouEhPTlhzm1QM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)