#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P10276 uniprotkb:P51946 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gaillard et al. (2006) pubmed:16769902|doi:10.1073/pnas.0509717103|imex:IM-23632 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15586616|imex:IM-23632-1|dip:DIP-197727E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:7108(spofr)|taxid:7108("Spodoptera frugiperda (Fall armyworm)") - 2017/08/05 2017/08/10 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606 rigid:hb/7uD1ljQOPIEHw933J7Fz9BAs false flag tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10276 uniprotkb:P51946 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-741406|uniprotkb:Q8TBL9|uniprotkb:Q53X72|intact:EBI-28985782|ensembl:ENSP00000256897 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:ccnh_human(display_long)|uniprotkb:MO15-associated protein(gene name synonym)|uniprotkb:p37(gene name synonym)|uniprotkb:p34(gene name synonym)|uniprotkb:CCNH(gene name)|psi-mi:CCNH(display_short) psi-mi:"MI:0096"(pull down) Gaillard et al. (2006) pubmed:16769902|doi:10.1073/pnas.0509717103|imex:IM-23632 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15586635|imex:IM-23632-2|dip:DIP-197727E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N refseq:NP_001230.1|ensembl:ENSG00000134480(gene)|ensembl:ENST00000256897(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019907"(cyclin-dependent protein kinase activating kinase holoenzyme complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0070516"(CAK-ERCC2 complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0070985"(transcription factor TFIIK complex)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR027081|interpro:IPR031658|interpro:IPR036915|interpro:IPR043198|rcsb pdb:1JKW|rcsb pdb:1KXU|rcsb pdb:6O9L|rcsb pdb:6XBZ|rcsb pdb:6XD3|rcsb pdb:7B5O|rcsb pdb:7B5Q|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-69656|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8939236|ensembl:ENSP00000256897|dip:DIP-5996N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:OORqAxdGyjEcCe38DaFXd7BwjxI9606 rigid:hb/7uD1ljQOPIEHw933J7Fz9BAs false glutathione s tranferase tag:n-n - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19793 uniprotkb:P10276 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0096"(pull down) Gaillard et al. (2006) pubmed:16769902|doi:10.1073/pnas.0509717103|imex:IM-23632 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15586654|imex:IM-23632-3|dip:DIP-1003E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29 refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/05 2017/08/10 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rigid:71FF0ybMB6wwiKTAJbWyoX6Eo7I false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)