#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P40995	uniprotkb:P08647	intact:EBI-15585304|ensemblfungi:"SPAC16E8.09.1:pep"	intact:EBI-15585264|ensemblfungi:"SPAC17H9.09c.1:pep"|uniprotkb:O13806	psi-mi:scd1_schpo(display_long)|uniprotkb:scd1(gene name)|psi-mi:scd1(display_short)|uniprotkb:ral1(gene name synonym)|uniprotkb:SPAC16E8.09(orf name)	psi-mi:ras_schpo(display_long)|uniprotkb:ras1(gene name)|psi-mi:ras1(display_short)|uniprotkb:SPAC17H9.09c(orf name)	psi-mi:"MI:0018"(two hybrid)	Onken et al. (2006)	pubmed:16754851|doi:10.1073/pnas.0603318103|imex:IM-23625	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15585343|imex:IM-23625-1|dip:DIP-197716E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:SPAC16E8.09(gene)|ensemblfungi:SPAC16E8.09.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000917"(division septum assembly)|go:"GO:0000935"(division septum)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008289"(lipid binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030427"(site of polarized growth)|go:"GO:0031106"(septin ring organization)|go:"GO:0031520"(plasma membrane of cell tip)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032955"(regulation of division septum assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043332"(mating projection tip)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0051286"(cell tip)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0061246"(establishment or maintenance of bipolar cell polarity regulating cell shape)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1901891"(regulation of cell septum assembly)|go:"GO:1902432"(protein localization to division septum)|go:"GO:1902716"(cell cortex of growing cell tip)|go:"GO:1902917"(positive regulation of mating projection assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010481(CDC24 calponin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033511|interpro:IPR035899|refseq:NP_594221.1|dip:DIP-44893N	ensemblfungi:SPAC17H9.09c(gene)|ensemblfungi:SPAC17H9.09c.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000935"(division septum)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0019003"(GDP binding)|go:"GO:0031139"(positive regulation of conjugation with cellular fusion)|go:"GO:0032005"(signal transduction involved in positive regulation of conjugation with cellular fusion)|go:"GO:0032153"(cell division site)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0062038"(positive regulation of pheromone response MAPK cascade)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:1990819"(actin fusion focus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-SPO-9696273|refseq:NP_593579.1|dip:DIP-61182N	psi-mi:"MI:0465"(dip)	crc64:726FAE33B519D69D	crc64:109A0C468663F535	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:BURMTHDhn8aOy9FyV86/Mv7yRCg284812	rogid:rHR9wJ5hClKDly819yXnamRP1Mg284812	rigid:OX0bf6JU75TkJSBAsxLljWu5lsg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28829	uniprotkb:P08647	intact:EBI-1032333|uniprotkb:Q7LGJ0|ensemblfungi:"SPBC1D7.05.1:pep"	intact:EBI-15585264|ensemblfungi:"SPAC17H9.09c.1:pep"|uniprotkb:O13806	psi-mi:byr2_schpo(display_long)|uniprotkb:byr2(gene name)|psi-mi:byr2(display_short)|uniprotkb:ste8(gene name synonym)|uniprotkb:SPBC1D7.05(orf name)|uniprotkb:SPBC2F12.01(orf name)|uniprotkb:Protein kinase ste8(gene name synonym)|uniprotkb:MAPK kinase kinase(gene name synonym)	psi-mi:ras_schpo(display_long)|uniprotkb:ras1(gene name)|psi-mi:ras1(display_short)|uniprotkb:SPAC17H9.09c(orf name)	psi-mi:"MI:0018"(two hybrid)	Onken et al. (2006)	pubmed:16754851|doi:10.1073/pnas.0603318103|imex:IM-23625	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15585360|imex:IM-23625-2|dip:DIP-197717E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_595714.2|go:"GO:0000935"(division septum)|go:"GO:0004672"(protein kinase activity)|ensemblfungi:SPBC1D7.05(gene)|ensemblfungi:SPBC1D7.05.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010514"(induction of conjugation with cellular fusion)|go:"GO:0032153"(cell division site)|go:"GO:0051286"(cell tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|interpro:IPR029458|rcsb pdb:1I35|rcsb pdb:1K8R|go:"GO:0004709"(MAP kinase kinase kinase activity)|reactome:R-SPO-2559580|dip:DIP-136N	ensemblfungi:SPAC17H9.09c(gene)|ensemblfungi:SPAC17H9.09c.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000935"(division septum)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0019003"(GDP binding)|go:"GO:0031139"(positive regulation of conjugation with cellular fusion)|go:"GO:0032005"(signal transduction involved in positive regulation of conjugation with cellular fusion)|go:"GO:0032153"(cell division site)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0062038"(positive regulation of pheromone response MAPK cascade)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:1990819"(actin fusion focus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-SPO-9696273|refseq:NP_593579.1|dip:DIP-61182N	psi-mi:"MI:0465"(dip)	crc64:18CD78F1D1FABBCD	crc64:109A0C468663F535	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:prELfaSlVM0CwN9fAyr+XVwi3Iw284812	rogid:rHR9wJ5hClKDly819yXnamRP1Mg284812	rigid:Bxf7935+YFJeq6COW1QBOHWunoY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P28829	uniprotkb:P08647	intact:EBI-1032333|uniprotkb:Q7LGJ0|ensemblfungi:"SPBC1D7.05.1:pep"	intact:EBI-15585264|ensemblfungi:"SPAC17H9.09c.1:pep"|uniprotkb:O13806	psi-mi:byr2_schpo(display_long)|uniprotkb:byr2(gene name)|psi-mi:byr2(display_short)|uniprotkb:ste8(gene name synonym)|uniprotkb:SPBC1D7.05(orf name)|uniprotkb:SPBC2F12.01(orf name)|uniprotkb:Protein kinase ste8(gene name synonym)|uniprotkb:MAPK kinase kinase(gene name synonym)	psi-mi:ras_schpo(display_long)|uniprotkb:ras1(gene name)|psi-mi:ras1(display_short)|uniprotkb:SPAC17H9.09c(orf name)	psi-mi:"MI:0096"(pull down)	Onken et al. (2006)	pubmed:16754851|doi:10.1073/pnas.0603318103|imex:IM-23625	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15585377|imex:IM-23625-3|dip:DIP-197717E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_595714.2|go:"GO:0000935"(division septum)|go:"GO:0004672"(protein kinase activity)|ensemblfungi:SPBC1D7.05(gene)|ensemblfungi:SPBC1D7.05.1(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010514"(induction of conjugation with cellular fusion)|go:"GO:0032153"(cell division site)|go:"GO:0051286"(cell tip)|go:"GO:0071507"(pheromone response MAPK cascade)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR029071|interpro:IPR029458|rcsb pdb:1I35|rcsb pdb:1K8R|go:"GO:0004709"(MAP kinase kinase kinase activity)|reactome:R-SPO-2559580|dip:DIP-136N	ensemblfungi:SPAC17H9.09c(gene)|ensemblfungi:SPAC17H9.09c.1(transcript)|go:"GO:0000747"(conjugation with cellular fusion)|go:"GO:0000935"(division septum)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0019003"(GDP binding)|go:"GO:0031139"(positive regulation of conjugation with cellular fusion)|go:"GO:0032005"(signal transduction involved in positive regulation of conjugation with cellular fusion)|go:"GO:0032153"(cell division site)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0051285"(cell cortex of cell tip)|go:"GO:0062038"(positive regulation of pheromone response MAPK cascade)|go:"GO:0071521"(Cdc42 GTPase complex)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090726"(cortical dynamic polarity patch)|go:"GO:1902917"(positive regulation of mating projection assembly)|go:"GO:1990819"(actin fusion focus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|reactome:R-SPO-9696273|refseq:NP_593579.1|dip:DIP-61182N	psi-mi:"MI:0465"(dip)	crc64:18CD78F1D1FABBCD	crc64:109A0C468663F535	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:prELfaSlVM0CwN9fAyr+XVwi3Iw284812	rogid:rHR9wJ5hClKDly819yXnamRP1Mg284812	rigid:Bxf7935+YFJeq6COW1QBOHWunoY	false	glutathione s tranferase tag:n-n	t7 tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)