#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q62768	uniprotkb:Q62768	intact:EBI-15584670	intact:EBI-15584670	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Lu et al. (2006)	pubmed:16732694|doi:10.1371/journal.pbio.0040192|imex:IM-8523	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15584728|imex:IM-8523-7|dip:DIP-57207E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rigid:Dagl3P9HDWNWq//Fbl1Ppiy0mCU	false	sufficient binding region:3-150	sufficient binding region:3-150	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62768	uniprotkb:Q62768	intact:EBI-15584670	intact:EBI-15584670	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Lu et al. (2006)	pubmed:16732694|doi:10.1371/journal.pbio.0040192|imex:IM-8523	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15584746|imex:IM-8523-6|dip:DIP-57207E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rigid:Dagl3P9HDWNWq//Fbl1Ppiy0mCU	false	sufficient binding region:3-150	sufficient binding region:3-150	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9JIS1	uniprotkb:Q62768	intact:EBI-6972631|uniprotkb:Q9JIR6|uniprotkb:Q9JIR8|intact:MINT-270417|uniprotkb:Q9JIS0|uniprotkb:Q9JIR7|uniprotkb:Q8CIX2|uniprotkb:Q9JIR5|uniprotkb:Q9JIR2|uniprotkb:Q9JIR9|uniprotkb:Q9JHJ6	intact:EBI-15584670	psi-mi:rims2_rat(display_long)|uniprotkb:Rims2(gene name)|psi-mi:Rims2(display_short)|uniprotkb:Rim2(gene name synonym)|uniprotkb:Rab-3-interacting molecule 2(gene name synonym)	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Lu et al. (2006)	pubmed:16732694|doi:10.1371/journal.pbio.0040192|imex:IM-8523	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15584803|imex:IM-8523-2|dip:DIP-57208E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR041489|rcsb pdb:2A20|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|rcsb pdb:2CJS|rcsb pdb:2BWQ|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0030154"(cell differentiation)|refseq:NP_665888.1|rgd:620001|refseq:NP_446397.1|dip:DIP-29192N	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	psi-mi:"MI:0465"(dip)	comment:mint|function:Rab effector involved in exocytosis. May act as scaffold protein	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:yKnqelJ4Bm6Zt4mLtVRWUDR1c5Y10116	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rigid:oFC0pcyon3brKSGMP85hLhMwKWs	false	sufficient binding region:82-142	sufficient binding region:3-150	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9JIS1	uniprotkb:Q62768	intact:EBI-6972631|uniprotkb:Q9JIR6|uniprotkb:Q9JIR8|intact:MINT-270417|uniprotkb:Q9JIS0|uniprotkb:Q9JIR7|uniprotkb:Q8CIX2|uniprotkb:Q9JIR5|uniprotkb:Q9JIR2|uniprotkb:Q9JIR9|uniprotkb:Q9JHJ6	intact:EBI-15584670	psi-mi:rims2_rat(display_long)|uniprotkb:Rims2(gene name)|psi-mi:Rims2(display_short)|uniprotkb:Rim2(gene name synonym)|uniprotkb:Rab-3-interacting molecule 2(gene name synonym)	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Lu et al. (2006)	pubmed:16732694|doi:10.1371/journal.pbio.0040192|imex:IM-8523	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15584824|imex:IM-8523-3|dip:DIP-57208E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR041489|rcsb pdb:2A20|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|rcsb pdb:2CJS|rcsb pdb:2BWQ|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0030154"(cell differentiation)|refseq:NP_665888.1|rgd:620001|refseq:NP_446397.1|dip:DIP-29192N	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	psi-mi:"MI:0465"(dip)	comment:mint|function:Rab effector involved in exocytosis. May act as scaffold protein	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:yKnqelJ4Bm6Zt4mLtVRWUDR1c5Y10116	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rigid:oFC0pcyon3brKSGMP85hLhMwKWs	false	sufficient binding region:82-142	sufficient binding region:3-150	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62768	uniprotkb:Q62768	intact:EBI-15584670	intact:EBI-15584670	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Lu et al. (2006)	pubmed:16732694|doi:10.1371/journal.pbio.0040192|imex:IM-8523	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15584845|imex:IM-8523-5|dip:DIP-57207E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rigid:Dagl3P9HDWNWq//Fbl1Ppiy0mCU	false	sufficient binding region:3-150|15n label:?-?	sufficient binding region:3-150|15n label:?-?	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62768	uniprotkb:Q62768	intact:EBI-15584670	intact:EBI-15584670	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Lu et al. (2006)	pubmed:16732694|doi:10.1371/journal.pbio.0040192|imex:IM-8523	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15584785|imex:IM-8523-8|dip:DIP-57207E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rigid:Dagl3P9HDWNWq//Fbl1Ppiy0mCU	false	sufficient binding region:3-150	sufficient binding region:3-150	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9JIS1	uniprotkb:Q62768	intact:EBI-6972631|uniprotkb:Q9JIR6|uniprotkb:Q9JIR8|intact:MINT-270417|uniprotkb:Q9JIS0|uniprotkb:Q9JIR7|uniprotkb:Q8CIX2|uniprotkb:Q9JIR5|uniprotkb:Q9JIR2|uniprotkb:Q9JIR9|uniprotkb:Q9JHJ6	intact:EBI-15584670	psi-mi:rims2_rat(display_long)|uniprotkb:Rims2(gene name)|psi-mi:Rims2(display_short)|uniprotkb:Rim2(gene name synonym)|uniprotkb:Rab-3-interacting molecule 2(gene name synonym)	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Lu et al. (2006)	pubmed:16732694|doi:10.1371/journal.pbio.0040192|imex:IM-8523	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15584764|imex:IM-8523-1|dip:DIP-57208E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR041489|rcsb pdb:2A20|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|rcsb pdb:2CJS|rcsb pdb:2BWQ|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0030154"(cell differentiation)|refseq:NP_665888.1|rgd:620001|refseq:NP_446397.1|dip:DIP-29192N	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	psi-mi:"MI:0465"(dip)	comment:mint|function:Rab effector involved in exocytosis. May act as scaffold protein	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:yKnqelJ4Bm6Zt4mLtVRWUDR1c5Y10116	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rigid:oFC0pcyon3brKSGMP85hLhMwKWs	false	sufficient binding region:82-142	sufficient binding region:3-150	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9JIS1	uniprotkb:Q62768	intact:EBI-6972631|uniprotkb:Q9JIR6|uniprotkb:Q9JIR8|intact:MINT-270417|uniprotkb:Q9JIS0|uniprotkb:Q9JIR7|uniprotkb:Q8CIX2|uniprotkb:Q9JIR5|uniprotkb:Q9JIR2|uniprotkb:Q9JIR9|uniprotkb:Q9JHJ6	intact:EBI-15584670	psi-mi:rims2_rat(display_long)|uniprotkb:Rims2(gene name)|psi-mi:Rims2(display_short)|uniprotkb:Rim2(gene name synonym)|uniprotkb:Rab-3-interacting molecule 2(gene name synonym)	psi-mi:un13a_rat(display_long)|uniprotkb:Unc13a(gene name)|psi-mi:Unc13a(display_short)|uniprotkb:Unc13h1(gene name synonym)|uniprotkb:Munc13-1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Lu et al. (2006)	pubmed:16732694|doi:10.1371/journal.pbio.0040192|imex:IM-8523	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15584867|imex:IM-8523-4|dip:DIP-57208E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR041489|rcsb pdb:2A20|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|rcsb pdb:2CJS|rcsb pdb:2BWQ|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0030154"(cell differentiation)|refseq:NP_665888.1|rgd:620001|refseq:NP_446397.1|dip:DIP-29192N	go:"GO:0043195"(terminal bouton)|go:"GO:0044305"(calyx of Held)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0061789"(dense core granule priming)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099011"(neuronal dense core vesicle exocytosis)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|go:"GO:0031594"(neuromuscular junction)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR014772(Munc13 homology 2)|interpro:IPR019558|interpro:IPR027080|interpro:IPR027082|interpro:IPR035892|interpro:IPR037302|rcsb pdb:1Y8F|rcsb pdb:2CJS|rcsb pdb:2CJT|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032991"(protein-containing complex)|rcsb pdb:2KDU|rcsb pdb:3SWH|rcsb pdb:4Y21|rcsb pdb:5UE8|rcsb pdb:5UF7|rcsb pdb:6A30|rcsb pdb:6NYC|rcsb pdb:6NYT|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|dip:DIP-29191N|refseq:NP_074052.1|rgd:619722	psi-mi:"MI:0465"(dip)	comment:mint|function:Rab effector involved in exocytosis. May act as scaffold protein	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:yKnqelJ4Bm6Zt4mLtVRWUDR1c5Y10116	rogid:47i2BPxBp9aBXygms61TXb56SgU10116	rigid:oFC0pcyon3brKSGMP85hLhMwKWs	false	sufficient binding region:82-142	sufficient binding region:3-150|15n label:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)