#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-15583943 uniprotkb:Q9ESK4 dip:DIP-60323N intact:EBI-1561388|uniprotkb:Q80VI5|uniprotkb:Q8BGU8|uniprotkb:Q4VAD7|ensembl:ENSMUSP00000079226 psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:ing2_mouse(display_long)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:Ing2(gene name)|psi-mi:Ing2(display_short)|uniprotkb:Ing1l(gene name synonym) psi-mi:"MI:0096"(pull down) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15583948|imex:IM-21624-1|dip:DIP-192050E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_075992.2|dip:DIP-38912N|ensembl:ENSMUSG00000063049(gene)|ensembl:ENSMUST00000080353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|rcsb pdb:1WES|rcsb pdb:2G6Q|reactome:R-MMU-3899300|reactome:R-MMU-6811555 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rogid:9pxLKzNNiUMtG+a2Z4SLTaiaUNQ10090 rigid:acr1GMcf+BykXqTa/JUCK9Kv+y0 false N6,N6,N6-trimethyl-L-lysine:4-4|N6,N6-dimethyl-L-lysine:4-4|biotin tag:0-0 mutation disrupting interaction strength:215-215|mutation disrupting interaction strength:238-238,237-237|sufficient binding region:205-265 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38806 intact:EBI-15583943 intact:EBI-24622|uniprotkb:D3DL42|ensemblfungi:YHR090C dip:DIP-60323N psi-mi:yng2_yeast(display_long)|uniprotkb:YHR090C(locus name)|uniprotkb:YNG2(gene name)|psi-mi:YNG2(display_short)|uniprotkb:EAF4(gene name synonym)|uniprotkb:NBN1(gene name synonym)|uniprotkb:ING1 homolog 2(gene name synonym)|uniprotkb:ESA1-associated factor 4(gene name synonym) psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584024|imex:IM-21624-4|dip:DIP-192056E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_011958.1|sgd:S000001132|dip:DIP-2095N|mint:P38806|ensemblfungi:YHR090C(gene)|ensemblfungi:YHR090C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0016573"(histone acetylation)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028651|rcsb pdb:2MUM|rcsb pdb:5J9Q|rcsb pdb:5J9T|rcsb pdb:5J9U|rcsb pdb:5J9W|reactome:R-SCE-3214847|reactome:R-SCE-3899300|reactome:R-SCE-6804758|reactome:R-SCE-6811555 - psi-mi:"MI:0465"(dip) crc64:110E0A2536547D03 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:f+JMrheLibmbLpo1xYMeGUTXBGY559292 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rigid:qyLj/DbpkIIaOjlucU8vNYnkj7k false sufficient binding region:222-271 N6,N6,N6-trimethyl-L-lysine:4-4 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15583943 uniprotkb:Q9ESK4 dip:DIP-60323N intact:EBI-1561388|uniprotkb:Q80VI5|uniprotkb:Q8BGU8|uniprotkb:Q4VAD7|ensembl:ENSMUSP00000079226 psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:ing2_mouse(display_long)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:Ing2(gene name)|psi-mi:Ing2(display_short)|uniprotkb:Ing1l(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584003|imex:IM-21624-3|dip:DIP-192050E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_075992.2|dip:DIP-38912N|ensembl:ENSMUSG00000063049(gene)|ensembl:ENSMUST00000080353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|rcsb pdb:1WES|rcsb pdb:2G6Q|reactome:R-MMU-3899300|reactome:R-MMU-6811555 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rogid:9pxLKzNNiUMtG+a2Z4SLTaiaUNQ10090 rigid:acr1GMcf+BykXqTa/JUCK9Kv+y0 false N6,N6,N6-trimethyl-L-lysine:4-4 sufficient binding region:205-265 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8WYH8 intact:EBI-15583943 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 dip:DIP-60323N psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15583981|imex:IM-21624-2|dip:DIP-192052E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rigid:yKwuo0b5FfUiOSyYYdGQ9u3RW0E false sufficient binding region:186-235 N6,N6,N6-trimethyl-L-lysine:4-4 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15583943 uniprotkb:Q9ESK4 dip:DIP-60323N intact:EBI-1561388|uniprotkb:Q80VI5|uniprotkb:Q8BGU8|uniprotkb:Q4VAD7|ensembl:ENSMUSP00000079226 psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:ing2_mouse(display_long)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:Ing2(gene name)|psi-mi:Ing2(display_short)|uniprotkb:Ing1l(gene name synonym) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584130|imex:IM-21624-9|dip:DIP-192050E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_075992.2|dip:DIP-38912N|ensembl:ENSMUSG00000063049(gene)|ensembl:ENSMUST00000080353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|rcsb pdb:1WES|rcsb pdb:2G6Q|reactome:R-MMU-3899300|reactome:R-MMU-6811555 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rogid:9pxLKzNNiUMtG+a2Z4SLTaiaUNQ10090 rigid:acr1GMcf+BykXqTa/JUCK9Kv+y0 false N6,N6,N6-trimethyl-L-lysine:4-4|N6,N6-dimethyl-L-lysine:4-4|monomethylated L-lysine:4-4 mutation decreasing interaction strength:238-238,237-237|mutation decreasing interaction strength:225-225,223-223|mutation disrupting interaction strength:215-215|mutation decreasing interaction strength:230-230|sufficient binding region:205-265 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9UK53 intact:EBI-15583943 intact:EBI-399198|uniprotkb:O00532|uniprotkb:O43658|uniprotkb:Q9H007|uniprotkb:Q9HD98|uniprotkb:Q9HD99|uniprotkb:Q9NS83|uniprotkb:Q9P0U6|uniprotkb:Q9UBC6|uniprotkb:Q9UIJ1|uniprotkb:Q9UIJ2|uniprotkb:Q9UIJ3|uniprotkb:Q9UIJ4|uniprotkb:Q9UK52|uniprotkb:Q53ZR3|uniprotkb:Q5T9H0|uniprotkb:Q5T9G8|uniprotkb:Q5T9H1|uniprotkb:Q5T9G9 dip:DIP-60323N psi-mi:ing1_human(display_long)|uniprotkb:ING1(gene name)|psi-mi:ING1(display_short) psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584108|imex:IM-21624-8|dip:DIP-192051E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_937860.1|refseq:NP_937861.1|refseq:NP_937862.1|refseq:NP_001254657.1|mint:Q9UK53|refseq:NP_005528.4|dip:DIP-24256N|dip:DIP-24257N|dip:DIP-24258N|interpro:IPR019786|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR024610|interpro:IPR028643|interpro:IPR028651|rcsb pdb:2QIC|go:"GO:0005634"(nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010941"(regulation of cell death)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type) - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:AQtE1tLKo5QG/aU6spQzOR5AjLw9606 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rigid:SADvo0JgeovF0Ew1bGEoh+L8Imw false sufficient binding region:353-402 N6,N6,N6-trimethyl-L-lysine:4-4 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15583943 uniprotkb:Q9ESK4 dip:DIP-60323N intact:EBI-1561388|uniprotkb:Q80VI5|uniprotkb:Q8BGU8|uniprotkb:Q4VAD7|ensembl:ENSMUSP00000079226 psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:ing2_mouse(display_long)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:Ing2(gene name)|psi-mi:Ing2(display_short)|uniprotkb:Ing1l(gene name synonym) psi-mi:"MI:0077"(nuclear magnetic resonance) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584087|imex:IM-21624-7|dip:DIP-192050E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_075992.2|dip:DIP-38912N|ensembl:ENSMUSG00000063049(gene)|ensembl:ENSMUST00000080353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|rcsb pdb:1WES|rcsb pdb:2G6Q|reactome:R-MMU-3899300|reactome:R-MMU-6811555 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rogid:9pxLKzNNiUMtG+a2Z4SLTaiaUNQ10090 rigid:acr1GMcf+BykXqTa/JUCK9Kv+y0 false N6,N6,N6-trimethyl-L-lysine:4-4 sufficient binding region:205-265 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9NXR8 intact:EBI-15583943 intact:EBI-769503|uniprotkb:O60394|uniprotkb:Q6GMT3|uniprotkb:Q7Z762|uniprotkb:Q969G0|uniprotkb:Q96DT4|uniprotkb:Q9HC99|uniprotkb:Q9P081|uniprotkb:A8K790|uniprotkb:Q567P3|ensembl:ENSP00000320566 dip:DIP-60323N psi-mi:ing3_human(display_long)|uniprotkb:p47ING3(gene name synonym)|uniprotkb:ING3(gene name)|psi-mi:ING3(display_short)|uniprotkb:HSPC301(orf name) psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584066|imex:IM-21624-6|dip:DIP-192053E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_061944.2|refseq:NP_938008.1|ensembl:ENSP00000320566|ensembl:ENST00000339121|ensembl:ENSP00000341697|ensembl:ENST00000427726|ensembl:ENSP00000410406|dip:DIP-34303N|ensembl:ENSG00000071243(gene)|ensembl:ENST00000315870(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032777"(Piccolo NuA4 histone acetyltransferase complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028651|interpro:IPR038004|interpro:IPR042020|rcsb pdb:1X4I|reactome:R-HSA-3214847 - psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:tWiu5AK7KDRDmvab4BGuUaZ/sfc9606 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rigid:zbpiz3dKzhUBzlbZW+b6ExyfI1c false sufficient binding region:360-409 N6,N6,N6-trimethyl-L-lysine:4-4 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50947 intact:EBI-15583943 intact:EBI-28808|uniprotkb:Q45TZ9|uniprotkb:D6W183|ensemblfungi:YNL097C dip:DIP-60323N psi-mi:pho23_yeast(display_long)|uniprotkb:PHO23(gene name)|psi-mi:PHO23(display_short)|uniprotkb:N2205(orf name)|uniprotkb:YNL097C(locus name) psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584169|imex:IM-21624-10|dip:DIP-192057E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) sgd:S000005041|refseq:NP_014302.3|dip:DIP-4243N|mint:P50947|ensemblfungi:YNL097C(gene)|ensemblfungi:YNL097C_mRNA(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0016573"(histone acetylation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:2000219"(positive regulation of invasive growth in response to glucose limitation)|go:"GO:2001159"(regulation of protein localization by the Cvt pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028651|reactome:R-SCE-3214847|reactome:R-SCE-3899300|reactome:R-SCE-6804758|reactome:R-SCE-6811555 - psi-mi:"MI:0465"(dip) crc64:3BF7B519E77ED6EF - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:N8KCC01xvIWGV9jdfQ/ZzizkIws559292 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rigid:2lislJF096Mxan8ingL98Y4dVhg false sufficient binding region:280-329 N6,N6,N6-trimethyl-L-lysine:4-4 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-15583943 uniprotkb:Q9UNL4 dip:DIP-60323N intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584045|imex:IM-21624-5|dip:DIP-192054E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rigid:tN7EzZwoLWkq4aeGYDE9n4cLQNQ false N6,N6,N6-trimethyl-L-lysine:4-4 sufficient binding region:196-245 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q08465 intact:EBI-15583943 intact:EBI-31890|uniprotkb:O00025|uniprotkb:D6W2C7|ensemblfungi:YOR064C dip:DIP-60323N psi-mi:yng1_yeast(display_long)|uniprotkb:ING1 homolog 1(gene name synonym)|uniprotkb:YNG1(gene name)|psi-mi:YNG1(display_short)|uniprotkb:YOR29-15(orf name)|uniprotkb:YOR064C(locus name) psi-mi:"h3(112)"(display_short)|psi-mi:EBI-15583943(display_long) psi-mi:"MI:0017"(classical fluorescence spectroscopy) Peña et al. (2006) pubmed:16728977|doi:10.1038/nature04814|imex:IM-21624 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15584190|imex:IM-21624-11|dip:DIP-192055E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_014707.1|sgd:S000005590|dip:DIP-3833N|mint:Q08465|ensemblfungi:YOR064C(gene)|ensemblfungi:YOR064C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0016573"(histone acetylation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033100"(NuA3 histone acetyltransferase complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR028651|rcsb pdb:2JMI|rcsb pdb:2JMJ|reactome:R-SCE-3214847|reactome:R-SCE-3899300|reactome:R-SCE-6804758|reactome:R-SCE-6811555 - psi-mi:"MI:0465"(dip) crc64:5232A71839E2FDA4 - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:L64KyCDWj+yyfGvNsGArHzosRo4559292 rogid:XdPXokAWMXHJQ8/ezeO10lxv77g-2 rigid:ULO3ulkPZ8pXxYjyFFXCGwlkN3k false sufficient binding region:155-204 N6,N6,N6-trimethyl-L-lysine:4-4 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)