#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P08638 uniprotkb:P08638 intact:EBI-10139|uniprotkb:D6VZ85|ensemblfungi:YLR451W intact:EBI-10139|uniprotkb:D6VZ85|ensemblfungi:YLR451W psi-mi:leur_yeast(display_long)|uniprotkb:L9324.1(orf name)|uniprotkb:YLR451W(locus name)|uniprotkb:LEU3(gene name)|psi-mi:LEU3(display_short) psi-mi:leur_yeast(display_long)|uniprotkb:L9324.1(orf name)|uniprotkb:YLR451W(locus name)|uniprotkb:LEU3(gene name)|psi-mi:LEU3(display_short) psi-mi:"MI:0114"(x-ray crystallography) Fitzgerald et al. (2006) pubmed:16615914|doi:10.1016/j.str.2005.11.025|imex:IM-8417 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15579285|imex:IM-8417-1|dip:DIP-2872E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000004443|ensemblfungi:YLR451W(gene)|ensemblfungi:YLR451W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2001278"(positive regulation of leucine biosynthetic process)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:2ER8|rcsb pdb:2ERE|rcsb pdb:2ERG|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_013556.3|dip:DIP-2400N sgd:S000004443|ensemblfungi:YLR451W(gene)|ensemblfungi:YLR451W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009082"(branched-chain amino acid biosynthetic process)|go:"GO:0009098"(leucine biosynthetic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:2001278"(positive regulation of leucine biosynthetic process)|interpro:IPR001138(Fungal transcriptional regulatory protein, N-terminal)|interpro:IPR036864|rcsb pdb:2ER8|rcsb pdb:2ERE|rcsb pdb:2ERG|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|refseq:NP_013556.3|dip:DIP-2400N psi-mi:"MI:0465"(dip) crc64:C5F8EDCD326B1EBB crc64:C5F8EDCD326B1EBB full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:SW0EPUPpYXn9Ad4nww1gevz8GDI559292 rogid:SW0EPUPpYXn9Ad4nww1gevz8GDI559292 rigid:iLxgVjn5O2RLdX/hlZ2BqSqe694 false sufficient binding region:32-103 sufficient binding region:32-103 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)