#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32660 uniprotkb:P42838 intact:EBI-3121|uniprotkb:D3DM74|ensemblfungi:YER166W intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W psi-mi:atc5_yeast(display_long)|uniprotkb:DNF1(gene name)|psi-mi:DNF1(display_short)|uniprotkb:YER166W(locus name)|uniprotkb:SYGP-ORF7(orf name)|uniprotkb:Flippase DNF1(gene name synonym) psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Noji et al. (2006) pubmed:16600184|imex:IM-25645 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643402|imex:IM-25645-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000968|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0090555"(phosphatidylethanolamine flippase activity)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140345"(phosphatidylcholine flippase activity)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY6|rcsb pdb:7KYB|rcsb pdb:7KYC|refseq:NP_011093.3|dip:DIP-7949N|mint:P32660|ensemblfungi:YER166W(gene)|ensemblfungi:YER166W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695 - crc64:3CC3FBA8ADDE8960 crc64:55BDA1F32251B4E6 figure legend:Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/02/08 2017/02/08 rogid:4ciEaV0aGjDqtpexkFJ0l737SpA559292 rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292 rigid:K113XbAj8d/ppcLMEzF12rkjy14 false myc tag:c-c mutation with no effect:316-316 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12675 uniprotkb:P42838 intact:EBI-3114|uniprotkb:D6VS80|ensemblfungi:YDR093W intact:EBI-28396|uniprotkb:D6W0M3|ensemblfungi:YNL323W psi-mi:atc4_yeast(display_long)|uniprotkb:DNF2(gene name)|psi-mi:DNF2(display_short)|uniprotkb:YDR093W(locus name)|uniprotkb:YD8557.01(orf name)|uniprotkb:Flippase DNF2(gene name synonym) psi-mi:lem3_yeast(display_long)|uniprotkb:LEM3(gene name)|psi-mi:LEM3(display_short)|uniprotkb:BRE3(gene name synonym)|uniprotkb:Ro-sensitive 3(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 3(gene name synonym)|uniprotkb:ROS3(gene name synonym)|uniprotkb:N0333(orf name)|uniprotkb:YNL323W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Noji et al. (2006) pubmed:16600184|imex:IM-25645 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-13643410|imex:IM-25645-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010378.1|sgd:S000002500|dip:DIP-8055N|mint:Q12675|ensemblfungi:YDR093W(gene)|ensemblfungi:YDR093W_mRNA(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000749"(response to pheromone triggering conjugation with cellular fusion)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0015031"(protein transport)|go:"GO:0015247"(aminophospholipid flippase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0070867"(mating projection tip membrane)|go:"GO:0071944"(cell periphery)|go:"GO:0140326"(ATPase-coupled intramembrane lipid transporter activity)|go:"GO:0140346"(phosphatidylserine flippase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006539(Phospholipid-translocating P-type ATPase, flippase)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR026871|interpro:IPR032630|interpro:IPR032631|interpro:IPR036412|interpro:IPR044492|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA refseq:NP_014076.1|sgd:S000005267|dip:DIP-4598N|mint:P42838|ensemblfungi:YNL323W(gene)|ensemblfungi:YNL323W_mRNA(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044088"(regulation of vacuole organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0140331"(aminophospholipid translocation)|go:"GO:1990531"(phospholipid-translocating ATPase complex)|interpro:IPR005045(Protein of unknown function DUF284, transmembrane eukaryotic)|rcsb pdb:7KY5|rcsb pdb:7KY7|rcsb pdb:7KY8|rcsb pdb:7KY9|rcsb pdb:7KYA|rcsb pdb:7KYB|rcsb pdb:7KYC|reactome:R-SCE-6798695 - - crc64:55BDA1F32251B4E6 figure legend:Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2017/02/08 2017/02/08 rogid:yfYH/L8WpAsxluGHGiYw3loRtRM559292 rogid:YNU4U5F2bWdXZvJYQ9HK0iWX230559292 rigid:9kQ3U7Pz+xjpely9lMrFxAaqfxo false myc tag:c-c mutation with no effect:316-316 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)