#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P39083	uniprotkb:Q12518	intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0096"(pull down)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574563|imex:IM-23453-1|dip:DIP-197524E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:C805411B57553791	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:s5Qvuoq4cJxtF/PdIefyxh/g/QE	false	glutathione s tranferase tag:n-n	his tag:n-n|sufficient binding region:1-151	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39083	uniprotkb:Q12518	intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574605|imex:IM-23453-3|dip:DIP-197524E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:C805411B57553791	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:s5Qvuoq4cJxtF/PdIefyxh/g/QE	false	sufficient binding region:77-1007	sufficient binding region:1-151	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39083	uniprotkb:Q12518	intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574626|imex:IM-23453-4|dip:DIP-197524E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:C805411B57553791	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:s5Qvuoq4cJxtF/PdIefyxh/g/QE	false	-	sufficient binding region:1-151	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32873	uniprotkb:Q12518	intact:EBI-3531|uniprotkb:D6W3Q3|ensemblfungi:YPL115C	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:bem3_yeast(display_long)|uniprotkb:Bud emergence protein 3(gene name synonym)|uniprotkb:BEM3(gene name)|psi-mi:BEM3(display_short)|uniprotkb:YPL115C(locus name)|uniprotkb:LPH12C(orf name)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574731|imex:IM-23453-9|dip:DIP-197528E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015210.1|sgd:S000006036|dip:DIP-2575N|mint:P32873|ensemblfungi:YPL115C(gene)|ensemblfungi:YPL115C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001683(Phox-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|rcsb pdb:6FSF|rcsb pdb:6LP3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:4BF03EAD6EF10283	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:RGfI7PRsGqNU3o7hXTCNxAXYhSM559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:FBKRJLwfzU99cKzJ+OzLDlC7XYw	false	-	sufficient binding region:1-151	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32873	uniprotkb:Q05785	intact:EBI-3531|uniprotkb:D6W3Q3|ensemblfungi:YPL115C	intact:EBI-35928|uniprotkb:D6VYK7|ensemblfungi:YLR206W	psi-mi:bem3_yeast(display_long)|uniprotkb:Bud emergence protein 3(gene name synonym)|uniprotkb:BEM3(gene name)|psi-mi:BEM3(display_short)|uniprotkb:YPL115C(locus name)|uniprotkb:LPH12C(orf name)	psi-mi:ent2_yeast(display_long)|uniprotkb:YLR206W(locus name)|uniprotkb:ENT2(gene name)|psi-mi:ENT2(display_short)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574668|imex:IM-23453-6|dip:DIP-197531E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015210.1|sgd:S000006036|dip:DIP-2575N|mint:P32873|ensemblfungi:YPL115C(gene)|ensemblfungi:YPL115C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001683(Phox-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|rcsb pdb:6FSF|rcsb pdb:6LP3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034	refseq:NP_013307.1|sgd:S000004196|mint:Q05785|dip:DIP-2698N|ensemblfungi:YLR206W(gene)|ensemblfungi:YLR206W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:4GZC|rcsb pdb:4GZD|rcsb pdb:5ON7|rcsb pdb:6ENR|reactome:R-SCE-8856825	psi-mi:"MI:0465"(dip)	crc64:4BF03EAD6EF10283	crc64:CEC1B2D04C0F7D86	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:RGfI7PRsGqNU3o7hXTCNxAXYhSM559292	rogid:o7k85Z9SbqAjFGEc+28iwiR4CxQ559292	rigid:ZZCUp/hoet5RQgvLRBoyESbK+RM	false	-	sufficient binding region:1-149	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P39083	uniprotkb:Q05785	intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W	intact:EBI-35928|uniprotkb:D6VYK7|ensemblfungi:YLR206W	psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name)	psi-mi:ent2_yeast(display_long)|uniprotkb:YLR206W(locus name)|uniprotkb:ENT2(gene name)|psi-mi:ENT2(display_short)	psi-mi:"MI:0096"(pull down)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574687|imex:IM-23453-7|dip:DIP-197530E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083	refseq:NP_013307.1|sgd:S000004196|mint:Q05785|dip:DIP-2698N|ensemblfungi:YLR206W(gene)|ensemblfungi:YLR206W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:4GZC|rcsb pdb:4GZD|rcsb pdb:5ON7|rcsb pdb:6ENR|reactome:R-SCE-8856825	psi-mi:"MI:0465"(dip)	crc64:C805411B57553791	crc64:CEC1B2D04C0F7D86	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292	rogid:o7k85Z9SbqAjFGEc+28iwiR4CxQ559292	rigid:yj9u/byqo+iYHLQDA/yHvJCqHpU	false	glutathione s tranferase tag:n-n	his tag:n-n|sufficient binding region:1-149	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q06407	uniprotkb:Q12518	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574710|imex:IM-23453-8|dip:DIP-197525E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:FA13BA1DF8B35D98	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:W8iEKJvA3P7DTKDdngmnUyb5uEo	false	sufficient binding region:414-835	sufficient binding region:1-151	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P39083	uniprotkb:Q05785	intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W	intact:EBI-35928|uniprotkb:D6VYK7|ensemblfungi:YLR206W	psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name)	psi-mi:ent2_yeast(display_long)|uniprotkb:YLR206W(locus name)|uniprotkb:ENT2(gene name)|psi-mi:ENT2(display_short)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574586|imex:IM-23453-2|dip:DIP-197530E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083	refseq:NP_013307.1|sgd:S000004196|mint:Q05785|dip:DIP-2698N|ensemblfungi:YLR206W(gene)|ensemblfungi:YLR206W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:4GZC|rcsb pdb:4GZD|rcsb pdb:5ON7|rcsb pdb:6ENR|reactome:R-SCE-8856825	psi-mi:"MI:0465"(dip)	crc64:C805411B57553791	crc64:CEC1B2D04C0F7D86	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292	rogid:o7k85Z9SbqAjFGEc+28iwiR4CxQ559292	rigid:yj9u/byqo+iYHLQDA/yHvJCqHpU	false	-	sufficient binding region:1-149	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88339	uniprotkb:P39083	intact:EBI-7066728|intact:MINT-101104	intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W	psi-mi:epn1_rat(display_long)|uniprotkb:Epn1(gene name)|psi-mi:Epn1(display_short)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)	psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name)	psi-mi:"MI:0096"(pull down)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574645|imex:IM-23453-5|dip:DIP-197533E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:O88339|go:"GO:1905445"(positive regulation of clathrin coat assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:1EDU|rcsb pdb:1EYH|rcsb pdb:1H0A|rcsb pdb:1KY6|reactome:R-RNO-182971|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0090148"(membrane fission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|rgd:619772|refseq:NP_476477.1|dip:DIP-40738N	refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083	psi-mi:"MI:0465"(dip)	comment:mint|function:"Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis"	crc64:C805411B57553791	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:HSxImXvS6/UJyI9kGWz36B0oxiM10116	rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292	rigid:Mhwxp6b4Iw7X1zPN7CLblyF3DII	false	his tag:n-n|sufficient binding region:1-168	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q12518	uniprotkb:Q06407	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:"MI:0096"(pull down)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574750|imex:IM-23453-10|dip:DIP-197525E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	psi-mi:"MI:0465"(dip)	crc64:37447FB4A6449256	crc64:FA13BA1DF8B35D98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rigid:W8iEKJvA3P7DTKDdngmnUyb5uEo	false	his tag:n-n|sufficient binding region:1-151	glutathione s tranferase tag:n-n|sufficient binding region:604-786	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q12518	uniprotkb:Q06407	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:"MI:0096"(pull down)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574862|imex:IM-23453-15|dip:DIP-197525E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	psi-mi:"MI:0465"(dip)	crc64:37447FB4A6449256	crc64:FA13BA1DF8B35D98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rigid:W8iEKJvA3P7DTKDdngmnUyb5uEo	false	mutation disrupting interaction strength:100-100|his tag:n-n|sufficient binding region:1-151	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06407	uniprotkb:Q12518	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574836|imex:IM-23453-14|dip:DIP-197525E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:FA13BA1DF8B35D98	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:W8iEKJvA3P7DTKDdngmnUyb5uEo	false	-	mutation disrupting interaction strength:104-104|mutation disrupting interaction strength:104-104,100-100|sufficient binding region:1-151	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P40020	uniprotkb:Q12518	intact:EBI-13431|uniprotkb:D3DLT1|ensemblfungi:YER032W	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:fir1_yeast(display_long)|uniprotkb:FIR1(gene name)|psi-mi:FIR1(display_short)|uniprotkb:PIP1(gene name synonym)|uniprotkb:Polymerase-interacting protein 1(gene name synonym)|uniprotkb:PAP1-interacting protein(gene name synonym)|uniprotkb:YER032W(locus name)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574817|imex:IM-23453-13|dip:DIP-197526E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010949.4|sgd:S000000834|ensemblfungi:YER032W_mRNA(transcript)|ensemblfungi:YER032W(gene)|go:"GO:0005935"(cellular bud neck)|mint:P40020|dip:DIP-844N|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0043631"(RNA polyadenylation)	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:DFD2AB3684EBC1D2	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:R/cHCy1mdjB79Yt2xUprvf+Fzhs559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:aCePG2rmeUl+1rJNyUz299nDByg	false	-	sufficient binding region:1-151	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O88339	uniprotkb:Q06407	intact:EBI-7066728|intact:MINT-101104	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	psi-mi:epn1_rat(display_long)|uniprotkb:Epn1(gene name)|psi-mi:Epn1(display_short)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574798|imex:IM-23453-12|dip:DIP-197532E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:O88339|go:"GO:1905445"(positive regulation of clathrin coat assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:1EDU|rcsb pdb:1EYH|rcsb pdb:1H0A|rcsb pdb:1KY6|reactome:R-RNO-182971|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0090148"(membrane fission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|rgd:619772|refseq:NP_476477.1|dip:DIP-40738N	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	psi-mi:"MI:0465"(dip)	comment:mint|function:"Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis"	crc64:FA13BA1DF8B35D98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:HSxImXvS6/UJyI9kGWz36B0oxiM10116	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rigid:3UhcY8GYr6DZlu1rA9kKpsAk3gA	false	sufficient binding region:1-168	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O88339	uniprotkb:Q06407	intact:EBI-7066728|intact:MINT-101104	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	psi-mi:epn1_rat(display_long)|uniprotkb:Epn1(gene name)|psi-mi:Epn1(display_short)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:"MI:0096"(pull down)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574775|imex:IM-23453-11|dip:DIP-197532E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:O88339|go:"GO:1905445"(positive regulation of clathrin coat assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:1EDU|rcsb pdb:1EYH|rcsb pdb:1H0A|rcsb pdb:1KY6|reactome:R-RNO-182971|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0090148"(membrane fission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|rgd:619772|refseq:NP_476477.1|dip:DIP-40738N	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	psi-mi:"MI:0465"(dip)	comment:mint|function:"Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis"	crc64:FA13BA1DF8B35D98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:HSxImXvS6/UJyI9kGWz36B0oxiM10116	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rigid:3UhcY8GYr6DZlu1rA9kKpsAk3gA	false	his tag:n-n|sufficient binding region:1-168	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q12518	uniprotkb:Q06407	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574930|imex:IM-23453-18|dip:DIP-197525E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	psi-mi:"MI:0465"(dip)	crc64:37447FB4A6449256	crc64:FA13BA1DF8B35D98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rigid:W8iEKJvA3P7DTKDdngmnUyb5uEo	false	sufficient binding region:1-151	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q05785	uniprotkb:Q06407	intact:EBI-35928|uniprotkb:D6VYK7|ensemblfungi:YLR206W	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	psi-mi:ent2_yeast(display_long)|uniprotkb:YLR206W(locus name)|uniprotkb:ENT2(gene name)|psi-mi:ENT2(display_short)	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:"MI:0096"(pull down)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574907|imex:IM-23453-17|dip:DIP-197529E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013307.1|sgd:S000004196|mint:Q05785|dip:DIP-2698N|ensemblfungi:YLR206W(gene)|ensemblfungi:YLR206W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:4GZC|rcsb pdb:4GZD|rcsb pdb:5ON7|rcsb pdb:6ENR|reactome:R-SCE-8856825	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	psi-mi:"MI:0465"(dip)	crc64:CEC1B2D04C0F7D86	crc64:FA13BA1DF8B35D98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:o7k85Z9SbqAjFGEc+28iwiR4CxQ559292	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rigid:yVSwSQ2YdC6yq7RzZCJ1u+eUFj4	false	his tag:n-n|sufficient binding region:1-149	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O88339	uniprotkb:P39083	intact:EBI-7066728|intact:MINT-101104	intact:EBI-15044|uniprotkb:P39934|uniprotkb:D6W2I5|ensemblfungi:YOR127W	psi-mi:epn1_rat(display_long)|uniprotkb:Epn1(gene name)|psi-mi:Epn1(display_short)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)	psi-mi:rga1_yeast(display_long)|uniprotkb:RGA1(gene name)|psi-mi:RGA1(display_short)|uniprotkb:DBM1(gene name synonym)|uniprotkb:THE1(gene name synonym)|uniprotkb:YOR127W(locus name)|uniprotkb:O3290(orf name)|uniprotkb:YOR3290W(orf name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574888|imex:IM-23453-16|dip:DIP-197533E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:O88339|go:"GO:1905445"(positive regulation of clathrin coat assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:1EDU|rcsb pdb:1EYH|rcsb pdb:1H0A|rcsb pdb:1KY6|reactome:R-RNO-182971|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0090148"(membrane fission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|rgd:619772|refseq:NP_476477.1|dip:DIP-40738N	refseq:NP_014770.1|sgd:S000005653|ensemblfungi:YOR127W(gene)|ensemblfungi:YOR127W_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0001403"(invasive growth in response to glucose limitation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005737"(cytoplasm)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007015"(actin filament organization)|go:"GO:0007118"(budding cell apical bud growth)|go:"GO:0007119"(budding cell isotropic bud growth)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0071597"(cellular birth scar)|go:"GO:2000222"(positive regulation of pseudohyphal growth)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|dip:DIP-1559N|mint:P39083	psi-mi:"MI:0465"(dip)	comment:mint|function:"Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis"	crc64:C805411B57553791	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:HSxImXvS6/UJyI9kGWz36B0oxiM10116	rogid:xdYXgZQ0mCidt7tTuMXDCcBQIxc559292	rigid:Mhwxp6b4Iw7X1zPN7CLblyF3DII	false	sufficient binding region:1-168	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P53939	uniprotkb:Q12518	intact:EBI-28760|uniprotkb:D6W1A1|ensemblfungi:YNL078W	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:nis1_yeast(display_long)|uniprotkb:YNL078W(locus name)|uniprotkb:N2337(orf name)|uniprotkb:NIS1(gene name)|psi-mi:NIS1(display_short)|uniprotkb:JIP1(gene name synonym)|uniprotkb:Neck protein interacting with septins protein 1(gene name synonym)|uniprotkb:Jumonji domain-interacting protein 1(gene name synonym)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574949|imex:IM-23453-19|dip:DIP-197527E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000005022|refseq:NP_014321.3|dip:DIP-1980N|mint:P53939|ensemblfungi:YNL078W(gene)|ensemblfungi:YNL078W_mRNA(transcript)|go:"GO:0005621"(cellular bud scar)|go:"GO:0005634"(nucleus)|go:"GO:0005935"(cellular bud neck)|go:"GO:0007120"(axial cellular bud site selection)|go:"GO:0032153"(cell division site)|go:"GO:0032174"(cellular bud neck septin collar)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0140014"(mitotic nuclear division)	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:925C7B6063BCE4F1	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:F2fY9SQ5kwYH8CZA8vGMZzwRiEM559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:u7KkLhVjp/7Azg2DzAVdRdfOUsQ	false	-	sufficient binding region:1-151	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q05785	uniprotkb:Q06407	intact:EBI-35928|uniprotkb:D6VYK7|ensemblfungi:YLR206W	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	psi-mi:ent2_yeast(display_long)|uniprotkb:YLR206W(locus name)|uniprotkb:ENT2(gene name)|psi-mi:ENT2(display_short)	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574968|imex:IM-23453-20|dip:DIP-197529E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013307.1|sgd:S000004196|mint:Q05785|dip:DIP-2698N|ensemblfungi:YLR206W(gene)|ensemblfungi:YLR206W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:4GZC|rcsb pdb:4GZD|rcsb pdb:5ON7|rcsb pdb:6ENR|reactome:R-SCE-8856825	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	psi-mi:"MI:0465"(dip)	crc64:CEC1B2D04C0F7D86	crc64:FA13BA1DF8B35D98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:o7k85Z9SbqAjFGEc+28iwiR4CxQ559292	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rigid:yVSwSQ2YdC6yq7RzZCJ1u+eUFj4	false	sufficient binding region:1-149	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32873	uniprotkb:Q12518	intact:EBI-3531|uniprotkb:D6W3Q3|ensemblfungi:YPL115C	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	psi-mi:bem3_yeast(display_long)|uniprotkb:Bud emergence protein 3(gene name synonym)|uniprotkb:BEM3(gene name)|psi-mi:BEM3(display_short)|uniprotkb:YPL115C(locus name)|uniprotkb:LPH12C(orf name)	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:"MI:0018"(two hybrid)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574987|imex:IM-23453-21|dip:DIP-197528E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015210.1|sgd:S000006036|dip:DIP-2575N|mint:P32873|ensemblfungi:YPL115C(gene)|ensemblfungi:YPL115C_mRNA(transcript)|go:"GO:0000131"(incipient cellular bud site)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031106"(septin ring organization)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043332"(mating projection tip)|go:"GO:0043547"(positive regulation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR001683(Phox-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036871|rcsb pdb:6FSF|rcsb pdb:6LP3|reactome:R-SCE-6798695|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	psi-mi:"MI:0465"(dip)	crc64:4BF03EAD6EF10283	crc64:37447FB4A6449256	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2017/08/04	2017/08/10	rogid:RGfI7PRsGqNU3o7hXTCNxAXYhSM559292	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rigid:FBKRJLwfzU99cKzJ+OzLDlC7XYw	false	sufficient binding region:334-548	sufficient binding region:1-151	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12518	uniprotkb:Q06407	intact:EBI-31494|uniprotkb:D6VRI8|ensemblfungi:YDL161W	intact:EBI-15060|uniprotkb:D6VT11|ensemblfungi:YDR379W	psi-mi:ent1_yeast(display_long)|uniprotkb:ENT1(gene name)|psi-mi:ENT1(display_short)|uniprotkb:YDL161W(locus name)	psi-mi:rga2_yeast(display_long)|uniprotkb:RGA2(gene name)|psi-mi:RGA2(display_short)|uniprotkb:D9481.4(orf name)|uniprotkb:YDR379W(locus name)	psi-mi:"MI:0096"(pull down)	Aguilar et al. (2006)	pubmed:16537494|doi:10.1073/pnas.0510513103|imex:IM-23453	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15575008|imex:IM-23453-22|dip:DIP-197525E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010120.1|sgd:S000002320|dip:DIP-957N|reactome:R-SCE-8856825|ensemblfungi:YDL161W(gene)|ensemblfungi:YDL161W_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005934"(cellular bud tip)|go:"GO:0005935"(cellular bud neck)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043332"(mating projection tip)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:5AHV|rcsb pdb:5LOZ|rcsb pdb:5ONF|rcsb pdb:7B2L	refseq:NP_010667.1|sgd:S000002787|reactome:R-SCE-8980692|reactome:R-SCE-9013148|reactome:R-SCE-9013405|reactome:R-SCE-9013423|reactome:R-SCE-9035034|ensemblfungi:YDR379W(gene)|ensemblfungi:YDR379W_mRNA(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031106"(septin ring organization)|go:"GO:0032177"(cellular bud neck split septin rings)|go:"GO:0042802"(identical protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-SCE-6798695|dip:DIP-2995N|mint:Q06407	psi-mi:"MI:0465"(dip)	crc64:37447FB4A6449256	crc64:FA13BA1DF8B35D98	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:manWodiLHLhphq1mRdgoZztY1vs559292	rogid:0nehE13u+4HaDfljPdHjDjR9znc559292	rigid:W8iEKJvA3P7DTKDdngmnUyb5uEo	false	-	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)