#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9H9A7 uniprotkb:Q13472 intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508 intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80 psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym) psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym) psi-mi:"MI:0096"(pull down) Wu et al. (2006) pubmed:16537486|doi:10.1073/pnas.0508295103|imex:IM-23452 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15574506|imex:IM-23452-1|dip:DIP-82800E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606 rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606 rigid:OrO7i1ob21yV5KS604y56/rhNdk false maltose binding protein tag:n-n 35s radiolabel:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H9A7 uniprotkb:Q13472 intact:EBI-621339|ensembl:ENSP00000317039|ensembl:ENSP00000402433|uniprotkb:Q5SQG8|uniprotkb:Q5SQG9|uniprotkb:Q6P1Q4|uniprotkb:Q6PI89|uniprotkb:Q7Z6L6|uniprotkb:Q05BX1|uniprotkb:Q05CW3|intact:EBI-2555508 intact:EBI-621345|uniprotkb:Q13473|uniprotkb:D3DXC7|uniprotkb:A8KA61|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENSP00000491689|ensembl:ENSP00000492229|uniprotkb:B4DK80 psi-mi:rmi1_human(display_long)|uniprotkb:BLM-associated protein of 75 kDa(gene name synonym)|uniprotkb:FAAP75(gene name synonym)|uniprotkb:RMI1(gene name)|psi-mi:RMI1(display_short)|uniprotkb:C9orf76(gene name synonym) psi-mi:top3a_human(display_long)|uniprotkb:DNA topoisomerase III alpha(gene name synonym)|uniprotkb:TOP3A(gene name)|psi-mi:TOP3A(display_short)|uniprotkb:TOP3(gene name synonym) psi-mi:"MI:0047"(far western blotting) Wu et al. (2006) pubmed:16537486|doi:10.1073/pnas.0508295103|imex:IM-23452 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15574527|imex:IM-23452-2|dip:DIP-82800E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178966(gene)|ensembl:ENST00000325875(transcript)|ensembl:ENST00000445877(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0031422"(RecQ family helicase-topoisomerase III complex)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR032199|interpro:IPR033472|interpro:IPR042470|rcsb pdb:3MXN|rcsb pdb:3NBH|rcsb pdb:3NBI|rcsb pdb:4CGY|rcsb pdb:4CHT|rcsb pdb:4DAY|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|refseq:XP_011517336.1|refseq:NP_079221.2|refseq:XP_005252268.1|refseq:XP_005252270.1|refseq:XP_016870629.1|dip:DIP-33324N refseq:NP_001307688.1|refseq:NP_004609.1|ensembl:ENSP00000321636|ensembl:ENSP00000442336|ensembl:ENST00000580095|ensembl:ENSP00000462790|ensembl:ENSP00000492229|ensembl:ENST00000639065|ensembl:ENSP00000491260|ensembl:ENSP00000491689|ensembl:ENSG00000177302(gene)|ensembl:ENSG00000284238(gene)|ensembl:ENST00000321105(transcript)|ensembl:ENST00000542570(transcript)|ensembl:ENST00000638894(transcript)|ensembl:ENST00000640743(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006265"(DNA topological change)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0051304"(chromosome separation)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR000380(DNA topoisomerase, type IA, core)|dip:DIP-33323N|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR010666(Zinc finger, GRF-type)|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013498(DNA topoisomerase, type IA, zn finger)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:Q13472|rcsb pdb:4CGY|rcsb pdb:4CHT|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:yB9i9QLqh7s19GI2ZG6WJpWXwOo9606 rogid:KakuT1o8J7sXt7JhWLDPTXiS5go9606 rigid:OrO7i1ob21yV5KS604y56/rhNdk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)