#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P21524	uniprotkb:P21524	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Xu et al. (2006)	pubmed:16537480|doi:10.1073/pnas.0600440103|imex:IM-23450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574390|imex:IM-23450-1|dip:DIP-17764E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	psi-mi:"MI:0465"(dip)	crc64:56BE1B077916E419	crc64:56BE1B077916E419	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/04	2017/08/10	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rigid:ttZBX6bStUAFlhWtJ6zd4mQQ6/M	false	-	-	-	0	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P09938	uniprotkb:P21524	intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym)	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Xu et al. (2006)	pubmed:16537480|doi:10.1073/pnas.0600440103|imex:IM-23450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574407|imex:IM-23450-2|dip:DIP-147618E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	psi-mi:"MI:0465"(dip)	crc64:DB98028408292042	crc64:56BE1B077916E419	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rigid:6p/I8W/fhKWtCCe65bVBOT9I/m0	false	sufficient binding region:391-399	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49723	uniprotkb:P21524	intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C	intact:EBI-15234|uniprotkb:D3DLX5|ensemblfungi:YER070W	psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym)	psi-mi:rir1_yeast(display_long)|uniprotkb:RNR1(gene name)|psi-mi:RNR1(display_short)|uniprotkb:RIR1(gene name synonym)|uniprotkb:Ribonucleotide reductase R1 subunit 1(gene name synonym)|uniprotkb:YER070W(locus name)|uniprotkb:CRT7(gene name synonym)|uniprotkb:SDS12(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit 1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Xu et al. (2006)	pubmed:16537480|doi:10.1073/pnas.0600440103|imex:IM-23450	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15574427|imex:IM-23450-3|dip:DIP-197523E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723	refseq:NP_010993.1|sgd:S000000872|rcsb pdb:3S8B|rcsb pdb:3S8C|rcsb pdb:3TB9|rcsb pdb:3TBA|ensemblfungi:YER070W(gene)|ensemblfungi:YER070W_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0042802"(identical protein binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:1ZYZ|rcsb pdb:1ZZD|rcsb pdb:2CVS|rcsb pdb:2CVT|rcsb pdb:2CVU|rcsb pdb:2CVV|rcsb pdb:2CVW|rcsb pdb:2CVX|rcsb pdb:2CVY|rcsb pdb:2EUD|rcsb pdb:2ZLF|rcsb pdb:2ZLG|rcsb pdb:3K8T|rcsb pdb:3PAW|rcsb pdb:3RSR|rcsb pdb:3S87|rcsb pdb:3S8A|dip:DIP-6299N|mint:P21524	psi-mi:"MI:0465"(dip)	crc64:712853F2D87D3972	crc64:56BE1B077916E419	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292	rogid:mJYNF2Ima51+N2HtemtKmdfzZ1k559292	rigid:1mPLWnaABW+wPHbRjsY9Um/50CE	false	sufficient binding region:337-345	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)