#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P21279	uniprotkb:O54912	intact:EBI-771975|uniprotkb:Q6PFF5|ensembl:ENSMUSP00000025541	intact:EBI-15571519|ensembl:ENSRNOP00000013107	psi-mi:gnaq_mouse(display_long)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)|uniprotkb:Gnaq(gene name)|psi-mi:Gnaq(display_short)	psi-mi:kcnk3_rat(display_long)|uniprotkb:Kcnk3(gene name)|psi-mi:Kcnk3(display_short)|uniprotkb:Task(gene name synonym)|uniprotkb:Task1(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-1(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 1"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chen et al. (2006)	pubmed:16492788|doi:10.1073/pnas.0507710103|imex:IM-23443	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15571558|imex:IM-23443-1|dip:DIP-197515E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032165.3|dip:DIP-606N|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P21279|rcsb pdb:2BCJ|rcsb pdb:2RGN|rcsb pdb:3AH8|rcsb pdb:3OHM|rcsb pdb:4EKC|rcsb pdb:4EKD|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|rcsb pdb:5DO9|reactome:R-MMU-112043|reactome:R-MMU-202040|reactome:R-MMU-399997|reactome:R-MMU-416476|reactome:R-MMU-418592|reactome:R-MMU-428930|reactome:R-MMU-434316|reactome:R-MMU-456926|reactome:R-MMU-6814122|go:"GO:0044297"(cell body)|ensembl:ENSMUSG00000024639(gene)|ensembl:ENSMUST00000025541(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016322"(neuron remodeling)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042711"(maternal behavior)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043267"(negative regulation of potassium ion transport)	ensembl:ENSRNOG00000009790(gene)|ensembl:ENSRNOT00000013107(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005252"(open rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0044548"(S100 protein binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005406(Potassium channel, two pore-domain, TASK-1)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299316|reactome:R-RNO-5576886|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|refseq:NP_203694.1|rgd:61997|dip:DIP-61121N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/04	2017/08/10	rogid:7HfYjIynxSexMzn1uUS6x4sfzbI10090	rogid:M338dnV5PQKmJlR1Bt52YGoSirI10116	rigid:Lq6cAtOw0NujV2n20PXpJsx+oY0	false	-	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9ES08	uniprotkb:P21279	intact:EBI-15571577|ensembl:ENSRNOP00000012408|uniprotkb:Q923V6|uniprotkb:Q9JLD4	intact:EBI-771975|uniprotkb:Q6PFF5|ensembl:ENSMUSP00000025541	psi-mi:kcnk9_rat(display_long)|uniprotkb:Kcnk9(gene name)|psi-mi:Kcnk9(display_short)|uniprotkb:Task3(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-3(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 3"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.2(gene name synonym)	psi-mi:gnaq_mouse(display_long)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)|uniprotkb:Gnaq(gene name)|psi-mi:Gnaq(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chen et al. (2006)	pubmed:16492788|doi:10.1073/pnas.0507710103|imex:IM-23443	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15571606|imex:IM-23443-2|dip:DIP-197516E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000009265(gene)|ensembl:ENSRNOT00000012408(transcript)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005407(Potassium channel, two pore-domain, TASK-3)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299316|reactome:R-RNO-5576886|refseq:NP_445857.2|refseq:XP_017450625.1|rgd:621451|dip:DIP-61122N	refseq:NP_032165.3|dip:DIP-606N|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P21279|rcsb pdb:2BCJ|rcsb pdb:2RGN|rcsb pdb:3AH8|rcsb pdb:3OHM|rcsb pdb:4EKC|rcsb pdb:4EKD|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|rcsb pdb:5DO9|reactome:R-MMU-112043|reactome:R-MMU-202040|reactome:R-MMU-399997|reactome:R-MMU-416476|reactome:R-MMU-418592|reactome:R-MMU-428930|reactome:R-MMU-434316|reactome:R-MMU-456926|reactome:R-MMU-6814122|go:"GO:0044297"(cell body)|ensembl:ENSMUSG00000024639(gene)|ensembl:ENSMUST00000025541(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016322"(neuron remodeling)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042711"(maternal behavior)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043267"(negative regulation of potassium ion transport)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/04	2017/08/10	rogid:FDeYIT6gevyPjCxdPGOOlfI5SgQ10116	rogid:7HfYjIynxSexMzn1uUS6x4sfzbI10090	rigid:LV8zx+nRExPSJo5IRh5UXqHUpyg	false	ha tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P21278	uniprotkb:O54912	intact:EBI-15571625|ensembl:ENSMUSP00000043190|uniprotkb:Q61939	intact:EBI-15571519|ensembl:ENSRNOP00000013107	psi-mi:gna11_mouse(display_long)|uniprotkb:Gna11(gene name)|psi-mi:Gna11(display_short)|uniprotkb:Gna-11(gene name synonym)	psi-mi:kcnk3_rat(display_long)|uniprotkb:Kcnk3(gene name)|psi-mi:Kcnk3(display_short)|uniprotkb:Task(gene name synonym)|uniprotkb:Task1(gene name synonym)|uniprotkb:Acid-sensitive potassium channel protein TASK-1(gene name synonym)|uniprotkb:"TWIK-related acid-sensitive K(+) channel 1"(gene name synonym)|uniprotkb:Two pore potassium channel KT3.1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chen et al. (2006)	pubmed:16492788|doi:10.1073/pnas.0507710103|imex:IM-23443	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15571669|imex:IM-23443-3|dip:DIP-197517E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000034781(gene)|ensembl:ENSMUST00000043604(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0071467"(cellular response to pH)|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|reactome:R-MMU-112043|reactome:R-MMU-202040|reactome:R-MMU-399997|reactome:R-MMU-416476|reactome:R-MMU-418592|reactome:R-MMU-428930|reactome:R-MMU-434316|reactome:R-MMU-456926|reactome:R-MMU-6814122|refseq:NP_034431.1|dip:DIP-603N	ensembl:ENSRNOG00000009790(gene)|ensembl:ENSRNOT00000013107(transcript)|go:"GO:0005216"(ion channel activity)|go:"GO:0005252"(open rectifier potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022841"(potassium ion leak channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0042493"|go:"GO:0044548"(S100 protein binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0090102"(cochlea development)|interpro:IPR003280(Potassium channel, two pore-domain)|interpro:IPR005406(Potassium channel, two pore-domain, TASK-1)|interpro:IPR013099(Ion transport 2)|reactome:R-RNO-1299316|reactome:R-RNO-5576886|interpro:IPR003092(Potassium channel, two pore-domain, TASK)|refseq:NP_203694.1|rgd:61997|dip:DIP-61121N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/04	2017/08/10	rogid:HzMrR557jIl9sHKzMotEP37fuFI10090	rogid:M338dnV5PQKmJlR1Bt52YGoSirI10116	rigid:4GzHTvhBc2uQGcQv6yGVaZTPQx0	false	-	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)