#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O75695 uniprotkb:Q9WUL7 intact:EBI-7996807|uniprotkb:Q9NU67|uniprotkb:Q86XJ7|intact:MINT-5003911|ensembl:ENSP00000218340 intact:EBI-6860857|ensembl:ENSMUSP00000026009 psi-mi:xrp2_human(display_long)|uniprotkb:RP2(gene name)|psi-mi:RP2(display_short) psi-mi:arl3_mouse(display_long)|uniprotkb:Arl3(gene name)|psi-mi:Arl3(display_short) psi-mi:"MI:0053"(fluorescence polarization spectroscopy) Kühnel et al. (2006) doi:10.1016/j.str.2005.11.008|imex:IM-8311|pubmed:16472755 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568441|imex:IM-8311-1|dip:DIP-57025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008846.2|dip:DIP-29024N|ensembl:ENSG00000102218(gene)|ensembl:ENST00000218340(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007601"(visual perception)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990075"(periciliary membrane compartment)|interpro:IPR006599(CARP motif)|interpro:IPR012945(Tubulin binding cofactor C)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR036223|interpro:IPR036850|interpro:IPR039093|mint:O75695|rcsb pdb:2BX6|rcsb pdb:3BH6|rcsb pdb:3BH7|reactome:R-HSA-5624138 go:"GO:1903441"(protein localization to ciliary membrane)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:Q9WUL7|rcsb pdb:1FZQ|rcsb pdb:3BH6|rcsb pdb:3BH7|rcsb pdb:4GOJ|rcsb pdb:4ZI2|rcsb pdb:4ZI3|rcsb pdb:7OK7|reactome:R-MMU-5624138|ensembl:ENSMUSG00000025035(gene)|ensembl:ENSMUST00000026009(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001822"(kidney development)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0015031"(protein transport)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|refseq:NP_062692.1|dip:DIP-29025N psi-mi:"MI:0465"(dip) comment:mint|function:Stimulates the GTPase activity of tubulin, but does not enhance tubulin heterodimerization. Acts as guanine nucleotide dissociation inhibitor for ARL3|function:"Defects in RP2 are the cause of retinitis pigmentosa type 2 (RP2) [MIM:312600]; also known as X-linked retinitis pigmentosa 2 (XLRP-2). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well" - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:34VzWqa5cV0XAIxDOCDGzd+1VPk9606 rogid:Pv4G4Y6wahs2lvrFtlxPhmF23ew10090 rigid:nqPDZpQEaEBoZSrzLOWUp+wR69g false sufficient binding region:1-230 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)