#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P9WGK7 uniprotkb:P9WGK7 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:"MI:0114"(x-ray crystallography) Nowak et al. (2006) pubmed:16472747|doi:10.1016/j.str.2005.10.006|imex:IM-8334 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568102|imex:IM-8334-6|dip:DIP-57034E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N psi-mi:"MI:0465"(dip) crc64:CD84A335CCFFE6D7 crc64:CD84A335CCFFE6D7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rigid:xX0xSFTuela6ZeJHq3sEw1t+aac false sufficient binding region:174-446 sufficient binding region:174-446 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WGK7 uniprotkb:P9WGK7 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:"MI:0071"(molecular sieving) Nowak et al. (2006) pubmed:16472747|doi:10.1016/j.str.2005.10.006|imex:IM-8334 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568086|imex:IM-8334-2|dip:DIP-57034E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N psi-mi:"MI:0465"(dip) crc64:CD84A335CCFFE6D7 crc64:CD84A335CCFFE6D7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rigid:xX0xSFTuela6ZeJHq3sEw1t+aac false - - - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WGK7 uniprotkb:P9WGK7 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:"MI:0114"(x-ray crystallography) Nowak et al. (2006) pubmed:16472747|doi:10.1016/j.str.2005.10.006|imex:IM-8334 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568120|imex:IM-8334-4|dip:DIP-57034E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N psi-mi:"MI:0465"(dip) crc64:CD84A335CCFFE6D7 crc64:CD84A335CCFFE6D7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rigid:xX0xSFTuela6ZeJHq3sEw1t+aac false sufficient binding region:223-446 sufficient binding region:223-446 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WGK7 uniprotkb:P9WGK7 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:"MI:0071"(molecular sieving) Nowak et al. (2006) pubmed:16472747|doi:10.1016/j.str.2005.10.006|imex:IM-8334 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568138|imex:IM-8334-8|dip:DIP-57034E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N psi-mi:"MI:0465"(dip) crc64:CD84A335CCFFE6D7 crc64:CD84A335CCFFE6D7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rigid:xX0xSFTuela6ZeJHq3sEw1t+aac false sufficient binding region:174-446 sufficient binding region:174-446 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WGK7 uniprotkb:P9WGK7 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:"MI:0071"(molecular sieving) Nowak et al. (2006) pubmed:16472747|doi:10.1016/j.str.2005.10.006|imex:IM-8334 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568156|imex:IM-8334-3|dip:DIP-57034E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N psi-mi:"MI:0465"(dip) crc64:CD84A335CCFFE6D7 crc64:CD84A335CCFFE6D7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rigid:xX0xSFTuela6ZeJHq3sEw1t+aac false sufficient binding region:223-446 sufficient binding region:223-446 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WGM1 uniprotkb:P9WGK7 intact:EBI-15568192|uniprotkb:L0T590|uniprotkb:P0A5Z6|uniprotkb:Q10531 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 psi-mi:prra_myctu(display_long)|uniprotkb:prrA(gene name)|psi-mi:prrA(display_short)|uniprotkb:MTCY31.31c(orf name)|uniprotkb:Rv0903c(locus name) psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:"MI:0415"(enzymatic study) Nowak et al. (2006) pubmed:16472747|doi:10.1016/j.str.2005.10.006|imex:IM-8334 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568220|imex:IM-8334-7|dip:DIP-57035E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR011006(CheY-like)|interpro:IPR036388|interpro:IPR039420|rcsb pdb:1YS6|rcsb pdb:1YS7|refseq:NP_215418.1|dip:DIP-29035N go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N psi-mi:"MI:0465"(dip) caution:This sequence has been withdrawn from Uniprot.|crc64:B8B38C20BF917082 crc64:CD84A335CCFFE6D7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:P+0Ex8VyfKO0bXMueRTIVqRdkLY83332 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rigid:8CvUbH5hY24HUf5p/A9kraqC1uw false - sufficient binding region:174-446 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WGK7 uniprotkb:P9WGK7 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:"MI:0114"(x-ray crystallography) Nowak et al. (2006) pubmed:16472747|doi:10.1016/j.str.2005.10.006|imex:IM-8334 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568174|imex:IM-8334-5|dip:DIP-57034E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N psi-mi:"MI:0465"(dip) crc64:CD84A335CCFFE6D7 crc64:CD84A335CCFFE6D7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rigid:xX0xSFTuela6ZeJHq3sEw1t+aac false sufficient binding region:297-446 sufficient binding region:297-446 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WGK7 uniprotkb:P9WGK7 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 intact:EBI-15568059|uniprotkb:L0T543|uniprotkb:P0A5Z8|uniprotkb:Q10560 psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:prrb_myctu(display_long)|uniprotkb:prrB(gene name)|psi-mi:prrB(display_short)|uniprotkb:MTCY31.30c(orf name)|uniprotkb:Rv0902c(locus name) psi-mi:"MI:0071"(molecular sieving) Nowak et al. (2006) pubmed:16472747|doi:10.1016/j.str.2005.10.006|imex:IM-8334 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568239|imex:IM-8334-1|dip:DIP-57034E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR003660(Signal transduction histidine kinase, HAMP region)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR036097|interpro:IPR036890|rcsb pdb:1YS3|rcsb pdb:1YSR|refseq:NP_215417.1|refseq:WP_003404689.1|dip:DIP-29034N psi-mi:"MI:0465"(dip) crc64:CD84A335CCFFE6D7 crc64:CD84A335CCFFE6D7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rogid:5n+Anu3FKSGJsctje7w1vwzggGg83332 rigid:xX0xSFTuela6ZeJHq3sEw1t+aac false sufficient binding region:297-446 sufficient binding region:297-446 - 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)