#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O08808 uniprotkb:O08808 intact:EBI-1026445|ensembl:ENSMUSP00000111297 intact:EBI-1026445|ensembl:ENSMUSP00000111297 psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nezami et al. (2006) pubmed:16472745|doi:10.1016/j.str.2005.12.003|imex:IM-8336 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15567944|imex:IM-8336-3|dip:DIP-57028E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rigid:njCYvO+5Zem6E7or+XhD1MwFKmY false sufficient binding region:736-1200 sufficient binding region:72-369 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08808 uniprotkb:O08808 intact:EBI-1026445|ensembl:ENSMUSP00000111297 intact:EBI-1026445|ensembl:ENSMUSP00000111297 psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Nezami et al. (2006) pubmed:16472745|doi:10.1016/j.str.2005.12.003|imex:IM-8336 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15567986|imex:IM-8336-4|dip:DIP-57028E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rigid:njCYvO+5Zem6E7or+XhD1MwFKmY false sufficient binding region:1175-1200 sufficient binding region:131-369 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08808 uniprotkb:O08808 intact:EBI-1026445|ensembl:ENSMUSP00000111297 intact:EBI-1026445|ensembl:ENSMUSP00000111297 psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nezami et al. (2006) pubmed:16472745|doi:10.1016/j.str.2005.12.003|imex:IM-8336 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568007|imex:IM-8336-5|dip:DIP-57028E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rigid:njCYvO+5Zem6E7or+XhD1MwFKmY false sufficient binding region:1175-1200 sufficient binding region:131-369 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08808 uniprotkb:O08808 intact:EBI-1026445|ensembl:ENSMUSP00000111297 intact:EBI-1026445|ensembl:ENSMUSP00000111297 psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nezami et al. (2006) pubmed:16472745|doi:10.1016/j.str.2005.12.003|imex:IM-8336 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15567965|imex:IM-8336-1|dip:DIP-57028E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rigid:njCYvO+5Zem6E7or+XhD1MwFKmY false sufficient binding region:736-1200 sufficient binding region:131-369 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O08808 uniprotkb:O08808 intact:EBI-1026445|ensembl:ENSMUSP00000111297 intact:EBI-1026445|ensembl:ENSMUSP00000111297 psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:diap1_mouse(display_long)|uniprotkb:Diaphanous-related formin-1(gene name synonym)|uniprotkb:p140mDIA(gene name synonym)|uniprotkb:Diaph1(gene name)|psi-mi:Diaph1(display_short)|uniprotkb:Diap1(gene name synonym) psi-mi:"MI:0065"(isothermal titration calorimetry) Nezami et al. (2006) pubmed:16472745|doi:10.1016/j.str.2005.12.003|imex:IM-8336 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15568028|imex:IM-8336-2|dip:DIP-57028E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N refseq:NP_031884.1|ensembl:ENSMUSG00000024456(gene)|ensembl:ENSMUST00000115634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007420"(brain development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051279"(regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0071420"(cellular response to histamine)|go:"GO:0072686"(mitotic spindle)|interpro:IPR010465(DRF autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027653|interpro:IPR042201|mint:O08808|rcsb pdb:1Z2C|rcsb pdb:2BAP|rcsb pdb:2BNX|rcsb pdb:2F31|rcsb pdb:2V8F|rcsb pdb:3EG5|rcsb pdb:3O4X|rcsb pdb:3OBV|rcsb pdb:4UWX|reactome:R-MMU-5663220|reactome:R-MMU-6785631|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013405|reactome:R-MMU-9035034|rcsb pdb:1V9D|dip:DIP-29028N psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rogid:cSWfzfilw9WnzAOYZE3i+0x9G5c10090 rigid:njCYvO+5Zem6E7or+XhD1MwFKmY false sufficient binding region:1175-1200 sufficient binding region:72-369 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)