#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O14964	uniprotkb:P62990	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Hirano et al. (2006)	pubmed:16462748|doi:10.1038/nsmb1051|imex:IM-8357	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567333|imex:IM-8357-2|dip:DIP-57054E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/15	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:j1mp5Gu0QFii+5S3LPs0IXNG2Po	false	sufficient binding region:257-277	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14964	uniprotkb:P62990	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Hirano et al. (2006)	pubmed:16462748|doi:10.1038/nsmb1051|imex:IM-8357	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567352|imex:IM-8357-3|dip:DIP-57054E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/15	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:j1mp5Gu0QFii+5S3LPs0IXNG2Po	false	sufficient binding region:251-286|mutation disrupting interaction:268-268,266-266|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P25686	uniprotkb:P62990	intact:EBI-6166532|ensembl:ENSP00000338019|uniprotkb:A8K9P6|uniprotkb:Q8IUK1|uniprotkb:Q8IUK2|uniprotkb:Q96F52|uniprotkb:Q53QD7	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:dnjb2_human(display_long)|uniprotkb:DNAJB2(gene name)|psi-mi:DNAJB2(display_short)|uniprotkb:HSJ1(gene name synonym)|uniprotkb:HSPF3(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 3(gene name synonym)|uniprotkb:Heat shock protein J1(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Hirano et al. (2006)	pubmed:16462748|doi:10.1038/nsmb1051|imex:IM-8357	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567377|imex:IM-8357-1|dip:DIP-57055E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000135924(gene)|ensembl:ENST00000336576(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016234"(inclusion body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070628"(proteasome binding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0090086"(negative regulation of protein deubiquitination)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903644"(regulation of chaperone-mediated protein folding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR018253|interpro:IPR036869|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042026"(protein refolding)|go:"GO:0042406"(extrinsic component of endoplasmic reticulum membrane)|go:"GO:0043130"(ubiquitin binding)|mint:P25686|rcsb pdb:2LGW|interpro:IPR043183|refseq:NP_001034639.1|refseq:NP_006727.2|dip:DIP-29051N	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/15	rogid:BpmS2Mrk3FLzXLC0o3vIvSVPd3c9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:VAgrfzs5woxnRCITdfBHdK0BlY0	false	sufficient binding region:245-272|mutation decreasing interaction:260-260,258-258|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P42567	uniprotkb:P62990	intact:EBI-443923|ensembl:ENSMUSP00000099790|uniprotkb:Q8C431	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:eps15_mouse(display_long)|uniprotkb:Protein AF-1p(gene name synonym)|uniprotkb:Eps15(gene name)|psi-mi:Eps15(display_short)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Hirano et al. (2006)	pubmed:16462748|doi:10.1038/nsmb1051|imex:IM-8357	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567402|imex:IM-8357-4|dip:DIP-57056E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUST00000102729(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|ensembl:ENSMUSG00000028552(gene)|go:"GO:0060170"(ciliary membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42567|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QJT|reactome:R-MMU-182971|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_001153436.1|refseq:NP_031969.1|dip:DIP-29052N	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/15	rogid:VmZn/g1//dOm/lWdGU55mTQBOjI10090	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:YIExUuhs2dPxC+fT943vsggAA64	false	sufficient binding region:867-897|mutation decreasing interaction:888-888,886-886|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)