#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O18973	uniprotkb:P62990	intact:EBI-447376	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:rabx5_bovin(display_long)|uniprotkb:Rabex-5(gene name synonym)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)|uniprotkb:RABEX5(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0114"(x-ray crystallography)	Lee et al. (2006)	pubmed:16462746|doi:10.1038/nsmb1064|imex:IM-8363	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567137|imex:IM-8363-1|dip:DIP-57060E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_777016.1|dip:DIP-29059N|go:"GO:0003677"(DNA binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|rcsb pdb:2FID|rcsb pdb:2FIF	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/15	rogid:NtEzuCiWGNRP45zpcQEhzWj3kuI9913	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:6L1BrteGyV9dPJYniUYeGZEY+ms	false	sufficient binding region:9-73	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O18973	uniprotkb:P62990	intact:EBI-447376	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:rabx5_bovin(display_long)|uniprotkb:Rabex-5(gene name synonym)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)|uniprotkb:RABEX5(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Lee et al. (2006)	pubmed:16462746|doi:10.1038/nsmb1064|imex:IM-8363	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567156|imex:IM-8363-3|dip:DIP-57060E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_777016.1|dip:DIP-29059N|go:"GO:0003677"(DNA binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|rcsb pdb:2FID|rcsb pdb:2FIF	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/15	rogid:NtEzuCiWGNRP45zpcQEhzWj3kuI9913	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:6L1BrteGyV9dPJYniUYeGZEY+ms	false	sufficient binding region:9-73|mutation decreasing interaction:26-26|mutation decreasing interaction:58-58|mutation disrupting interaction:58-58,25-25	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P61077-1	uniprotkb:O18973	intact:EBI-15567256|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|ensembl:ENSP00000378283|ensembl:ENSP00000396901	intact:EBI-447376	psi-mi:p61077-1(display_long)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)	psi-mi:rabx5_bovin(display_long)|uniprotkb:Rabex-5(gene name synonym)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)|uniprotkb:RABEX5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2006)	pubmed:16462746|doi:10.1038/nsmb1064|imex:IM-8363	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567272|imex:IM-8363-6|dip:DIP-57062E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|ensembl:ENSG00000109332(gene)|intact:EBI-348268(isoform-parent)	refseq:NP_777016.1|dip:DIP-29059N|go:"GO:0003677"(DNA binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|rcsb pdb:2FID|rcsb pdb:2FIF	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rogid:NtEzuCiWGNRP45zpcQEhzWj3kuI9913	rigid:XVDx3KEc294+U4N3bosVH+iYRlU	false	-	sufficient binding region:9-73|mutation disrupting interaction:26-26,25-25|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P60605	uniprotkb:Q9UKV5	intact:EBI-9108745|uniprotkb:P56554|ensembl:ENSMUSP00000133515	intact:EBI-1046367|ensembl:ENSP00000290649|uniprotkb:Q8IZ70|intact:EBI-2340887|uniprotkb:P26442|intact:EBI-1046379	psi-mi:ub2g2_mouse(display_long)|uniprotkb:Ube2g2(gene name)|psi-mi:Ube2g2(display_short)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubc7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)	psi-mi:amfr_human(display_long)|uniprotkb:gp78(gene name synonym)|uniprotkb:RING finger protein 45(gene name synonym)|uniprotkb:AMFR(gene name)|psi-mi:AMFR(display_short)|uniprotkb:RNF45(gene name synonym)|uniprotkb:Autocrine motility factor receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2006)	pubmed:16462746|doi:10.1038/nsmb1064|imex:IM-8363	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567235|imex:IM-8363-5|dip:DIP-57061E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_062777.2|dip:DIP-29061N|ensembl:ENSMUSG00000009293(gene)|ensembl:ENSMUST00000174510(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:3FSH|reactome:R-MMU-8866652|reactome:R-MMU-983168|go:"GO:0000209"(protein polyubiquitination)	ensembl:ENSG00000159461(gene)|ensembl:ENST00000290649(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904288"(BAT3 complex binding)|rcsb pdb:3FSH|go:"GO:1904380"(endoplasmic reticulum mannose trimming)|rcsb pdb:3H8K|rcsb pdb:3TIW|rcsb pdb:4G3O|rcsb pdb:4LAD|reactome:R-HSA-532668|reactome:R-HSA-901032|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:2000638"(regulation of SREBP signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR040675|mint:Q9UKV5|rcsb pdb:2EJS|rcsb pdb:2LVN|rcsb pdb:2LVO|rcsb pdb:2LVP|rcsb pdb:2LVQ|rcsb pdb:2LXH|rcsb pdb:2LXP|refseq:NP_001135.3|refseq:NP_001310441.1|dip:DIP-29060N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI10090	rogid:D24ZWFiUJvfOruzRxjn2p45ZFd09606	rigid:Lxp/CWtZVUK+SqJnVm3bBNfIGI0	false	-	sufficient binding region:574-643|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O18973	uniprotkb:P62990	intact:EBI-447376	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:rabx5_bovin(display_long)|uniprotkb:Rabex-5(gene name synonym)|uniprotkb:RABGEF1(gene name)|psi-mi:RABGEF1(display_short)|uniprotkb:RABEX5(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Lee et al. (2006)	pubmed:16462746|doi:10.1038/nsmb1064|imex:IM-8363	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567185|imex:IM-8363-4|dip:DIP-57060E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_777016.1|dip:DIP-29059N|go:"GO:0003677"(DNA binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015031"(protein transport)|go:"GO:0055037"(recycling endosome)|interpro:IPR002653(Zinc finger, A20-type)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR037191|interpro:IPR041545|rcsb pdb:2FID|rcsb pdb:2FIF	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/15	rogid:NtEzuCiWGNRP45zpcQEhzWj3kuI9913	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:6L1BrteGyV9dPJYniUYeGZEY+ms	false	mutation disrupting interaction:26-26|sufficient binding region:9-73|mutation disrupting interaction:25-25|mutation disrupting interaction:26-26|mutation disrupting interaction:51-51|mutation disrupting interaction:57-57|mutation disrupting interaction:58-58|mutation disrupting interaction:57-57,25-25|mutation disrupting interaction:58-58,25-25|mutation disrupting interaction:57-57,26-26|mutation disrupting interaction:25-25	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96BH1	uniprotkb:P61077-1	intact:EBI-2129220|uniprotkb:A8K0D6|uniprotkb:Q9H874|uniprotkb:Q53HQ5|ensembl:ENSP00000295704	intact:EBI-15567256|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|ensembl:ENSP00000378283|ensembl:ENSP00000396901	psi-mi:rnf25_human(display_long)|uniprotkb:RNF25(gene name)|psi-mi:RNF25(display_short)|uniprotkb:RING finger protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF25(gene name synonym)	psi-mi:p61077-1(display_long)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Lee et al. (2006)	pubmed:16462746|doi:10.1038/nsmb1064|imex:IM-8363	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15567297|imex:IM-8363-2|dip:DIP-57063E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_071898.2|dip:DIP-29063N|ensembl:ENSG00000163481(gene)|ensembl:ENST00000295704(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR006575(RWD)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR039133|rcsb pdb:2DAY|rcsb pdb:2DMF|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|reactome:R-HSA-983168	ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|ensembl:ENSG00000109332(gene)|intact:EBI-348268(isoform-parent)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:YyCN7mH4eng9G05zRci49oJzKO09606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rigid:8lTGkXyjoGK73qPlh3cIjtFLnB8	false	sufficient binding region:86-363|glutathione s tranferase tag:n-n	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)