#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P09938 uniprotkb:P49723 intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16432237|doi:10.1073/pnas.0510516103|imex:IM-23401 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15565905|imex:IM-23401-1|dip:DIP-197441E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723 psi-mi:"MI:0465"(dip) crc64:DB98028408292042 crc64:712853F2D87D3972 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292 rigid:QGbgo0cpLcS/Ffb5uHRMu0fA8/E false flag tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P09938 uniprotkb:Q12363 intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W intact:EBI-20563|uniprotkb:O00041|uniprotkb:D6W2T4|ensemblfungi:YOR230W psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:wtm1_yeast(display_long)|uniprotkb:WTM1(gene name)|psi-mi:WTM1(display_short)|uniprotkb:YOR50-20(orf name)|uniprotkb:YOR230W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16432237|doi:10.1073/pnas.0510516103|imex:IM-23401 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15565905|imex:IM-23401-1|dip:DIP-197441E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 refseq:NP_014873.3|sgd:S000005756|ensemblfungi:YOR230W(gene)|ensemblfungi:YOR230W_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-4558N|mint:Q12363 psi-mi:"MI:0465"(dip) crc64:DB98028408292042 crc64:C3E3822DABB53AEC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 rogid:CwDzANIN+3kwYw1ikCUNqyWHD6s559292 rigid:QGbgo0cpLcS/Ffb5uHRMu0fA8/E false flag tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P09938 uniprotkb:Q12206 intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W intact:EBI-20571|uniprotkb:D6W2T3|ensemblfungi:YOR229W psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:wtm2_yeast(display_long)|uniprotkb:WTM2(gene name)|psi-mi:WTM2(display_short)|uniprotkb:YOR50-19(orf name)|uniprotkb:YOR229W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16432237|doi:10.1073/pnas.0510516103|imex:IM-23401 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15565905|imex:IM-23401-1|dip:DIP-197441E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 refseq:NP_014872.1|sgd:S000005755|ensemblfungi:YOR229W(gene)|ensemblfungi:YOR229W_mRNA(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0034629"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-1534N|mint:Q12206 psi-mi:"MI:0465"(dip) crc64:DB98028408292042 crc64:4A8F5F879B88AA94 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 rogid:DCudPHib/PxB5+S+RRONJQyC+QI559292 rigid:QGbgo0cpLcS/Ffb5uHRMu0fA8/E false flag tag:c-c - - - psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry) uniprotkb:P32767 uniprotkb:Q12363 intact:EBI-13044|uniprotkb:D6VUC1|ensemblfungi:YGL016W intact:EBI-20563|uniprotkb:O00041|uniprotkb:D6W2T4|ensemblfungi:YOR230W psi-mi:ka122_yeast(display_long)|uniprotkb:KAP122(gene name)|psi-mi:KAP122(display_short)|uniprotkb:PDR6(gene name synonym)|uniprotkb:Karyopherin-122(gene name synonym)|uniprotkb:Pleiotropic drug resistance regulatory protein 6(gene name synonym)|uniprotkb:YGL016W(locus name) psi-mi:wtm1_yeast(display_long)|uniprotkb:WTM1(gene name)|psi-mi:WTM1(display_short)|uniprotkb:YOR50-20(orf name)|uniprotkb:YOR230W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16432237|doi:10.1073/pnas.0510516103|imex:IM-23401 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15565947|imex:IM-23401-3|dip:DIP-197440E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011499.1|sgd:S000002984|mint:P32767|dip:DIP-2449N|ensemblfungi:YGL016W(gene)|ensemblfungi:YGL016W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008361"(regulation of cell size)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6Q82|rcsb pdb:6Q83|rcsb pdb:6Q84 refseq:NP_014873.3|sgd:S000005756|ensemblfungi:YOR230W(gene)|ensemblfungi:YOR230W_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-4558N|mint:Q12363 psi-mi:"MI:0465"(dip) crc64:EEBC5ADD4E16D9D3 crc64:C3E3822DABB53AEC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:azK0CUm6ZvPpkaHa6uwppETz9iI559292 rogid:CwDzANIN+3kwYw1ikCUNqyWHD6s559292 rigid:1RADNW0r7tuC0du03C9c7FFsX9c false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32767 uniprotkb:Q12363 intact:EBI-13044|uniprotkb:D6VUC1|ensemblfungi:YGL016W intact:EBI-20563|uniprotkb:O00041|uniprotkb:D6W2T4|ensemblfungi:YOR230W psi-mi:ka122_yeast(display_long)|uniprotkb:KAP122(gene name)|psi-mi:KAP122(display_short)|uniprotkb:PDR6(gene name synonym)|uniprotkb:Karyopherin-122(gene name synonym)|uniprotkb:Pleiotropic drug resistance regulatory protein 6(gene name synonym)|uniprotkb:YGL016W(locus name) psi-mi:wtm1_yeast(display_long)|uniprotkb:WTM1(gene name)|psi-mi:WTM1(display_short)|uniprotkb:YOR50-20(orf name)|uniprotkb:YOR230W(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16432237|doi:10.1073/pnas.0510516103|imex:IM-23401 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15565926|imex:IM-23401-2|dip:DIP-197440E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011499.1|sgd:S000002984|mint:P32767|dip:DIP-2449N|ensemblfungi:YGL016W(gene)|ensemblfungi:YGL016W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008361"(regulation of cell size)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|rcsb pdb:6Q82|rcsb pdb:6Q83|rcsb pdb:6Q84 refseq:NP_014873.3|sgd:S000005756|ensemblfungi:YOR230W(gene)|ensemblfungi:YOR230W_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-4558N|mint:Q12363 psi-mi:"MI:0465"(dip) crc64:EEBC5ADD4E16D9D3 crc64:C3E3822DABB53AEC full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:azK0CUm6ZvPpkaHa6uwppETz9iI559292 rogid:CwDzANIN+3kwYw1ikCUNqyWHD6s559292 rigid:1RADNW0r7tuC0du03C9c7FFsX9c false myc tag:c-c ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12363 uniprotkb:P49723 intact:EBI-20563|uniprotkb:O00041|uniprotkb:D6W2T4|ensemblfungi:YOR230W intact:EBI-15251|uniprotkb:Q66R92|uniprotkb:D6VUW4|ensemblfungi:YGR180C psi-mi:wtm1_yeast(display_long)|uniprotkb:WTM1(gene name)|psi-mi:WTM1(display_short)|uniprotkb:YOR50-20(orf name)|uniprotkb:YOR230W(locus name) psi-mi:rir4_yeast(display_long)|uniprotkb:RNR4(gene name)|psi-mi:RNR4(display_short)|uniprotkb:YGR180C(locus name)|uniprotkb:CRT3(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 2(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16432237|doi:10.1073/pnas.0510516103|imex:IM-23401 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15565968|imex:IM-23401-4|dip:DIP-197442E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014873.3|sgd:S000005756|ensemblfungi:YOR230W(gene)|ensemblfungi:YOR230W_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-4558N|mint:Q12363 sgd:S000003412|refseq:NP_011696.3|ensemblfungi:YGR180C(gene)|ensemblfungi:YGR180C_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMS|rcsb pdb:1ZZD|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|dip:DIP-5381N|mint:P49723 psi-mi:"MI:0465"(dip) crc64:C3E3822DABB53AEC crc64:712853F2D87D3972 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:CwDzANIN+3kwYw1ikCUNqyWHD6s559292 rogid:/Mx5xMzGpJSBsCDX8nwJMacQ6d4559292 rigid:xJragnm7CXk/hNHt92pQIDyY9/A false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q12363 uniprotkb:P09938 intact:EBI-20563|uniprotkb:O00041|uniprotkb:D6W2T4|ensemblfungi:YOR230W intact:EBI-15240|uniprotkb:D6VWF6|ensemblfungi:YJL026W psi-mi:wtm1_yeast(display_long)|uniprotkb:WTM1(gene name)|psi-mi:WTM1(display_short)|uniprotkb:YOR50-20(orf name)|uniprotkb:YOR230W(locus name) psi-mi:rir2_yeast(display_long)|uniprotkb:RNR2(gene name)|psi-mi:RNR2(display_short)|uniprotkb:YJL026W(locus name)|uniprotkb:J1271(orf name)|uniprotkb:CRT6(gene name synonym)|uniprotkb:Ribonucleotide reductase small subunit 1(gene name synonym)|uniprotkb:Ribonucleotide reductase R2 subunit 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Zhang et al. (2006) pubmed:16432237|doi:10.1073/pnas.0510516103|imex:IM-23401 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15565968|imex:IM-23401-4|dip:DIP-197442E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014873.3|sgd:S000005756|ensemblfungi:YOR230W(gene)|ensemblfungi:YOR230W_mRNA(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010674"(negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-SCE-3214815|reactome:R-SCE-3214847|reactome:R-SCE-3214858|dip:DIP-4558N|mint:Q12363 refseq:NP_012508.1|sgd:S000003563|ensemblfungi:YJL026W(gene)|ensemblfungi:YJL026W_mRNA(transcript)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006260"(DNA replication)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000358(Ribonucleotide reductase)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012348(Ribonucleotide reductase-related)|interpro:IPR030475|interpro:IPR033909|rcsb pdb:1JK0|rcsb pdb:1SMQ|rcsb pdb:2CVY|dip:DIP-5671N|mint:P09938 psi-mi:"MI:0465"(dip) crc64:C3E3822DABB53AEC crc64:DB98028408292042 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:CwDzANIN+3kwYw1ikCUNqyWHD6s559292 rogid:zIstTOUyVTqmrwFDunMD6a4T4V8559292 rigid:xJragnm7CXk/hNHt92pQIDyY9/A false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)