#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35439	uniprotkb:P18901	intact:EBI-877897|ensembl:ENSRNOP00000049198|uniprotkb:Q62646	intact:EBI-15563390|uniprotkb:P21669	psi-mi:nmdz1_rat(display_long)|uniprotkb:N-methyl-D-aspartate receptor subunit NR1(gene name synonym)|uniprotkb:Grin1(gene name)|psi-mi:Grin1(display_short)|uniprotkb:Nmdar1(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit zeta-1(gene name synonym)	psi-mi:drd1_rat(display_long)|uniprotkb:Drd1(gene name)|psi-mi:Drd1(display_short)|uniprotkb:Drd1a(gene name synonym)|uniprotkb:Dopamine D1 receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Scott et al. (2006)	pubmed:16407151|doi:10.1073/pnas.0505557103|imex:IM-23391	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15563476|imex:IM-23391-1|dip:DIP-197427E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010646"(regulation of cell communication)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0018964"(propylene metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021586"(pons maturation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0035176"(social behavior)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043278"(response to morphine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|ensembl:ENSRNOG00000011726(gene)|ensembl:ENSRNOT00000049297(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|rgd:2736|refseq:NP_058706.1|refseq:NP_001274352.1|refseq:NP_001257531.1|refseq:NP_001257532.1|refseq:NP_001257534.1|refseq:NP_001257537.1|refseq:NP_001257539.1|dip:DIP-674N|go:"GO:0045471"(response to ethanol)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060179"(male mating behavior)|go:"GO:0060992"(response to fungicide)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1905429"(response to glycine)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018882|interpro:IPR019594|interpro:IPR028082|mint:P35439|rcsb pdb:1PB7|rcsb pdb:1PB8|rcsb pdb:1PB9|rcsb pdb:1PBQ|rcsb pdb:1Y1M|rcsb pdb:1Y1Z|rcsb pdb:1Y20|rcsb pdb:2A5T|rcsb pdb:3Q41|rcsb pdb:4KCC|rcsb pdb:4KFQ|rcsb pdb:4NF4|rcsb pdb:4NF5|rcsb pdb:4NF6|rcsb pdb:4NF8|rcsb pdb:4PE5|rcsb pdb:5DEX|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5I56|rcsb pdb:5I57|rcsb pdb:5I58|rcsb pdb:5I59|rcsb pdb:5JTY|rcsb pdb:5U8C|rcsb pdb:5VIH|rcsb pdb:5VII|rcsb pdb:5VIJ|rcsb pdb:6CNA|rcsb pdb:6MM9|rcsb pdb:6MMA|rcsb pdb:6MMB|rcsb pdb:6MMG|rcsb pdb:6MMH|rcsb pdb:6MMI|rcsb pdb:6MMJ|rcsb pdb:6MMK|rcsb pdb:6MML|rcsb pdb:6MMM|rcsb pdb:6MMN|rcsb pdb:6MMP|rcsb pdb:6MMR|rcsb pdb:6MMS|rcsb pdb:6MMT|rcsb pdb:6MMU|rcsb pdb:6MMV|rcsb pdb:6MMW|rcsb pdb:6MMX|rcsb pdb:6OVD|rcsb pdb:6OVE|rcsb pdb:6USU|rcsb pdb:6USV|rcsb pdb:6UZ6|rcsb pdb:6UZG|rcsb pdb:6UZR|rcsb pdb:6UZW|rcsb pdb:6UZX|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736	go:"GO:0001588"(dopamine neurotransmitter receptor activity, coupled via Gs)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0046323"(glucose import)|go:"GO:0046959"(habituation)|go:"GO:0046960"(sensitization)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099010"(modification of postsynaptic structure)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000253"(positive regulation of feeding behavior)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000929(Dopamine receptor)|interpro:IPR001413(Dopamine 1A receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007617"(mating behavior)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0007628"(adult walking behavior)|go:"GO:0007631"(feeding behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004952"(dopamine neurotransmitter receptor activity)|go:"GO:0004993"(G protein-coupled serotonin receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005929"(cilium)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0014002"(astrocyte development)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0015872"(dopamine transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021853"(cerebral cortex GABAergic interneuron migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030594"(neurotransmitter receptor activity)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031750"(D3 dopamine receptor binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035094"(response to nicotine)|go:"GO:0035106"(operant conditioning)|go:"GO:0035176"(social behavior)|go:"GO:0035240"(dopamine binding)|go:"GO:0042053"(regulation of dopamine metabolic process)|go:"GO:0042220"(response to cocaine)|go:"GO:0042311"(vasodilation)|go:"GO:0042321"(negative regulation of circadian sleep/wake cycle, sleep)|go:"GO:0042493"|go:"GO:0042711"(maternal behavior)|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043200"(response to amino acid)|go:"GO:0043269"(regulation of ion transport)|go:"GO:0043278"(response to morphine)|go:"GO:0043679"(axon terminus)|go:"GO:0043987"(histone H3-S10 phosphorylation)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0032094"(response to food)|rgd:2518|dip:DIP-49024N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:zp3bKY55ROKfZfbAfhNN53skUYY10116	rogid:vhBRmUdLUoVE+2pVaC1H8Zi28hw10116	rigid:Ro5jqqrvhcg1blaey+xciUoksiE	false	-	sufficient binding region:387-416|glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)