#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q15545 uniprotkb:Q80UV9-1 intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709 intact:EBI-15563115 psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym) psi-mi:q80uv9-1(display_long)|uniprotkb:Taf1(gene name)|psi-mi:Taf1(display_short)|uniprotkb:Ccg1(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Gegonne et al. (2006) pubmed:16407123|doi:10.1073/pnas.0510031103|imex:IM-23388 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15563125|imex:IM-23388-1|dip:DIP-197421E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 intact:EBI-12684655(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606 rogid:UzbohKGbpTmDAGgLnaZVVZv1AvI10090 rigid:Sa2A10jpgpYuAtVJC1/3XbIZLyM false glutathione s tranferase tag:n-n flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q80UV9-1 uniprotkb:Q80UV9-1 intact:EBI-15563115 intact:EBI-15563115 psi-mi:q80uv9-1(display_long)|uniprotkb:Taf1(gene name)|psi-mi:Taf1(display_short)|uniprotkb:Ccg1(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym) psi-mi:q80uv9-1(display_long)|uniprotkb:Taf1(gene name)|psi-mi:Taf1(display_short)|uniprotkb:Ccg1(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Gegonne et al. (2006) pubmed:16407123|doi:10.1073/pnas.0510031103|imex:IM-23388 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-15563148|imex:IM-23388-2|dip:DIP-197422E - - psi-mi:"MI:0898"(putative self) psi-mi:"MI:0898"(putative self) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-12684655(isoform-parent) intact:EBI-12684655(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:UzbohKGbpTmDAGgLnaZVVZv1AvI10090 rogid:UzbohKGbpTmDAGgLnaZVVZv1AvI10090 rigid:+lCAxuw/VGj7PB9t2/llHrH2Wbk false - - - 0 psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q15545 uniprotkb:Q80UV9-1 intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709 intact:EBI-15563115 psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym) psi-mi:q80uv9-1(display_long)|uniprotkb:Taf1(gene name)|psi-mi:Taf1(display_short)|uniprotkb:Ccg1(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Gegonne et al. (2006) pubmed:16407123|doi:10.1073/pnas.0510031103|imex:IM-23388 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0465"(DIP) intact:EBI-15563164|imex:IM-23388-3|dip:DIP-197421E - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 intact:EBI-12684655(isoform-parent) psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606 rogid:UzbohKGbpTmDAGgLnaZVVZv1AvI10090 rigid:Sa2A10jpgpYuAtVJC1/3XbIZLyM false sufficient binding region:204-349 - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)