#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q92889 uniprotkb:P07992 intact:EBI-2370770|uniprotkb:O00140|uniprotkb:Q8TD83|uniprotkb:A5PKV6|uniprotkb:A8K111|ensembl:ENSP00000310520 intact:EBI-750962|ensembl:ENSP00000300853|ensembl:ENSP00000468035|uniprotkb:B2RC01|uniprotkb:B3KRR0|uniprotkb:Q7Z7F5|uniprotkb:Q96S40 psi-mi:xpf_human(display_long)|uniprotkb:ERCC4(gene name)|psi-mi:ERCC4(display_short)|uniprotkb:ERCC11(gene name synonym)|uniprotkb:XPF(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-4(gene name synonym)|uniprotkb:DNA repair protein complementing XP-F cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group F-complementing protein(gene name synonym) psi-mi:ercc1_human(display_long)|uniprotkb:ERCC1(gene name)|psi-mi:ERCC1(display_short) psi-mi:"MI:0096"(pull down) Tripsianes et al. (2005) pubmed:16338413|doi:10.1016/j.str.2005.08.014|imex:IM-14233 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15561213|imex:IM-14233-1|dip:DIP-102961E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005227.1|dip:DIP-42006N|ensembl:ENSG00000175595(gene)|ensembl:ENST00000311895(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1901255"(nucleotide-excision repair involved in interstrand cross-link repair)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1905768"(negative regulation of double-stranded telomeric DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006167(DNA repair protein)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|mint:Q92889|rcsb pdb:1Z00|rcsb pdb:2A1J|rcsb pdb:2AQ0|rcsb pdb:2KN7|rcsb pdb:2MUT|rcsb pdb:6SXA|rcsb pdb:6SXB|reactome:R-HSA-5685938|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6783310 refseq:NP_001974.1|ensembl:ENSG00000012061(gene)|ensembl:ENST00000300853(transcript)|ensembl:ENST00000589165(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|refseq:XP_011524912.1|refseq:NP_001159521.1|refseq:NP_973730.1|refseq:XP_005258691.1|refseq:XP_005258692.1|refseq:XP_005258693.1|refseq:XP_016881948.1|refseq:XP_016881949.1|refseq:XP_016881950.1|refseq:XP_016881951.1|refseq:XP_016881952.1|refseq:XP_016881953.1|refseq:XP_016881954.1|refseq:XP_016881955.1|dip:DIP-24235N|reactome:R-HSA-6783310|reactome:R-HSA-6782135|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006949"(syncytium formation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009650"(UV protection)|go:"GO:0009744"(response to sucrose)|go:"GO:0010165"(response to X-ray)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045190"(isotype switching)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048477"(oogenesis)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:1904431"(positive regulation of t-circle formation)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR004579(DNA repair protein rad10)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|rcsb pdb:1Z00|rcsb pdb:2A1I|rcsb pdb:2A1J|rcsb pdb:2JNW|rcsb pdb:2JPD|rcsb pdb:2MUT|rcsb pdb:6SXA|rcsb pdb:6SXB|reactome:R-HSA-5685938|reactome:R-HSA-5696395|reactome:R-HSA-5696400 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:A42t082dZNQH72TF3QRa+Msuoms9606 rogid:wgacfBH+F2NRhpzRsTChE4zSPho9606 rigid:+gWkM4c7rKvMZTNqEI2b/PThZxE false binding-associated region:823-905 binding-associated region:220-297|his tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92889 uniprotkb:P07992 intact:EBI-2370770|uniprotkb:O00140|uniprotkb:Q8TD83|uniprotkb:A5PKV6|uniprotkb:A8K111|ensembl:ENSP00000310520 intact:EBI-750962|ensembl:ENSP00000300853|ensembl:ENSP00000468035|uniprotkb:B2RC01|uniprotkb:B3KRR0|uniprotkb:Q7Z7F5|uniprotkb:Q96S40 psi-mi:xpf_human(display_long)|uniprotkb:ERCC4(gene name)|psi-mi:ERCC4(display_short)|uniprotkb:ERCC11(gene name synonym)|uniprotkb:XPF(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-4(gene name synonym)|uniprotkb:DNA repair protein complementing XP-F cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group F-complementing protein(gene name synonym) psi-mi:ercc1_human(display_long)|uniprotkb:ERCC1(gene name)|psi-mi:ERCC1(display_short) psi-mi:"MI:0077"(nuclear magnetic resonance) Tripsianes et al. (2005) pubmed:16338413|doi:10.1016/j.str.2005.08.014|imex:IM-14233 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15561237|imex:IM-14233-2|dip:DIP-102961E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005227.1|dip:DIP-42006N|ensembl:ENSG00000175595(gene)|ensembl:ENST00000311895(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1901255"(nucleotide-excision repair involved in interstrand cross-link repair)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1905768"(negative regulation of double-stranded telomeric DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006167(DNA repair protein)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|mint:Q92889|rcsb pdb:1Z00|rcsb pdb:2A1J|rcsb pdb:2AQ0|rcsb pdb:2KN7|rcsb pdb:2MUT|rcsb pdb:6SXA|rcsb pdb:6SXB|reactome:R-HSA-5685938|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6783310 refseq:NP_001974.1|ensembl:ENSG00000012061(gene)|ensembl:ENST00000300853(transcript)|ensembl:ENST00000589165(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|refseq:XP_011524912.1|refseq:NP_001159521.1|refseq:NP_973730.1|refseq:XP_005258691.1|refseq:XP_005258692.1|refseq:XP_005258693.1|refseq:XP_016881948.1|refseq:XP_016881949.1|refseq:XP_016881950.1|refseq:XP_016881951.1|refseq:XP_016881952.1|refseq:XP_016881953.1|refseq:XP_016881954.1|refseq:XP_016881955.1|dip:DIP-24235N|reactome:R-HSA-6783310|reactome:R-HSA-6782135|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006949"(syncytium formation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009650"(UV protection)|go:"GO:0009744"(response to sucrose)|go:"GO:0010165"(response to X-ray)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045190"(isotype switching)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048477"(oogenesis)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:1904431"(positive regulation of t-circle formation)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR004579(DNA repair protein rad10)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|rcsb pdb:1Z00|rcsb pdb:2A1I|rcsb pdb:2A1J|rcsb pdb:2JNW|rcsb pdb:2JPD|rcsb pdb:2MUT|rcsb pdb:6SXA|rcsb pdb:6SXB|reactome:R-HSA-5685938|reactome:R-HSA-5696395|reactome:R-HSA-5696400 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:A42t082dZNQH72TF3QRa+Msuoms9606 rogid:wgacfBH+F2NRhpzRsTChE4zSPho9606 rigid:+gWkM4c7rKvMZTNqEI2b/PThZxE false binding-associated region:823-905 binding-associated region:220-297 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q92889 uniprotkb:P07992 intact:EBI-2370770|uniprotkb:O00140|uniprotkb:Q8TD83|uniprotkb:A5PKV6|uniprotkb:A8K111|ensembl:ENSP00000310520 intact:EBI-750962|ensembl:ENSP00000300853|ensembl:ENSP00000468035|uniprotkb:B2RC01|uniprotkb:B3KRR0|uniprotkb:Q7Z7F5|uniprotkb:Q96S40 psi-mi:xpf_human(display_long)|uniprotkb:ERCC4(gene name)|psi-mi:ERCC4(display_short)|uniprotkb:ERCC11(gene name synonym)|uniprotkb:XPF(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-4(gene name synonym)|uniprotkb:DNA repair protein complementing XP-F cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group F-complementing protein(gene name synonym) psi-mi:ercc1_human(display_long)|uniprotkb:ERCC1(gene name)|psi-mi:ERCC1(display_short) psi-mi:"MI:0071"(molecular sieving) Tripsianes et al. (2005) pubmed:16338413|doi:10.1016/j.str.2005.08.014|imex:IM-14233 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15561258|imex:IM-14233-3|dip:DIP-102961E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005227.1|dip:DIP-42006N|ensembl:ENSG00000175595(gene)|ensembl:ENST00000311895(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1901255"(nucleotide-excision repair involved in interstrand cross-link repair)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1905768"(negative regulation of double-stranded telomeric DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006167(DNA repair protein)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|mint:Q92889|rcsb pdb:1Z00|rcsb pdb:2A1J|rcsb pdb:2AQ0|rcsb pdb:2KN7|rcsb pdb:2MUT|rcsb pdb:6SXA|rcsb pdb:6SXB|reactome:R-HSA-5685938|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6783310 refseq:NP_001974.1|ensembl:ENSG00000012061(gene)|ensembl:ENST00000300853(transcript)|ensembl:ENST00000589165(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|refseq:XP_011524912.1|refseq:NP_001159521.1|refseq:NP_973730.1|refseq:XP_005258691.1|refseq:XP_005258692.1|refseq:XP_005258693.1|refseq:XP_016881948.1|refseq:XP_016881949.1|refseq:XP_016881950.1|refseq:XP_016881951.1|refseq:XP_016881952.1|refseq:XP_016881953.1|refseq:XP_016881954.1|refseq:XP_016881955.1|dip:DIP-24235N|reactome:R-HSA-6783310|reactome:R-HSA-6782135|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006949"(syncytium formation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007584"(response to nutrient)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009650"(UV protection)|go:"GO:0009744"(response to sucrose)|go:"GO:0010165"(response to X-ray)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0035166"(post-embryonic hemopoiesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0045190"(isotype switching)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048477"(oogenesis)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0090399"(replicative senescence)|go:"GO:0090656"(t-circle formation)|go:"GO:1904431"(positive regulation of t-circle formation)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR004579(DNA repair protein rad10)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|rcsb pdb:1Z00|rcsb pdb:2A1I|rcsb pdb:2A1J|rcsb pdb:2JNW|rcsb pdb:2JPD|rcsb pdb:2MUT|rcsb pdb:6SXA|rcsb pdb:6SXB|reactome:R-HSA-5685938|reactome:R-HSA-5696395|reactome:R-HSA-5696400 psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:A42t082dZNQH72TF3QRa+Msuoms9606 rogid:wgacfBH+F2NRhpzRsTChE4zSPho9606 rigid:+gWkM4c7rKvMZTNqEI2b/PThZxE false binding-associated region:823-905 binding-associated region:220-297 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)