#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04911 uniprotkb:Q9VKM6 intact:EBI-8072|uniprotkb:D6VSK7|ensemblfungi:YDR225W intact:EBI-116977|ensemblmetazoa:FBpp0079735|ensemblmetazoa:FBpp0309447 psi-mi:h2a1_yeast(display_long)|uniprotkb:HTA1(gene name)|psi-mi:HTA1(display_short)|uniprotkb:H2A1(gene name synonym)|uniprotkb:SPT11(gene name synonym)|uniprotkb:YDR225W(locus name)|uniprotkb:YD9934.10(orf name) psi-mi:vps72_drome(display_long)|uniprotkb:CG4621(orf name)|uniprotkb:YL-1(gene name)|psi-mi:YL-1(display_short)|uniprotkb:Protein YL-1(gene name synonym) psi-mi:"MI:0096"(pull down) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560042|imex:IM-21783-3|dip:DIP-192199E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002633|refseq:NP_010511.3|mint:P04911|dip:DIP-419N|ensemblfungi:YDR225W(gene)|ensemblfungi:YDR225W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006342"|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:1ID3|rcsb pdb:3T7K|rcsb pdb:4WNN|rcsb pdb:5BT1|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:7K78|rcsb pdb:7K7G ensemblmetazoa:FBgn0032321(gene)|ensemblmetazoa:FBtr0080146(transcript)|ensemblmetazoa:FBtr0340549(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|interpro:IPR008895(YL1 nuclear)|interpro:IPR013272(YL1 nuclear, C-terminal)|rcsb pdb:5CHL|refseq:NP_609475.1|flybase:FBgn0032321|refseq:NP_001285823.1 psi-mi:"MI:0465"(dip) crc64:A908C94A0363D13F - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:UDqMGCE7Vq/Mgg0SQUjZ9M6Ht8U559292 rogid:3b99eJuEpzabWZC0tJV3smcAdcY7227 rigid:g0oXkRtbvtAI1UD1jbYjuWl8mic false flag tag:c-c his tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P53201 uniprotkb:Q05471 intact:EBI-23061|uniprotkb:D6VUD9|ensemblfungi:YGR002C intact:EBI-22102|uniprotkb:D6VSW6|ensemblfungi:YDR334W psi-mi:swc4_yeast(display_long)|uniprotkb:SWC4(gene name)|psi-mi:SWC4(display_short)|uniprotkb:EAF2(gene name synonym)|uniprotkb:GOD1(gene name synonym)|uniprotkb:ESA1-associated factor 2(gene name synonym)|uniprotkb:YGR002C(locus name) psi-mi:swr1_yeast(display_long)|uniprotkb:Swi2/Snf2-related 1(gene name synonym)|uniprotkb:SWR1(gene name)|psi-mi:SWR1(display_short)|uniprotkb:YDR334W(locus name)|uniprotkb:D9651.6(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560021|imex:IM-21783-2|dip:DIP-80490E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011516.1|sgd:S000003234|dip:DIP-6510N|mint:P53201|ensemblfungi:YGR002C(gene)|ensemblfungi:YGR002C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0051276"(chromosome organization)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR027109|interpro:IPR032563 refseq:NP_010621.1|sgd:S000002742|dip:DIP-2845N|ensemblfungi:YDR334W(gene)|ensemblfungi:YDR334W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:4M6B|rcsb pdb:5I9E|rcsb pdb:6GEJ|rcsb pdb:6GEN|mint:Q05471 psi-mi:"MI:0465"(dip) crc64:512CB8DF3171E7A3 crc64:156E3BB5978905C8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:sWHtRrziTd67BY1nQ1IPX/S8l/I559292 rogid:Lo9+YZNnIZlJ8/Tq7XW3lDjUsBQ559292 rigid:2OZNkvjP/TB16JKysxHBKZlKW8Q false - necessary binding region:278-681|flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03388 uniprotkb:Q12692 intact:EBI-38035|uniprotkb:D6VTA8|ensemblfungi:YDR485C intact:EBI-8080|uniprotkb:D6W255|ensemblfungi:YOL012C psi-mi:vps72_yeast(display_long)|uniprotkb:SWR complex protein 2(gene name synonym)|uniprotkb:VPS72(gene name)|psi-mi:VPS72(display_short)|uniprotkb:SWC2(gene name synonym)|uniprotkb:YDR485C(locus name) psi-mi:h2az_yeast(display_long)|uniprotkb:HTZ1(gene name)|psi-mi:HTZ1(display_short)|uniprotkb:H2AZ(gene name synonym)|uniprotkb:YOL012C(locus name)|uniprotkb:HTA3(gene name synonym)|uniprotkb:O2345(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560002|imex:IM-21783-1|dip:DIP-86844E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002893|refseq:NP_010773.4|mint:Q03388|dip:DIP-1008N|ensemblfungi:YDR485C(gene)|ensemblfungi:YDR485C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|interpro:IPR008895(YL1 nuclear)|interpro:IPR013272(YL1 nuclear, C-terminal) refseq:NP_014631.1|sgd:S000005372|mint:Q12692|dip:DIP-1381N|ensemblfungi:YOL012C(gene)|ensemblfungi:YOL012C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2FSB|rcsb pdb:2JSS|rcsb pdb:4M6B|rcsb pdb:5J9Q|rcsb pdb:6AE8|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-9018519 psi-mi:"MI:0465"(dip) crc64:6D3053EBB610DB95 crc64:1D8FCEE3C8A504E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:5TdXjS2mNOhwsWXE2wSqCZHIw24559292 rogid:WNtmWZ+w+lXKNqAqIp0T4u28siw559292 rigid:JxDy9Voy0YSNXbH04rSrvy/83M4 false flag tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q03388 uniprotkb:Q12692 intact:EBI-38035|uniprotkb:D6VTA8|ensemblfungi:YDR485C intact:EBI-8080|uniprotkb:D6W255|ensemblfungi:YOL012C psi-mi:vps72_yeast(display_long)|uniprotkb:SWR complex protein 2(gene name synonym)|uniprotkb:VPS72(gene name)|psi-mi:VPS72(display_short)|uniprotkb:SWC2(gene name synonym)|uniprotkb:YDR485C(locus name) psi-mi:h2az_yeast(display_long)|uniprotkb:HTZ1(gene name)|psi-mi:HTZ1(display_short)|uniprotkb:H2AZ(gene name synonym)|uniprotkb:YOL012C(locus name)|uniprotkb:HTA3(gene name synonym)|uniprotkb:O2345(orf name) psi-mi:"MI:0096"(pull down) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560122|imex:IM-21783-7|dip:DIP-86844E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002893|refseq:NP_010773.4|mint:Q03388|dip:DIP-1008N|ensemblfungi:YDR485C(gene)|ensemblfungi:YDR485C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|interpro:IPR008895(YL1 nuclear)|interpro:IPR013272(YL1 nuclear, C-terminal) refseq:NP_014631.1|sgd:S000005372|mint:Q12692|dip:DIP-1381N|ensemblfungi:YOL012C(gene)|ensemblfungi:YOL012C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2FSB|rcsb pdb:2JSS|rcsb pdb:4M6B|rcsb pdb:5J9Q|rcsb pdb:6AE8|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-9018519 psi-mi:"MI:0465"(dip) crc64:6D3053EBB610DB95 crc64:1D8FCEE3C8A504E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:5TdXjS2mNOhwsWXE2wSqCZHIw24559292 rogid:WNtmWZ+w+lXKNqAqIp0T4u28siw559292 rigid:JxDy9Voy0YSNXbH04rSrvy/83M4 false sufficient binding region:1-281|sufficient binding region:345-795|his tag:c-c flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9VKM6 uniprotkb:Q12692 intact:EBI-116977|ensemblmetazoa:FBpp0079735|ensemblmetazoa:FBpp0309447 intact:EBI-8080|uniprotkb:D6W255|ensemblfungi:YOL012C psi-mi:vps72_drome(display_long)|uniprotkb:CG4621(orf name)|uniprotkb:YL-1(gene name)|psi-mi:YL-1(display_short)|uniprotkb:Protein YL-1(gene name synonym) psi-mi:h2az_yeast(display_long)|uniprotkb:HTZ1(gene name)|psi-mi:HTZ1(display_short)|uniprotkb:H2AZ(gene name synonym)|uniprotkb:YOL012C(locus name)|uniprotkb:HTA3(gene name synonym)|uniprotkb:O2345(orf name) psi-mi:"MI:0096"(pull down) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560147|imex:IM-21783-8|dip:DIP-192198E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblmetazoa:FBgn0032321(gene)|ensemblmetazoa:FBtr0080146(transcript)|ensemblmetazoa:FBtr0340549(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043486"(histone exchange)|interpro:IPR008895(YL1 nuclear)|interpro:IPR013272(YL1 nuclear, C-terminal)|rcsb pdb:5CHL|refseq:NP_609475.1|flybase:FBgn0032321|refseq:NP_001285823.1 refseq:NP_014631.1|sgd:S000005372|mint:Q12692|dip:DIP-1381N|ensemblfungi:YOL012C(gene)|ensemblfungi:YOL012C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2FSB|rcsb pdb:2JSS|rcsb pdb:4M6B|rcsb pdb:5J9Q|rcsb pdb:6AE8|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-9018519 psi-mi:"MI:0465"(dip) - crc64:1D8FCEE3C8A504E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:3b99eJuEpzabWZC0tJV3smcAdcY7227 rogid:WNtmWZ+w+lXKNqAqIp0T4u28siw559292 rigid:m7+22uEVP+wQ2zCE7HOE2dAv2yY false his tag:c-c flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04911 uniprotkb:Q03388 intact:EBI-8072|uniprotkb:D6VSK7|ensemblfungi:YDR225W intact:EBI-38035|uniprotkb:D6VTA8|ensemblfungi:YDR485C psi-mi:h2a1_yeast(display_long)|uniprotkb:HTA1(gene name)|psi-mi:HTA1(display_short)|uniprotkb:H2A1(gene name synonym)|uniprotkb:SPT11(gene name synonym)|uniprotkb:YDR225W(locus name)|uniprotkb:YD9934.10(orf name) psi-mi:vps72_yeast(display_long)|uniprotkb:SWR complex protein 2(gene name synonym)|uniprotkb:VPS72(gene name)|psi-mi:VPS72(display_short)|uniprotkb:SWC2(gene name synonym)|uniprotkb:YDR485C(locus name) psi-mi:"MI:0096"(pull down) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560168|imex:IM-21783-9|dip:DIP-102789E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002633|refseq:NP_010511.3|mint:P04911|dip:DIP-419N|ensemblfungi:YDR225W(gene)|ensemblfungi:YDR225W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006281"(DNA repair)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006342"|go:"GO:0031298"(replication fork protection complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:1ID3|rcsb pdb:3T7K|rcsb pdb:4WNN|rcsb pdb:5BT1|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:7K78|rcsb pdb:7K7G sgd:S000002893|refseq:NP_010773.4|mint:Q03388|dip:DIP-1008N|ensemblfungi:YDR485C(gene)|ensemblfungi:YDR485C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|interpro:IPR008895(YL1 nuclear)|interpro:IPR013272(YL1 nuclear, C-terminal) psi-mi:"MI:0465"(dip) crc64:A908C94A0363D13F crc64:6D3053EBB610DB95 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:UDqMGCE7Vq/Mgg0SQUjZ9M6Ht8U559292 rogid:5TdXjS2mNOhwsWXE2wSqCZHIw24559292 rigid:waqSOeaZ2id11+UdSXMGmrI9LJ4 false flag tag:c-c sufficient binding region:1-281|sufficient binding region:345-795|his tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q12509 uniprotkb:Q03433 intact:EBI-2957|uniprotkb:D6VY85|ensemblfungi:YLR085C intact:EBI-27814|uniprotkb:D6VZD4|ensemblfungi:YML041C psi-mi:arp6_yeast(display_long)|uniprotkb:ARP6(gene name)|psi-mi:ARP6(display_short)|uniprotkb:L2393(orf name)|uniprotkb:L9449.13(orf name)|uniprotkb:YLR085C(locus name) psi-mi:vps71_yeast(display_long)|uniprotkb:YML041C(locus name)|uniprotkb:YM8054.02C(orf name)|uniprotkb:VPS71(gene name)|psi-mi:VPS71(display_short)|uniprotkb:SWC6(gene name synonym)|uniprotkb:SWR complex protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560103|imex:IM-21783-6|dip:DIP-86719E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013186.1|sgd:S000004075|dip:DIP-5169N|mint:Q12509|ensemblfungi:YLR085C(gene)|ensemblfungi:YLR085C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031491"(nucleosome binding)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043486"(histone exchange)|interpro:IPR004000(Actin/actin-like)|interpro:IPR030054|interpro:IPR043129|rcsb pdb:6GEJ|rcsb pdb:6GEN refseq:NP_013671.1|sgd:S000004505|dip:DIP-4074N|mint:Q03433|ensemblfungi:YML041C(gene)|ensemblfungi:YML041C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043486"(histone exchange)|go:"GO:0046872"(metal ion binding)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR039723|rcsb pdb:6GEJ|rcsb pdb:6GEN psi-mi:"MI:0465"(dip) crc64:92D201F62D04232B crc64:D95B57C72ACB648A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:eUSaoZM9qSU38jE6fCq/RC1DlC8559292 rogid:EqmxUltQbEH6gtsH/ES7PM15Id8559292 rigid:L2NsKZET59qpFVpiVTWF+iRkSFA false - flag tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03433 uniprotkb:Q12692 intact:EBI-27814|uniprotkb:D6VZD4|ensemblfungi:YML041C intact:EBI-8080|uniprotkb:D6W255|ensemblfungi:YOL012C psi-mi:vps71_yeast(display_long)|uniprotkb:YML041C(locus name)|uniprotkb:YM8054.02C(orf name)|uniprotkb:VPS71(gene name)|psi-mi:VPS71(display_short)|uniprotkb:SWC6(gene name synonym)|uniprotkb:SWR complex protein 6(gene name synonym) psi-mi:h2az_yeast(display_long)|uniprotkb:HTZ1(gene name)|psi-mi:HTZ1(display_short)|uniprotkb:H2AZ(gene name synonym)|uniprotkb:YOL012C(locus name)|uniprotkb:HTA3(gene name synonym)|uniprotkb:O2345(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560084|imex:IM-21783-5|dip:DIP-86849E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013671.1|sgd:S000004505|dip:DIP-4074N|mint:Q03433|ensemblfungi:YML041C(gene)|ensemblfungi:YML041C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043486"(histone exchange)|go:"GO:0046872"(metal ion binding)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR039723|rcsb pdb:6GEJ|rcsb pdb:6GEN refseq:NP_014631.1|sgd:S000005372|mint:Q12692|dip:DIP-1381N|ensemblfungi:YOL012C(gene)|ensemblfungi:YOL012C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2FSB|rcsb pdb:2JSS|rcsb pdb:4M6B|rcsb pdb:5J9Q|rcsb pdb:6AE8|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-9018519 psi-mi:"MI:0465"(dip) crc64:D95B57C72ACB648A crc64:1D8FCEE3C8A504E7 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:EqmxUltQbEH6gtsH/ES7PM15Id8559292 rogid:WNtmWZ+w+lXKNqAqIp0T4u28siw559292 rigid:EHZ33QfRcIOoa6tHdJbP4xGXuhM false flag tag:c-c - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12692 uniprotkb:Q05471 intact:EBI-8080|uniprotkb:D6W255|ensemblfungi:YOL012C intact:EBI-22102|uniprotkb:D6VSW6|ensemblfungi:YDR334W psi-mi:h2az_yeast(display_long)|uniprotkb:HTZ1(gene name)|psi-mi:HTZ1(display_short)|uniprotkb:H2AZ(gene name synonym)|uniprotkb:YOL012C(locus name)|uniprotkb:HTA3(gene name synonym)|uniprotkb:O2345(orf name) psi-mi:swr1_yeast(display_long)|uniprotkb:Swi2/Snf2-related 1(gene name synonym)|uniprotkb:SWR1(gene name)|psi-mi:SWR1(display_short)|uniprotkb:YDR334W(locus name)|uniprotkb:D9651.6(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15560063|imex:IM-21783-4|dip:DIP-80493E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014631.1|sgd:S000005372|mint:Q12692|dip:DIP-1381N|ensemblfungi:YOL012C(gene)|ensemblfungi:YOL012C_mRNA(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006342"|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|rcsb pdb:2FSB|rcsb pdb:2JSS|rcsb pdb:4M6B|rcsb pdb:5J9Q|rcsb pdb:6AE8|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-9018519 refseq:NP_010621.1|sgd:S000002742|dip:DIP-2845N|ensemblfungi:YDR334W(gene)|ensemblfungi:YDR334W_mRNA(transcript)|go:"GO:0000725"(recombinational repair)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR027417|interpro:IPR038718|rcsb pdb:4M6B|rcsb pdb:5I9E|rcsb pdb:6GEJ|rcsb pdb:6GEN|mint:Q05471 psi-mi:"MI:0465"(dip) crc64:1D8FCEE3C8A504E7 crc64:156E3BB5978905C8 full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:WNtmWZ+w+lXKNqAqIp0T4u28siw559292 rogid:Lo9+YZNnIZlJ8/Tq7XW3lDjUsBQ559292 rigid:piqTT8c1Afr177q9zODaQtK+62E false ha tag:c-c flag tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q03388 uniprotkb:Q12509 intact:EBI-38035|uniprotkb:D6VTA8|ensemblfungi:YDR485C intact:EBI-2957|uniprotkb:D6VY85|ensemblfungi:YLR085C psi-mi:vps72_yeast(display_long)|uniprotkb:SWR complex protein 2(gene name synonym)|uniprotkb:VPS72(gene name)|psi-mi:VPS72(display_short)|uniprotkb:SWC2(gene name synonym)|uniprotkb:YDR485C(locus name) psi-mi:arp6_yeast(display_long)|uniprotkb:ARP6(gene name)|psi-mi:ARP6(display_short)|uniprotkb:L2393(orf name)|uniprotkb:L9449.13(orf name)|uniprotkb:YLR085C(locus name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15560193|imex:IM-21783-10|dip:DIP-192197E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002893|refseq:NP_010773.4|mint:Q03388|dip:DIP-1008N|ensemblfungi:YDR485C(gene)|ensemblfungi:YDR485C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|interpro:IPR008895(YL1 nuclear)|interpro:IPR013272(YL1 nuclear, C-terminal) refseq:NP_013186.1|sgd:S000004075|dip:DIP-5169N|mint:Q12509|ensemblfungi:YLR085C(gene)|ensemblfungi:YLR085C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031491"(nucleosome binding)|go:"GO:0034399"(nuclear periphery)|go:"GO:0043486"(histone exchange)|interpro:IPR004000(Actin/actin-like)|interpro:IPR030054|interpro:IPR043129|rcsb pdb:6GEJ|rcsb pdb:6GEN psi-mi:"MI:0465"(dip) crc64:6D3053EBB610DB95 crc64:92D201F62D04232B full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:5TdXjS2mNOhwsWXE2wSqCZHIw24559292 rogid:eUSaoZM9qSU38jE6fCq/RC1DlC8559292 rigid:b0rSNlyABqGrw+GkF/9iS/RellA false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q03388 uniprotkb:Q03433 intact:EBI-38035|uniprotkb:D6VTA8|ensemblfungi:YDR485C intact:EBI-27814|uniprotkb:D6VZD4|ensemblfungi:YML041C psi-mi:vps72_yeast(display_long)|uniprotkb:SWR complex protein 2(gene name synonym)|uniprotkb:VPS72(gene name)|psi-mi:VPS72(display_short)|uniprotkb:SWC2(gene name synonym)|uniprotkb:YDR485C(locus name) psi-mi:vps71_yeast(display_long)|uniprotkb:YML041C(locus name)|uniprotkb:YM8054.02C(orf name)|uniprotkb:VPS71(gene name)|psi-mi:VPS71(display_short)|uniprotkb:SWC6(gene name synonym)|uniprotkb:SWR complex protein 6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Wu et al. (2005) pubmed:16299513|doi:10.1038/nsmb1023|imex:IM-21783 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0914"(association) psi-mi:"MI:0465"(DIP) intact:EBI-15560193|imex:IM-21783-10|dip:DIP-192197E - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000002893|refseq:NP_010773.4|mint:Q03388|dip:DIP-1008N|ensemblfungi:YDR485C(gene)|ensemblfungi:YDR485C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|interpro:IPR008895(YL1 nuclear)|interpro:IPR013272(YL1 nuclear, C-terminal) refseq:NP_013671.1|sgd:S000004505|dip:DIP-4074N|mint:Q03433|ensemblfungi:YML041C(gene)|ensemblfungi:YML041C_mRNA(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031491"(nucleosome binding)|go:"GO:0043486"(histone exchange)|go:"GO:0046872"(metal ion binding)|interpro:IPR007529(Zinc finger, HIT-type)|interpro:IPR039723|rcsb pdb:6GEJ|rcsb pdb:6GEN psi-mi:"MI:0465"(dip) crc64:6D3053EBB610DB95 crc64:D95B57C72ACB648A full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2017/08/04 2017/08/10 rogid:5TdXjS2mNOhwsWXE2wSqCZHIw24559292 rogid:EqmxUltQbEH6gtsH/ES7PM15Id8559292 rigid:b0rSNlyABqGrw+GkF/9iS/RellA false flag tag:c-c - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)