#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O35157	uniprotkb:P11881	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559496|imex:IM-13625-3|dip:DIP-102615E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rigid:umovYZCnPY5fKkKeV45bRd8mp+I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O35157	uniprotkb:Q6PIE5	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559513|imex:IM-13625-4|dip:DIP-102619E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rigid:bO857DZDXyon9B2IXyCKMKQAL+M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35157	uniprotkb:P11881	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559461|imex:IM-13625-1|dip:DIP-102615E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rigid:umovYZCnPY5fKkKeV45bRd8mp+I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDN2	uniprotkb:O35157	intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09	intact:EBI-8351080|intact:MINT-4104623	psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559478|imex:IM-13625-2|dip:DIP-102621E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	psi-mi:"MI:0465"(dip)	-	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rigid:0ettppDSe9OYgVzUnmkQh4CRKmk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8VDN2	uniprotkb:P11881	intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559478|imex:IM-13625-2|dip:DIP-102621E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rigid:0ettppDSe9OYgVzUnmkQh4CRKmk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6PIE5	uniprotkb:P11881	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559605|imex:IM-13625-9|dip:DIP-102617E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rigid:pSzF3l7YU1fZxS3utaV1PjMA9Jw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q01484-2	uniprotkb:P32418	intact:EBI-941994|ensembl:ENSP00000378044	intact:EBI-2682189|uniprotkb:Q9UBL8|uniprotkb:Q9UDN1|uniprotkb:Q9UD55|uniprotkb:O95849|uniprotkb:Q587I6|uniprotkb:A8K6N1|uniprotkb:Q9UKX6|uniprotkb:Q9UDN2|uniprotkb:D6W595|ensembl:ENSP00000332931|ensembl:ENSP00000384763|uniprotkb:Q4QQG6|uniprotkb:Q59GN4	psi-mi:q01484-2(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:nac1_human(display_long)|uniprotkb:CNC(gene name synonym)|uniprotkb:NCX1(gene name synonym)|uniprotkb:"Na(+)/Ca(2+)-exchange protein 1"(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)|uniprotkb:SLC8A1(gene name)|psi-mi:SLC8A1(display_short)	psi-mi:"MI:0096"(pull down)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559582|imex:IM-13625-8|dip:DIP-102623E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-941975(ank2_human)|ensembl:ENSG00000145362(gene)|ensembl:ENST00000394537(transcript)	refseq:NP_001239553.1|refseq:XP_011531356.1|refseq:XP_011531357.1|refseq:XP_011531358.1|refseq:NP_001106271.1|refseq:NP_001106272.1|refseq:NP_001106273.1|refseq:NP_066920.1|refseq:XP_005264571.1|ensembl:ENSG00000183023(gene)|ensembl:ENST00000332839(transcript)|ensembl:ENST00000403092(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006936"(muscle contraction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0015491"("cation:cation antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0021537"(telencephalon development)|go:"GO:0030001"(metal ion transport)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0033198"(response to ATP)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044557"(relaxation of smooth muscle)|go:"GO:0045202"(synapse)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098794"(postsynapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099580"(ion antiporter activity involved in regulation of postsynaptic membrane potential)|go:"GO:1901660"(calcium ion export)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905060"("calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration")|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|refseq:XP_006712144.1|refseq:XP_006712145.1|refseq:XP_006712146.1|refseq:XP_006712147.1|refseq:XP_006712148.1|refseq:XP_016860235.1|refseq:XP_016860237.1|refseq:XP_016860238.1|refseq:XP_016860239.1|refseq:XP_016860240.1|refseq:XP_016860241.1|refseq:XP_016860242.1|refseq:XP_016860243.1|refseq:XP_016860247.1|dip:DIP-48356N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:e8xlbQGPZTukEz7l9hLOjjlgFxk9606	rogid:qx5nxfaXMDlhvCSwZi+EfEYV8rI9606	rigid:k4Bd+CD+SuIGxZSSrB6sqL2nQK4	false	binding-associated region:1-958|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q8VDN2	uniprotkb:P11881	intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559565|imex:IM-13625-7|dip:DIP-102616E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rigid:Sl6LG7k2YSphm8rrLubST2LXOaY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6PIE5	uniprotkb:O35157	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	intact:EBI-8351080|intact:MINT-4104623	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559547|imex:IM-13625-6|dip:DIP-102622E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	psi-mi:"MI:0465"(dip)	-	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rigid:bwtQY0/c9vgK7FuxzzW+3/iKI0k	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q6PIE5	uniprotkb:P11881	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559547|imex:IM-13625-6|dip:DIP-102622E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rigid:bwtQY0/c9vgK7FuxzzW+3/iKI0k	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35157	uniprotkb:Q6PIE5	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559622|imex:IM-13625-10|dip:DIP-102620E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rigid:+XZ8ENxIZFZfflppHwgxSzuthXI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35157	uniprotkb:P11881	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559622|imex:IM-13625-10|dip:DIP-102620E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rigid:+XZ8ENxIZFZfflppHwgxSzuthXI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35157	uniprotkb:Q8VDN2	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559622|imex:IM-13625-10|dip:DIP-102620E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090	rigid:+XZ8ENxIZFZfflppHwgxSzuthXI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35157	uniprotkb:Q6PIE5	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559530|imex:IM-13625-5|dip:DIP-102619E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rigid:bO857DZDXyon9B2IXyCKMKQAL+M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11881	uniprotkb:O35157	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	intact:EBI-8351080|intact:MINT-4104623	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559681|imex:IM-13625-13|dip:DIP-102620E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	psi-mi:"MI:0465"(dip)	-	comment:mint	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rigid:+XZ8ENxIZFZfflppHwgxSzuthXI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11881	uniprotkb:Q6PIE5	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559681|imex:IM-13625-13|dip:DIP-102620E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rigid:+XZ8ENxIZFZfflppHwgxSzuthXI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P11881	uniprotkb:Q8VDN2	intact:EBI-541478|uniprotkb:P20943|uniprotkb:Q99LG5|ensembl:ENSMUSP00000032192	intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09	psi-mi:itpr1_mouse(display_long)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)|uniprotkb:Inositol 1,4,5-trisphosphate-binding protein P400(gene name synonym)|uniprotkb:Purkinje cell protein 1(gene name synonym)|uniprotkb:Protein PCD-6(gene name synonym)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Pcd6(gene name synonym)|uniprotkb:Pcp1(gene name synonym)	psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559681|imex:IM-13625-13|dip:DIP-102620E	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_034715.3|refseq:XP_006505693.1|refseq:XP_006505699.1|refseq:XP_006505700.1|dip:DIP-32243N|refseq:XP_017176897.1|refseq:XP_017176899.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|mint:P11881|rcsb pdb:1N4K|rcsb pdb:1XZZ|rcsb pdb:5GUG|rcsb pdb:5X9Z|rcsb pdb:5XA0|rcsb pdb:5XA1|reactome:R-MMU-114508|reactome:R-MMU-139853|reactome:R-MMU-381676|reactome:R-MMU-418457|reactome:R-MMU-5578775|reactome:R-MMU-983695|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|ensembl:ENSMUSG00000030102(gene)|ensembl:ENSMUST00000032192(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)	refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:O+LA4/Acwos+RNtyqL3IgAe/kkk10090	rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090	rigid:+XZ8ENxIZFZfflppHwgxSzuthXI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O35157	uniprotkb:Q8VDN2	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559664|imex:IM-13625-12|dip:DIP-102618E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090	rigid:hLM3LZRGvhhvbNYaKMtU5AuMq6c	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q01484-2	uniprotkb:P32418	intact:EBI-941994|ensembl:ENSP00000378044	intact:EBI-2682189|uniprotkb:Q9UBL8|uniprotkb:Q9UDN1|uniprotkb:Q9UD55|uniprotkb:O95849|uniprotkb:Q587I6|uniprotkb:A8K6N1|uniprotkb:Q9UKX6|uniprotkb:Q9UDN2|uniprotkb:D6W595|ensembl:ENSP00000332931|ensembl:ENSP00000384763|uniprotkb:Q4QQG6|uniprotkb:Q59GN4	psi-mi:q01484-2(display_long)|uniprotkb:ANKB(gene name synonym)|uniprotkb:ANK2(gene name)|psi-mi:ANK2(display_short)|uniprotkb:Ankyrin-B(gene name synonym)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:Non-erythroid ankyrin(gene name synonym)	psi-mi:nac1_human(display_long)|uniprotkb:CNC(gene name synonym)|uniprotkb:NCX1(gene name synonym)|uniprotkb:"Na(+)/Ca(2+)-exchange protein 1"(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)|uniprotkb:SLC8A1(gene name)|psi-mi:SLC8A1(display_short)	psi-mi:"MI:0096"(pull down)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559641|imex:IM-13625-11|dip:DIP-102623E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-941975(ank2_human)|ensembl:ENSG00000145362(gene)|ensembl:ENST00000394537(transcript)	refseq:NP_001239553.1|refseq:XP_011531356.1|refseq:XP_011531357.1|refseq:XP_011531358.1|refseq:NP_001106271.1|refseq:NP_001106272.1|refseq:NP_001106273.1|refseq:NP_066920.1|refseq:XP_005264571.1|ensembl:ENSG00000183023(gene)|ensembl:ENST00000332839(transcript)|ensembl:ENST00000403092(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006936"(muscle contraction)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009749"(response to glucose)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0015491"("cation:cation antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0021537"(telencephalon development)|go:"GO:0030001"(metal ion transport)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0033198"(response to ATP)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044557"(relaxation of smooth muscle)|go:"GO:0045202"(synapse)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071944"(cell periphery)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098794"(postsynapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099580"(ion antiporter activity involved in regulation of postsynaptic membrane potential)|go:"GO:1901660"(calcium ion export)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905060"("calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration")|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5578775|refseq:XP_006712144.1|refseq:XP_006712145.1|refseq:XP_006712146.1|refseq:XP_006712147.1|refseq:XP_006712148.1|refseq:XP_016860235.1|refseq:XP_016860237.1|refseq:XP_016860238.1|refseq:XP_016860239.1|refseq:XP_016860240.1|refseq:XP_016860241.1|refseq:XP_016860242.1|refseq:XP_016860243.1|refseq:XP_016860247.1|dip:DIP-48356N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:e8xlbQGPZTukEz7l9hLOjjlgFxk9606	rogid:qx5nxfaXMDlhvCSwZi+EfEYV8rI9606	rigid:k4Bd+CD+SuIGxZSSrB6sqL2nQK4	false	green fluorescent protein tag:?-?|mutation disrupting interaction:1458-1458	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O35157	uniprotkb:Q8VDN2	intact:EBI-8351080|intact:MINT-4104623	intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09	psi-mi:o35157_mouse(display_long)|uniprotkb:Slc8a1(gene name)|psi-mi:Slc8a1(display_short)|uniprotkb:NCX1(gene name synonym)|uniprotkb:Sodium/calcium exchanger 1(gene name synonym)|uniprotkb:Solute carrier family 8 member 1(gene name synonym)	psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Mohler et al. (2005)	pubmed:16292983|doi:10.1371/journal.pbio.0030423|imex:IM-13625	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15559700|imex:IM-13625-14|dip:DIP-102618E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48354N|mint:O35157|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007154"(cell communication)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002987(Sodium/calcium exchanger, isoform 1)|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|interpro:IPR004836(Sodium/calcium exchanger protein)|interpro:IPR004837(Sodium/calcium exchanger membrane region)|interpro:IPR032452|interpro:IPR038081	refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N	psi-mi:"MI:0465"(dip)	comment:mint	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse)|taxid:10090(Mus musculus)	-	2017/08/04	2017/08/10	rogid:6nADmgH5dUS60NTYra3rWJdhVHc10090	rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090	rigid:hLM3LZRGvhhvbNYaKMtU5AuMq6c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)