#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P81303 uniprotkb:Q57612 intact:EBI-9026465|ensemblbacteria:AAB98109 intact:EBI-9026474|ensemblbacteria:AAB98132 psi-mi:nop10_metja(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:MJ0116.1(locus name) psi-mi:trub_metja(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:MJ0148(locus name) psi-mi:"MI:0077"(nuclear magnetic resonance) Hamma et al. (2005) pubmed:16286935|doi:10.1038/nsmb1036|imex:IM-21610 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15559345|imex:IM-21610-1|dip:DIP-192025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60500N|ensemblbacteria:AAB98109(transcript)|ensemblbacteria:MJ_0116.1(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2APO|rcsb pdb:2AQC refseq:WP_010869643.1|dip:DIP-60499N|ensemblbacteria:AAB98132(transcript)|ensemblbacteria:MJ_0148(gene)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2APO psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:ZsbX1SrWkh01X3Gofxxq4KqYBDQ243232 rogid:x4kuEVNhwEkSHpe/FUevqxrS11g243232 rigid:w7GxjhmDcNblLzR6uFwQ96iqgLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q6Q547 uniprotkb:Q57612 intact:EBI-2052475|uniprotkb:D3DL22|ensemblfungi:YHR072W-A intact:EBI-9026474|ensemblbacteria:AAB98132 psi-mi:nop10_yeast(display_long)|uniprotkb:YHR072W-A(locus name)|uniprotkb:Nucleolar protein family A member 3(gene name synonym)|uniprotkb:snoRNP protein NOP10(gene name synonym)|uniprotkb:NOP10(gene name)|psi-mi:NOP10(display_short)|uniprotkb:Nucleolar protein 10(gene name synonym) psi-mi:trub_metja(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:MJ0148(locus name) psi-mi:"MI:0077"(nuclear magnetic resonance) Hamma et al. (2005) pubmed:16286935|doi:10.1038/nsmb1036|imex:IM-21610 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15559379|imex:IM-21610-3|dip:DIP-192026E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_058135.1|sgd:S000007455|dip:DIP-5845N|mint:Q6Q547|ensemblfungi:YHR072W-A(gene)|ensemblfungi:YHR072W-A_mRNA(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR036756|rcsb pdb:1Y2Y|rcsb pdb:2AQA|rcsb pdb:3U28|rcsb pdb:3UAI refseq:WP_010869643.1|dip:DIP-60499N|ensemblbacteria:AAB98132(transcript)|ensemblbacteria:MJ_0148(gene)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2APO psi-mi:"MI:0465"(dip) crc64:4718D35AF7911FBA - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2017/08/04 2017/08/10 rogid:9m0x3DatObFwua2cbCQYMRKGqrU559292 rogid:x4kuEVNhwEkSHpe/FUevqxrS11g243232 rigid:UYIS23EMELVPT3qeO85hyYi/hQk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81303 uniprotkb:Q57612 intact:EBI-9026465|ensemblbacteria:AAB98109 intact:EBI-9026474|ensemblbacteria:AAB98132 psi-mi:nop10_metja(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:MJ0116.1(locus name) psi-mi:trub_metja(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:MJ0148(locus name) psi-mi:"MI:0226"(ion exchange chromatography) Hamma et al. (2005) pubmed:16286935|doi:10.1038/nsmb1036|imex:IM-21610 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15559396|imex:IM-21610-4|dip:DIP-192025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60500N|ensemblbacteria:AAB98109(transcript)|ensemblbacteria:MJ_0116.1(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2APO|rcsb pdb:2AQC refseq:WP_010869643.1|dip:DIP-60499N|ensemblbacteria:AAB98132(transcript)|ensemblbacteria:MJ_0148(gene)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2APO psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:ZsbX1SrWkh01X3Gofxxq4KqYBDQ243232 rogid:x4kuEVNhwEkSHpe/FUevqxrS11g243232 rigid:w7GxjhmDcNblLzR6uFwQ96iqgLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81303 uniprotkb:Q57612 intact:EBI-9026465|ensemblbacteria:AAB98109 intact:EBI-9026474|ensemblbacteria:AAB98132 psi-mi:nop10_metja(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:MJ0116.1(locus name) psi-mi:trub_metja(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:MJ0148(locus name) psi-mi:"MI:0114"(x-ray crystallography) Hamma et al. (2005) pubmed:16286935|doi:10.1038/nsmb1036|imex:IM-21610 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15559414|imex:IM-21610-5|dip:DIP-192025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60500N|ensemblbacteria:AAB98109(transcript)|ensemblbacteria:MJ_0116.1(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2APO|rcsb pdb:2AQC refseq:WP_010869643.1|dip:DIP-60499N|ensemblbacteria:AAB98132(transcript)|ensemblbacteria:MJ_0148(gene)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2APO psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:ZsbX1SrWkh01X3Gofxxq4KqYBDQ243232 rogid:x4kuEVNhwEkSHpe/FUevqxrS11g243232 rigid:w7GxjhmDcNblLzR6uFwQ96iqgLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81303 uniprotkb:Q57612 intact:EBI-9026465|ensemblbacteria:AAB98109 intact:EBI-9026474|ensemblbacteria:AAB98132 psi-mi:nop10_metja(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:MJ0116.1(locus name) psi-mi:trub_metja(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:MJ0148(locus name) psi-mi:"MI:0071"(molecular sieving) Hamma et al. (2005) pubmed:16286935|doi:10.1038/nsmb1036|imex:IM-21610 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0465"(DIP) intact:EBI-15559362|imex:IM-21610-2|dip:DIP-192025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60500N|ensemblbacteria:AAB98109(transcript)|ensemblbacteria:MJ_0116.1(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2APO|rcsb pdb:2AQC refseq:WP_010869643.1|dip:DIP-60499N|ensemblbacteria:AAB98132(transcript)|ensemblbacteria:MJ_0148(gene)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2APO psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:ZsbX1SrWkh01X3Gofxxq4KqYBDQ243232 rogid:x4kuEVNhwEkSHpe/FUevqxrS11g243232 rigid:w7GxjhmDcNblLzR6uFwQ96iqgLg false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P81303 uniprotkb:Q57612 intact:EBI-9026465|ensemblbacteria:AAB98109 intact:EBI-9026474|ensemblbacteria:AAB98132 psi-mi:nop10_metja(display_long)|uniprotkb:nop10(gene name)|psi-mi:nop10(display_short)|uniprotkb:MJ0116.1(locus name) psi-mi:trub_metja(display_long)|uniprotkb:truB(gene name)|psi-mi:truB(display_short)|uniprotkb:"tRNA pseudouridine(55) synthase"(gene name synonym)|uniprotkb:tRNA pseudouridylate synthase(gene name synonym)|uniprotkb:tRNA-uridine isomerase(gene name synonym)|uniprotkb:MJ0148(locus name) psi-mi:"MI:0096"(pull down) Hamma et al. (2005) pubmed:16286935|doi:10.1038/nsmb1036|imex:IM-21610 taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") taxid:243232(metja)|taxid:243232("Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-15559431|imex:IM-21610-6|dip:DIP-192025E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-60500N|ensemblbacteria:AAB98109(transcript)|ensemblbacteria:MJ_0116.1(gene)|go:"GO:0001522"(pseudouridine synthesis)|go:"GO:0006364"(rRNA processing)|go:"GO:0030515"(snoRNA binding)|interpro:IPR007264(Nucleolar RNA-binding protein Nop10p)|interpro:IPR023532|interpro:IPR036756|rcsb pdb:2APO|rcsb pdb:2AQC refseq:WP_010869643.1|dip:DIP-60499N|ensemblbacteria:AAB98132(transcript)|ensemblbacteria:MJ_0148(gene)|go:"GO:0000495"(box H/ACA RNA 3'-end processing)|go:"GO:0003723"(RNA binding)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0106029"(tRNA pseudouridine synthase activity)|go:"GO:1990481"(mRNA pseudouridine synthesis)|interpro:IPR002478(PUA)|interpro:IPR002501(tRNA pseudouridine synthase B, N-terminal)|interpro:IPR004521(Uncharacterized domain 2)|interpro:IPR004802(Putative rRNA pseudouridine synthase)|interpro:IPR012960(DKCLD)|interpro:IPR015947(PUA-like)|interpro:IPR020103|interpro:IPR026326|interpro:IPR032819|interpro:IPR036974|rcsb pdb:2APO psi-mi:"MI:0465"(dip) - - full coverage:Only protein-protein interactions|curation depth:imex curation taxid:562(ecolx)|taxid:562(Escherichia coli) - 2017/08/04 2017/08/10 rogid:ZsbX1SrWkh01X3Gofxxq4KqYBDQ243232 rogid:x4kuEVNhwEkSHpe/FUevqxrS11g243232 rigid:w7GxjhmDcNblLzR6uFwQ96iqgLg false - his tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)