#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q05086-2	uniprotkb:P68036-1	intact:EBI-10175863|ensembl:ENSP00000401265|ensembl:ENSP00000411258|ensembl:ENSP00000457771|ensembl:ENSP00000486349|ensembl:ENSP00000490111|ensembl:ENSP00000490557|ensembl:ENSP00000497549	intact:EBI-15556257|ensembl:ENSP00000344259	psi-mi:q05086-2(display_long)|uniprotkb:E6AP(gene name synonym)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym)	psi-mi:p68036-1(display_long)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)	psi-mi:"MI:0053"(fluorescence polarization spectroscopy)	Eletr et al. (2005)	doi:10.1038/nsmb984|pubmed:16142244|imex:IM-21786	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15556275|imex:IM-21786-1|dip:DIP-10996E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000114062(gene)|ensembl:ENST00000428984(transcript)|ensembl:ENST00000438097(transcript)|ensembl:ENST00000566215(transcript)|ensembl:ENST00000630424(transcript)|ensembl:ENST00000638011(transcript)|ensembl:ENST00000649550(transcript)|ensembl:ENST00000638155(transcript)|intact:EBI-954357(isoform-parent)|uniprotkb:Q05086-2(isoform-parent)	ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|intact:EBI-711173(isoform-parent)	psi-mi:"MI:0465"(dip)	isoform-comment:"Variant in position: 212:D->V (in AS, unknown pathological significance). Variant in position: 237:L->Q (in AS, unknown pathological significance). Variant in position: 263:L->W (in AS, unknown pathological significance). Variant in position: 458:P->L (in AS, unknown pathological significance). Variant in position: 545:G->R (in AS, unknown pathological significance). Variant in position: 584:E->Q (in AS, unknown pathological significance). Variant in position: 656:T->I (in AS, unknown pathological significance). Variant in position: 690:F->C (in AS, unknown pathological significance). Variant in position: 827:P->L (in AS, unknown pathological significance). Variant in position: 106:T->K (in AS, unknown pathological significance). Variant in position: 237:L->H (in AS, unknown pathological significance). Variant in position: 435:L->P (in AS, unknown pathological significance). Variant in position: 477:R->P (in AS, unknown pathological significance). Variant in position: 566:M->K (in AS, unknown pathological significance). Variant in position: 117:C->R (common polymorphism, may be associated with AS). Variant in position: 270:N->T (common polymorphism, may be associated with AS). Variant in position: 762:V->I (common polymorphism, may be associated with AS). Variant in position: 133:V->G (common polymorphism, may be associated with AS). Variant in position: 335:S->T (common polymorphism, may be associated with AS). Variant in position: 478:M->I (common polymorphism, may be associated with AS). Variant in position: 588:Q->E (common polymorphism, may be associated with AS). Variant in position: 588:Q->P (common polymorphism, may be associated with AS). Variant in position: 673:L->R (common polymorphism, may be associated with AS)."	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:HgylveTCwTfrwiB7WXj4Gmcc1EQ9606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rigid:zO15/DYZcgtFCO/CjksLDKrDd68	false	mutation:820-820|sufficient binding region:492-852	mutation decreasing interaction strength:63-63|bodipy label:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)