#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q00496	uniprotkb:P60880	intact:EBI-9119157|uniprotkb:Q45862	intact:EBI-524785|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:B2RAU4|uniprotkb:Q53EM2|uniprotkb:Q5U0B5|uniprotkb:D3DW16|uniprotkb:D3DW17|ensembl:ENSP00000254976	psi-mi:bxe_clobo(display_long)|uniprotkb:botE(gene name)|psi-mi:botE(display_short)|uniprotkb:Bontoxilysin-E(gene name synonym)	psi-mi:snp25_human(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:SNAP25(gene name)|psi-mi:SNAP25(display_short)|uniprotkb:SNAP(gene name synonym)	psi-mi:"MI:0435"(protease assay)	De et al. (2005)	pubmed:16131227|doi:10.1371/journal.pbio.0030323|imex:IM-9331	taxid:1491(clobo)|taxid:1491(Clostridium botulinum)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15556226|imex:IM-9331-1|dip:DIP-87847E	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_003372387.1|reactome:R-HSA-5250992|dip:DIP-46083N|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008289"(lipid binding)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0044156"(host cell junction)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0044164"(host cell cytosol)|go:"GO:0044231"(host cell presynaptic membrane)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0090729"(toxin activity)|interpro:IPR000395(Peptidase M27, bontoxilysin)|interpro:IPR011065(Kunitz inhibitor ST1-like)|interpro:IPR012500(Clostridium neurotoxin, translocation)|interpro:IPR012928(Clostridium neurotoxin, receptor binding N-terminal)|interpro:IPR013104(Clostridium neurotoxin, receptor-binding C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR036248|rcsb pdb:1T3A|rcsb pdb:1T3C|rcsb pdb:1ZKW|rcsb pdb:1ZKX|rcsb pdb:1ZL5|rcsb pdb:1ZL6|rcsb pdb:1ZN3|rcsb pdb:3FFZ|rcsb pdb:7K7Y|rcsb pdb:7K84	refseq:XP_005260865.1|refseq:XP_016883510.1|refseq:NP_003072.2|refseq:NP_570824.1|ensembl:ENSG00000132639(gene)|ensembl:ENST00000254976(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030426"(growth cone)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60880|rcsb pdb:1KIL|rcsb pdb:1XTG|rcsb pdb:2N1T|rcsb pdb:3DDA|rcsb pdb:3DDB|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:3ZUR|rcsb pdb:5W7I|rcsb pdb:5W7J|rcsb pdb:6JLH|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250968|reactome:R-HSA-5250971|reactome:R-HSA-5250992|reactome:R-HSA-6798695|reactome:R-HSA-888590|reactome:R-HSA-9662360|refseq:XP_016883511.1|refseq:NP_001309831.1|refseq:NP_001309832.1|refseq:NP_001309833.1|refseq:NP_001309834.1|refseq:NP_001309835.1|refseq:NP_001309836.1|refseq:NP_001309837.1|refseq:NP_001309838.1|refseq:NP_001309839.1|dip:DIP-34554N	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/04	2017/08/10	rogid:zOobvRGIyO5Ji/AoLT/+CNWua001491	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs9606	rigid:7QGlq2+rMQHmbF4zMBgljb66HoU	false	binding-associated region:2-422	-	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)