#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P10912	uniprotkb:P10912	intact:EBI-286316|uniprotkb:Q9HCX2|ensembl:ENSP00000230882|ensembl:ENSP00000442206|ensembl:ENSP00000478291|ensembl:ENSP00000478332|ensembl:ENSP00000479846|ensembl:ENSP00000482373	intact:EBI-286316|uniprotkb:Q9HCX2|ensembl:ENSP00000230882|ensembl:ENSP00000442206|ensembl:ENSP00000478291|ensembl:ENSP00000478332|ensembl:ENSP00000479846|ensembl:ENSP00000482373	psi-mi:ghr_human(display_long)|uniprotkb:Somatotropin receptor(gene name synonym)|uniprotkb:GHR(gene name)|psi-mi:GHR(display_short)	psi-mi:ghr_human(display_long)|uniprotkb:Somatotropin receptor(gene name synonym)|uniprotkb:GHR(gene name)|psi-mi:GHR(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Brown et al. (2005)	pubmed:16116438|doi:10.1038/nsmb977|imex:IM-21789	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15555954|imex:IM-21789-1|dip:DIP-192204E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000154.1|refseq:NP_001229328.1|refseq:NP_001229329.1|refseq:NP_001229330.1|refseq:NP_001229331.1|refseq:NP_001229332.1|refseq:NP_001229333.1|refseq:NP_001229334.1|refseq:NP_001229335.1|refseq:NP_001229389.1|refseq:NP_001229391.1|dip:DIP-630N|ensembl:ENSG00000112964(gene)|ensembl:ENST00000230882(transcript)|ensembl:ENST00000537449(transcript)|ensembl:ENST00000612382(transcript)|ensembl:ENST00000612626(transcript)|ensembl:ENST00000615111(transcript)|ensembl:ENST00000618088(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032094"(response to food)|go:"GO:0032355"(response to estradiol)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|rcsb pdb:1A22|rcsb pdb:1AXI|rcsb pdb:1HWG|rcsb pdb:1HWH|rcsb pdb:1KF9|rcsb pdb:2AEW|rcsb pdb:3HHR|rcsb pdb:5OEK|rcsb pdb:5OHD|reactome:R-HSA-1170546|reactome:R-HSA-982772	refseq:NP_000154.1|refseq:NP_001229328.1|refseq:NP_001229329.1|refseq:NP_001229330.1|refseq:NP_001229331.1|refseq:NP_001229332.1|refseq:NP_001229333.1|refseq:NP_001229334.1|refseq:NP_001229335.1|refseq:NP_001229389.1|refseq:NP_001229391.1|dip:DIP-630N|ensembl:ENSG00000112964(gene)|ensembl:ENST00000230882(transcript)|ensembl:ENST00000537449(transcript)|ensembl:ENST00000612382(transcript)|ensembl:ENST00000612626(transcript)|ensembl:ENST00000615111(transcript)|ensembl:ENST00000618088(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032094"(response to food)|go:"GO:0032355"(response to estradiol)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|rcsb pdb:1A22|rcsb pdb:1AXI|rcsb pdb:1HWG|rcsb pdb:1HWH|rcsb pdb:1KF9|rcsb pdb:2AEW|rcsb pdb:3HHR|rcsb pdb:5OEK|rcsb pdb:5OHD|reactome:R-HSA-1170546|reactome:R-HSA-982772	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	-	2017/08/04	2017/08/10	rogid:BJvy3kRKyIQhPb9K64+bTaOUxhg9606	rogid:BJvy3kRKyIQhPb9K64+bTaOUxhg9606	rigid:6s+uxWCBtXHp8C+cnOiKvuq7rFY	false	sufficient binding region:1-322|flag tag:n-n	sufficient binding region:1-322|ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P10912	uniprotkb:P10912	intact:EBI-286316|uniprotkb:Q9HCX2|ensembl:ENSP00000230882|ensembl:ENSP00000442206|ensembl:ENSP00000478291|ensembl:ENSP00000478332|ensembl:ENSP00000479846|ensembl:ENSP00000482373	intact:EBI-286316|uniprotkb:Q9HCX2|ensembl:ENSP00000230882|ensembl:ENSP00000442206|ensembl:ENSP00000478291|ensembl:ENSP00000478332|ensembl:ENSP00000479846|ensembl:ENSP00000482373	psi-mi:ghr_human(display_long)|uniprotkb:Somatotropin receptor(gene name synonym)|uniprotkb:GHR(gene name)|psi-mi:GHR(display_short)	psi-mi:ghr_human(display_long)|uniprotkb:Somatotropin receptor(gene name synonym)|uniprotkb:GHR(gene name)|psi-mi:GHR(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Brown et al. (2005)	pubmed:16116438|doi:10.1038/nsmb977|imex:IM-21789	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15556004|imex:IM-21789-3|dip:DIP-192204E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000154.1|refseq:NP_001229328.1|refseq:NP_001229329.1|refseq:NP_001229330.1|refseq:NP_001229331.1|refseq:NP_001229332.1|refseq:NP_001229333.1|refseq:NP_001229334.1|refseq:NP_001229335.1|refseq:NP_001229389.1|refseq:NP_001229391.1|dip:DIP-630N|ensembl:ENSG00000112964(gene)|ensembl:ENST00000230882(transcript)|ensembl:ENST00000537449(transcript)|ensembl:ENST00000612382(transcript)|ensembl:ENST00000612626(transcript)|ensembl:ENST00000615111(transcript)|ensembl:ENST00000618088(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032094"(response to food)|go:"GO:0032355"(response to estradiol)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|rcsb pdb:1A22|rcsb pdb:1AXI|rcsb pdb:1HWG|rcsb pdb:1HWH|rcsb pdb:1KF9|rcsb pdb:2AEW|rcsb pdb:3HHR|rcsb pdb:5OEK|rcsb pdb:5OHD|reactome:R-HSA-1170546|reactome:R-HSA-982772	refseq:NP_000154.1|refseq:NP_001229328.1|refseq:NP_001229329.1|refseq:NP_001229330.1|refseq:NP_001229331.1|refseq:NP_001229332.1|refseq:NP_001229333.1|refseq:NP_001229334.1|refseq:NP_001229335.1|refseq:NP_001229389.1|refseq:NP_001229391.1|dip:DIP-630N|ensembl:ENSG00000112964(gene)|ensembl:ENST00000230882(transcript)|ensembl:ENST00000537449(transcript)|ensembl:ENST00000612382(transcript)|ensembl:ENST00000612626(transcript)|ensembl:ENST00000615111(transcript)|ensembl:ENST00000618088(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032094"(response to food)|go:"GO:0032355"(response to estradiol)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|rcsb pdb:1A22|rcsb pdb:1AXI|rcsb pdb:1HWG|rcsb pdb:1HWH|rcsb pdb:1KF9|rcsb pdb:2AEW|rcsb pdb:3HHR|rcsb pdb:5OEK|rcsb pdb:5OHD|reactome:R-HSA-1170546|reactome:R-HSA-982772	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	-	2017/08/04	2017/08/10	rogid:BJvy3kRKyIQhPb9K64+bTaOUxhg9606	rogid:BJvy3kRKyIQhPb9K64+bTaOUxhg9606	rigid:6s+uxWCBtXHp8C+cnOiKvuq7rFY	false	sufficient binding region:241-275|yellow fluorescent protein tag:n-n	cyan fluorescent protein tag:n-n|sufficient binding region:241-275	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P19235	uniprotkb:P19235	intact:EBI-617321|uniprotkb:Q15443|uniprotkb:Q2M205|uniprotkb:B2RCG4|ensembl:ENSP00000222139	intact:EBI-617321|uniprotkb:Q15443|uniprotkb:Q2M205|uniprotkb:B2RCG4|ensembl:ENSP00000222139	psi-mi:epor_human(display_long)|uniprotkb:EPOR(gene name)|psi-mi:EPOR(display_short)	psi-mi:epor_human(display_long)|uniprotkb:EPOR(gene name)|psi-mi:EPOR(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Brown et al. (2005)	pubmed:16116438|doi:10.1038/nsmb977|imex:IM-21789	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15556029|imex:IM-21789-4|dip:DIP-192205E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000112.1|dip:DIP-5732N|rcsb pdb:1ERN|rcsb pdb:2JIX|rcsb pdb:2MV6|rcsb pdb:4Y5V|rcsb pdb:4Y5X|rcsb pdb:4Y5Y|rcsb pdb:6E2Q|rcsb pdb:6MOE|rcsb pdb:6MOF|rcsb pdb:6MOH|rcsb pdb:6MOI|rcsb pdb:6MOJ|rcsb pdb:6MOK|rcsb pdb:6MOL|reactome:R-HSA-9006335|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|ensembl:ENSG00000187266(gene)|ensembl:ENST00000222139(transcript)|go:"GO:0004900"(erythropoietin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0046697"(decidualization)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR009167(Erythropoietin receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR036116|mint:P19235|rcsb pdb:1CN4|rcsb pdb:1EBA|rcsb pdb:1EBP|rcsb pdb:1EER	refseq:NP_000112.1|dip:DIP-5732N|rcsb pdb:1ERN|rcsb pdb:2JIX|rcsb pdb:2MV6|rcsb pdb:4Y5V|rcsb pdb:4Y5X|rcsb pdb:4Y5Y|rcsb pdb:6E2Q|rcsb pdb:6MOE|rcsb pdb:6MOF|rcsb pdb:6MOH|rcsb pdb:6MOI|rcsb pdb:6MOJ|rcsb pdb:6MOK|rcsb pdb:6MOL|reactome:R-HSA-9006335|reactome:R-HSA-9027276|reactome:R-HSA-9027277|reactome:R-HSA-9027283|reactome:R-HSA-9027284|ensembl:ENSG00000187266(gene)|ensembl:ENST00000222139(transcript)|go:"GO:0004900"(erythropoietin receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0046697"(decidualization)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR009167(Erythropoietin receptor)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR036116|mint:P19235|rcsb pdb:1CN4|rcsb pdb:1EBA|rcsb pdb:1EBP|rcsb pdb:1EER	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	-	2017/08/04	2017/08/10	rogid:tQiA0I1YOgo0qGcgBDNJKvzkvMg9606	rogid:tQiA0I1YOgo0qGcgBDNJKvzkvMg9606	rigid:IWp3bFV5pq1ihQ2WlBWH+VFPcQI	false	yellow fluorescent protein tag:n-n	cyan fluorescent protein tag:n-n	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10912	uniprotkb:P10912	intact:EBI-286316|uniprotkb:Q9HCX2|ensembl:ENSP00000230882|ensembl:ENSP00000442206|ensembl:ENSP00000478291|ensembl:ENSP00000478332|ensembl:ENSP00000479846|ensembl:ENSP00000482373	intact:EBI-286316|uniprotkb:Q9HCX2|ensembl:ENSP00000230882|ensembl:ENSP00000442206|ensembl:ENSP00000478291|ensembl:ENSP00000478332|ensembl:ENSP00000479846|ensembl:ENSP00000482373	psi-mi:ghr_human(display_long)|uniprotkb:Somatotropin receptor(gene name synonym)|uniprotkb:GHR(gene name)|psi-mi:GHR(display_short)	psi-mi:ghr_human(display_long)|uniprotkb:Somatotropin receptor(gene name synonym)|uniprotkb:GHR(gene name)|psi-mi:GHR(display_short)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Brown et al. (2005)	pubmed:16116438|doi:10.1038/nsmb977|imex:IM-21789	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15556050|imex:IM-21789-5|dip:DIP-192204E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000154.1|refseq:NP_001229328.1|refseq:NP_001229329.1|refseq:NP_001229330.1|refseq:NP_001229331.1|refseq:NP_001229332.1|refseq:NP_001229333.1|refseq:NP_001229334.1|refseq:NP_001229335.1|refseq:NP_001229389.1|refseq:NP_001229391.1|dip:DIP-630N|ensembl:ENSG00000112964(gene)|ensembl:ENST00000230882(transcript)|ensembl:ENST00000537449(transcript)|ensembl:ENST00000612382(transcript)|ensembl:ENST00000612626(transcript)|ensembl:ENST00000615111(transcript)|ensembl:ENST00000618088(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032094"(response to food)|go:"GO:0032355"(response to estradiol)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|rcsb pdb:1A22|rcsb pdb:1AXI|rcsb pdb:1HWG|rcsb pdb:1HWH|rcsb pdb:1KF9|rcsb pdb:2AEW|rcsb pdb:3HHR|rcsb pdb:5OEK|rcsb pdb:5OHD|reactome:R-HSA-1170546|reactome:R-HSA-982772	refseq:NP_000154.1|refseq:NP_001229328.1|refseq:NP_001229329.1|refseq:NP_001229330.1|refseq:NP_001229331.1|refseq:NP_001229332.1|refseq:NP_001229333.1|refseq:NP_001229334.1|refseq:NP_001229335.1|refseq:NP_001229389.1|refseq:NP_001229391.1|dip:DIP-630N|ensembl:ENSG00000112964(gene)|ensembl:ENST00000230882(transcript)|ensembl:ENST00000537449(transcript)|ensembl:ENST00000612382(transcript)|ensembl:ENST00000612626(transcript)|ensembl:ENST00000615111(transcript)|ensembl:ENST00000618088(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032094"(response to food)|go:"GO:0032355"(response to estradiol)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|rcsb pdb:1A22|rcsb pdb:1AXI|rcsb pdb:1HWG|rcsb pdb:1HWH|rcsb pdb:1KF9|rcsb pdb:2AEW|rcsb pdb:3HHR|rcsb pdb:5OEK|rcsb pdb:5OHD|reactome:R-HSA-1170546|reactome:R-HSA-982772	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	-	2017/08/04	2017/08/10	rogid:BJvy3kRKyIQhPb9K64+bTaOUxhg9606	rogid:BJvy3kRKyIQhPb9K64+bTaOUxhg9606	rigid:6s+uxWCBtXHp8C+cnOiKvuq7rFY	false	sufficient binding region:1-322|yellow fluorescent protein tag:c-c	sufficient binding region:1-322|cyan fluorescent protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48357	uniprotkb:P48357	intact:EBI-518596|intact:EBI-1964991|intact:EBI-1965023|intact:EBI-1965042|intact:EBI-1759938|intact:EBI-1759955|intact:EBI-1759923|uniprotkb:Q13592|uniprotkb:Q13593|uniprotkb:Q13594|uniprotkb:Q92919|uniprotkb:Q92920|uniprotkb:Q92921|ensembl:ENSP00000330393	intact:EBI-518596|intact:EBI-1964991|intact:EBI-1965023|intact:EBI-1965042|intact:EBI-1759938|intact:EBI-1759955|intact:EBI-1759923|uniprotkb:Q13592|uniprotkb:Q13593|uniprotkb:Q13594|uniprotkb:Q92919|uniprotkb:Q92920|uniprotkb:Q92921|ensembl:ENSP00000330393	psi-mi:lepr_human(display_long)|uniprotkb:OB receptor(gene name synonym)|uniprotkb:HuB219(gene name synonym)|uniprotkb:LEPR(gene name)|psi-mi:LEPR(display_short)|uniprotkb:DB(gene name synonym)|uniprotkb:OBR(gene name synonym)	psi-mi:lepr_human(display_long)|uniprotkb:OB receptor(gene name synonym)|uniprotkb:HuB219(gene name synonym)|uniprotkb:LEPR(gene name)|psi-mi:LEPR(display_short)|uniprotkb:DB(gene name synonym)|uniprotkb:OBR(gene name synonym)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Brown et al. (2005)	pubmed:16116438|doi:10.1038/nsmb977|imex:IM-21789	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15556075|imex:IM-21789-6|dip:DIP-143632E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003679.1|refseq:NP_001003680.1|refseq:NP_001185616.1|refseq:NP_001185617.1|refseq:NP_001185618.1|refseq:NP_002294.2|dip:DIP-6117N|ensembl:ENSG00000116678(gene)|ensembl:ENST00000349533(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019953"(sexual reproduction)|go:"GO:0019955"(cytokine binding)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0038021"(leptin receptor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0044321"(response to leptin)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0051049"(regulation of transport)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098868"(bone growth)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015752(Leptin receptor)|interpro:IPR036116|interpro:IPR041182|rcsb pdb:3V6O|rcsb pdb:6E2P|reactome:R-HSA-2586552	refseq:NP_001003679.1|refseq:NP_001003680.1|refseq:NP_001185616.1|refseq:NP_001185617.1|refseq:NP_001185618.1|refseq:NP_002294.2|dip:DIP-6117N|ensembl:ENSG00000116678(gene)|ensembl:ENST00000349533(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019953"(sexual reproduction)|go:"GO:0019955"(cytokine binding)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0038021"(leptin receptor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0044321"(response to leptin)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0051049"(regulation of transport)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098868"(bone growth)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015752(Leptin receptor)|interpro:IPR036116|interpro:IPR041182|rcsb pdb:3V6O|rcsb pdb:6E2P|reactome:R-HSA-2586552	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2017/08/04	2017/08/10	rogid:vNif9Lpk4eP33Q1wzUAg5MvL2jk9606	rogid:vNif9Lpk4eP33Q1wzUAg5MvL2jk9606	rigid:C47MQrKE2nxgNfJL5OMi3doHIwI	false	yellow fluorescent protein tag:c-c	renilla luciferase protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P10912	uniprotkb:P10912	intact:EBI-286316|uniprotkb:Q9HCX2|ensembl:ENSP00000230882|ensembl:ENSP00000442206|ensembl:ENSP00000478291|ensembl:ENSP00000478332|ensembl:ENSP00000479846|ensembl:ENSP00000482373	intact:EBI-286316|uniprotkb:Q9HCX2|ensembl:ENSP00000230882|ensembl:ENSP00000442206|ensembl:ENSP00000478291|ensembl:ENSP00000478332|ensembl:ENSP00000479846|ensembl:ENSP00000482373	psi-mi:ghr_human(display_long)|uniprotkb:Somatotropin receptor(gene name synonym)|uniprotkb:GHR(gene name)|psi-mi:GHR(display_short)	psi-mi:ghr_human(display_long)|uniprotkb:Somatotropin receptor(gene name synonym)|uniprotkb:GHR(gene name)|psi-mi:GHR(display_short)	psi-mi:"MI:0012"(bioluminescence resonance energy transfer)	Brown et al. (2005)	pubmed:16116438|doi:10.1038/nsmb977|imex:IM-21789	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15555979|imex:IM-21789-2|dip:DIP-192204E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000154.1|refseq:NP_001229328.1|refseq:NP_001229329.1|refseq:NP_001229330.1|refseq:NP_001229331.1|refseq:NP_001229332.1|refseq:NP_001229333.1|refseq:NP_001229334.1|refseq:NP_001229335.1|refseq:NP_001229389.1|refseq:NP_001229391.1|dip:DIP-630N|ensembl:ENSG00000112964(gene)|ensembl:ENST00000230882(transcript)|ensembl:ENST00000537449(transcript)|ensembl:ENST00000612382(transcript)|ensembl:ENST00000612626(transcript)|ensembl:ENST00000615111(transcript)|ensembl:ENST00000618088(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032094"(response to food)|go:"GO:0032355"(response to estradiol)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|rcsb pdb:1A22|rcsb pdb:1AXI|rcsb pdb:1HWG|rcsb pdb:1HWH|rcsb pdb:1KF9|rcsb pdb:2AEW|rcsb pdb:3HHR|rcsb pdb:5OEK|rcsb pdb:5OHD|reactome:R-HSA-1170546|reactome:R-HSA-982772	refseq:NP_000154.1|refseq:NP_001229328.1|refseq:NP_001229329.1|refseq:NP_001229330.1|refseq:NP_001229331.1|refseq:NP_001229332.1|refseq:NP_001229333.1|refseq:NP_001229334.1|refseq:NP_001229335.1|refseq:NP_001229389.1|refseq:NP_001229391.1|dip:DIP-630N|ensembl:ENSG00000112964(gene)|ensembl:ENST00000230882(transcript)|ensembl:ENST00000537449(transcript)|ensembl:ENST00000612382(transcript)|ensembl:ENST00000612626(transcript)|ensembl:ENST00000615111(transcript)|ensembl:ENST00000618088(transcript)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004903"(growth hormone receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0019838"(growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032094"(response to food)|go:"GO:0032355"(response to estradiol)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042976"(activation of Janus kinase activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043278"(response to morphine)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046898"(response to cycloheximide)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070195"(growth hormone receptor complex)|go:"GO:0070555"(response to interleukin-1)|go:"GO:1901215"(negative regulation of neuron death)|interpro:IPR003528(Long hematopoietin receptor, single chain, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015152(Erythropoietin receptor, ligand binding)|interpro:IPR025871|interpro:IPR036116|rcsb pdb:1A22|rcsb pdb:1AXI|rcsb pdb:1HWG|rcsb pdb:1HWH|rcsb pdb:1KF9|rcsb pdb:2AEW|rcsb pdb:3HHR|rcsb pdb:5OEK|rcsb pdb:5OHD|reactome:R-HSA-1170546|reactome:R-HSA-982772	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops)	-	2017/08/04	2017/08/10	rogid:BJvy3kRKyIQhPb9K64+bTaOUxhg9606	rogid:BJvy3kRKyIQhPb9K64+bTaOUxhg9606	rigid:6s+uxWCBtXHp8C+cnOiKvuq7rFY	false	sufficient binding region:241-322|yellow fluorescent protein tag:c-c	sufficient binding region:241-322|renilla luciferase protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P48357	uniprotkb:P48357	intact:EBI-518596|intact:EBI-1964991|intact:EBI-1965023|intact:EBI-1965042|intact:EBI-1759938|intact:EBI-1759955|intact:EBI-1759923|uniprotkb:Q13592|uniprotkb:Q13593|uniprotkb:Q13594|uniprotkb:Q92919|uniprotkb:Q92920|uniprotkb:Q92921|ensembl:ENSP00000330393	intact:EBI-518596|intact:EBI-1964991|intact:EBI-1965023|intact:EBI-1965042|intact:EBI-1759938|intact:EBI-1759955|intact:EBI-1759923|uniprotkb:Q13592|uniprotkb:Q13593|uniprotkb:Q13594|uniprotkb:Q92919|uniprotkb:Q92920|uniprotkb:Q92921|ensembl:ENSP00000330393	psi-mi:lepr_human(display_long)|uniprotkb:OB receptor(gene name synonym)|uniprotkb:HuB219(gene name synonym)|uniprotkb:LEPR(gene name)|psi-mi:LEPR(display_short)|uniprotkb:DB(gene name synonym)|uniprotkb:OBR(gene name synonym)	psi-mi:lepr_human(display_long)|uniprotkb:OB receptor(gene name synonym)|uniprotkb:HuB219(gene name synonym)|uniprotkb:LEPR(gene name)|psi-mi:LEPR(display_short)|uniprotkb:DB(gene name synonym)|uniprotkb:OBR(gene name synonym)	psi-mi:"MI:0055"(fluorescent resonance energy transfer)	Brown et al. (2005)	pubmed:16116438|doi:10.1038/nsmb977|imex:IM-21789	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:2364"(proximity)	psi-mi:"MI:0465"(DIP)	intact:EBI-15556096|imex:IM-21789-7|dip:DIP-143632E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0584"(fluorescence acceptor)	psi-mi:"MI:0583"(fluorescence donor)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001003679.1|refseq:NP_001003680.1|refseq:NP_001185616.1|refseq:NP_001185617.1|refseq:NP_001185618.1|refseq:NP_002294.2|dip:DIP-6117N|ensembl:ENSG00000116678(gene)|ensembl:ENST00000349533(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019953"(sexual reproduction)|go:"GO:0019955"(cytokine binding)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0038021"(leptin receptor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0044321"(response to leptin)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0051049"(regulation of transport)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098868"(bone growth)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015752(Leptin receptor)|interpro:IPR036116|interpro:IPR041182|rcsb pdb:3V6O|rcsb pdb:6E2P|reactome:R-HSA-2586552	refseq:NP_001003679.1|refseq:NP_001003680.1|refseq:NP_001185616.1|refseq:NP_001185617.1|refseq:NP_001185618.1|refseq:NP_002294.2|dip:DIP-6117N|ensembl:ENSG00000116678(gene)|ensembl:ENST00000349533(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006909"(phagocytosis)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019953"(sexual reproduction)|go:"GO:0019955"(cytokine binding)|go:"GO:0030217"(T cell differentiation)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0038021"(leptin receptor activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0044321"(response to leptin)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0051049"(regulation of transport)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098868"(bone growth)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0150104"(transport across blood-brain barrier)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015752(Leptin receptor)|interpro:IPR036116|interpro:IPR041182|rcsb pdb:3V6O|rcsb pdb:6E2P|reactome:R-HSA-2586552	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10036(mesau)|taxid:10036("Mesocricetus auratus (Golden hamster)")	-	2017/08/04	2017/08/10	rogid:vNif9Lpk4eP33Q1wzUAg5MvL2jk9606	rogid:vNif9Lpk4eP33Q1wzUAg5MvL2jk9606	rigid:C47MQrKE2nxgNfJL5OMi3doHIwI	false	yellow fluorescent protein tag:c-c	cyan fluorescent protein tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)